Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration
Scherling, Carole S., Hall, Tracey, Berisha, Flora, Klepac, Kristen, Karydas, Anna, Coppola, Giovanni, Kramer, Joel H., Rabinovici, Gil, Ahlijanian, Michael, Miller, Bruce L., Seeley, William, Grinberg, Lea T., Rosen, Howard, Meredith Jr, Jere, Boxer, Adam L.
Published in Annals of neurology (01.01.2014)
Published in Annals of neurology (01.01.2014)
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Journal Article
Characterization of novel CSF Tau and ptau biomarkers for Alzheimer's disease
Meredith, Jr, Jere E, Sankaranarayanan, Sethu, Guss, Valerie, Lanzetti, Anthony J, Berisha, Flora, Neely, Robert J, Slemmon, J Randall, Portelius, Erik, Zetterberg, Henrik, Blennow, Kaj, Soares, Holly, Ahlijanian, Michael, Albright, Charles F
Published in PloS one (07.10.2013)
Published in PloS one (07.10.2013)
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Journal Article
FLT3 inhibitors added to induction therapy induce deeper remissions
Levis, Mark, Shi, Wenge, Chang, Ken, Laing, Christian, Pollner, Reinhold, Gocke, Christopher, Adams, Emily, Berisha, Flora, Lameh, Jelveh, Lesegretain, Arnaud
Published in Blood (02.01.2020)
Published in Blood (02.01.2020)
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Journal Article
Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy
Wagshal, Dana, Sankaranarayanan, Sethu, Guss, Valerie, Hall, Tracey, Berisha, Flora, Lobach, Iryna, Karydas, Anna, Voltarelli, Lisa, Scherling, Carole, Heuer, Hilary, Tartaglia, Maria Carmela, Miller, Zachary, Coppola, Giovanni, Ahlijanian, Michael, Soares, Holly, Kramer, Joel H, Rabinovici, Gil D, Rosen, Howard J, Miller, Bruce L, Meredith, Jere, Boxer, Adam L
Published in Journal of neurology, neurosurgery and psychiatry (01.03.2015)
Published in Journal of neurology, neurosurgery and psychiatry (01.03.2015)
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Journal Article
CSF biomarker variability in the Alzheimer's Association quality control program
Mattsson, Niklas, Andreasson, Ulf, Persson, Staffan, Carrillo, Maria C, Collins, Steven, Chalbot, Sonia, Cutler, Neal, Dufour-Rainfray, Diane, Fagan, Anne M, Heegaard, Niels H.H, Robin Hsiung, Ging-Yuek, Hyman, Bradley, Iqbal, Khalid, Lachno, D. Richard, Lleó, Alberto, Lewczuk, Piotr, Molinuevo, José L, Parchi, Piero, Regeniter, Axel, Rissman, Robert, Rosenmann, Hanna, Sancesario, Giuseppe, Schröder, Johannes, Shaw, Leslie M, Teunissen, Charlotte E, Trojanowski, John Q, Vanderstichele, Hugo, Vandijck, Manu, Verbeek, Marcel M, Zetterberg, Henrik, Blennow, Kaj, Käser, Stephan A
Published in Alzheimer's & dementia (01.05.2013)
Published in Alzheimer's & dementia (01.05.2013)
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Journal Article
Recommendations for Use and Fit-for-Purpose Validation of Biomarker Multiplex Ligand Binding Assays in Drug Development
Jani, Darshana, Allinson, John, Berisha, Flora, Cowan, Kyra J., Devanarayan, Viswanath, Gleason, Carol, Jeromin, Andreas, Keller, Steve, Khan, Masood U., Nowatzke, Bill, Rhyne, Paul, Stephen, Laurie
Published in The AAPS journal (01.01.2016)
Published in The AAPS journal (01.01.2016)
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Journal Article
Concordance between Bone Marrow and Peripheral Blood Samples for Assessment of FLT3 Internal Tandem Duplication (ITD) Mutations: Data from Patients Screened for Participation in Quantum-R, a Global, Randomized, Open-Label, Phase 3 Study Examining the Effect of Quizartinib Monotherapy Vs Salvage Chemotherapy on Overall Survival in Patients with FLT3 - ITD - Mutated AML Who Are Refractory to or Have Relapsed after First-Line Therapy
