A phase 2 study of an oral mTORC1/mTORC2 kinase inhibitor (CC-223) for non-pancreatic neuroendocrine tumors with or without carcinoid symptoms
Wolin, Edward, Mita, Alain, Mahipal, Amit, Meyer, Tim, Bendell, Johanna, Nemunaitis, John, Munster, Pam N, Paz-Ares, Luis, Filvaroff, Ellen H, Li, Shaoyi, Hege, Kristen, de Haan, Hans, Mita, Monica
Published in PloS one (17.09.2019)
Published in PloS one (17.09.2019)
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Journal Article
Clinical activity of CC‐90011, an oral, potent, and reversible LSD1 inhibitor, in advanced malignancies
Hollebecque, Antoine, Salvagni, Stefania, Plummer, Ruth, Niccoli, Patricia, Capdevila, Jaume, Curigliano, Giuseppe, Moreno, Victor, Braud, Filippo, Villambrosia, Sonia Gonzalez, Martin‐Romano, Patricia, Baudin, Eric, Arias, Marina, Alvaro, Juan, Parra‐Palau, Josep L., Sánchez‐Pérez, Tania, Aronchik, Ida, Filvaroff, Ellen H., Lamba, Manisha, Nikolova, Zariana, Bono, Johann S.
Published in Cancer (01.09.2022)
Published in Cancer (01.09.2022)
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Journal Article
Phase I Study of Lysine-Specific Demethylase 1 Inhibitor, CC-90011, in Patients with Advanced Solid Tumors and Relapsed/Refractory Non-Hodgkin Lymphoma
Hollebecque, Antoine, Salvagni, Stefania, Plummer, Ruth, Isambert, Nicolas, Niccoli, Patricia, Capdevila, Jaume, Curigliano, Giuseppe, Moreno, Victor, Martin-Romano, Patricia, Baudin, Eric, Arias, Marina, Mora, Sheila, de Alvaro, Juan, Di Martino, Jorge, Parra-Palau, Josep L, Sánchez-Pérez, Tania, Aronchik, Ida, Filvaroff, Ellen H, Lamba, Manisha, Nikolova, Zariana, de Bono, Johann S
Published in Clinical cancer research (15.01.2021)
Published in Clinical cancer research (15.01.2021)
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Efficacy of a Covalent ERK1/2 Inhibitor, CC-90003, in KRAS-Mutant Cancer Models Reveals Novel Mechanisms of Response and Resistance
Aronchik, Ida, Dai, Yumin, Labenski, Matt, Barnes, Carmen, Jones, Terri, Qiao, Lixin, Beebe, Lisa, Malek, Mehnaz, Elis, Winfried, Shi, Tao, Mavrommatis, Konstantinos, Bray, Gordon L, Filvaroff, Ellen H
Published in Molecular cancer research (01.02.2019)
Published in Molecular cancer research (01.02.2019)
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Journal Article
Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia
Thijssen, Rachel, ter Burg, Johanna, Garrick, Brett, van Bochove, Gregor G.W., Brown, Jennifer R., Fernandes, Stacey M., Rodríguez, María Solé, Michot, Jean-Marie, Hallek, Michael, Eichhorst, Barbara, Reinhardt, Hans Christian, Bendell, Johanna, Derks, Ingrid A.M., van Kampen, Roel J.W., Hege, Kristen, Kersten, Marie José, Trowe, Torsten, Filvaroff, Ellen H., Eldering, Eric, Kater, Arnon P.
Published in Blood (28.07.2016)
Published in Blood (28.07.2016)
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Shallow shotgun sequencing reduces technical variation in microbiome analysis
La Reau, Alex J, Strom, Noah B, Filvaroff, Ellen, Mavrommatis, Konstantinos, Ward, Tonya L, Knights, Dan
Published in Scientific reports (11.05.2023)
Published in Scientific reports (11.05.2023)
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Journal Article
First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy
Munster, Pamela, Mita, Monica, Mahipal, Amit, Nemunaitis, John, Massard, Christophe, Mikkelsen, Tom, Cruz, Cristina, Paz-Ares, Luis, Hidalgo, Manuel, Rathkopf, Dana, Blumenschein, Jr, George, Smith, David C, Eichhorst, Barbara, Cloughesy, Tim, Filvaroff, Ellen H, Li, Shaoyi, Raymon, Heather, de Haan, Hans, Hege, Kristen, Bendell, Johanna C
Published in Cancer management and research (01.12.2019)
Published in Cancer management and research (01.12.2019)
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Journal Article
Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis
Caunt, Maresa, Mak, Judy, Liang, Wei-Ching, Stawicki, Scott, Pan, Qi, Tong, Raymond K., Kowalski, Joe, Ho, Calvin, Reslan, Hani Bou, Ross, Jed, Berry, Leanne, Kasman, Ian, Zlot, Constance, Cheng, Zhiyong, Le Couter, Jennifer, Filvaroff, Ellen H., Plowman, Greg, Peale, Franklin, French, Dorothy, Carano, Richard, Koch, Alexander W., Wu, Yan, Watts, Ryan J., Tessier-Lavigne, Marc, Bagri, Anil
Published in Cancer cell (01.04.2008)
Published in Cancer cell (01.04.2008)
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Journal Article
BET inhibitor trotabresib in heavily pretreated patients with solid tumors and diffuse large B-cell lymphomas
Moreno, Victor, Vieito, Maria, Sepulveda, Juan Manuel, Galvao, Vladimir, Hernández-Guerrero, Tatiana, Doger, Bernard, Saavedra, Omar, Carlo-Stella, Carmelo, Michot, Jean-Marie, Italiano, Antoine, Magagnoli, Massimo, Carpio, Cecilia, Pinto, Antonio, Sarmiento, Rafael, Amoroso, Barbara, Aronchik, Ida, Filvaroff, Ellen, Hanna, Bishoy, Wei, Xin, Nikolova, Zariana, Braña, Irene
