Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug–Drug Interaction Risk Profile
Hao, Junliang, Beck, James, Zhou, Xin, Lackner, Gregory L, Johnston, Richard, Reinhard, Matt, Goldsmith, Paul, Hollinshead, Sean, Dehlinger, Veronique, Filla, Sandra A, Wang, Xu-shan, Richardson, Jeffery, Posada, Maria, Mohutsky, Mike, Schober, Doug, Katner, Jason S, Chen, Qi, Hu, Bingjie, Remick, David M, Coates, David A, Mathes, Brian M, Hawk, Mai K, Svensson, Kjell A, Hembre, Erik
Published in Journal of medicinal chemistry (10.03.2022)
Published in Journal of medicinal chemistry (10.03.2022)
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Discovery of (+)-N-(3-Aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a Kinesin Spindle Protein Inhibitor and Potential Anticancer Agent
Theoclitou, Maria-Elena, Aquila, Brian, Block, Michael H, Brassil, Patrick J, Castriotta, Lillian, Code, Erin, Collins, Michael P, Davies, Audrey M, Deegan, Tracy, Ezhuthachan, Jayachandran, Filla, Sandra, Freed, Ellen, Hu, Haiqing, Huszar, Dennis, Jayaraman, Muthusamy, Lawson, Deborah, Lewis, Paula M, Nadella, Murali V. P, Oza, Vibha, Padmanilayam, Maniyan, Pontz, Timothy, Ronco, Lucienne, Russell, Daniel, Whitston, David, Zheng, Xiaolan
Published in Journal of medicinal chemistry (13.10.2011)
Published in Journal of medicinal chemistry (13.10.2011)
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GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: In vitro profile and in vivo analgesic efficacy
Martinez-Perez, Jose A., Iyengar, Smriti, Shannon, Harlan E., Bleakman, David, Alt, Andrew, Clawson, David K., Arnold, Brian M., Bell, Michael G., Bleisch, Thomas J., Castaño, Ana M., Del Prado, Miriam, Dominguez, Esteban, Escribano, Ana M., Filla, Sandra A., Ho, Ken H., Hudziak, Kevin J., Jones, Carrie K., Mateo, Ana, Mathes, Brian M., Mattiuz, Edward L., Ogden, Ann Marie L., Simmons, Rosa Maria A., Stack, Douglas R., Stratford, Robert E., Winter, Mark A., Wu, Zhipei, Ornstein, Paul L.
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
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GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models
Martinez-Perez, Jose A., Iyengar, Smriti, Shannon, Harlan E., Bleakman, David, Alt, Andrew, Arnold, Brian M., Bell, Michael G., Bleisch, Thomas J., Castaño, Ana M., Del Prado, Miriam, Dominguez, Esteban, Escribano, Ana M., Filla, Sandra A., Ho, Ken H., Hudziak, Kevin J., Jones, Carrie K., Mateo, Ana, Mathes, Brian M., Mattiuz, Edward L., Ogden, Ann Marie L., Simmons, Rosa Maria A., Stack, Douglas R., Stratford, Robert E., Winter, Mark A., Wu, Zhipei, Ornstein, Paul L.