Khaled, Samer, Ganguly, Siddhartha, Perl, Alexander E., Kobayashi, Ken, Berisha, Flora, Ding, Wei, Lameh, Jelveh, Martinelli, Giovanni
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Abstract 784: Effect of co-mutations and FLT3 -ITD variant allele frequency (VAF) on response to quizartinib or salvage chemotherapy (SC) in relapsed/refractory (R/R) acute myeloid leukemia (AML)
Perl, Alexander E., Cortes, Jorge E., Ganguly, Siddhartha, Khaled, Samer K., Krämer, Alwin, Martinelli, Giovanni, Russell, Nigel H., Chang, Ken C., Kato, Kazunobu, Yan, Yuhu, Xu, Li-An, Korkhov, Sergey, Günnel, Tobias, Sumi, Hiroyuki, Lesegretain, Arnaud, Berisha, Flora, Mires, Derek, Benzohra, Aziz, Isoyama, Takeshi, Santos, Cedric Dos, Levis, Mark J.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Development of a Novel Next-Generation Sequencing (NGS)-Based Assay for Measurable Residual Disease (MRD) in FLT3-ITD AML and Its Potential Clinical Application in Patients Treated with Chemotherapy Plus FLT3 Inhibitors
Levis, Mark J., Shi, Wenge, Chang, Ken CN, Laing, Christian, Berisha, Flora, Adams, Emily, Gocke, Christopher D, Ding, Wei, Nakamaru, Kenji, Lameh, Jelveh, Pollner, Reinhold, Kobayashi, Ken
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers
Soares, Holly D, Gasior, Maciej, Toyn, Jeremy H, Wang, Jun-Sheng, Hong, Quan, Berisha, Flora, Furlong, Michael T, Raybon, Joseph, Lentz, Kimberley A, Sweeney, Francis, Zheng, Naiyu, Akinsanya, Billy, Berman, Robert M, Thompson, Lorin A, Olson, Richard E, Morrison, John, Drexler, Dieter M, Macor, John E, Albright, Charlie F, Ahlijanian, Michael K, AbuTarif, Malaz
Published in The Journal of pharmacology and experimental therapeutics (01.07.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2016)
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Journal Article
Effect of Co-Mutations and FLT3-ITD Variant Allele Frequency (VAF) on Response to Quizartinib or Salvage Chemotherapy (SC) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)
Perl, Alexander E., Cortes, Jorge E., Ganguly, Siddhartha, Khaled, Samer K., Krämer, Alwin, Martinelli, Giovanni, Russell, Nigel H., Chang, Ken CN, Mires, Derek E., Kato, Kazunobu, Zhang, Yufen, Korkhov, Sergey, Wang, Zhenyu, Günnel, Tobias, Sumi, Hiroyuki, Isoyama, Takeshi, Lesegretain, Arnaud, Berisha, Flora, Dos Santos, Cedric E., Levis, Mark J.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
2021 White Paper on Recent Issues in Bioanalysis: TAb/NAb, Viral Vector CDx, Shedding Assays; CRISPR/Cas9 & CAR-T Immunogenicity; PCR & Vaccine Assay Performance; ADA Assay Comparability & Cut Point Appropriateness
Loo, Lina, Harris, Shannon, Milton, Mark, Meena, Lembke, Wibke, Berisha, Flora, Bertholet, Sylvie, Dessy, Francis, Dodge, Robert, Fang, Xiaodong, Fiscella, Michele, Garofolo, Fabio, Gorovits, Boris, Gupta, Soumi, Jawa, Vibha, Ishii-Watabe, Akiko, Long, Brian, Lu, Yanmei, Mack, Timothy, McGuire, Kristina, Nolan, Katrina, Pan, Luying, Potthoff, Bernd, Purushothama, Shobha, Smith, Dean, Solstad, Therese, Sonderegger, Ivo, Taddeo, Frank, Tangri, Shabnam, Wagner, Leslie, Wu, Bonnie, Xu, Yuanxin, Kirshner, Susan, Verthelyi, Daniela, Yan, Haoheng, Maxfield, Kimberly, Pedras-Vasconcelos, Joao, Abhari, Mohsen Rajabi, Gupta, Swati, Wu, Yuling, Rajadhyaksha, Manoj, Andisik, Matthew, Baltrukonis, Daniel, Cherry, Elana, Cludts, Isabelle, Gunn, George, Millner, Anders Holm, Jordan, Gregor, Kar, Sumit, Kubiak, Robert, Lotz, Gregor P, Palmer, Rachel, Peng, Kun, Poetzl, Johann, Richards, Susan, Savoie, Natasha, Staack, Roland F, Stubenrauch, Kay, Wadhwa, Meenu, Waxenecker, Günter, Yang, Tong-Yuan, Zhang, Lucia
