In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images
Christiansen, Eric M., Yang, Samuel J., Ando, D. Michael, Javaherian, Ashkan, Skibinski, Gaia, Lipnick, Scott, Mount, Elliot, O’Neil, Alison, Shah, Kevan, Lee, Alicia K., Goyal, Piyush, Fedus, William, Poplin, Ryan, Esteva, Andre, Berndl, Marc, Rubin, Lee L., Nelson, Philip, Finkbeiner, Steven
Published in Cell (19.04.2018)
Published in Cell (19.04.2018)
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Journal Article
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
Barmada, Sami J, Serio, Andrea, Arjun, Arpana, Bilican, Bilada, Daub, Aaron, Ando, D Michael, Tsvetkov, Andrey, Pleiss, Michael, Li, Xingli, Peisach, Daniel, Shaw, Christopher, Chandran, Siddharthan, Finkbeiner, Steven
Published in Nature chemical biology (01.08.2014)
Published in Nature chemical biology (01.08.2014)
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Journal Article
Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
Fang, Mark Y., Markmiller, Sebastian, Vu, Anthony Q., Javaherian, Ashkan, Dowdle, William E., Jolivet, Philippe, Bushway, Paul J., Castello, Nicholas A., Baral, Ashmita, Chan, Michelle Y., Linsley, Jeremy W., Linsley, Drew, Mercola, Mark, Finkbeiner, Steven, Lecuyer, Eric, Lewcock, Joseph W., Yeo, Gene W.
Published in Neuron (Cambridge, Mass.) (04.09.2019)
Published in Neuron (Cambridge, Mass.) (04.09.2019)
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Journal Article
Assessing microscope image focus quality with deep learning
Yang, Samuel J, Berndl, Marc, Michael Ando, D, Barch, Mariya, Narayanaswamy, Arunachalam, Christiansen, Eric, Hoyer, Stephan, Roat, Chris, Hung, Jane, Rueden, Curtis T, Shankar, Asim, Finkbeiner, Steven, Nelson, Philip
Published in BMC bioinformatics (15.03.2018)
Published in BMC bioinformatics (15.03.2018)
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Journal Article
small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model
Tsvetkov, Andrey S, Miller, Jason, Arrasate, Montserrat, Wong, Jinny S, Pleiss, Michael A, Finkbeiner, Steven
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (28.09.2010)
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Journal Article
Potential function for the Huntingtin protein as a scaffold for selective autophagy
Ochaba, Joseph, Lukacsovich, Tamás, Csikos, George, Zheng, Shuqiu, Margulis, Julia, Salazar, Lisa, Mao, Kai, Lau, Alice L., Yeung, Sylvia Y., Humbert, Sandrine, Saudou, Frédéric, Klionsky, Daniel J., Finkbeiner, Steven, Zeitlin, Scott O., Marsh, J. Lawrence, Housman, David E., Thompson, Leslie M., Steffan, Joan S.
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2014)
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Journal Article
Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy
Serio, Andrea, Bilican, Bilada, Barmada, Sami J., Ando, Dale Michael, Zhao, Chen, Siller, Rick, Burr, Karen, Haghi, Ghazal, Story, David, Nishimura, Agnes Lumi, Carrasco, Monica A., Phatnani, Hemali P., Shum, Carole, Wilmut, Ian, Maniatis, Tom, Shaw, Christopher E., Finkbeiner, Steven, Chandran, Siddharthan
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (19.03.2013)
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Journal Article
ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects
Qiu, Haiyan, Lee, Sebum, Shang, Yulei, Wang, Wen-Yuan, Au, Kin Fai, Kamiya, Sherry, Barmada, Sami J, Finkbeiner, Steven, Lui, Hansen, Carlton, Caitlin E, Tang, Amy A, Oldham, Michael C, Wang, Hejia, Shorter, James, Filiano, Anthony J, Roberson, Erik D, Tourtellotte, Warren G, Chen, Bin, Tsai, Li-Huei, Huang, Eric J
Published in The Journal of clinical investigation (01.03.2014)
Published in The Journal of clinical investigation (01.03.2014)
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Journal Article
Generation of two human induced pluripotent stem cell lines from fibroblasts of unrelated Parkinson’s patients carrying the G2019S mutation in the LRRK2 gene (LCSBi005, LCSBi006)
Novak, Gabriela, Finkbeiner, Steven, Skibinski, Gaia, Skupin, Alexander
Published in Stem cell research (01.12.2021)
Published in Stem cell research (01.12.2021)
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Journal Article
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models
ARMAKOLA, Maria, HIGGINS, Matthew J, FARESE, Robert V, GITLER, Aaron D, FIGLEY, Matthew D, BARMADA, Sami J, SCARBOROUGH, Emily A, DIAZ, Zamia, XIAODONG FANG, SHORTER, James, KROGAN, Nevan J, FINKBEINER, Steven
Published in Nature genetics (01.12.2012)
Published in Nature genetics (01.12.2012)
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Journal Article
Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice
Gu, Xiaofeng, Greiner, Erin R., Mishra, Rakesh, Kodali, Ravindra, Osmand, Alex, Finkbeiner, Steven, Steffan, Joan S., Thompson, Leslie Michels, Wetzel, Ronald, Yang, X. William
Published in Neuron (Cambridge, Mass.) (24.12.2009)
Published in Neuron (Cambridge, Mass.) (24.12.2009)
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Journal Article
Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease
Palop, Jorge J., Chin, Jeannie, Roberson, Erik D., Wang, Jun, Thwin, Myo T., Bien-Ly, Nga, Yoo, Jong, Ho, Kaitlyn O., Yu, Gui-Qiu, Kreitzer, Anatol, Finkbeiner, Steven, Noebels, Jeffrey L., Mucke, Lennart
Published in Neuron (Cambridge, Mass.) (06.09.2007)
Published in Neuron (Cambridge, Mass.) (06.09.2007)
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Journal Article
Generation of two human induced pluripotent stem cell lines (iPSCs) with mutations of the α-synuclein (SNCA) gene associated with Parkinson’s disease; the A53T mutation (LCSBi003) and a triplication of the SNCA gene (LCSBi007)
Novak, Gabriela, Finkbeiner, Steven, Skibinski, Gaia, Skupin, Alexander
Published in Stem cell research (01.12.2021)
Published in Stem cell research (01.12.2021)
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Journal Article
Arc regulates spine morphology and maintains network stability in vivo
Peebles, Carol L., Yoo, Jong, Thwin, Myo T., Palop, Jorge J., Noebels, Jeffrey L., Finkbeiner, Steven, Snyder, Solomon H.
Published in Proceedings of the National Academy of Sciences - PNAS (19.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (19.10.2010)
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