Adipose Triglyceride Lipase and Hormone-sensitive Lipase Are the Major Enzymes in Adipose Tissue Triacylglycerol Catabolism
Schweiger, Martina, Schreiber, Renate, Haemmerle, Guenter, Lass, Achim, Fledelius, Christian, Jacobsen, Poul, Tornqvist, Hans, Zechner, Rudolf, Zimmermann, Robert
Published in The Journal of biological chemistry (29.12.2006)
Published in The Journal of biological chemistry (29.12.2006)
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Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats
Jensen, Victoria Svop, Hvid, Henning, Damgaard, Jesper, Nygaard, Helle, Ingvorsen, Camilla, Wulff, Erik Max, Lykkesfeldt, Jens, Fledelius, Christian
Published in Diabetology and metabolic syndrome (24.01.2018)
Published in Diabetology and metabolic syndrome (24.01.2018)
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Temporal Development of Dyslipidemia and Nonalcoholic Fatty Liver Disease (NAFLD) in Syrian Hamsters Fed a High-Fat, High-Fructose, High-Cholesterol Diet
Svop Jensen, Victoria, Fledelius, Christian, Max Wulff, Erik, Lykkesfeldt, Jens, Hvid, Henning
Published in Nutrients (01.02.2021)
Published in Nutrients (01.02.2021)
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Journal Article
Adipose triglyceride lipase in human skeletal muscle is upregulated by exercise training
Alsted, Thomas J, Nybo, Lars, Schweiger, Martina, Fledelius, Christian, Jacobsen, Poul, Zimmermann, Robert, Zechner, Rudolf, Kiens, Bente
Published in American journal of physiology: endocrinology and metabolism (01.03.2009)
Published in American journal of physiology: endocrinology and metabolism (01.03.2009)
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Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones
Pedersen, Kent, Andersen, Helle, Fledelius, Christian, Holst, Jens Juul, Hjuler, Sara Toftegaard, Kuhre, Rune Ehrenreich
Published in Molecular metabolism (Germany) (01.03.2023)
Published in Molecular metabolism (Germany) (01.03.2023)
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Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD
Jensen, Victoria Svop, Fledelius, Christian, Zachodnik, Christina, Damgaard, Jesper, Nygaard, Helle, Tornqvist, Kristina Steinicke, Kirk, Rikke Kaae, Viuff, Birgitte Martine, Wulff, Erik Max, Lykkesfeldt, Jens, Hvid, Henning
Published in Journal of translational medicine (17.02.2021)
Published in Journal of translational medicine (17.02.2021)
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Journal Article
Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)
Mayer, Nicole, Schweiger, Martina, Melcher, Michaela-Christina, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Published in Bioorganic & medicinal chemistry (15.06.2015)
Published in Bioorganic & medicinal chemistry (15.06.2015)
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The Critical Role of Neutral Cholesterol Ester Hydrolase 1 in Cholesterol Removal From Human Macrophages
Igarashi, Masaki, Osuga, Jun-ichi, Uozaki, Hiroshi, Sekiya, Motohiro, Nagashima, Shuichi, Takahashi, Manabu, Takase, Satoru, Takanashi, Mikio, Li, Yongxue, Ohta, Keisuke, Kumagai, Masayoshi, Nishi, Makiko, Hosokawa, Masakiyo, Fledelius, Christian, Jacobsen, Poul, Yagyu, Hiroaki, Fukayama, Masashi, Nagai, Ryozo, Kadowaki, Takashi, Ohashi, Ken, Ishibashi, Shun
Published in Circulation research (26.11.2010)
Published in Circulation research (26.11.2010)
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Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts
Hvid, Henning, Blouin, Marie-José, Birman, Elena, Damgaard, Jesper, Poulsen, Fritz, Fels, Johannes Josef, Fledelius, Christian, Hansen, Bo Falck, Pollak, Michael
Published in PloS one (18.11.2013)
Published in PloS one (18.11.2013)
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Adipose weight gain during chronic insulin treatment of mice results from changes in lipid storage without affecting de novo synthesis of palmitate
