Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes
Sutton, Jon M., Clark, David E., Dunsdon, Stephen J., Fenton, Garry, Fillmore, Amanda, Harris, Neil V., Higgs, Chris, Hurley, Chris A., Krintel, Sussie L., MacKenzie, Robert E., Duttaroy, Alokesh, Gangl, Eric, Maniara, Wiesia, Sedrani, Richard, Namoto, Kenji, Ostermann, Nils, Gerhartz, Bernd, Sirockin, Finton, Trappe, Jörg, Hassiepen, Ulrich, Baeschlin, Daniel K.
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
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Discovery of C-(1-aryl-cyclohexyl)-methylamines as selective, orally available inhibitors of dipeptidyl peptidase IV
Namoto, Kenji, Sirockin, Finton, Ostermann, Nils, Gessier, Francois, Flohr, Stefanie, Sedrani, Richard, Gerhartz, Bernd, Trappe, Jörg, Hassiepen, Ulrich, Duttaroy, Alokesh, Ferreira, Suzie, Sutton, Jon M., Clark, David E., Fenton, Garry, Beswick, Mandy, Baeschlin, Daniel K.
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
Published in Bioorganic & medicinal chemistry letters (01.02.2014)
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Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Syntheses and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogs
Ashton, Michael J, Cook, David C, Fenton, Garry, Karlsson, Jan-Anders, Palfreyman, Malcolm N, Raeburn, David, Ratcliffe, Andrew J, Souness, John E, Thurairatnam, Suga, Vicker, Nigel
Published in Journal of medicinal chemistry (01.05.1994)
Published in Journal of medicinal chemistry (01.05.1994)
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IODOETHERIFICATION OF HOMOALLYLIC ALCOHOLS - A STEREOSELECTIVE APPROACH TO TETRAHYDROFURANS
BEDFORD, SB, BELL, KE, FENTON, G, HAYES, CJ, KNIGHT, DW, SHAW, D
Published in Tetrahedron letters (20.10.1992)
Published in Tetrahedron letters (20.10.1992)
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Erratum to “Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes” [Bioorg. Med. Chem. Lett. 22 (2012) 1464–1468]
Sutton, Jon M., Clark, David E., Dunsdon, Stephen J., Fenton, Garry, Fillmore, Amanda, Harris, Neil V., Higgs, Chris, Hurley, Chris A., Krintel, Sussie L., MacKenzie, Robert E., Duttaroy, Alokesh, Gangl, Eric, Maniara, Wiesia, Sedrani, Richard, Namoto, Kenji, Ostermann, Nils, Gerhartz, Bernd, Sirockin, Finton, Trappe, Jörg, Hassiepen, Ulrich, Baeschlin, Daniel K.
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
Published in Bioorganic & medicinal chemistry letters (15.03.2012)
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The asymmetric synthesis of beta-haloaryl-beta-amino acid derivatives
Bull, SD, Davies, SG, Delgado-Ballester, S, Fenton, G, Kelly, PM, Smith, AD
Published in Synlett (2000)
Published in Synlett (2000)
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Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase
Levell, Julian, Astles, Peter, Eastwood, Paul, Cairns, Jennifer, Houille, Olivier, Aldous, Suzanne, Merriman, Gregory, Whiteley, Brian, Pribish, James, Czekaj, Mark, Liang, Guyan, Maignan, Sebastien, Guilloteau, Jean-Pierre, Dupuy, Alain, Davidson, Jane, Harrison, Trevor, Morley, Andrew, Watson, Simon, Fenton, Garry, McCarthy, Clive, Romano, Joseph, Mathew, Rose, Engers, Darren, Gardyan, Michael, Sides, Keith, Kwong, Jennifer, Tsay, Joseph, Rebello, Sam, Shen, Liduo, Wang, Jie, Luo, Yongyi, Giardino, Odessa, Lim, Heng-Keang, Smith, Keith, Pauls, Henry
Published in Bioorganic & medicinal chemistry (15.04.2005)
