Towards a medically approved technology for alginate-based microcapsules allowing long-term immunoisolated transplantation
Zimmermann, H, Zimmermann, D, Reuss, R, Feilen, P J, Manz, B, Katsen, A, Weber, M, Ihmig, F R, Ehrhart, F, Gessner, P, Behringer, M, Steinbach, A, Wegner, L H, Sukhorukov, V L, Vásquez, J A, Schneider, S, Weber, M M, Volke, F, Wolf, R, Zimmermann, U
Published in Journal of materials science. Materials in medicine (01.06.2005)
Published in Journal of materials science. Materials in medicine (01.06.2005)
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Journal Article
Hepatocytes cultured in alginate microspheres: an optimized technique to study enzyme induction
Ringel, M., von Mach, M.A., Santos, R., Feilen, P.J., Brulport, M., Hermes, M., Bauer, A.W., Schormann, W., Tanner, B., Schön, M.R., Oesch, F., Hengstler, J.G.
Published in Toxicology (Amsterdam) (05.01.2005)
Published in Toxicology (Amsterdam) (05.01.2005)
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Journal Article
In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans
Schneider, S, Feilen, P J, Schreckenberger, M, Schwanstecher, M, Schwanstecher, C, Buchholz, H G, Thews, O, Oberholzer, K, Korobeynikov, A, Bauman, A, Comagic, S, Piel, M, Schirrmacher, E, Shiue, C Y, Alavi, A A, Bartenstein, P, Rösch, F, Weber, M M, Klein, H H, Schirrmacher, R
Published in Experimental and clinical endocrinology & diabetes (01.07.2005)
Published in Experimental and clinical endocrinology & diabetes (01.07.2005)
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Journal Article
Multilayer capsules: a promising microencapsulation system for transplantation of pancreatic islets
Schneider, Stephan, Feilen, Peter Johannes, Slotty, Viola, Kampfner, Daniel, Preuss, Simon, Berger, Svend, Beyer, Jürgen, Pommersheim, Rainer
Published in Biomaterials (01.07.2001)
Published in Biomaterials (01.07.2001)
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Journal Article
Size of pancreatic islets of Langerhans: a key parameter for viability after cryopreservation
VON MACH, M. A, SCHLOSSER, J, WEILAND, M, FEILEN, P. J, RINGEL, M, HENGSTLER, J. G, WEILEMANN, L. S, BEYER, J, KANN, P, SCHNEIDER, S
Published in Acta diabetologica (01.09.2003)
Published in Acta diabetologica (01.09.2003)
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Journal Article
Hydrogel-based encapsulation of biological, functional tissue : fundamentals, technologies and applications
ZIMMERMANN, H, EHRHART, F, WEBER, M. M, METZE, J, ZIMMERMANN, U, ZIMMERMANN, D, MÜLLER, K, KATSEN-GLOBA, A, BEHRINGER, M, FEILEN, P. J, GESSNER, P, ZIMMERMANN, G, SHIRLEY, S. G
Published in Applied physics. A, Materials science & processing (01.12.2007)
Published in Applied physics. A, Materials science & processing (01.12.2007)
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Journal Article
Long-Term Graft Function of Adult Rat and Human Islets Encapsulated in Novel Alginate-Based Microcapsules After Transplantation in Immunocompetent Diabetic Mice
SCHNEIDER, Stephan, FEILEN, Peter J, BRUNNENMEIER, Frank, MINNEMANN, Timo, ZIMMERMANN, Heiko, ZIMMERMANN, Ulrich, WEBER, Matthias M
Published in Diabetes (New York, N.Y.) (01.03.2005)
Published in Diabetes (New York, N.Y.) (01.03.2005)
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Journal Article
106. Intracellular inositol delivered through swelling-activated channels offers cryoprotection to Langerhans islets
Reuss, Randolph, Zimmermann, Heiko, Ehrhartb, Friedricke, Feilen, Peter J., Weber, Matthias M., Shirakashi, Ryo, Zimmermann, Ulrich, Sukhorukov, Vladimir L.
