Structure of the human marker of self 5-transmembrane receptor CD47
Fenalti, Gustavo, Villanueva, Nicolas, Griffith, Mark, Pagarigan, Barbra, Lakkaraju, Sirish Kaushik, Huang, Richard Y.-C., Ladygina, Nadia, Sharma, Alok, Mikolon, David, Abbasian, Mahan, Johnson, Jeffrey, Hadjivassiliou, Haralambos, Zhu, Dan, Chamberlain, Philip P., Cho, Ho, Hariharan, Kandasamy
Published in Nature communications (01.09.2021)
Published in Nature communications (01.09.2021)
Get full text
Journal Article
Structure of the CCR5 Chemokine Receptor—HIV Entry Inhibitor Maraviroc Complex
Tan, Qiuxiang, Zhu, Ya, Li, Jian, Chen, Zhuxi, Han, Gye Won, Kufareva, Irina, Li, Tingting, Ma, Limin, Fenalti, Gustavo, Li, Jing, Zhang, Wenru, Xie, Xin, Yang, Huaiyu, Jiang, Hualiang, Cherezov, Vadim, Liu, Hong, Stevens, Raymond C., Zhao, Qiang, Wu, Beili
Published in Science (American Association for the Advancement of Science) (20.09.2013)
Published in Science (American Association for the Advancement of Science) (20.09.2013)
Get full text
Journal Article
GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
Pike, Robert N, Rosado, Carlos J, Fenalti, Gustavo, Mahmood, Khalid, El-Kabbani, Ossama, Wilce, Matthew, Tuck, Kellie, Rossjohn, Jamie, Mackay, Ian R, Whisstock, James C, Schmidberger, Jason, Rowley, Merrill J, Banga, J Paul, Faux, Noel G, Smith, A Ian, Hampe, Christiane S, Langendorf, Christopher, Law, Ruby H P, Buckle, Ashley M
Published in Nature structural & molecular biology (01.04.2007)
Published in Nature structural & molecular biology (01.04.2007)
Get full text
Journal Article
The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions
Langendorf, Christopher G, Key, Trevor L G, Fenalti, Gustavo, Kan, Wan-Ting, Buckle, Ashley M, Caradoc-Davies, Tom, Tuck, Kellie L, Law, Ruby H P, Whisstock, James C
Published in PloS one (18.02.2010)
Published in PloS one (18.02.2010)
Get full text
Journal Article
COOH-Terminal Clustering of Autoantibody and T-Cell Determinants on the Structure of GAD65 Provide Insights Into the Molecular Basis of Autoreactivity
FENALTI, Gustavo, HAMPE, Christiane S, ARAFAT, Yasir, LAW, Ruby H. P, BANGA, J. Paul, MACKAY, Ian R, WHISSTOCK, James C, BUCKLE, Ashley M, ROWLEY, Merrill J
Published in Diabetes (New York, N.Y.) (01.05.2008)
Published in Diabetes (New York, N.Y.) (01.05.2008)
Get full text
Journal Article
Allosteric sodium in class A GPCR signaling
Katritch, Vsevolod, Fenalti, Gustavo, Abola, Enrique E., Roth, Bryan L., Cherezov, Vadim, Stevens, Raymond C.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2014)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2014)
Get full text
Journal Article
Conserved Binding Mode of Human β2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
Wacker, Daniel, Fenalti, Gustavo, Brown, Monica A., Katritch, Vsevolod, Abagyan, Ruben, Cherezov, Vadim, Stevens, Raymond C.
Published in Journal of the American Chemical Society (25.08.2010)
Published in Journal of the American Chemical Society (25.08.2010)
Get full text
Journal Article
Molecular control of δ-opioid receptor signalling
Fenalti, Gustavo, Giguere, Patrick M., Katritch, Vsevolod, Huang, Xi-Ping, Thompson, Aaron A., Cherezov, Vadim, Roth, Bryan L., Stevens, Raymond C.
Published in Nature (London) (13.02.2014)
Published in Nature (London) (13.02.2014)
Get full text
Journal Article
Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine
Qin, Ling, Kufareva, Irina, Holden, Lauren G., Wang, Chong, Zheng, Yi, Zhao, Chunxia, Fenalti, Gustavo, Wu, Huixian, Han, Gye Won, Cherezov, Vadim, Abagyan, Ruben, Stevens, Raymond C., Handel, Tracy M.
