JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin Expression
Furtado, Andrezza Bond Vieira, Gonçalves, Debora Farina, Hartmann, Diane Duarte, Courtes, Aline Alves, Cassol, Gustavo, Nunez-Figueredo, Yanier, Argolo, Deivison Silva, do Nascimento, Ravena Pereira, Costa, Silvia Lima, da Silva, Victor Diogenes Amaral, Royes, Luiz Fernando Freire, Soares, Félix Alexandre Antunes
Published in Molecular neurobiology (01.09.2021)
Published in Molecular neurobiology (01.09.2021)
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Journal Article
Rutin improves glutamate uptake and inhibits glutamate excitotoxicity in rat brain slices
Ferreira, Rafael S., Teles-Souza, Jéssica, dos Santos Souza, Cleide, Pereira, Érica P. L., de Araújo, Fillipe M., da Silva, Alessandra Bispo, Castro e Silva, Juliana H., Nonose, Yasmine, Núñez-Figueredo, Yanier, de Assis, Adriano M., Souza, Diogo O., Costa, Maria de Fátima D., Moreira, José Cláudio F., Costa, Silvia L., da Silva, Victor D. A.
Published in Molecular biology reports (01.02.2021)
Published in Molecular biology reports (01.02.2021)
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Journal Article
A Strong Protective Action of Guttiferone-A, a Naturally Occurring Prenylated Benzophenone, Against Iron-Induced Neuronal Cell Damage
Figueredo, Yanier Núñez, García-Pupo, Laura, Rubio, Osmany Cuesta, Hernández, René Delgado, Naal, Zeki, Curti, Carlos, Pardo Andreu, Gilberto L.
Published in Journal of Pharmacological Sciences (2011)
Published in Journal of Pharmacological Sciences (2011)
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Journal Article
Therapeutic potential of the novel hybrid molecule JM-20 against focal cortical ischemia in rats
Yanier Núñez Figueredo, Jeney Ramírez-Sanchez, Gisele Hansel, Gilberto L. Pardo-Andreu, Nelson Merino, Guillermo Aparicio, Rene Delgado-Hernández, Laura García-Pupo, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Diogo O. Souza
Published in Journal of pharmacy & pharmacognosy research (01.07.2016)
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Published in Journal of pharmacy & pharmacognosy research (01.07.2016)
Journal Article
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
Santos, Cleonice Creusa, Cardim-Pires, Thyago R., Shvachiy, Liana, Fonseca-Fonseca, Luis Arturo, Muñoz, Patricia, Almeida, Áurea Maria A. N., Costa, Ana Carla S., Teles-Souza, Jéssica, Ochoa-Rodríguez, Estael, de Fátima Dias Costa, Maria, Palhano, Fernando L., Segura-Aguilar, Juan, Barbosa, Deyse B., do Bomfim, Mayra R., dos Santos Junior, Manoelito C., Leite, Franco Henrique A., da Rocha Pita, Samuel Silva, Costa, Silvia Lima, Núñez-Figueredo, Yanier, Outeiro, Tiago Fleming, Foguel, Débora, Silva, Victor Diogenes Amaral
Published in Neurotoxicity research (01.12.2022)
Published in Neurotoxicity research (01.12.2022)
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Journal Article
Carcinogenic effect of human tumor-derived cell-free filtrates in nude mice
Berlanga-Acosta, Jorge, Arteaga-Hernandez, Ernesto, Garcia-Ojalvo, Ariana, Duvergel-Calderin, Dayanis, Rodriguez-Touseiro, Marisol, Lopez-Marin, Laura, Suarez-Alba, Jose, Fuentes-Morales, Dasha, Mendoza-Fuentes, Osmany, Fernández-Puentes, Sheyla, Nuñez-Figueredo, Yanier, Guillen-Nieto, Gerardo
Published in Frontiers in molecular biosciences (18.04.2024)
Published in Frontiers in molecular biosciences (18.04.2024)
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Journal Article