Published in Bioanalysis (01.06.2022)
Published in Bioanalysis (01.06.2022)
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2021 White Paper on Recent Issues in Bioanalysis: ISR for Biomarkers, Liquid Biopsies, Spectral Cytometry, Inhalation/Oral & Multispecific Biotherapeutics, Accuracy/LLOQ for Flow Cytometry
Hersey, Sarah, Keller, Steve, Mathews, Joel, King, Lindsay, Bandukwala, Abbas, Berisha, Flora, Birchler, Mary, Bower, Joe, Clausen, Valerie, Duarte, Jose, Garofolo, Fabio, Hopper, Shirley, Kar, Sumit, Mabrouk, Omar, Marshall, Jean-Claude, McGuire, Kristina, Naughton, Michael, Saito, Yoshiro, Schuhmann, Imelda, Sperinde, Gizette, Teixeira, Priscila, Vitaliti, Alessandra, Wang, Yow-Ming, Wnek, Richard, Zhang, Yan, Spitz, Sue, Decman, Vilma, Eck, Steven, Estevam, Jose, Goihberg, Polina, Alcaide, Enrique Gómez, Gonneau, Christèle, Hedrick, Michael Nathan, Hopkins, Gregory, Junker, Fabian, Nuti, Sandra, Sommer, Ulrike, Standifer, Nathan, Stevens, Chad, Stevens, Erin, Hendricks, Carrie, Wadhwa, Meenu, Torri, Albert, Ma, Mark, Harris, Shannon, Kumar, Seema, Partridge, Michael A, Caiazzo, Teresa, Chilewski, Shannon, Cludts, Isabelle, Coble, Kelly, Gorovits, Boris, Grimaldi, Christine, Jordan, Gregor, Kamerud, John, Leary, Beth, Liang, Meina, Lim, Hanjo, Mayer, Andrew, O'Connor, Ellen, Palackal, Nisha, Poetzl, Johann, Prior, Sandra, Abhari, Mohsen Rajabi, Savoie, Natasha, Soo, Catherine, Ware, Mark, Wu, Bonnie, Xu, Yang, Yang, Tong-Yuan, Zoghbi, Jad
Published in Bioanalysis (01.05.2022)
Published in Bioanalysis (01.05.2022)
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2017 White Paper on recent issues in bioanalysis: a global perspective on immunogenicity guidelines & biomarker assay performance (Part 3 - LBA: immunogenicity, biomarkers and PK assays)
Gupta, Shalini, Richards, Susan, Amaravadi, Lakshmi, Piccoli, Steven, Desilva, Binodh, Pillutla, Renuka, Stevenson, Lauren, Mehta, Devangi, Carrasco-Triguero, Montserrat, Neely, Robert, Partridge, Michael, Staack, Roland F, Zhao, Xuemei, Gorovits, Boris, Kolaitis, Gerry, Sumner, Giane, Stubenrauch, Kay-Gunnar, Zou, Linglong, Amur, Shashi, Beaver, Chris, Berger, Isabella, Berisha, Flora, Birnboeck, Herbert, Bower, Joe, Cho, Seongeun (Julia), Cludts, Isabelle, Cocea, Laurent, Donato, Lorella Di, Fischer, Saloumeh, Fraser, Stephanie, Garofolo, Fabio, Haidar, Sam, Haulenbeek, Jonathan, Hottenstein, Charles, Hu, Jenny, Ishii-Watabe, Akiko, Islam, Rafiq, Jani, Darshana, Kadavil, John, Kamerud, John, Kramer, Daniel, Kurki, Pekka, MacMannis, Stephen, McNally, Jim, Mullan, Ashley, Papadimitriou, Apollon, Pedras-Vasconcelos, João, Ray, Soma, Safavi, Afshin, Saito, Yoshiro, Savoie, Natasha, Fjording, Marianne Scheel, Scheibner, Kara, Smeraglia, John, Song, An, Stouffer, Bruce, Tampal, Nilufer, der Strate, Barry van, Verch, Thorsten, Welink, Jan, Xu, Yuanxin, Yang, Tong-yuan, Yengi, Lilian, Zeng, Jianing, Zhang, Yan, Zhang, Yanhua, Zoog, Stephen
Published in Bioanalysis (01.12.2017)
Published in Bioanalysis (01.12.2017)
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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity)