Published in Nature communications (13.03.2023)
Published in Nature communications (13.03.2023)
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Journal Article
Vascular Endothelial Growth Factor Stimulates Bone Repair by Promoting Angiogenesis and Bone Turnover
Street, John, Bao, Min, deGuzman, Leo, Bunting, Stuart, Peale, Franklin V., Ferrara, Napoleone, Steinmetz, Hope, Hoeffel, John, Cleland, Jeffrey L., Daugherty, Ann, van Bruggen, Nicholas, Redmond, H. Paul, Richard A. D. Carano, Filvaroff, Ellen H.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2002)
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Journal Article
Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1
Wu, Ai-Luen, Kolumam, Ganesh, Stawicki, Scott, Chen, Yongmei, Li, Jun, Zavala-Solorio, Jose, Phamluong, Khanhky, Feng, Bo, Li, Li, Marsters, Scot, Kates, Lance, van Bruggen, Nicholas, Leabman, Maya, Wong, Anne, West, David, Stern, Howard, Luis, Elizabeth, Kim, Hok Seon, Yansura, Daniel, Peterson, Andrew S, Filvaroff, Ellen, Wu, Yan, Sonoda, Junichiro
Published in Science translational medicine (14.12.2011)
Published in Science translational medicine (14.12.2011)
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SMG1, a nonsense‐mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma
Leeksma, Alexander C., Derks, Ingrid A. M., Garrick, Brett, Jongejan, Aldo, Colombo, Martino, Bloedjes, Timon, Trowe, Torsten, Leisten, Jim C., Howarth, Michelle, Malek, Mehnaz, Mortensen, Deborah S., Blease, Kate, Groza, Mathew C., Narla, Rama Krishna, Loos, Remco, Kersten, Marie‐José, Moerland, Perry D., Guikema, Jeroen E. J., Kater, Arnon P., Eldering, Eric, Filvaroff, Ellen H.
Published in Molecular oncology (01.02.2023)
Published in Molecular oncology (01.02.2023)
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Journal Article
TGF-β Regulates the Mechanical Properties and Composition of Bone Matrix
Guive Balooch, Mehdi Balooch, Nalla, Ravi K., Schilling, Stephen, Filvaroff, Ellen H., Grayson W. Marshall, Sally J. Marshall, Robert O. Ritchie, Derynck, Rik, Tamara Alliston
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (27.12.2005)
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Journal Article
Angiogenesis Is Required for Successful Bone Induction During Distraction Osteogenesis
Fang, Tony D, Salim, Ali, Xia, Wei, Nacamuli, Randall P, Guccione, Samira, Song, HanJoon M, Carano, Richard A, Filvaroff, Ellen H, Bednarski, Mark D, Giaccia, Amato J, Longaker, Michael T
Published in Journal of bone and mineral research (01.07.2005)
Published in Journal of bone and mineral research (01.07.2005)
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Journal Article
TWEAK Attenuates the Transition from Innate to Adaptive Immunity
Maecker, Heather, Varfolomeev, Eugene, Kischkel, Frank, Lawrence, David, LeBlanc, Heidi, Lee, Wyne, Hurst, Stephen, Danilenko, Dimitry, Li, Jun, Filvaroff, Ellen, Yang, Becky, Daniel, Dylan, Ashkenazi, Avi
Published in Cell (02.12.2005)
Published in Cell (02.12.2005)
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Journal Article
IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
Hymowitz, Sarah G., Filvaroff, Ellen H., Yin, JianPing, Lee, James, Cai, Liping, Risser, Philip, Maruoka, Miko, Mao, Weiguang, Foster, Jessica, Kelley, Robert F., Pan, Guohua, Gurney, Austin L., de Vos, Abraham M., Starovasnik, Melissa A.
Published in The EMBO journal (01.10.2001)
Published in The EMBO journal (01.10.2001)
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Loss of the Serine/Threonine Kinase Fused Results in Postnatal Growth Defects and Lethality Due to Progressive Hydrocephalus
Merchant, Mark, Evangelista, Marie, Luoh, Shiuh-Ming, Frantz, Gretchen D., Chalasani, Sreedevi, Carano, Richard A. D., van Hoy, Marjie, Ramirez, Julio, Ogasawara, Annie K., McFarland, Leanne M., Filvaroff, Ellen H., French, Dorothy M., de Sauvage, Frederic J.
Published in Molecular and Cellular Biology (01.08.2005)
Published in Molecular and Cellular Biology (01.08.2005)
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Journal Article
WISP-1 Is an Osteoblastic Regulator Expressed During Skeletal Development and Fracture Repair
French, Dorothy M., Kaul, Raji J., D'souza, Aloma L., Crowley, Craig W., Bao, Min, Frantz, Gretchen D., Filvaroff, Ellen H., Desnoyers, Luc
Published in The American journal of pathology (01.09.2004)
Published in The American journal of pathology (01.09.2004)
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