Tumor-on-a-chip platform to investigate progression and drug sensitivity in cell lines and patient-derived organoids
Shirure, Venktesh S, Bi, Ye, Curtis, Matthew B, Lezia, Andrew, Goedegebuure, Madeleine M, Goedegebuure, S Peter, Aft, Rebecca, Fields, Ryan C, George, Steven C
Published in Lab on a chip (07.12.2018)
Published in Lab on a chip (07.12.2018)
Get full text
Journal Article
Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
Hegde, Samarth, Krisnawan, Varintra E., Herzog, Brett H., Zuo, Chong, Breden, Marcus A., Knolhoff, Brett L., Hogg, Graham D., Tang, Jack P., Baer, John M., Mpoy, Cedric, Lee, Kyung Bae, Alexander, Katherine A., Rogers, Buck E., Murphy, Kenneth M., Hawkins, William G., Fields, Ryan C., DeSelm, Carl J., Schwarz, Julie K., DeNardo, David G.
Published in Cancer cell (16.03.2020)
Published in Cancer cell (16.03.2020)
Get full text
Journal Article
Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
Nywening, Timothy M, MD, Wang-Gillam, Andrea, MD, Sanford, Dominic E, MD, Belt, Brian A, MA, Panni, Roheena Z, MD, Cusworth, Brian M, BA, Toriola, Adetunji T, MD, Nieman, Rebecca K, MS, Worley, Lori A, BS, Yano, Motoyo, MD, Fowler, Kathryn J, MD, Lockhart, A Craig, MD, Suresh, Rama, MD, Tan, Benjamin R, MD, Lim, Kian-Huat, MD, Fields, Ryan C, MD, Strasberg, Steven M, Prof, Hawkins, William G, Prof, DeNardo, David G, PhD, Goedegebuure, S Peter, PhD, Linehan, David C, Dr Prof
Published in The lancet oncology (01.05.2016)
Published in The lancet oncology (01.05.2016)
Get full text
Journal Article
Metabolic syndrome, metabolic comorbid conditions and risk of early-onset colorectal cancer
Chen, Hanyu, Zheng, Xiaobin, Zong, Xiaoyu, Li, Zitong, Li, Na, Hur, Jinhee, Fritz, Cassandra DL, Chapman Jr, William, Nickel, Katelin B, Tipping, Andrew, Colditz, Graham A, Giovannucci, Edward L, Olsen, Margaret A, Fields, Ryan C, Cao, Yin
Published in Gut (01.06.2021)
Published in Gut (01.06.2021)
Get full text
Journal Article
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
Zhu, Yu, Herndon, John M., Sojka, Dorothy K., Kim, Ki-Wook, Knolhoff, Brett L., Zuo, Chong, Cullinan, Darren R., Luo, Jingqin, Bearden, Audrey R., Lavine, Kory J., Yokoyama, Wayne M., Hawkins, William G., Fields, Ryan C., Randolph, Gwendalyn J., DeNardo, David G.
Published in Immunity (Cambridge, Mass.) (15.08.2017)
Published in Immunity (Cambridge, Mass.) (15.08.2017)
Get full text
Journal Article
Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
Nywening, Timothy M, Belt, Brian A, Cullinan, Darren R, Panni, Roheena Z, Han, Booyeon J, Sanford, Dominic E, Jacobs, Ryan C, Ye, Jian, Patel, Ankit A, Gillanders, William E, Fields, Ryan C, DeNardo, David G, Hawkins, William G, Goedegebuure, Peter, Linehan, David C
Published in Gut (01.06.2018)
Published in Gut (01.06.2018)
Get full text
Journal Article
Rates and Patterns of Recurrence after Curative Intent Resection for Gastric Cancer: A United States Multi-Institutional Analysis
Spolverato, Gaya, MD, Ejaz, Aslam, MD, MPH, Kim, Yuhree, MD, MPH, Squires, Malcolm H., MD, Poultsides, George A., MD, FACS, Fields, Ryan C., MD, FACS, Schmidt, Carl, MD, FACS, Weber, Sharon M., MD, FACS, Votanopoulos, Konstantinos, MD, FACS, Maithel, Shishir K., MD, FACS, Pawlik, Timothy M., MD, MPH, PhD, FACS
Published in Journal of the American College of Surgeons (01.10.2014)
Published in Journal of the American College of Surgeons (01.10.2014)
Get full text
Journal Article
Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs)
Hashim, Yassar M, Trinkaus, Kathryn M, Linehan, David C, Strasberg, Steven S, Fields, Ryan C, Cao, Dengfeng, Hawkins, William G
Published in Annals of surgery (01.02.2014)
Published in Annals of surgery (01.02.2014)
Get more information
Journal Article
sc2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data
Feng, Jiarui, Goedegebuure, S Peter, Zeng, Amanda, Bi, Ye, Wang, Ting, Payne, Philip, Ding, Li, DeNardo, David, Hawkins, William, Fields, Ryan C, Li, Fuhai
Published in PLoS computational biology (05.01.2024)
Published in PLoS computational biology (05.01.2024)
Get full text
Journal Article
Breast and pancreatic cancer interrupt IRF8-dependent dendritic cell development to overcome immune surveillance
Meyer, Melissa A., Baer, John M., Knolhoff, Brett L., Nywening, Timothy M., Panni, Roheena Z., Su, Xinming, Weilbaecher, Katherine N., Hawkins, William G., Ma, Cynthia, Fields, Ryan C., Linehan, David C., Challen, Grant A., Faccio, Roberta, Aft, Rebecca L., DeNardo, David G.
