Scalable Synthesis and Isolation of the Four Stereoisomers of Methyl 1-Amino-3-(4-bromophenyl)cyclopentanecarboxylate, Useful Intermediates for the Synthesis of S1P1 Receptor Agonists
Wallace, Grier A, Gordon, Thomas D, Hayes, Martin E, Konopacki, Donald B, Fix-Stenzel, Shannon R, Zhang, Xiaolei, Grongsaard, Pintipa, Cusack, Kevin P, Schaffter, Lisa M, Henry, Rodger F, Stoffel, Robert H
Published in Journal of organic chemistry (03.07.2009)
Published in Journal of organic chemistry (03.07.2009)
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Journal Article
Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H4 Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models
Cowart, Marlon D, Altenbach, Robert J, Liu, Huaqing, Hsieh, Gin C, Drizin, Irene, Milicic, Ivan, Miller, Thomas R, Witte, David G, Wishart, Neil, Fix-Stenzel, Shannon R, McPherson, Michael J, Adair, Ronald M, Wetter, Jill M, Bettencourt, Brian M, Marsh, Kennan C, Sullivan, James P, Honore, Prisca, Esbenshade, Timothy A, Brioni, Jorge D
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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Journal Article
Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H4 Receptor Ligands
Altenbach, Robert J, Adair, Ronald M, Bettencourt, Brian M, Black, Lawrence A, Fix-Stenzel, Shannon R, Gopalakrishnan, Sujatha M, Hsieh, Gin C, Liu, Huaqing, Marsh, Kennan C, McPherson, Michael J, Milicic, Ivan, Miller, Thomas R, Vortherms, Timothy A, Warrior, Usha, Wetter, Jill M, Wishart, Neil, Witte, David G, Honore, Prisca, Esbenshade, Timothy A, Hancock, Arthur A, Brioni, Jorge D, Cowart, Marlon D
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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Journal Article
A stereoselective and scalable synthesis of a conformationally constrained S1P1 agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (01.07.2009)
Published in Tetrahedron letters (01.07.2009)
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Journal Article
Rotationally Constrained 2,4-Diamino-5,6-disubstituted Pyrimidines: A New Class of Histamine H-4 Receptor Antagonists with Improved Druglikeness and in Vivo Efficacy in Pain and Inflammation Models
Cowart, Marlon D., Altenbach, Robert J., Liu, Huaqing, Hsieh, Gin C., Drizin, Irene, Milicic, Ivan, Miller, Thomas R., Witte, David G., Wishart, Neil, Fix-Stenzel, Shannon R., McPherson, Michael J., Adair, Ronald M., Wetter, Jill M., Bettencourt, Brian M., Marsh, Kerman C., Sullivan, James P., Honore, Prisca, Esbenshade, Timothy A., Brioni, Jorge D.
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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Journal Article
Structure-Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H-4 Receptor Ligands
Altenbach, Robert J., Adair, Ronald M., Bettencourt, Brian M., Black, Lawrence A., Fix-Stenzel, Shannon R., Gopalakrishnan, Suiatha M., Hsieh, Gin C., Liu, Huaqing, Marsh, Kennan C., McPherson, Michael J., Milicic, Ivan, Miller, Thomas R., Vortherms, Timothy A., Warrior, Usha, Wetter, Jill M., Wishart, Neil, Witte, David G., Honore, Prisca, Esbenshade, Timothy A., Hancock, Arthur A., Brioni, Jorge D., Cowart, Marlon D.
Published in Journal of medicinal chemistry (23.10.2008)
Published in Journal of medicinal chemistry (23.10.2008)
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Journal Article
A stereoselective and scalable synthesis of a conformationally constrained S1P(1) agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (15.07.2009)
Published in Tetrahedron letters (15.07.2009)
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Journal Article
A stereoselective and scalable synthesis of a conformationally constrained S1P 1 agonist
Fix-Stenzel, Shannon R., Hayes, Martin E., Zhang, Xiaolei, Wallace, Grier A., Grongsaard, Pintipa, Schaffter, Lisa M., Hannick, Steven M., Franczyk, Thaddeus S., Stoffel, Robert H., Cusack, Kevin P.
Published in Tetrahedron letters (2009)
Published in Tetrahedron letters (2009)
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Journal Article
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Year of Publication 04.09.2013
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Pyrrolopyridine and pyrrolopyrimidine inhibitors of kinases
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Year of Publication 08.04.2014
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NOVEL OXADIAZOLE COMPOUNDS
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Year of Publication 17.10.2012
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NOVEL OXADIAZOLE COMPOUNDS
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Year of Publication 16.06.2011
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NOVEL OXADIAZOLE COMPOUNDS
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PYRROLOPYRIDINE AND PYRROLOPYRIMIDINE INHIBITORS OF KINASES
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Year of Publication 17.11.2011
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Year of Publication 17.11.2011
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Novel Oxadiazole Compounds
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Year of Publication 25.08.2011
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Year of Publication 25.08.2011
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