Efficient production and enhanced tumor delivery of engineered extracellular vesicles
Watson, Dionysios C, Bayik, Defne, Srivatsan, Avinash, Bergamaschi, Cristina, Valentin, Antonio, Niu, Gang, Bear, Jenifer, Monninger, Mitchell, Sun, Mei, Morales-Kastresana, Aizea, Jones, Jennifer C, Felber, Barbara K, Chen, Xiaoyuan, Gursel, Ihsan, Pavlakis, George N
Published in Biomaterials (01.10.2016)
Published in Biomaterials (01.10.2016)
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Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
Bergamaschi, Cristina, Terpos, Evangelos, Rosati, Margherita, Angel, Matthew, Bear, Jenifer, Stellas, Dimitris, Karaliota, Sevasti, Apostolakou, Filia, Bagratuni, Tina, Patseas, Dimitris, Gumeni, Sentiljana, Trougakos, Ioannis P., Dimopoulos, Meletios A., Felber, Barbara K., Pavlakis, George N.
Published in Cell reports (Cambridge) (10.08.2021)
Published in Cell reports (Cambridge) (10.08.2021)
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Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes
Watson, Dionysios C, Moysi, Eirini, Valentin, Antonio, Bergamaschi, Cristina, Devasundaram, Santhi, Fortis, Sotirios P, Bear, Jenifer, Chertova, Elena, Bess, Jr, Julian, Sowder, Ray, Venzon, David J, Deleage, Claire, Estes, Jacob D, Lifson, Jeffrey D, Petrovas, Constantinos, Felber, Barbara K, Pavlakis, George N
Published in PLoS pathogens (01.02.2018)
Published in PLoS pathogens (01.02.2018)
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Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques
Rosati, Margherita, Agarwal, Mahesh, Hu, Xintao, Devasundaram, Santhi, Stellas, Dimitris, Chowdhury, Bhabadeb, Bear, Jenifer, Burns, Robert, Donohue, Duncan, Pessaint, Laurent, Andersen, Hanne, Lewis, Mark G, Terpos, Evangelos, Dimopoulos, Meletios Athanasios, Wlodawer, Alexander, Mullins, James I, Venzon, David J, Pavlakis, George N, Felber, Barbara K
Published in PLoS pathogens (22.09.2021)
Published in PLoS pathogens (22.09.2021)
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Oral Delivery of IL-27 Recombinant Bacteria Attenuates Immune Colitis in Mice
Hanson, Miranda L, Hixon, Julie A, Li, Wenqing, Felber, Barbara K, Anver, Miriam R, Stewart, C. Andrew, Janelsins, Brian M, Datta, Sandip K, Shen, Wei, McLean, Mairi H, Durum, Scott K
Published in Gastroenterology (New York, N.Y. 1943) (2014)
Published in Gastroenterology (New York, N.Y. 1943) (2014)
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Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10
Bergamaschi, Cristina, Pandit, Hrishikesh, Nagy, Bethany A, Stellas, Dimitris, Jensen, Shawn M, Bear, Jenifer, Cam, Maggie, Valentin, Antonio, Fox, Bernard A, Felber, Barbara K, Pavlakis, George N
Published in Journal for immunotherapy of cancer (01.05.2020)
Published in Journal for immunotherapy of cancer (01.05.2020)
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Heterodimeric IL-15 in Cancer Immunotherapy
Bergamaschi, Cristina, Stravokefalou, Vasiliki, Stellas, Dimitris, Karaliota, Sevasti, Felber, Barbara K, Pavlakis, George N
Published in Cancers (17.02.2021)
Published in Cancers (17.02.2021)
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CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control
Mothe, Beatriz, Llano, Anuska, Ibarrondo, Javier, Zamarreño, Jennifer, Schiaulini, Mattia, Miranda, Cristina, Ruiz-Riol, Marta, Berger, Christoph T, Herrero, M José, Palou, Eduard, Plana, Montse, Rolland, Morgane, Khatri, Ashok, Heckerman, David, Pereyra, Florencia, Walker, Bruce D, Weiner, David, Paredes, Roger, Clotet, Bonaventura, Felber, Barbara K, Pavlakis, George N, Mullins, James I, Brander, Christian
Published in PloS one (04.01.2012)
Published in PloS one (04.01.2012)
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A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques
Mothe, Beatriz, Hu, Xintao, Llano, Anuska, Rosati, Margherita, Olvera, Alex, Kulkarni, Viraj, Valentin, Antonio, Alicea, Candido, Pilkington, Guy R, Sardesai, Niranjan Y, Rocafort, Muntsa, Crespo, Manel, Carrillo, Jorge, Marco, Andrés, Mullins, James I, Dorrell, Lucy, Hanke, Tomáš, Clotet, Bonaventura, Pavlakis, George N, Felber, Barbara K, Brander, Christian
Published in Journal of translational medicine (15.02.2015)
Published in Journal of translational medicine (15.02.2015)
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Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques
Virnik, Konstantin, Rosati, Margherita, Medvedev, Alexei, Scanlan, Aaron, Walsh, Gabrielle, Dayton, Frances, Broderick, Kate E, Lewis, Mark, Bryson, Yvonne, Lifson, Jeffrey D, Ruprecht, Ruth M, Felber, Barbara K, Berkower, Ira
Published in PloS one (04.03.2020)
Published in PloS one (04.03.2020)
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Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum
Bergamaschi, Cristina, Bear, Jenifer, Rosati, Margherita, Beach, Rachel Kelly, Alicea, Candido, Sowder, Raymond, Chertova, Elena, Rosenberg, Steven A., Felber, Barbara K., Pavlakis, George N.