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
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Pharmacological Characterization of the Competitive GLUK5 Receptor Antagonist Decahydroisoquinoline LY466195 in Vitro and in Vivo
Weiss, Brianne, Alt, Andrew, Ogden, Ann Marie, Gates, Mary, Dieckman, Donna K, Clemens-Smith, Amy, Ho, Ken H, Jarvie, Keith, Rizkalla, Geihan, Wright, Rebecca A, Calligaro, David O, Schoepp, Darryle, Mattiuz, Edward L, Stratford, Robert E, Johnson, Bryan, Salhoff, Craig, Katofiasc, Mary, Phebus, Lee A, Schenck, Kathryn, Cohen, Marlene, Filla, Sandra A, Ornstein, Paul L, Johnson, Kirk W, Bleakman, David
Published in The Journal of pharmacology and experimental therapeutics (01.08.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2006)
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Discovery of a Potent, Dual Serotonin and Norepinephrine Reuptake Inhibitor
Dreyfus, Nicolas, Myers, Jason K, Badescu, Valentina O, de Frutos, Oscar, de la Puente, Maria Luz, Ding, Chunjin, Filla, Sandra A, Fynboe, Karsten, Gernert, Douglas L, Heinz, Beverly A, Hemrick-Luecke, Susan K, Johnson, Kirk W, Johnson, Michael P, López, Pilar, Love, Patrick L, Martin, Laura J, Masquelin, Thierry, McCoy, Michael J, Mendiola, Javier, Morrow, Denise, Muhlhauser, Mark, Pascual, Gustavo, Perun, Thomas J, Pfeifer, Lance A, Phebus, Lee A, Richards, Simon J, Rincón, Juan Antonio, Seest, Eric P, Shah, Jikesh, Shaojuan, Jia, Simmons, Rosa Maria A, Stephenson, Gregory A, Tromiczak, Eric G, Thompson, Linda K, Walter, Magnus W, Weber, Wayne W, Zarrinmayeh, Hamideh, Thomas, Craig E, Joshi, Elizabeth, Iyengar, Smriti, Johansson, Anette M
Published in ACS medicinal chemistry letters (13.06.2013)
Published in ACS medicinal chemistry letters (13.06.2013)
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Novel Potent 5-HT1F Receptor Agonists: Structure−Activity Studies of a Series of Substituted N-[3-(1-Methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides
Filla, Sandra A, Mathes, Brian M, Johnson, Kirk W, Phebus, Lee A, Cohen, Marlene L, Nelson, David L, Zgombick, John M, Erickson, Jon A, Schenck, Kathryn W, Wainscott, David B, Branchek, Theresa A, Schaus, John M
Published in Journal of medicinal chemistry (03.07.2003)
Published in Journal of medicinal chemistry (03.07.2003)
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Substituted furo[3,2-b]pyridines: novel bioisosteres of 5-HT1F receptor agonists
MATHES, Brian M, HUDZIAK, Kevin J, FILLA, Sandra A, SCHAUS, John M, XU, Yao-Chang, NELSON, David L, WAINSCOTT, David B, NUTTER, Suzanne E, GOUGH, Wendy H, BRANCHEK, Theresa A, ZGOMBICK, John M
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
Substituted furo[3,2- b]pyridines: novel bioisosteres of 5-HT 1F receptor agonists
Mathes, Brian M., Hudziak, Kevin J., Schaus, John M., Xu, Yao-Chang, Nelson, David L., Wainscott, David B., Nutter, Suzanne E., Gough, Wendy H., Branchek, Theresa A., Zgombick, John M., Filla, Sandra A.
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Journal Article
Process Change: Increasing Efficiency and Compliance in SCD Application in PACU
Edwards, Shandra, Edwards, Shandra, Holthaus, Janelle, Filla, Sandra
Published in Journal of perianesthesia nursing (01.08.2017)
Published in Journal of perianesthesia nursing (01.08.2017)
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Journal Article
Let’s Take a Closer Look: Reviewing Safety Events at Annual Skills Day
Holthaus, Janelle, Edwards, Shandra, Filla, Sandra, Davis, Gail
Published in Journal of perianesthesia nursing (01.08.2018)
Published in Journal of perianesthesia nursing (01.08.2018)
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Journal Article
On the Stereochemistry of Diaryl-Substituted Cyclohexanones Formed by Michael Reactions. Trans to Cis Isomerization of Their Ketals under Basic Conditions
Rowland, Alex T, Filla, Sandra A, Coutlangus, Marilyn L, Winemiller, Mark D, Chamberlin, Mark J, Czulada, Gary, Johnson, Steven D, Sabat, Michal
Published in Journal of organic chemistry (26.06.1998)
Published in Journal of organic chemistry (26.06.1998)
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Streamlining the Outpatient Recovery Process
L’Hommedieu, Elizabeth, Davis, Gail, Becker, Colleen M., Filla, Sandra
Published in Journal of perianesthesia nursing (01.08.2017)
Published in Journal of perianesthesia nursing (01.08.2017)
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Patient/Family Centered Care in Perioperative Services
Cooper, Amy, Filla, Sandra, Dunn, Karen, Davis, Gail, Becker, Colleen
Published in Journal of perianesthesia nursing (01.08.2017)
Published in Journal of perianesthesia nursing (01.08.2017)
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