Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes
Walsh, Roddy, Buchan, Rachel, Wilk, Alicja, John, Shibu, Felkin, Leanne E, Thomson, Kate L, Chiaw, Tang Hak, Loong, Calvin Chin Woon, Pua, Chee Jian, Raphael, Claire, Prasad, Sanjay, Barton, Paul J, Funke, Birgit, Watkins, Hugh, Ware, James S, Cook, Stuart A
Published in European heart journal (07.12.2017)
Published in European heart journal (07.12.2017)
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Journal Article
Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy
Mazzarotto, Francesco, Tayal, Upasana, Buchan, Rachel J, Midwinter, William, Wilk, Alicja, Whiffin, Nicola, Govind, Risha, Mazaika, Erica, de Marvao, Antonio, Dawes, Timothy J.W, Felkin, Leanne E, Ahmad, Mian, Theotokis, Pantazis I, Edwards, Elizabeth, Ing, Alexander Y, Thomson, Kate L, Chan, Laura L.H, Sim, David, Baksi, A John, Pantazis, Antonis, Roberts, Angharad M, Watkins, Hugh, Funke, Birgit, O’Regan, Declan P, Olivotto, Iacopo, Barton, Paul J.R, Prasad, Sanjay K, Cook, Stuart A, Ware, James S, Walsh, Roddy
Published in Circulation (New York, N.Y.) (04.02.2020)
Published in Circulation (New York, N.Y.) (04.02.2020)
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Journal Article
Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins
Chothani, Sonia, Schäfer, Sebastian, Adami, Eleonora, Viswanathan, Sivakumar, Widjaja, Anissa A, Langley, Sarah R, Tan, Jessie, Wang, Mao, Quaife, Nicholas M, Jian Pua, Chee, D’Agostino, Giuseppe, Guna Shekeran, Shamini, George, Benjamin L, Lim, Stella, Yiqun Cao, Elaine, van Heesch, Sebastiaan, Witte, Franziska, Felkin, Leanne E, Christodoulou, Eleni G, Dong, Jinrui, Blachut, Susanne, Patone, Giannino, Barton, Paul J.R, Hubner, Norbert, Cook, Stuart A, Rackham, Owen J.L
Published in Circulation (New York, N.Y.) (10.09.2019)
Published in Circulation (New York, N.Y.) (10.09.2019)
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Journal Article
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury
Widjaja, Anissa A, Dong, Jinrui, Adami, Eleonora, Viswanathan, Sivakumar, Ng, Benjamin, Pakkiri, Leroy S, Chothani, Sonia P, Singh, Brijesh K, Lim, Wei Wen, Zhou, Jin, Shekeran, Shamini G, Tan, Jessie, Lim, Sze Yun, Goh, Joyce, Wang, Mao, Holgate, Robert, Hearn, Arron, Felkin, Leanne E, Yen, Paul M, Dear, James W, Drum, Chester L, Schafer, Sebastian, Cook, Stuart A
Published in Science translational medicine (09.06.2021)
Published in Science translational medicine (09.06.2021)
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WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling
Chen, Huimei, Moreno-Moral, Aida, Pesce, Francesco, Devapragash, Nithya, Mancini, Massimiliano, Heng, Ee Ling, Rotival, Maxime, Srivastava, Prashant K, Harmston, Nathan, Shkura, Kirill, Rackham, Owen J L, Yu, Wei-Ping, Sun, Xi-Ming, Tee, Nicole Gui Zhen, Tan, Elisabeth Li Sa, Barton, Paul J R, Felkin, Leanne E, Lara-Pezzi, Enrique, Angelini, Gianni, Beltrami, Cristina, Pravenec, Michal, Schafer, Sebastian, Bottolo, Leonardo, Hubner, Norbert, Emanueli, Costanza, Cook, Stuart A, Petretto, Enrico
Published in Nature communications (09.08.2019)
Published in Nature communications (09.08.2019)
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Journal Article
