Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor
Goldkorn, Tzipora, Filosto, Simone, Chung, Samuel
Published in Antioxidants & redox signaling (20.11.2014)
Published in Antioxidants & redox signaling (20.11.2014)
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Journal Article
Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma
Locke, Frederick L., Miklos, David B., Jacobson, Caron A., Perales, Miguel-Angel, Kersten, Marie-José, Oluwole, Olalekan O., Ghobadi, Armin, Rapoport, Aaron P., McGuirk, Joseph, Pagel, John M., Muñoz, Javier, Farooq, Umar, van Meerten, Tom, Reagan, Patrick M., Sureda, Anna, Flinn, Ian W., Vandenberghe, Peter, Song, Kevin W., Dickinson, Michael, Minnema, Monique C., Riedell, Peter A., Leslie, Lori A., Chaganti, Sridhar, Yang, Yin, Filosto, Simone, Shah, Jina, Schupp, Marco, To, Christina, Cheng, Paul, Gordon, Leo I., Westin, Jason R.
Published in The New England journal of medicine (17.02.2022)
Published in The New England journal of medicine (17.02.2022)
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IL-4 drives exhaustion of CD8+ CART cells
Stewart, Carli M., Siegler, Elizabeth L., Sakemura, R. Leo, Cox, Michelle J., Huynh, Truc, Kimball, Brooke, Mai, Long, Can, Ismail, Manriquez Roman, Claudia, Yun, Kun, Sirpilla, Olivia, Girsch, James H., Ogbodo, Ekene, Mohammed Ismail, Wazim, Gaspar-Maia, Alexandre, Budka, Justin, Kim, Jenny, Scholler, Nathalie, Mattie, Mike, Filosto, Simone, Kenderian, Saad S.
Published in Nature communications (12.09.2024)
Published in Nature communications (12.09.2024)
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High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers
Anderhub, Simon J, Mak, Grace Wing-Yan, Gurden, Mark D, Faisal, Amir, Drosopoulos, Konstantinos, Walsh, Katie, Woodward, Hannah L, Innocenti, Paolo, Westwood, Isaac M, Naud, Sébastien, Hayes, Angela, Theofani, Efthymia, Filosto, Simone, Saville, Harry, Burke, Rosemary, van Montfort, Rob L M, Raynaud, Florence I, Blagg, Julian, Hoelder, Swen, Eccles, Suzanne A, Linardopoulos, Spiros
Published in Molecular cancer therapeutics (01.10.2019)
Published in Molecular cancer therapeutics (01.10.2019)
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Neutral Sphingomyelinase 2 (nSMase2) Is a Phosphoprotein Regulated by Calcineurin (PP2B)
Filosto, Simone, Fry, William, Knowlton, Anne A., Goldkorn, Tzipora
Published in The Journal of biological chemistry (02.04.2010)
Published in The Journal of biological chemistry (02.04.2010)
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Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation
Bratt, Jennifer M, Chang, Kevin Y, Rabowsky, Michelle, Franzi, Lisa M, Ott, Sean P, Filosto, Simone, Goldkorn, Tzipora, Arif, Muhammad, Last, Jerold A, Kenyon, Nicholas J, Zeki, Amir A
Published in The Journal of immunology (1950) (01.06.2018)
Published in The Journal of immunology (1950) (01.06.2018)
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Journal Article
EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerization
Filosto, Simone, Khan, Elaine M, Tognon, Emiliana, Becker, Cathleen, Ashfaq, Majid, Ravid, Tommer, Goldkorn, Tzipora
Published in PloS one (10.08.2011)
Published in PloS one (10.08.2011)
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Journal Article
Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy
DAVIS, Benjamin B, ZEKI, Amir A, BRATT, Jennifer M, LEI WANG, FILOSTO, Simone, WALBY, William F, KENYON, Nicholas J, GOLDKORN, Tzipora, SCHELEGLE, Edward S, PINKERTON, Kent E
Published in The European respiratory journal (01.08.2013)
Published in The European respiratory journal (01.08.2013)
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Journal Article
PB2346: ZUMA‐24: A PHASE 2, OPEN‐LABEL, MULTICENTER STUDY OF AXICABTAGENE CILOLEUCEL IN PATIENTS WITH RELAPSED/REFRACTORY LARGE B‐CELL LYMPHOMA GIVEN WITH CORTICOSTEROIDS IN THE OUTPATIENT SETTING
Leslie, Lori, Tees, Michael, Flinn, Ian W., Rodriguez, Tulio, Baird, John H., Deol, Abhinav, Mead, Monica, Bachier, Carlos, Rapoport, Aaron P., Mcclune, Brian, Hoda, Daanish, Perales, Miguel‐Angel, Zheng, Yan, Filosto, Simone, Davis1, Madison, Miao, Harry, Kim, Jenny J., Oluwole, Olalekan O.