Characterization of the anxiolytic and sedative profile of JM-20: a novel benzodiazepine-dihydropyridine hybrid molecule
Figueredo, Yanier Nuñez, Rodríguez, Estael Ochoa, Reyes, Yamila Verdecia, Domínguez, Carmen Carrillo, Parra, Alicia Lagarto, Sánchez, Jeney Ramirez, Hernández, René Delgado, Verdecia, Marlene Porto, Pardo Andreu, Gilberto L
Published in Neurological research (New York) (01.10.2013)
Published in Neurological research (New York) (01.10.2013)
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Journal Article
KM-34, a Novel Antioxidant Compound, Protects against 6-Hydroxydopamine-Induced Mitochondrial Damage and Neurotoxicity
Fonseca-Fonseca, Luis Arturo, Nuñez-Figueredo, Yanier, Sánchez, Jeney Ramírez, Guerra, Maylin Wong, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Hernádez, René Delgado, Menezes-Filho, Noelio J., Costa, Teresa Cristina Silva, de Santana, Wagno Alcântara, Oliveira, Joana L., Segura-Aguilar, Juan, da Silva, Victor Diogenes Amaral, Costa, Silva Lima
Published in Neurotoxicity research (01.08.2019)
Published in Neurotoxicity research (01.08.2019)
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Journal Article
In Vitro Neuroprotective and Anti-Inflammatory Activities of Natural and Semi-Synthetic Spirosteroid Analogues
García-Pupo, Laura, Zaldo-Castro, Armando, Exarchou, Vassiliki, Tacoronte-Morales, Juan Enrique, Pieters, Luc, Vanden Berghe, Wim, Nuñez-Figueredo, Yanier, Delgado-Hernández, René
Published in Molecules (Basel, Switzerland) (01.08.2016)
Published in Molecules (Basel, Switzerland) (01.08.2016)
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Journal Article
Antioxidant and neuroprotective effects of gossypitrin, a flavonoid from Talipariti elatum, against chemical hypoxia-induced PC12 cell death
María A. Bécquer-Viart, José González-Yaque, Luis A. Fonseca-Fonseca, Yanier Núñez-Figueredo, Gilberto L. Pardo Andreu
Published in Journal of pharmacy & pharmacognosy research (01.04.2018)
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Published in Journal of pharmacy & pharmacognosy research (01.04.2018)
Journal Article
Correlational assessment of the effects of JM-20 in a rat model of parkinsonism
Fonseca-Fonseca, Luis Arturo, Fuentes, Nancy Pavón, Sánchez, Jeney Ramírez, Iglesias, Ángela Tuero, Outeiro, Tiago Fleming, Silva, Víctor Diogenes Amaral da, Costa, Silvia Lima, Núñez-Figueredo, Yanier
Published in Behavioural brain research (05.01.2025)
Published in Behavioural brain research (05.01.2025)
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Journal Article
JM-20 potently prevents the onset of caffeine-induced anxiogenic phenotypes in zebrafish (Danio rerio)
dos Santos, Matheus Mülling, Ferreira, Sabrina Antunes, de Macedo, Gabriel Teixeira, Claro, Mariana Torri, Müller, Talise Ellwanger, Prestes, Alessandro de Souza, da Rocha, João Batista Teixeira, Núñez-Figueredo, Yanier, Barbosa, Nilda de Vargas
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.03.2024)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01.03.2024)
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Journal Article
Investigation of the cytotoxicity, genotoxicity and antioxidant prospects of JM-20 on human blood cells: A multi-target compound with potential therapeutic applications
Silva, Fernanda D'Avila da, Galiciolli, Maria Eduarda de Andrade, Irioda, Ana Carolina, Oliveira, Cláudia Sirlene, Piccoli, Bruna Candia, Prestes, Alessandro de Souza, Borin, Bruna Cogo, Schuch, Andre Passaglia, Ochoa-Rodríguez, Estael, Nuñez-Figueredo, Yanier, Rocha, João Batista Teixeira da