Published in Blood (05.07.2012)
Published in Blood (05.07.2012)
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Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection
Rosati, Margherita, Terpos, Evangelos, Ntanasis-Stathopoulos, Ioannis, Agarwal, Mahesh, Bear, Jenifer, Burns, Robert, Hu, Xintao, Korompoki, Eleni, Donohue, Duncan, Venzon, David J, Dimopoulos, Meletios-Athanasios, Pavlakis, George N, Felber, Barbara K
Published in Frontiers in immunology (26.11.2021)
Published in Frontiers in immunology (26.11.2021)
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SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors
Terpos, Evangelos, Stellas, Dimitris, Rosati, Margherita, Sergentanis, Theodoros N., Hu, Xintao, Politou, Marianna, Pappa, Vassiliki, Ntanasis-Stathopoulos, Ioannis, Karaliota, Sevasti, Bear, Jenifer, Donohue, Duncan, Pagoni, Maria, Grouzi, Elisavet, Korompoki, Eleni, Pavlakis, George N., Felber, Barbara K., Dimopoulos, Meletios A.
Published in European journal of internal medicine (01.07.2021)
Published in European journal of internal medicine (01.07.2021)
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HIV-1 conserved elements p24CE DNA vaccine induces humoral immune responses with broad epitope recognition in macaques
Kulkarni, Viraj, Valentin, Antonio, Rosati, Margherita, Rolland, Morgane, Mullins, James I, Pavlakis, George N, Felber, Barbara K
Published in PloS one (22.10.2014)
Published in PloS one (22.10.2014)
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Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes
Watson, Dionysios C., Yung, Bryant C., Bergamaschi, Cristina, Chowdhury, Bhabadeb, Bear, Jenifer, Stellas, Dimitris, Morales-Kastresana, Aizea, Jones, Jennifer C., Felber, Barbara K., Chen, Xiaoyuan, Pavlakis, George N.
Published in Journal of extracellular vesicles (01.12.2018)
Published in Journal of extracellular vesicles (01.12.2018)
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Live attenuated rubella vectors expressing Plasmodium falciparum circumsporozoite protein (Pf-CSP) provide a novel malaria vaccine platform in the rhesus macaque
Virnik, Konstantin, Zhou, Wenshuo, Medvedev, Alexei, Walsh, Gabrielle, Perry-Anderson, Jasper, Majam, Victoria, Felber, Barbara K., Kumar, Sanjai, Berkower, Ira
Published in Biochemical and biophysical research communications (05.11.2021)
Published in Biochemical and biophysical research communications (05.11.2021)
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Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population
Stellas, Dimitris, Karaliota, Sevasti, Stravokefalou, Vasiliki, Angel, Matthew, Nagy, Bethany A., Goldfarbmuren, Katherine C., Bergamaschi, Cristina, Felber, Barbara K., Pavlakis, George N.
Published in Cell reports (Cambridge) (30.05.2023)
Published in Cell reports (Cambridge) (30.05.2023)
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Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection
Fouts, Timothy R., Bagley, Kenneth, Prado, Ilia J., Bobb, Kathryn L., Schwartz, Jennifer A., Xu, Rong, Zagursky, Robert J., Egan, Michael A., Eldridge, John H., LaBranche, Celia C., Montefiori, David C., Le Buanec, Hélène, Zagury, Daniel, Pal, Ranajit, Pavlakis, George N., Felber, Barbara K., Franchini, Genoveffa, Gordon, Shari, Vaccari, Monica, Lewis, George K., DeVico, Anthony L., Gallo, Robert C.
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2015)
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