Richards, Susan, Amaravadi, Lakshmi, Pillutla, Renuka, Birnboeck, Herbert, Torri, Albert, Cowan, Kyra J, Papadimitriou, Apollon, Garofolo, Fabio, Satterwhite, Christina, Piccoli, Steven, Wu, Bonnie, Krinos-Fiorotti, Corinna, Allinson, John, Berisha, Flora, Cocea, Laurent, Croft, Stephanie, Fraser, Stephanie, Galliccia, Fabrizio, Gorovits, Boris, Gupta, Swati, Gupta, Vinita, Haidar, Sam, Hottenstein, Charles, Ishii-Watabe, Akiko, Jani, Darshana, Kadavil, John, Kamerud, John, Kramer, Daniel, Litwin, Virginia, Lima Santos, Gustavo Mendes, Nelson, Robert, Ni, Yan, Pedras-Vasconcelos, João, Qiu, Yongchang, Rhyne, Paul, Safavi, Afshin, Saito, Yoshiro, Savoie, Natasha, Scheibner, Kara, Schick, Eginhard, Siguenza, Patricia Y, Smeraglia, John, Staack, Roland F, Subramanyam, Meena, Sumner, Giane, Thway, Theingi, Uhlinger, David, Ullmann, Martin, Vitaliti, Alessandra, Welink, Jan, Whiting, Chan C, Xue, Li, Zeng, Rong
Published in Bioanalysis (01.12.2016)
Published in Bioanalysis (01.12.2016)
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Journal Article
Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects
Toyn, Jeremy H, Boy, Kenneth M, Raybon, Joseph, Meredith, Jr, Jere E, Robertson, Alan S, Guss, Valerie, Hoque, Nina, Sweeney, Francis, Zhuo, Xiaoliang, Clarke, Wendy, Snow, Kimberly, Denton, R Rex, Zuev, Dmitry, Thompson, Lorin A, Morrison, John, Grace, James, Berisha, Flora, Furlong, Michael, Wang, Jun-Sheng, Lentz, Kimberly A, Padmanabha, Ramesh, Cook, Lynda, Wei, Cong, Drexler, Dieter M, Macor, John E, Albright, Charlie F, Gasior, Maciej, Olson, Richard E, Hong, Quan, Soares, Holly D, AbuTarif, Malaz, Ahlijanian, Michael K
Published in The Journal of pharmacology and experimental therapeutics (01.07.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2016)
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Journal Article
CSF neurofilament concentration reflects disease severity in frontotemporal degeneration
Scherling, Carole S., Hall, Tracey, Berisha, Flora, Klepac, Kristen, Karydas, Anna, Coppola, Giovanni, Kramer, Joel H., Rabinovici, Gil, Ahlijanian, Michael, Miller, Bruce L., Seeley, William, Grinberg, Lea T., Rosen, Howard, Meredith, Jere, Boxer, Adam L.
Published in Annals of neurology (01.01.2014)
Published in Annals of neurology (01.01.2014)
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Journal Article
Baseline CSF BETA-AMYLOID 42 correlates with ApoE genotype and baseline cognitive status in a phase II avagacestat predementia Alzheimer's disease study
Soares, Holly, Berisha, Flora, Gleason, Carol, Green, George, Tiller, Jane, Piccoli, Stephen, Burns, Leah, Berman, Robert, Kaplita, Stephen, Coric, Vlad
Published in Alzheimer's & dementia (2013)
Published in Alzheimer's & dementia (2013)
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Journal Article
Addressing drug effects on cut point determination for an anti-drug antibody assay
Barbosa, Maria D.F.S., Gleason, Carol R., Phillips, Kelli R., Berisha, Flora, Stouffer, Bruce, Warrack, Bethanne M., Chen, Guodong
Published in Journal of immunological methods (31.10.2012)
Published in Journal of immunological methods (31.10.2012)
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Journal Article
Reproducibility of a fully automated chemiluminescent tau assay
Tweedie, Anne, Green, George, Soares, Holly, Berisha, Flora, Neely, Robert, Baburina, Irina, Salamone, Salvatore, Kozo, Daniel, Jackson, Shari, Ackles, Karen, Byrne, Deb, DiMagno, Lisa
Published in Alzheimer's & dementia (01.07.2013)
Published in Alzheimer's & dementia (01.07.2013)
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