Published in Science (American Association for the Advancement of Science) (06.03.2015)
Published in Science (American Association for the Advancement of Science) (06.03.2015)
Get full text
Journal Article
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
Zhang, Kaihua, Zhang, Jin, Gao, Zhan-Guo, Zhang, Dandan, Zhu, Lan, Han, Gye Won, Moss, Steven M., Paoletta, Silvia, Kiselev, Evgeny, Lu, Weizhen, Fenalti, Gustavo, Zhang, Wenru, Müller, Christa E., Yang, Huaiyu, Jiang, Hualiang, Cherezov, Vadim, Katritch, Vsevolod, Jacobson, Kenneth A., Stevens, Raymond C., Wu, Beili, Zhao, Qiang
Published in Nature (London) (01.05.2014)
Published in Nature (London) (01.05.2014)
Get full text
Journal Article
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
Wu, Beili, Chien, Ellen Y.T, Mol, Clifford D, Fenalti, Gustavo, Liu, Wei, Katritch, Vsevolod, Abagyan, Ruben, Brooun, Alexei, Wells, Peter, Bi, F. Christopher, Hamel, Damon J, Kuhn, Peter, Handel, Tracy M, Cherezov, Vadim, Stevens, Raymond C
Published in Science (American Association for the Advancement of Science) (19.11.2010)
Published in Science (American Association for the Advancement of Science) (19.11.2010)
Get full text
Journal Article
Discovery and Preclinical Characterization of CC-95251, an Anti-SIRPα Antibody That Enhances Macrophage-Mediated Phagocytosis of Non-Hodgkin Lymphoma (NHL) Cells When Combined with Rituximab
Chan, Henry, Trout, Christina, Mikolon, David, Adams, Preston, Guzman, Roberto, Fenalti, Gustavo, Mavrommatis, Konstantinos, Abbasian, Mahan, Dearth, Lawrence, Fox, Brian, Sivakumar, Pallavur, Hariharan, Kandasamy
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
Get full text
Journal Article
Structural basis for bifunctional peptide recognition at human δ-opioid receptor
Fenalti, Gustavo, Zatsepin, Nadia A, Betti, Cecilia, Giguere, Patrick, Han, Gye Won, Ishchenko, Andrii, Liu, Wei, Guillemyn, Karel, Zhang, Haitao, James, Daniel, Wang, Dingjie, Weierstall, Uwe, Spence, John C H, Boutet, Sébastien, Messerschmidt, Marc, Williams, Garth J, Gati, Cornelius, Yefanov, Oleksandr M, White, Thomas A, Oberthuer, Dominik, Metz, Markus, Yoon, Chun Hong, Barty, Anton, Chapman, Henry N, Basu, Shibom, Coe, Jesse, Conrad, Chelsie E, Fromme, Raimund, Fromme, Petra, Tourwé, Dirk, Schiller, Peter W, Roth, Bryan L, Ballet, Steven, Katritch, Vsevolod, Stevens, Raymond C, Cherezov, Vadim
Published in Nature structural & molecular biology (01.03.2015)
Published in Nature structural & molecular biology (01.03.2015)
Get full text
Journal Article
Design and Optimization Leading to an Orally Active TTK Protein Kinase Inhibitor with Robust Single Agent Efficacy
Riggs, Jennifer R, Elsner, Jan, Cashion, Dan, Robinson, Dale, Tehrani, Lida, Nagy, Mark, Fultz, Kimberly E, Krishna Narla, Rama, Peng, Xiaohui, Tran, Tam, Kulkarni, Ashutosh, Bahmanyar, Sogole, Condroski, Kevin, Pagarigan, Barbra, Fenalti, Gustavo, LeBrun, Laurie, Leftheris, Katerina, Zhu, Dan, Boylan, John F
Published in Journal of medicinal chemistry (09.05.2019)
Published in Journal of medicinal chemistry (09.05.2019)
Get full text
Journal Article
Molecular control of [delta]-opioid receptor signalling
Fenalti, Gustavo, Giguere, Patrick M, Katritch, Vsevolod, Huang, Xi-Ping, Thompson, Aaron A, Cherezov, Vadim, Roth, Bryan L, Stevens, Raymond C
Published in Nature (London) (13.02.2014)
Published in Nature (London) (13.02.2014)
Get full text
Journal Article
Molecular control of δ-opioid receptor signalling
Fenalti, Gustavo, Giguere, Patrick M, Katritch, Vsevolod, Huang, Xi- Ping, Thompson, Aaron A, Cherezov, Vadim, Roth, Bryan L, Stevens, Raymond C
Published in Nature (London) (13.02.2014)
Published in Nature (London) (13.02.2014)
Get full text
Journal Article