Published in Cryobiology (01.12.2006)
Published in Cryobiology (01.12.2006)
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Journal Article
102. Improved cryopreservation of pancreatic islets and multicellular spheroids in IBMT-miniaturized cryosubstrates
Zimmermann, Heiko, Katsen-Globa, Alisa, Ehrhart, Friederike, Reuss, Randolph, Feilen, Peter J., Sukhorukov, Vladimir L., Schneider, Stephan, Weber, Matthias M., Zimmermann, Ulrich
Published in Cryobiology (01.12.2006)
Published in Cryobiology (01.12.2006)
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Journal Article
Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential β-cell imaging agent
Wängler, Björn, Beck, Carmen, Shiue, Chyng Yann, Schneider, Stephan, Schwanstecher, Christina, Schwanstecher, Mathias, Feilen, Peter Johannes, Alavi, Abass, Rösch, Frank, Schirrmacher, Ralf
Published in Bioorganic & medicinal chemistry letters (18.10.2004)
Published in Bioorganic & medicinal chemistry letters (18.10.2004)
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Journal Article
Synthesis and first evaluation of new 18F-labelled sulfonylureas for the determination of the beta-cell status in vivo
Schirrmacher, R., Shiue, G., Shiue, S. J., Alavi, A., Feilen, P. J., Schneider, S., Beyer, J., Rösch, F.
Published in Journal of labelled compounds & radiopharmaceuticals (01.05.2001)
Published in Journal of labelled compounds & radiopharmaceuticals (01.05.2001)
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Journal Article
Synthesis and first evaluation of new 18 F‐labelled sulfonylureas for the determination of the beta‐cell status in vivo
Schirrmacher, R., Shiue, G., Shiue, S. J., Alavi, A., Feilen, P. J., Schneider, S., Beyer, J., Rösch, F.
Published in Journal of labelled compounds & radiopharmaceuticals (01.05.2001)
Published in Journal of labelled compounds & radiopharmaceuticals (01.05.2001)
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Journal Article
Improved cross linking of the Ba-alginate beads by the “Crystal Gun Method“ results in prolonged in vivo graft-function of microencapsulated islets of Langerhans
Feilen, PJ, Minnemann, T, Horn, L, Wiegand, F, Zimmermann, U, Weber, MM
Published in Experimental and Clinical Endocrinology & Diabetes (28.02.2006)
Published in Experimental and Clinical Endocrinology & Diabetes (28.02.2006)
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Conference Proceeding
A new, automated and miniaturized cryo-technique for the cryopreservation of rodent islet cells leads to markedly improved in vitro and in vivo graft function
Minnemann, T, Feilen, PJ, Katsen, A, Horn, L, Wiegand, F, Zimmermann, U, Zimmermann, H, Weber, MM
Published in Experimental and Clinical Endocrinology & Diabetes (28.02.2006)
Published in Experimental and Clinical Endocrinology & Diabetes (28.02.2006)
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Conference Proceeding
Humorale Faktoren aus MSC schützen kokultivierte β-Zellen vor Schädigung durch Alloxan und induzieren Proliferation
Lang, L, Liu, C, Feilen, PJ, Jäger, C, Alt, M, Päth, G, Seufert, J
Published in Diabetologie und Stoffwechsel (08.05.2012)
Published in Diabetologie und Stoffwechsel (08.05.2012)
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Conference Proceeding
Verbesserte Insulinfunktion unter Hochfettdiät-induzierter Lipotoxizität in transgenen Mäusen mit ektoper ß-Zell-spezifischer p8-Überexpression
Pilz, I, Päth, G, Feilen, PJ, Dufner, B, Rimmer, N, Alt, M, Seufert, J
Published in Diabetologie und Stoffwechsel (09.05.2011)
Published in Diabetologie und Stoffwechsel (09.05.2011)
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Conference Proceeding
Mesenchymale Stromazellen aus dem Knochenmark (MSC) reduzieren Streptozotozin (STZ)-induzierte Schädigung von Insulin produzierenden ß-Zellen durch humorale Faktoren in vitro
Feilen, PJ, Päth, G, Pilz, I, Jacob, M, Jäger, C, Alt, M, Seufert, J
Published in Diabetologie und Stoffwechsel (09.05.2011)
Published in Diabetologie und Stoffwechsel (09.05.2011)
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Conference Proceeding
[18F]Repaglinide: A Novel Radioligand for estimation of pancreatic islet-cell mass in vivo with Positron Emission Tomography (PET)
Schneider, S, Wängler, B, Thews, O, Schirrmacher, E, Comagic, S, Feilen, PJ, Schwanstecher, C, Schwanstecher, M, Piel, M, Rösch, F, Schirrmacher, R, Weber, MM
Published in Experimental and Clinical Endocrinology & Diabetes (02.03.2004)
Published in Experimental and Clinical Endocrinology & Diabetes (02.03.2004)
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Conference Proceeding