Three-Dimensional Cell Culture Assays: Are They More Predictive of In Vivo Efficacy than 2D Monolayer Cell-Based Assays?
Sittampalam, Sitta, Eglen, Richard, Ferguson, Stephen, Maynes, Jason Thomas, Olden, Kenneth, Schrader, Laura, Shelper, Todd, Ferrer, Marc
Published in Assay and drug development technologies (01.06.2015)
Published in Assay and drug development technologies (01.06.2015)
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Allosteric Inhibitors of the Eya2 Phosphatase Are Selective and Inhibit Eya2-mediated Cell Migration
Krueger, Aaron B., Drasin, David J., Lea, Wendy A., Patrick, Aaron N., Patnaik, Samarjit, Backos, Donald S., Matheson, Christopher J., Hu, Xin, Barnaeva, Elena, Holliday, Michael J., Blevins, Melanie A., Robin, Tyler P., Eisenmesser, Elan Z., Ferrer, Marc, Simeonov, Anton, Southall, Noel, Reigan, Philip, Marugan, Juan, Ford, Heide L., Zhao, Rui
Published in The Journal of biological chemistry (06.06.2014)
Published in The Journal of biological chemistry (06.06.2014)
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High throughput screening to assess urothelial cancer lines and their metastatic derivatives for assessing changes in sensitivity in therapeutics
Krane, Louis Spencer, Railkar, Reema, Hsu, Iawan, Vocke, Cathy, Meltzer, Paul S., Thomas, Craig, Ferrer, Marc, Agarwal, Piyush K.
Published in Journal of clinical oncology (10.01.2016)
Published in Journal of clinical oncology (10.01.2016)
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A 3D Heterotypic Multicellular Tumor Spheroid Assay Platform to Discriminate Drug Effects on Stroma versus Cancer Cells
Weydert, Zoe, Lal-Nag, Madhu, Mathews-Greiner, Lesley, Thiel, Christoph, Cordes, Henrik, Küpfer, Lars, Guye, Patrick, Kelm, Jens M., Ferrer, Marc
Published in SLAS discovery (01.03.2020)
Published in SLAS discovery (01.03.2020)
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Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition
Estrada, Lisbell D, Chamorro, David, Yañez, María José, Gonzalez, Marcelo, Leal, Nancy, von Bernhardi, Rommy, Dulcey, Andrés E, Marugan, Juan, Ferrer, Marc, Soto, Claudio, Zanlungo, Silvana, Inestrosa, Nibaldo C, Alvarez, Alejandra R
Published in Journal of Alzheimer's disease (04.10.2016)
Published in Journal of Alzheimer's disease (04.10.2016)
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Acute-phase dynamics and prognostic value of growth differentiation factor-15 in ST-elevation myocardial infarction
Rueda, Ferran, Lupón, Josep, García-García, Cosme, Cediel, German, Aranda Nevado, M. Cruz, Serra Gregori, Judith, Labata, Carlos, Oliveras, Teresa, Ferrer, Marc, de Diego, Oriol, Serra, Jordi, Revuelta López, Elena, Bayés-Genís, Antoni
Published in Clinical chemistry and laboratory medicine (01.07.2019)
Published in Clinical chemistry and laboratory medicine (01.07.2019)
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Debris-flow forecasting at regional scale by combining susceptibility mapping and radar rainfall
Berenguer, M, Sempere-Torres, D, Hürlimann, M
Published in Natural hazards and earth system sciences (13.03.2015)
Published in Natural hazards and earth system sciences (13.03.2015)
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Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile
Wilson, Kenneth J., Xiao, Jingbo, Chen, Catherine Z., Huang, Zaohua, Agoulnik, Irina U., Ferrer, Marc, Southall, Noel, Hu, Xin, Zheng, Wei, Xu, Xin, Wang, Amy, Myhr, Courtney, Barnaeva, Elena, George, Emmett R., Agoulnik, Alexander I., Marugan, Juan J.
Published in European journal of medicinal chemistry (05.08.2018)
Published in European journal of medicinal chemistry (05.08.2018)
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Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models
Yu, Lu, Zhang, Xiaoli, Yang, Yexin, Li, Dan, Tang, Kaiyuan, Zhao, Zifan, He, Wanwan, Wang, Ce, Sahoo, Nirakar, Converso-Baran, Kimber, Davis, Carol S, Brooks, Susan V, Bigot, Anne, Calvo, Raul, Martinez, Natalia J, Southall, Noel, Hu, Xin, Marugan, Juan, Ferrer, Marc, Xu, Haoxing
Published in Science advances (07.02.2020)
Published in Science advances (07.02.2020)
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Diagnostic cutoff values of synovial fluid biomarkers for acute postoperative prosthetic joint infection: a systematic review and meta-analysis
Sabater-Martos, Marta, Ferrer, Marc, Morata, Laura, Soriano, Alex, Martínez-Pastor, Juan Carlos
Published in Journal of bone and joint infection (29.01.2024)
Published in Journal of bone and joint infection (29.01.2024)
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A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth
Lal-Nag, Madhu, McGee, Lauren, Guha, Rajarshi, Lengyel, Ernst, Kenny, Hilary A., Ferrer, Marc
Published in SLAS discovery (01.06.2017)
Published in SLAS discovery (01.06.2017)
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Ten-year prognosis of acute atrial fibrillation in ST-elevation myocardial infarction: recurrence and risk stroke
Martínez Membrive, María José, Subirana, Isaac, Fadeuilhe, Edgar, Rueda, Ferran, Carreras-Mora, José, Oliveras, Teresa, Giralt, Teresa, Labata, Carlos, Ferrer, Marc, El Ouaddi, Nabil, Montero, Santiago, Elosúa, Roberto, Ribas, Núria, Bayés-Genís, Antoni, García-García, Cosme
Published in European heart journal. Acute cardiovascular care (03.06.2024)
Published in European heart journal. Acute cardiovascular care (03.06.2024)
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A modified gene trap approach for improved high-throughput cancer drug discovery
Morris, Shelli M., Mhyre, Andrew J., Carmack, Savanna S., Myers, Carrie H., Burns, Connor, Ye, Wenjuan, Ferrer, Marc, Olson, James M., Klinghoffer, Richard A.
