Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice
Garriga-Canut, Mireia, Agustín-Pavón, Carmen, Herrmann, Frank, Sánchez, Aurora, Dierssen, Mara, Fillat, Cristina, Isalan, Mark
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (06.11.2012)
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Journal Article
The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
Boni, Jacopo, Rubio-Perez, Carlota, López-Bigas, Nuria, Fillat, Cristina, de la Luna, Susana
Published in Cancers (29.07.2020)
Published in Cancers (29.07.2020)
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Journal Article
Diabetes Risk Gene and Wnt Effector Tcf7l2/TCF4 Controls Hepatic Response to Perinatal and Adult Metabolic Demand
Boj, Sylvia F., van Es, Johan H., Huch, Meritxell, Li, Vivian S.W., José, Anabel, Hatzis, Pantelis, Mokry, Michal, Haegebarth, Andrea, van den Born, Maaike, Chambon, Pierre, Voshol, Peter, Dor, Yuval, Cuppen, Edwin, Fillat, Cristina, Clevers, Hans
Published in Cell (21.12.2012)
Published in Cell (21.12.2012)
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Journal Article
Aronia Berry Extract Modulates MYD88/NF-kB/P-Glycoprotein Axis to Overcome Gemcitabine Resistance in Pancreatic Cancer
Li, Yuan, Xu, Caiming, Han, Haiyong, Pascual-Sabater, Silvia, Fillat, Cristina, Goel, Ajay
Published in Pharmaceuticals (Basel, Switzerland) (09.07.2024)
Published in Pharmaceuticals (Basel, Switzerland) (09.07.2024)
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Journal Article
Berberine Overcomes Gemcitabine-Associated Chemoresistance through Regulation of Rap1/PI3K-Akt Signaling in Pancreatic Ductal Adenocarcinoma
Okuno, Keisuke, Xu, Caiming, Pascual-Sabater, Silvia, Tokunaga, Masanori, Han, Haiyong, Fillat, Cristina, Kinugasa, Yusuke, Goel, Ajay
Published in Pharmaceuticals (Basel, Switzerland) (28.09.2022)
Published in Pharmaceuticals (Basel, Switzerland) (28.09.2022)
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Journal Article
Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma
Ikemori, Rafael, Gabasa, Marta, Duch, Paula, Vizoso, Miguel, Bragado, Paloma, Arshakyan, Marselina, Luis, Iuliana-Cristiana, Marín, Albert, Morán, Sebastian, Castro, Manuel, Fuster, Gemma, Gea-Sorli, Sabrina, Jauset, Toni, Soucek, Laura, Montuenga, Luis M, Esteller, Manel, Monsó, Eduard, Peinado, Victor Ivo, Gascon, Pere, Fillat, Cristina, Hilberg, Frank, Reguart, Noemí, Alcaraz, Jordi
Published in Cancer research (Chicago, Ill.) (15.01.2020)
Published in Cancer research (Chicago, Ill.) (15.01.2020)
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Journal Article
Codon Usage and Adenovirus Fitness: Implications for Vaccine Development
Giménez-Roig, Judit, Núñez-Manchón, Estela, Alemany, Ramon, Villanueva, Eneko, Fillat, Cristina
Published in Frontiers in microbiology (10.02.2021)
Published in Frontiers in microbiology (10.02.2021)
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Journal Article
Zeb1 in Stromal Myofibroblasts Promotes Kras -Driven Development of Pancreatic Cancer
Sangrador, Irene, Molero, Xavier, Campbell, Fiona, Franch-Expósito, Sebastià, Rovira-Rigau, Maria, Samper, Esther, Domínguez-Fraile, Manuel, Fillat, Cristina, Castells, Antoni, Vaquero, Eva C
Published in Cancer research (Chicago, Ill.) (15.05.2018)
Published in Cancer research (Chicago, Ill.) (15.05.2018)
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Journal Article
DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells
Rozen, Esteban J., Roewenstrunk, Julia, Barallobre, María José, Di Vona, Chiara, Jung, Carole, Figueiredo, Ana F., Luna, Jeroni, Fillat, Cristina, Arbonés, Maria L., Graupera, Mariona, Valverde, Miguel A., de la Luna, Susana
Published in Cell reports (Cambridge) (08.05.2018)
Published in Cell reports (Cambridge) (08.05.2018)
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Journal Article
Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
Raimondi, Giulia, Mato-Berciano, Ana, Pascual-Sabater, Silvia, Rovira-Rigau, Maria, Cuatrecasas, Miriam, Fondevila, Constantino, Sánchez-Cabús, Santiago, Begthel, Harry, Boj, Sylvia F., Clevers, Hans, Fillat, Cristina
Published in EBioMedicine (01.06.2020)
Published in EBioMedicine (01.06.2020)
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Journal Article
X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options
Albert, Michael H., Bittner, Tanja C., Nonoyama, Shigeaki, Notarangelo, Lucia Dora, Burns, Siobhan, Imai, Kohsuke, Espanol, Teresa, Fasth, Anders, Pellier, Isabelle, Strauss, Gabriele, Morio, Tomohiro, Gathmann, Benjamin, Noordzij, Jeroen G., Fillat, Cristina, Hoenig, Manfred, Nathrath, Michaela, Meindl, Alfons, Pagel, Philipp, Wintergerst, Uwe, Fischer, Alain, Thrasher, Adrian J., Belohradsky, Bernd H., Ochs, Hans D.
Published in Blood (22.04.2010)
Published in Blood (22.04.2010)
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Journal Article
Implications of MicroRNAs in Oncolytic Virotherapy
Bofill-De Ros, Xavier, Rovira-Rigau, Maria, Fillat, Cristina
Published in Frontiers in oncology (04.07.2017)
Published in Frontiers in oncology (04.07.2017)
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Journal Article
Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness
Farrera-Sal, Martí, de Sostoa, Jana, Nuñez-Manchón, Estela, Moreno, Rafael, Fillat, Cristina, Bazan-Peregrino, Miriam, Alemany, Ramon
Published in International journal of molecular sciences (21.07.2020)
Published in International journal of molecular sciences (21.07.2020)
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Journal Article
Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome
Altafaj, Xavier, Martín, Eduardo D, Ortiz-Abalia, Jon, Valderrama, Aitana, Lao-Peregrín, Cristina, Dierssen, Mara, Fillat, Cristina
Published in Neurobiology of disease (01.04.2013)
Published in Neurobiology of disease (01.04.2013)
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Journal Article
The Value of Mouse Models of Rare Diseases: A Spanish Experience
Murillo-Cuesta, Silvia, Artuch, Rafael, Asensio, Fernando, de la Villa, Pedro, Dierssen, Mara, Enríquez, Jose Antonio, Fillat, Cristina, Fourcade, Stéphane, Ibáñez, Borja, Montoliu, Lluis, Oliver, Eduardo, Pujol, Aurora, Salido, Eduardo, Vallejo, Mario, Varela-Nieto, Isabel
Published in Frontiers in genetics (14.10.2020)
Published in Frontiers in genetics (14.10.2020)
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Journal Article
Andrographis Reverses Gemcitabine Resistance through Regulation of ERBB3 and Calcium Signaling Pathway in Pancreatic Ductal Adenocarcinoma
Okuno, Keisuke, Xu, Caiming, Pascual-Sabater, Silvia, Tokunaga, Masanori, Takayama, Tetsuji, Han, Haiyong, Fillat, Cristina, Kinugasa, Yusuke, Goel, Ajay
Published in Biomedicines (03.01.2023)
Published in Biomedicines (03.01.2023)
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