Published in Nature communications (28.03.2018)
Published in Nature communications (28.03.2018)
Get full text
Journal Article
Agonism of CD11b reprograms innate immunity to sensitize pancreatic cancer to immunotherapies
Panni, Roheena Z, Herndon, John M, Zuo, Chong, Hegde, Samarth, Hogg, Graham D, Knolhoff, Brett L, Breden, Marcus A, Li, Xiaobo, Krisnawan, Varintra E, Khan, Samia Q, Schwarz, Julie K, Rogers, Buck E, Fields, Ryan C, Hawkins, William G, Gupta, Vineet, DeNardo, David G
Published in Science translational medicine (03.07.2019)
Published in Science translational medicine (03.07.2019)
Get more information
Journal Article
Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion
Jiang, Hong, Liu, Xiuting, Knolhoff, Brett L, Hegde, Samarth, Lee, Kyung Bae, Jiang, Hongmei, Fields, Ryan C, Pachter, Jonathan A, Lim, Kian-Huat, DeNardo, David G
Published in Gut (01.01.2020)
Published in Gut (01.01.2020)
Get full text
Journal Article
Multidisciplinary Care of BRAF‐Mutant Stage III Melanoma: A Physicians Perspective Review
Cornelius, Lynn A., Fields, Ryan C., Tarhini, Ahmad
Published in The oncologist (Dayton, Ohio) (01.09.2021)
Published in The oncologist (Dayton, Ohio) (01.09.2021)
Get full text
Journal Article
Tumor-on-chip modeling of organ-specific cancer and metastasis
Del Piccolo, Nuala, Shirure, Venktesh S., Bi, Ye, Goedegebuure, S. Peter, Gholami, Sepideh, Hughes, Christopher C.W., Fields, Ryan C., George, Steven C.
Published in Advanced drug delivery reviews (01.08.2021)
Published in Advanced drug delivery reviews (01.08.2021)
Get full text
Journal Article
Biomarker-Driven Prognostication in Merkel Cell Carcinoma: A Paradigm for Personalized Therapy
Helmink, Beth A., Ansstas, George, Fields, Ryan C.
Published in Annals of surgical oncology (01.03.2022)
Published in Annals of surgical oncology (01.03.2022)
Get full text
Journal Article
Comments on “Challenging Orthodoxy: Beyond the Critical View of Safety”
Strasberg, Steven M., Brunt, L. Michael, Fields, Ryan C., Alseidi, Adnan, Hawkins, William G.
Published in Journal of gastrointestinal surgery (01.06.2023)
Published in Journal of gastrointestinal surgery (01.06.2023)
Get full text
Journal Article
Ablative Five-Fraction Stereotactic Body Radiation Therapy for Inoperable Pancreatic Cancer Using Online MR-Guided Adaptation
Hassanzadeh, Comron, Rudra, Soumon, Bommireddy, Ani, Hawkins, William G., Wang-Gillam, Andrea, Fields, Ryan C., Cai, Bin, Park, Justin, Green, Olga, Roach, Michael, Henke, Lauren, Kim, Hyun
Published in Advances in radiation oncology (01.01.2021)
Published in Advances in radiation oncology (01.01.2021)
Get full text
Journal Article