The Calcineurin Variant CnAβ1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation
Gómez-Salinero, Jesús M., López-Olañeta, Marina M., Ortiz-Sánchez, Paula, Larrasa-Alonso, Javier, Gatto, Alberto, Felkin, Leanne E., Barton, Paul J.R., Navarro-Lérida, Inmaculada, del Pozo, Miguel Ángel, García-Pavía, Pablo, Sundararaman, Balaji, Giovinazo, Giovanna, Yeo, Gene W., Lara-Pezzi, Enrique
Published in Cell chemical biology (17.11.2016)
Published in Cell chemical biology (17.11.2016)
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Journal Article
Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling
Chen, Huimei, Moreno-Moral, Aida, Pesce, Francesco, Devapragash, Nithya, Mancini, Massimiliano, Heng, Ee Ling, Rotival, Maxime, Srivastava, Prashant K, Harmston, Nathan, Shkura, Kirill, Rackham, Owen J L, Yu, Wei-Ping, Sun, Xi-Ming, Tee, Nicole Gui Zhen, Tan, Elisabeth Li Sa, Barton, Paul J R, Felkin, Leanne E, Lara-Pezzi, Enrique, Angelini, Gianni, Beltrami, Cristina, Pravenec, Michal, Schafer, Sebastian, Bottolo, Leonardo, Hubner, Norbert, Emanueli, Costanza, Cook, Stuart A, Petretto, Enrico
Published in Nature communications (09.09.2019)
Published in Nature communications (09.09.2019)
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Journal Article
Expression of Follistatin-Related Genes Is Altered in Heart Failure
Lara-Pezzi, Enrique, Felkin, Leanne E, Birks, Emma J, Sarathchandra, Padmini, Panse, Kalyani D, George, Robert, Hall, Jennifer L, Yacoub, Magdi H, Rosenthal, Nadia, Barton, Paul J. R
Published in Endocrinology (Philadelphia) (01.11.2008)
Published in Endocrinology (Philadelphia) (01.11.2008)
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Journal Article
Calcineurin Splicing Variant Calcineurin Aβ1 Improves Cardiac Function After Myocardial Infarction Without Inducing Hypertrophy
FELKIN, Leanne E, NARITA, Takuya, ROSENTHAL, Nadia, LARA-PEZZI, Enrique, GERMACK, Renee, SHINTANI, Yasunori, TAKAHASHI, Kunihiko, SARATHCHANDRA, Padmini, LOPEZ-OLANETA, Marina M, GOMEZ-SALINERO, Jesus M, SUZUKI, Ken, BARTON, Paul J. R
Published in Circulation (New York, N.Y.) (21.06.2011)
Published in Circulation (New York, N.Y.) (21.06.2011)
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Journal Article
Expression of Extracellular Matrix Genes During Myocardial Recovery From Heart Failure After Left Ventricular Assist Device Support
Felkin, Leanne E., PhD, Lara-Pezzi, Enrique, PhD, George, Robert, MRCS, Yacoub, Magdi H., FRS, Birks, Emma J., MRCP, PhD, Barton, Paul J.R., PhD
Published in The Journal of heart and lung transplantation (01.02.2009)
Published in The Journal of heart and lung transplantation (01.02.2009)
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Journal Article
Choice of cell-delivery route for skeletal myoblast transplantation for treating post-infarction chronic heart failure in rat
Fukushima, Satsuki, Coppen, Steven R, Lee, Joon, Yamahara, Kenichi, Felkin, Leanne E, Terracciano, Cesare M N, Barton, Paul J R, Yacoub, Magdi H, Suzuki, Ken
Published in PloS one (27.08.2008)
Published in PloS one (27.08.2008)
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Journal Article
Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure
Lee, Rebecca, Xu, Bin, Rame, J. Eduardo, Felkin, Leanne E., Barton, Paul, Dries, Daniel L.
