The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia
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Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6-dependent manner
Peña-Martínez, P, Eriksson, M, Ramakrishnan, R, Chapellier, M, Högberg, C, Orsmark-Pietras, C, Richter, J, Andersson, A, Fioretos, T, Järås, M
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Implementing precision medicine in a regionally organized healthcare system in Sweden
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Published in Nature medicine (2022)
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Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status
ANDERSSON, A, RITZ, C, BEHRENDTZ, M, HÖGLUND, M, JOHANSSON, B, FIORETOS, T, LINDGREN, D, EDEN, P, LASSEN, C, HELDRUP, J, OLOFSSON, T, RADE, J, FONTES, M, PORWIT-MACDONALD, A
Published in Leukemia (01.06.2007)
Published in Leukemia (01.06.2007)
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RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib
Lilljebjörn, H, Ågerstam, H, Orsmark-Pietras, C, Rissler, M, Ehrencrona, H, Nilsson, L, Richter, J, Fioretos, T
Published in Leukemia (01.04.2014)
Published in Leukemia (01.04.2014)
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Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
Mustjoki, S, Richter, J, Barbany, G, Ehrencrona, H, Fioretos, T, Gedde-Dahl, T, Gjertsen, B T, Hovland, R, Hernesniemi, S, Josefsen, D, Koskenvesa, P, Dybedal, I, Markevärn, B, Olofsson, T, Olsson-Strömberg, U, Rapakko, K, Thunberg, S, Stenke, L, Simonsson, B, Porkka, K, Hjorth-Hansen, H
Published in Leukemia (01.07.2013)
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IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome
Landberg, N, Hansen, N, Askmyr, M, Ågerstam, H, Lassen, C, Rissler, M, Hjorth-Hansen, H, Mustjoki, S, Järås, M, Richter, J, Fioretos, T
Published in Leukemia (01.01.2016)
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Feasibility to use whole-genome sequencing as a sole diagnostic method to detect genomic aberrations in pediatric B-cell acute lymphoblastic leukemia
Rezayee, Fatemah, Eisfeldt, Jesper, Skaftason, Aron, Öfverholm, Ingegerd, Sayyab, Shumaila, Syvänen, Ann Christine, Maqbool, Khurram, Lilljebjörn, Henrik, Johansson, Bertil, Olsson-Arvidsson, Linda, Pietras, Christina Orsmark, Staffas, Anna, Palmqvist, Lars, Fioretos, Thoas, Cavelier, Lucia, Fogelstrand, Linda, Nordlund, Jessica, Wirta, Valtteri, Rosenquist, Richard, Barbany, Gisela
Published in Frontiers in oncology (2023)
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Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q
LINDGREN, D, LIEDBERG, F, ANDERSSON, A, CHEBIL, G, GUDJONSSON, S, BORG, A, MANSSON, W, FIORETOS, T, HÖGLUND, M
Published in Oncogene (27.04.2006)
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Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations
Davidsson, J, Paulsson, K, Lindgren, D, Lilljebjörn, H, Chaplin, T, Forestier, E, Andersen, M K, Nordgren, A, Rosenquist, R, Fioretos, T, Young, B D, Johansson, B
Published in Leukemia (01.05.2010)
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Whole-exome sequencing of pediatric acute lymphoblastic leukemia
Lilljebjörn, H, Rissler, M, Lassen, C, Heldrup, J, Behrendtz, M, Mitelman, F, Johansson, B, Fioretos, T
Published in Leukemia (01.07.2012)
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High-resolution genome-wide array-based comparative genome hybridization reveals cryptic chromosome changes in AML and MDS cases with trisomy 8 as the sole cytogenetic aberration
PAULSSON, K, HEIDENBLAD, M, STRÖMBECK, B, STAAF, J, JÖNSSON, G, BORG, A, FIORETOS, T, JOHANSSON, B
Published in Leukemia (01.05.2006)
Published in Leukemia (01.05.2006)
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Molecular Signatures in Childhood Acute Leukemia and Their Correlations to Expression Patterns in Normal Hematopoietic Subpopulations
Anna Andersson, Tor Olofsson, David Lindgren, Nilsson, Björn, Cecilia Ritz, Patrik Edén, Carin Lassen, Johan Råde, Magnus Fontes, Helena Mörse, Jesper Heldrup, Mikael Behrendtz, Mitelman, Felix, Höglund, Mattias, Johansson, Bertil, Thoas Fioretos
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
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Gain-of-Function SAMD9L Mutations Cause a Syndrome of Cytopenia, Immunodeficiency, Myelodysplastic Syndrome and Neurological Symptoms
Tesi, B, Davidsson, J, Voss, M, Rahikkala, E, Holmes, T, Chiang, S, Komulainen-Ebrahim, J, Kokkonen, H, Bryder, D, Fioretos, T, Henter, J.I, Möttönen, M, Niinimäki, R, Nilsson, L, Pronk, C.J, Uusimaa, J, Moilanen, J, Tedgård, U, Cammenga, J, Bryceson, Y
Published in LEUKEMIA RESEARCH (2017)
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SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function
Hansen, N, Ågerstam, H, Wahlestedt, M, Landberg, N, Askmyr, M, Ehinger, M, Rissler, M, Lilljebjörn, H, Johnels, P, Ishiko, J, Melo, J V, Alexander, W S, Bryder, D, Järås, M, Fioretos, T
Published in Leukemia (01.01.2013)
Published in Leukemia (01.01.2013)
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BRAF mutations are very rare in B- and T-cell pediatric acute lymphoblastic leukemias
Davidsson, J, Lilljebjörn, H, Panagopoulos, I, Fioretos, T, Johansson, B
Published in Leukemia (01.08.2008)
Published in Leukemia (01.08.2008)
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Combined high-resolution array-based comparative genomic hybridization and expression profiling of ETV6/RUNX1-positive acute lymphoblastic leukemias reveal a high incidence of cryptic Xq duplications and identify several putative target genes within the commonly gained region
LILLJEBJÖRN, H, HEIDENBLAD, M, NILSSON, B, LASSEN, C, HORVAT, A, HELDRUP, J, BEHRENDTZ, M, JOHANSSON, B, ANDERSSON, A, FIORETOS, T
Published in Leukemia (01.10.2007)
Published in Leukemia (01.10.2007)
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Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR ABL1 mediates resistance to imatinib in human leukaemia cells
SVENSSON, E, VIDOVIC, K, LASSEN, C, RICHTER, J, OLOFSSON, T, FIORETOS, T, GULLBERG, U
Published in Leukemia (01.12.2007)
Published in Leukemia (01.12.2007)
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Modeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells
Askmyr, M, Ågerstam, H, Lilljebjörn, H, Hansen, N, Karlsson, C, von Palffy, S, Landberg, N, Högberg, C, Lassen, C, Rissler, M, Richter, J, Ehinger, M, Järås, M, Fioretos, T
Published in Blood cancer journal (New York) (12.12.2014)
Published in Blood cancer journal (New York) (12.12.2014)
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