Scalable Synthesis and Isolation of the Four Stereoisomers of Methyl 1-Amino-3-(4-bromophenyl)cyclopentanecarboxylate, Useful Intermediates for the Synthesis of S1P1 Receptor Agonists
Wallace, Grier A, Gordon, Thomas D, Hayes, Martin E, Konopacki, Donald B, Fix-Stenzel, Shannon R, Zhang, Xiaolei, Grongsaard, Pintipa, Cusack, Kevin P, Schaffter, Lisa M, Henry, Rodger F, Stoffel, Robert H
Published in Journal of organic chemistry (03.07.2009)
Published in Journal of organic chemistry (03.07.2009)
Get full text
Journal Article
Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H4 Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models
Cowart, Marlon D, Altenbach, Robert J, Liu, Huaqing, Hsieh, Gin C, Drizin, Irene, Milicic, Ivan, Miller, Thomas R, Witte, David G, Wishart, Neil, Fix-Stenzel, Shannon R, McPherson, Michael J, Adair, Ronald M, Wetter, Jill M, Bettencourt, Brian M, Marsh, Kennan C, Sullivan, James P, Honore, Prisca, Esbenshade, Timothy A, Brioni, Jorge D
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
Get full text
Journal Article
Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H4 Receptor Ligands
Altenbach, Robert J, Adair, Ronald M, Bettencourt, Brian M, Black, Lawrence A, Fix-Stenzel, Shannon R, Gopalakrishnan, Sujatha M, Hsieh, Gin C, Liu, Huaqing, Marsh, Kennan C, McPherson, Michael J, Milicic, Ivan, Miller, Thomas R, Vortherms, Timothy A, Warrior, Usha, Wetter, Jill M, Wishart, Neil, Witte, David G, Honore, Prisca, Esbenshade, Timothy A, Hancock, Arthur A, Brioni, Jorge D, Cowart, Marlon D
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
Get full text
Journal Article
A stereoselective and scalable synthesis of a conformationally constrained S1P1 agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (01.07.2009)
Published in Tetrahedron letters (01.07.2009)
Get full text
Journal Article
Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H-4 Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models
Cowart, Marlon D., Altenbach, Robert J., Liu, Huaqing, Hsieh, Gin C., Drizin, Irene, Milicic, Ivan, Miller, Thomas R., Witte, David G., Wishart, Neil, Fix-Stenzel, Shannon R., McPherson, Michael J., Adair, Ronald M., Wetter, Jill M., Bettencourt, Brian M., Marsh, Kerman C., Sullivan, James P., Honore, Prisca, Esbenshade, Timothy A., Brioni, Jorge D.
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
Get full text
Journal Article
NOVEL OXADIAZOLE COMPOUNDS
FIX STENZEL SHANNON, WOLLER KEVIN R, GRONGSAARD PINTIPA, BREINLINGER ERIC C, ANSELL GRAHAM K, HOBSON ADRIAN D, CUSACK KEVIN P, STOFFEL ROBERT H
Year of Publication 09.09.2009
Get full text
Year of Publication 09.09.2009
Patent
Structure-Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H-4 Receptor Ligands
Altenbach, Robert J., Adair, Ronald M., Bettencourt, Brian M., Black, Lawrence A., Fix-Stenzel, Shannon R., Gopalakrishnan, Suiatha M., Hsieh, Gin C., Liu, Huaqing, Marsh, Kennan C., McPherson, Michael J., Milicic, Ivan, Miller, Thomas R., Vortherms, Timothy A., Warrior, Usha, Wetter, Jill M., Wishart, Neil, Witte, David G., Honore, Prisca, Esbenshade, Timothy A., Hancock, Arthur A., Brioni, Jorge D., Cowart, Marlon D.
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
Get full text
Journal Article
Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-alpha production
Cusack, Kevin, Allen, Hamish, Bischoff, Agnieszka, Clabbers, Anca, Dixon, Richard, Fix-Stenzel, Shannon, Friedman, Michael, Gaumont, Yvette, George, Dawn, Gordon, Thomas, Grongsaard, Pintipa, Janssen, Bernd, Jia, Yong, Moskey, Maria, Quinn, Christopher, Salmeron, Andres, Thomas, Christine, Wallace, Grier, Wishart, Neil, Yu, Zhengtian
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Get full text
Journal Article
A stereoselective and scalable synthesis of a conformationally constrained S1P(1) agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (15.07.2009)
Published in Tetrahedron letters (15.07.2009)
Get full text
Journal Article
Discovery of thieno[2,3- c]pyridines as potent COT inhibitors
George, Dawn, Friedman, Michael, Allen, Hamish, Argiriadi, Maria, Barberis, Claude, Bischoff, Agnieszka, Clabbers, Anca, Cusack, Kevin, Dixon, Richard, Fix-Stenzel, Shannon, Gordon, Thomas, Janssen, Bernd, Jia, Yong, Moskey, Maria, Quinn, Christopher, Salmeron, Jose-Andres, Wishart, Neil, Woller, Kevin, Yu, Zhengtian
Published in Bioorganic & medicinal chemistry (15.09.2008)
Published in Bioorganic & medicinal chemistry (15.09.2008)
Get full text
Journal Article
A stereoselective and scalable synthesis of a conformationally constrained S1P 1 agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (2009)
Published in Tetrahedron letters (2009)
Get full text
Journal Article
Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-a production
CUSACK, Kevin, ALLEN, Hamish, GRONGSAARD, Pintipa, JANSSEN, Bernd, YONG JIA, MOSKEY, Maria, QUINN, Christopher, SALMERON, Andres, THOMAS, Christine, WALLACE, Grier, WISHART, Neil, ZHENGTIAN YU, BISCHOFF, Agnieszka, CLABBERS, Anca, DIXON, Richard, FIX-STENZEL, Shannon, FRIEDMAN, Michael, GAUMONT, Yvette, GEORGE, Dawn, GORDON, Thomas
Published in Bioorganic & medicinal chemistry letters (2009)
Get full text
Published in Bioorganic & medicinal chemistry letters (2009)
Journal Article
NOVEL OXADIAZOLE COMPOUNDS
WOLLER, KEVIN, R, BREINLINGER, ERIC, C, CUSACK, KEVIN, P, FIX-STENZEL, SHANNON, R, STOFFEL, ROBERT, H
Year of Publication 04.09.2013
Get full text
Year of Publication 04.09.2013
Patent
Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases
MICHAELIDES MICHAEL R, JI ZHIQIN, SORENSEN BRYAN K, FIX-STENZEL SHANNON R, CLARK RICHARD F, JUDD ANDREW S
Year of Publication 08.04.2014
Get full text
Year of Publication 08.04.2014
Patent