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Journal Article
Cadmium induces an apoptotic response in sea urchin embryos
Agnello, Maria, Filosto, Simone, Scudiero, Rosaria, Rinaldi, Anna M., Roccheri, Maria C.
Published in Cell stress & chaperones (01.03.2007)
Published in Cell stress & chaperones (01.03.2007)
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Journal Article
Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma
Locke, Frederick L, Miklos, David B, Jacobson, Caron A, Perales, Miguel-Angel, Kersten, Marie-José, Oluwole, Olalekan O, Ghobadi, Armin, Rapoport, Aaron P, McGuirk, Joseph, Pagel, John M, Muñoz, Javier, Farooq, Umar, van Meerten, Tom, Reagan, Patrick M, Sureda, Anna, Flinn, Ian W, Vandenberghe, Peter, Song, Kevin W, Dickinson, Michael, Minnema, Monique C, Riedell, Peter A, Leslie, Lori A, Chaganti, Sridhar, Yang, Yin, Filosto, Simone, Shah, Jina, Schupp, Marco, To, Christina, Cheng, Paul, Gordon, Leo I, Westin, Jason R
Published in The New England journal of medicine (17.02.2022)
Published in The New England journal of medicine (17.02.2022)
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Journal Article
Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma
Westin, Jason R., Oluwole, Olalekan O., Kersten, Marie José, Miklos, David B., Perales, Miguel-Angel, Ghobadi, Armin, Rapoport, Aaron P., Sureda, Anna, Jacobson, Caron A., Farooq, Umar, van Meerten, Tom, Ulrickson, Matthew, Elsawy, Mahmoud, Leslie, Lori A., Chaganti, Sridhar, Dickinson, Michael, Dorritie, Kathleen, Reagan, Patrick M., McGuirk, Joseph, Song, Kevin W., Riedell, Peter A., Minnema, Monique C., Yang, Yin, Vardhanabhuti, Saran, Filosto, Simone, Cheng, Paul, Shahani, Shilpa A., Schupp, Marco, To, Christina, Locke, Frederick L.
Published in The New England journal of medicine (13.07.2023)
Published in The New England journal of medicine (13.07.2023)
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Journal Article
PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer
Brasó-Maristany, Fara, Filosto, Simone, Catchpole, Steven, Marlow, Rebecca, Quist, Jelmar, Francesch-Domenech, Erika, Plumb, Darren A, Zakka, Leila, Gazinska, Patrycja, Liccardi, Gianmaria, Meier, Pascal, Gris-Oliver, Albert, Cheang, Maggie Chon U, Perdrix-Rosell, Anna, Shafat, Manar, Noël, Elodie, Patel, Nirmesh, McEachern, Kristen, Scaltriti, Maurizio, Castel, Pau, Noor, Farzana, Buus, Richard, Mathew, Sumi, Watkins, Johnathan, Serra, Violeta, Marra, Pierfrancesco, Grigoriadis, Anita, Tutt, Andrew N
Published in Nature medicine (01.11.2016)
Published in Nature medicine (01.11.2016)
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Journal Article
Investigating the Influence of Covariates on Axicabtagene Ciloleucel (axi-cel) Kinetics in Patients with Non-Hodgkin’s Lymphoma
Chartier, Magali, Filosto, Simone, Peyret, Thomas, Chiney, Manoj, Milletti, Francesca, Budka, Justin, Ndi, Andre, Dong, Jinghui, Vardhanabhuti, Saran, Mao, Daqin, Duffull, Stephen, Dodds, Michael, Shen, Rhine
Published in Clinical pharmacokinetics (01.09.2024)
Published in Clinical pharmacokinetics (01.09.2024)
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Journal Article
Lung cancer and lung injury: the dual role of ceramide
Goldkorn, Tzipora, Chung, Samuel, Filosto, Simone
Published in Handbook of experimental pharmacology (2013)
Published in Handbook of experimental pharmacology (2013)
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