Published in Bioorganic & medicinal chemistry (15.04.2005)
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Mapping the kinase domain of janus kinase 3
Adams, Christopher, Aldous, David J., Amendola, Shelley, Bamborough, Paul, Bright, Colin, Crowe, Sarah, Eastwood, Paul, Fenton, Garry, Foster, Martyn, Harrison, Trevor K.P., King, Sue, Lai, Justine, Lawrence, Christopher, Letallec, Jean-Philippe, McCarthy, Clive, Moorcroft, Neil, Page, Kenneth, Rao, Sudha, Redford, Jane, Sadiq, Shazia, Smith, Keith, Souness, John E., Thurairatnam, Sukanthini, Vine, Mark, Wyman, Barry
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
Published in Bioorganic & medicinal chemistry letters (15.09.2003)
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1-AMINOMETHYL-L-PHENYL-CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS
FLOHR STEFANIE, FENTON GARRY, BESWIK MANDY CHRISTINE, SIROCKIN FINTON, NAMOTO KENJI, BAESCHLIN DANIEL KASPAR, SEDRANI RICHARD, GESSIER FRANCOIS, CLARK DAVID EDWARD, WASZKOWYCZ BOHDAN
Year of Publication 11.09.2009
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Year of Publication 11.09.2009
Patent
Hypolipidemic 2-[4-(1,1-dimethylethyl)phenyl]-4H-3,1-benzoxazin-4-ones. Structure-activity relationships of a novel series of high-density lipoprotein elevators
Fenton, Garry, Newton, Christopher G, Wyman, Barry M, Bagge, Philip, Dron, Donald I, Riddell, David, Jones, Graham D
Published in Journal of medicinal chemistry (01.01.1989)
Published in Journal of medicinal chemistry (01.01.1989)
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Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of betaII tryptase
Levell, Julian, Astles, Peter, Eastwood, Paul, Cairns, Jennifer, Houille, Olivier, Aldous, Suzanne, Merriman, Gregory, Whiteley, Brian, Pribish, James, Czekaj, Mark, Liang, Guyan, Maignan, Sebastien, Guilloteau, Jean-Pierre, Dupuy, Alain, Davidson, Jane, Harrison, Trevor, Morley, Andrew, Watson, Simon, Fenton, Garry, McCarthy, Clive, Romano, Joseph, Mathew, Rose, Engers, Darren, Gardyan, Michael, Sides, Keith, Kwong, Jennifer, Tsay, Joseph, Rebello, Sam, Shen, Liduo, Wang, Jie, Luo, Yongyi, Giardino, Odessa, Lim, Heng-Keang, Smith, Keith, Pauls, Henry
Published in Bioorganic & medicinal chemistry (15.04.2005)
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Published in Bioorganic & medicinal chemistry (15.04.2005)
Journal Article
Mapping the kinase domain of Janus Kinase 3: Recent advances in the design of kinase inhibitors as novel therapeutic agents
ADAMS, Christopher, ALDOUS, David J, KING, Sue, LAI, Justine, LAWRENCE, Christopher, LETALLEC, Jean-Philippe, MCCARTHY, Clive, MOORCROFT, Neil, PAGE, Kenneth, RAO, Sudha, REDFORD, Jane, SADIQ, Shazia, AMENDOLA, Shelley, SMITH, Keith, SOUNESS, John E, THURAIRATNAM, Sukanthini, VINE, Mark, WYMAN, Barry, BAMBOROUGH, Paul, BRIGHT, Colin, CROWE, Sarah, EASTWOOD, Paul, FENTON, Garry, FOSTER, Martyn, HARRISON, Trevor K. P
Published in Bioorganic & medicinal chemistry letters (2003)
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Published in Bioorganic & medicinal chemistry letters (2003)
Journal Article
PROCESS FOR PREPARATION OF INDOLE DERIVATIVES
FENTON, GARRY, RIDDELL, DAVID, ASHTON, MICHAEL JOHN, CHAPMAN, ROBERT FREDERICK, LOVELESS, ANTHONY H, BRIDGE, ANDREW WILLIAM
Year of Publication 10.10.1985
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Year of Publication 10.10.1985
Patent