Published in Oncogene (01.08.2018)
Published in Oncogene (01.08.2018)
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Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer
Vilimas, Tomas, Wang, Amy Q., Patnaik, Samarjit, Hughes, Emma A., Singleton, Marc D., Knotts, Zachary, Li, Dandan, Frankowski, Kevin, Schlomer, Jerome J., Guerin, Theresa M., Springer, Stephanie, Drennan, Catherine, Dextras, Christopher, Wang, Chen, Gilbert, Debra, Southall, Noel, Ferrer, Marc, Huang, Sui, Kozlov, Serguei, Marugan, Juan, Xu, Xin, Rudloff, Udo
Published in Cancer chemotherapy and pharmacology (01.12.2018)
Published in Cancer chemotherapy and pharmacology (01.12.2018)
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Inflammatory biotype of ADHD is linked to chronic stress: a data-driven analysis of the inflammatory proteome
Schnorr, Isabel, Siegl, Anne, Luckhardt, Sonja, Wenz, Söri, Friedrichsen, Hendrik, El Jomaa, Hiba, Steinmann, Annebirth, Kilencz, Tünde, Arteaga-Henríquez, Gara, Ramos-Sayalero, Carolina, Ibanez-Jimenez, Pol, Rosales-Ortiz, Silvia Karina, Bitter, István, Fadeuilhe, Christian, Ferrer, Marc, Lavebratt, Catharina, Réthelyi, János M., Richarte, Vanesa, Rommelse, Nanda, Ramos-Quiroga, Josep Antoni, Arias-Vasquez, Alejandro, Resch, Eduard, Reif, Andreas, Matura, Silke, Schiweck, Carmen
Published in Translational psychiatry (18.01.2024)
Published in Translational psychiatry (18.01.2024)
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Comorbid attention-deficit/hyperactivity disorder in borderline patients defines an impulsive subtype of borderline personality disorder
Ferrer, Marc, Andión, Oscar, Matalí, Josep, Valero, Sergi, Navarro, José Antonio, Ramos-Quiroga, Josep Antoni, Torrubia, Rafael, Casas, Miguel
Published in Journal of personality disorders (01.12.2010)
Published in Journal of personality disorders (01.12.2010)
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Target deconvolution of a multikinase inhibitor with anti-metastatic properties identifies TAOK3 as a key contributor to a cancer stem cell-like phenotype
Bian, Yansong, Teper, Yaroslav, Griner, Lesley A. Mathews, Aiken, Taylor J., Shukla, Vivek, Guha, Rajarshi, Shinn, Paul, Xin, Hong-Wu, Pflicke, Holger, Powers, Astin S., Li, Dandan, Jiang, Jian-kang, Patel, Paresma, Rogers, Steven A., Aubé, Jeffrey, Ferrer, Marc, Thomas, Craig J, Rudloff, Udo
Published in Molecular cancer therapeutics (08.08.2019)
Published in Molecular cancer therapeutics (08.08.2019)
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New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening
Major, Michael B, Roberts, Brian S, Berndt, Jason D, Marine, Shane, Anastas, Jamie, Chung, Namjin, Ferrer, Marc, Yi, XianHua, Stoick-Cooper, Cristi L, von Haller, Priska D, Kategaya, Lorna, Chien, Andy, Angers, Stephane, MacCoss, Michael, Cleary, Michele A, Arthur, William T, Moon, Randall T
Published in Science signaling (11.11.2008)
Published in Science signaling (11.11.2008)
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SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy
Sarathy, Apurva, Wuebbles, Ryan D., Fontelonga, Tatiana M., Tarchione, Ashley R., Mathews Griner, Lesley A., Heredia, Dante J., Nunes, Andreia M., Duan, Suzann, Brewer, Paul D., Van Ry, Tyler, Hennig, Grant W., Gould, Thomas W., Dulcey, Andrés E., Wang, Amy, Xu, Xin, Chen, Catherine Z., Hu, Xin, Zheng, Wei, Southall, Noel, Ferrer, Marc, Marugan, Juan, Burkin, Dean J.
Published in Molecular therapy (07.06.2017)
Published in Molecular therapy (07.06.2017)
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