Published in Blood cells, molecules, & diseases (01.05.2024)
Published in Blood cells, molecules, & diseases (01.05.2024)
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Journal Article
JM-20 affects GABA neurotransmission in Caenorhabditis elegans
da Silva, Aline Franzen, Cordeiro, Larissa Marafiga, Soares, Marcell Vallandro, Zamberlan, Danielle Coradini, Baptista, Fabiane Bicca Obetine, da Silveira, Tássia Limana, Machado, Marina Lopes, Arantes, Leticia Priscilla, Nuñez-Figueredo, Yanier, Rodríguez, Estael Ochoa, Soares, Félix Alexandre Antunes
Published in Neurotoxicology (Park Forest South) (01.12.2022)
Published in Neurotoxicology (Park Forest South) (01.12.2022)
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Journal Article
Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources
D’Avila da Silva, Fernanda, Nogara, Pablo Andrei, Ochoa-Rodríguez, Estael, Nuñez-Figueredo, Yanier, Wong-Guerra, Maylin, Rosemberg, Denis Broock, Rocha, João Batista Teixeira da
Published in Biochimie (01.01.2020)
Published in Biochimie (01.01.2020)
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Journal Article
JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease
Fonseca-Fonseca, Luis Arturo, Wong-Guerra, Maylin, Ramírez-Sánchez, Jeney, Montano-Peguero, Yanay, Padrón Yaquis, Alejandro Saúl, Rodríguez, Abel Mondelo, da Silva, Víctor Diógenes Amaral, Costa, Silvia Lima, Pardo-Andreu, Gilberto L., Núñez-Figueredo, Yanier
Published in Neuroscience letters (18.01.2019)
Published in Neuroscience letters (18.01.2019)
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Journal Article
JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain
Ramírez-Sánchez, Jeney, Pires, Elisa Nicoloso Simões, Meneghetti, André, Hansel, Gisele, Nuñez-Figueredo, Yanier, Pardo-Andreu, Gilberto L., Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, Delgado-Hernández, René, Salbego, Christianne, Souza, Diogo O
Published in Molecular neurobiology (2019)
Published in Molecular neurobiology (2019)
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Journal Article
JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties
Fonseca-Fonseca, Luis Arturo, da Silva, Víctor Diogenes Amaral, Wong-Guerra, Maylin, Ramírez-Sánchez, Jeney, Yaquis, Alejandro Saúl Padrón, Ochoa-Rodríguez, Estael, Verdecia-Reyes, Yamila, de Araújo, Fillipe Mendes, Santana, Rejane Conceição, Outeiro, Tiago Fleming, Costa, Silvia Lima, Núñez-Figueredo, Yanier
Published in Neurotoxicology (Park Forest South) (01.01.2021)
Published in Neurotoxicology (Park Forest South) (01.01.2021)
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Journal Article
JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats
Wong-Guerra, Maylin, Montano-Peguero, Yanay, Ramírez-Sánchez, Jeney, Jiménez-Martin, Javier, Fonseca-Fonseca, Luis Arturo, Hernández-Enseñat, Daniela, Nonose, Yasmine, Valdés, Odalys, Mondelo-Rodriguez, Abel, Ortiz-Miranda, Yaquelin, Bergado, Gretchen, Carmenate, Tania, Soto del Valle, Roberto Menéndez, Pardo-Andreu, Gilberto, Outeiro, Tiago Fleming, Padrón-Yaquis, Alejandro Saúl, Martimbianco de Assis, Adriano, O Souza, Diogo, Nuñez-Figueredo, Yanier
Published in Neurotoxicology (Park Forest South) (01.12.2021)
Published in Neurotoxicology (Park Forest South) (01.12.2021)
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Journal Article