Published in Journal of the American Heart Association (01.12.2014)
Published in Journal of the American Heart Association (01.12.2014)
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Journal Article
Follistatin-Like 3 Mediates Paracrine Fibroblast Activation by Cardiomyocytes
Panse, Kalyani D., Felkin, Leanne E., López-Olañeta, Marina M., Gómez-Salinero, Jesús, Villalba, María, Muñoz, Lucía, Nakamura, Kazuto, Shimano, Masayuki, Walsh, Kenneth, Barton, Paul J. R., Rosenthal, Nadia, Lara-Pezzi, Enrique
Published in Journal of cardiovascular translational research (01.12.2012)
Published in Journal of cardiovascular translational research (01.12.2012)
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Journal Article
Heterogeneic nature of adult cardiac side population cells
Yamahara, Kenichi, Fukushima, Satsuki, Coppen, Steven R., Felkin, Leanne E., Varela-Carver, Anabel, Barton, Paul J.R., Yacoub, Magdi H., Suzuki, Ken
Published in Biochemical and biophysical research communications (11.07.2008)
Published in Biochemical and biophysical research communications (11.07.2008)
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Journal Article
Myocardial insulin-like growth factor-I gene expression during recovery from heart failure after combined left ventricular assist device and clenbuterol therapy
BARTON, Paul J. R, FELKIN, Leanne E, BIRKS, Emma J, CULLEN, Martin E, BANNER, Nicholas R, GRINDLE, Suzanne, HALL, Jennifer L, MILLER, Leslie W, YACOUB, Magdi H
Published in Circulation (New York, N.Y.) (30.08.2005)
Published in Circulation (New York, N.Y.) (30.08.2005)
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Journal Article
Overexpression of the transcription factor Hand1 causes predisposition towards arrhythmia in mice
Breckenridge, Ross A, Zuberi, Zia, Gomes, John, Orford, Robert, Dupays, Laurent, Felkin, Leanne E, Clark, James E, Magee, Anthony I, Ehler, Elisabeth, Birks, Emma J, Barton, Paul J.R, Tinker, Andrew, Mohun, Timothy J
Published in Journal of molecular and cellular cardiology (01.07.2009)
Published in Journal of molecular and cellular cardiology (01.07.2009)
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Journal Article
Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices
Birks, Emma J, Felkin, Leanne E, Banner, Nicholas R, Khaghani, Asghar, Barton, Paul J.R, Yacoub, Magdi H
Published in The Journal of heart and lung transplantation (01.02.2004)
Published in The Journal of heart and lung transplantation (01.02.2004)
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Journal Article
Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy
Heinig, Matthias, Adriaens, Michiel E, Schafer, Sebastian, van Deutekom, Hanneke W M, Lodder, Elisabeth M, Ware, James S, Schneider, Valentin, Felkin, Leanne E, Creemers, Esther E, Meder, Benjamin, Katus, Hugo A, Rühle, Frank, Stoll, Monika, Cambien, François, Villard, Eric, Charron, Philippe, Varro, Andras, Bishopric, Nanette H, George, Jr, Alfred L, Dos Remedios, Cristobal, Moreno-Moral, Aida, Pesce, Francesco, Bauerfeind, Anja, Rüschendorf, Franz, Rintisch, Carola, Petretto, Enrico, Barton, Paul J, Cook, Stuart A, Pinto, Yigal M, Bezzina, Connie R, Hubner, Norbert
Published in Genome Biology (14.09.2017)
Published in Genome Biology (14.09.2017)
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Journal Article
Increased expression of extracellular matrix regulators TIMP1 and MMP1 in deteriorating heart failure
Barton, Paul J.R, Birks, Emma J, Felkin, Leanne E, Cullen, Martin E, Koban, Maren U, Yacoub, Magdi H
Published in The Journal of heart and lung transplantation (01.07.2003)
Published in The Journal of heart and lung transplantation (01.07.2003)
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Journal Article
Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo
Clerk, Angela, Meijles, Daniel N, Hardyman, Michelle A, Fuller, Stephen J, Chothani, Sonia P, Cull, Joshua J, Cooper, Susanna T E, Alharbi, Hajed O, Vanezis, Konstantinos, Felkin, Leanne E, Markou, Thomais, Leonard, Samuel J, Shaw, Spencer W, Rackham, Owen J L, Cook, Stuart A, Glennon, Peter E, Sheppard, Mary N, Sembrat, John C, Rojas, Mauricio, McTiernan, Charles F, Barton, Paul J, Sugden, Peter H
Published in Biochemical journal (11.02.2022)
Published in Biochemical journal (11.02.2022)
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