Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma
Matschiner, Gabriele, Fitzgerald, Mary F., Moebius, Ulrich, Hohlbaum, Andreas M., Gille, Hendrik, Jensen, Kristian, Kirchfeld, Klaus, Rattenstetter, Barbara, Laforge, Alice, Bel Aiba, Rachida S., Ciccotosto, Joe, Nyugen, Hong, Foster, Martyn L., Snouwaert, John N., Nguyen, MyTrang, Koller, Beverly H., Matis, Louis, Anderson, Gary P., Olwill, Shane A.
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Published in Journal of allergy and clinical immunology (01.04.2023)
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Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction
Heinzelmann, Katharina, Fysikopoulos, Athanasios, Jaquin, Thomas J., Peper-Gabriel, Janet K., Hansbauer, Eva-Maria, Grüner, Stefan, Prassler, Josef, Wurzenberger, Claudia, Kennedy, Joseph G. C., Snead, Jazmin Y., Wrennall, Joe A., Heinig, Kristina, Wurzenberger, Cornelia, Bel Aiba, Rachida-Siham, Tarran, Robert, Livraghi-Butrico, Alessandra, Fitzgerald, Mary F., Anderson, Gary P., Rothe, Christine, Matschiner, Gabriele, Olwill, Shane A., Hagner, Matthias
Published in American journal of physiology. Lung cellular and molecular physiology (05.11.2024)
Published in American journal of physiology. Lung cellular and molecular physiology (05.11.2024)
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Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases
von Nussbaum, Franz, Li, Volkhart M. -J., Allerheiligen, Swen, Anlauf, Sonja, Baerfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F., Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schaefer, Martina, Schaefer, Stefan, Schamberger, Jens, Telan, Leila A., Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)
Published in ChemMedChem (01.07.2015)
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Journal Article
Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases
von Nussbaum, Franz, Li, Volkhart M.-J., Allerheiligen, Swen, Anlauf, Sonja, Bärfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F., Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schäfer, Martina, Schäfer, Stefan, Schamberger, Jens, Telan, Leila A., Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)
Published in ChemMedChem (01.07.2015)
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p38α-Selective Mitogen-Activated Protein Kinase Inhibitor SD-282 Reduces Inflammation in a Subchronic Model of Tobacco Smoke-Induced Airway Inflammation
Medicherla, Satyanarayana, Fitzgerald, Mary F., Spicer, Dianne, Woodman, Paul, Ma, Jing Y., Kapoun, Ann M., Chakravarty, Sarvajit, Dugar, Sundeep, Protter, Andrew A., Higgins, Linda S.
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
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Inhibition of antigen-induced contraction of guinea-pig airways by a leukotriene synthesis inhibitor, BAY x1005
Gardiner, Phillip J., Cuthbert, Nigel J., Francis, Hilary P., Fitzgerald, Mary F., Thompson, Angela M., Carpenter, Tracey G., Patel, Umesh P., Newton, Benjamin B., Mohrs, Klaus, Müller-Peddinghaus, Reiner, Taylor, William A.
Published in European journal of pharmacology (02.06.1994)
Published in European journal of pharmacology (02.06.1994)
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Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases (ChemMedChem 7/2015)
von Nussbaum, Franz, Li, Volkhart M.-J., Allerheiligen, Swen, Anlauf, Sonja, Bärfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F., Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schäfer, Martina, Schäfer, Stefan, Schamberger, Jens, Telan, Leila A., Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)
Published in ChemMedChem (01.07.2015)
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Journal Article
Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases
vonNussbaum, Franz, Li, Volkhart M-J, Allerheiligen, Swen, Anlauf, Sonja, Barfacker, Lars, Bechem, Martin, Delbeck, Martina, Fitzgerald, Mary F, Gerisch, Michael, Gielen-Haertwig, Heike, Haning, Helmut, Karthaus, Dagmar, Lang, Dieter, Lustig, Klemens, Meibom, Daniel, Mittendorf, Joachim, Rosentreter, Ulrich, Schafer, Martina, Schafer, Stefan, Schamberger, Jens, Telan, Leila A, Tersteegen, Adrian
Published in ChemMedChem (01.07.2015)
Published in ChemMedChem (01.07.2015)
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Journal Article
p38α-Selective Mitogen-Activated Protein Kinase Inhibitor SD-282 Reduces Inflammation in a Subchronic Model of Tobacco Smoke-Induced Airway Inflammation
Satyanarayana Medicherla, Mary F. Fitzgerald, Dianne Spicer, Paul Woodman, Jing Y. Ma, Ann M. Kapoun, Sarvajit Chakravarty, Sundeep Dugar, Andrew A. Protter, Linda S. Higgins
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
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Journal Article
p38alpha-selective mitogen-activated protein kinase inhibitor SD-282 reduces inflammation in a subchronic model of tobacco smoke-induced airway inflammation
Medicherla, Satyanarayana, Fitzgerald, Mary F, Spicer, Dianne, Woodman, Paul, Ma, Jing Y, Kapoun, Ann M, Chakravarty, Sarvajit, Dugar, Sundeep, Protter, Andrew A, Higgins, Linda S
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
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Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
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TUMOR NECROSIS FACTOR RECEPTOR 1 ANTAGONISTS FOR TREATING RESPIRATORY DISEASES
FITZGERALD, Mary, F, TOMLINSON, Ian, M, DE WILDT, Rudolf, M., T, FOX, Justian, Craig, HOLMES, Steve, LEE, Jennifer, WINTER, Gregory, P, SEPP, Armin, WOOLVEN, Benjamin, P
Year of Publication 25.07.2018
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Year of Publication 25.07.2018
Patent
METHODS FOR TARGETING PULMONARY DISEASES WITH AGENTS THAT BIND A TARGET IN PULMONARY TISSUE
Tomlinson Ian M, Fitzgerald Mary F, De Wildt Rudolf M. T, Fox Justian Craig, Luckett Jennifer, Sepp Armin, Woolven Benjamin P, Winter Gregory P, Holmes Steve
Year of Publication 27.07.2017
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Year of Publication 27.07.2017
Patent
Methods for targeting pulmonary diseases with agents that bind a target in pulmonary tissue
Tomlinson Ian M, Fitzgerald Mary F, De Wildt Rudolf M. T, Fox Justian Craig, Luckett Jennifer, Sepp Armin, Woolven Benjamin P, Winter Gregory P, Holmes Steve
Year of Publication 25.04.2017
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Year of Publication 25.04.2017
Patent
The anaphylactic release of platelet‐activating factor from perfused guinea‐pig lungs
Fitzgerald, Mary F., Moncada, Salvador, Parente, Luca
Published in British journal of pharmacology (01.05.1986)
Published in British journal of pharmacology (01.05.1986)
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