Frikke-Schmidt, Henriette, Pedersen, Thomas Åskov, Fledelius, Christian, Olsen, Grith Skytte, Hellerstein, Marc
Published in PloS one (17.09.2013)
Published in PloS one (17.09.2013)
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Journal Article
Diabetic Phenotype in the Small Intestine of Zucker Diabetic Fatty Rats
Hvid, Henning, Jensen, Stina Rikke, Witgen, Brent M., Fledelius, Christian, Damgaard, Jesper, Pyke, Charles, Rasmussen, Thomas Bovbjerg
Published in Digestion (01.01.2016)
Published in Digestion (01.01.2016)
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Systemic Administration of the Long-Acting GLP-1 Derivative NN2211 Induces Lasting and Reversible Weight Loss in Both Normal and Obese Rats
LARSEN, Philip J, FLEDELIUS, Christian, KNUDSEN, Lotte Bjerre, TANG-CHRISTENSEN, Mads
Published in Diabetes (New York, N.Y.) (01.11.2001)
Published in Diabetes (New York, N.Y.) (01.11.2001)
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Clinical evaluation of the Serum CrossLaps One Step ELISA, a new assay measuring the serum concentration of bone-derived degradation products of type I collagen C-telopeptides
Christgau, Stephan, Rosenquist, Christian, Alexandersen, Peter, Bjarnason, Nina Hannover, Ravn, Pernille, Fledelius, Christian, Herling, Christian, Qvist, Per, Christiansen, Claus
Published in Clinical chemistry (Baltimore, Md.) (01.11.1998)
Published in Clinical chemistry (Baltimore, Md.) (01.11.1998)
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Oral administration of glucose promotes intracellular partitioning of fatty acid toward storage in white but not in red muscle
Fosgerau, Keld, Fledelius, Christian, Pedersen, Kent E, Kristensen, Jesper B, Daugaard, Jens R, Iglesias, Miguel A, Kraegen, Edward W, Furler, Stuart M
Published in Journal of endocrinology (01.09.2006)
Published in Journal of endocrinology (01.09.2006)
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Molecular Engineering of Insulin Icodec, the First Acylated Insulin Analog for Once-Weekly Administration in Humans
Kjeldsen, Thomas B, Hubálek, František, Hjørringgaard, Claudia U, Tagmose, Tina M, Nishimura, Erica, Stidsen, Carsten E, Porsgaard, Trine, Fledelius, Christian, Refsgaard, Hanne H. F, Gram-Nielsen, Sanne, Naver, Helle, Pridal, Lone, Hoeg-Jensen, Thomas, Jeppesen, Claus Bekker, Manfè, Valentina, Ludvigsen, Svend, Lautrup-Larsen, Inger, Madsen, Peter
Published in Journal of medicinal chemistry (08.07.2021)
Published in Journal of medicinal chemistry (08.07.2021)
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Journal Article
Development of small-molecule inhibitors targeting adipose triglyceride lipase
Mayer, Nicole, Schweiger, Martina, Romauch, Matthias, Grabner, Gernot F, Eichmann, Thomas O, Fuchs, Elisabeth, Ivkovic, Jakov, Heier, Christoph, Mrak, Irina, Lass, Achim, Höfler, Gerald, Fledelius, Christian, Zechner, Rudolf, Zimmermann, Robert, Breinbauer, Rolf
Published in Nature chemical biology (01.12.2013)
Published in Nature chemical biology (01.12.2013)
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Correction to: Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia
Castillo‑Armengol, Judit, Marzetta, Flavia, Sanchez-Archidona, Ana Rodriguez, Fledelius, Christian, Evans, Mark, McNeilly, Alison, McCrimmon, Rory J., Ibberson, Mark, Thorens, Bernard
Published in Diabetologia (01.02.2024)
Published in Diabetologia (01.02.2024)
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Journal Article
Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia
Castillo-Armengol, Judit, Marzetta, Flavia, Rodriguez Sanchez-Archidona, Ana, Fledelius, Christian, Evans, Mark, McNeilly, Alison, McCrimmon, Rory J., Ibberson, Mark, Thorens, Bernard
Published in Diabetologia (01.02.2024)
Published in Diabetologia (01.02.2024)
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