Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors
Sung, Pamela J., Tsai, Frederick D., Vais, Horia, Court, Helen, Yang, Jun, Fehrenbacher, Nicole, Foskett, J. Kevin, Philips, Mark R.
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2
Fehrenbacher, Nicole, Bastholm, Lone, Kirkegaard-Sørensen, Thomas, Rafn, Bo, Bøttzauw, Trine, Nielsen, Christina, Weber, Ekkehard, Shirasawa, Senji, Kallunki, Tuula, Jäättelä, Marja
Published in Cancer research (Chicago, Ill.) (15.08.2008)
Published in Cancer research (Chicago, Ill.) (15.08.2008)
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FKBP12 Binds to Acylated H-Ras and Promotes Depalmitoylation
Ahearn, Ian M., Tsai, Frederick D., Court, Helen, Zhou, Mo, Jennings, Benjamin C., Ahmed, Mahiuddin, Fehrenbacher, Nicole, Linder, Maurine E., Philips, Mark R.
Published in Molecular cell (21.01.2011)
Published in Molecular cell (21.01.2011)
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ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signaling Network Activating Myeloid Zinc Finger-1-Dependent Cathepsin B Expression
Rafn, Bo, Nielsen, Christian Friberg, Andersen, Sofie Hagel, Szyniarowski, Piotr, Corcelle-Termeau, Elisabeth, Valo, Erkka, Fehrenbacher, Nicole, Olsen, Charlotta Johanne, Daugaard, Mads, Egebjerg, Christina, Bøttzauw, Trine, Kohonen, Pekka, Nylandsted, Jesper, Hautaniemi, Sampsa, Moreira, José, Jäättelä, Marja, Kallunki, Tuula
Published in Molecular cell (30.03.2012)
Published in Molecular cell (30.03.2012)
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Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
Nylandsted, Jesper, Gyrd-Hansen, Mads, Danielewicz, Agnieszka, Fehrenbacher, Nicole, Lademann, Ulrik, Høyer-Hansen, Maria, Weber, Ekkehard, Multhoff, Gabriele, Rohde, Mikkel, Jäättelä, Marja
Published in The Journal of experimental medicine (16.08.2004)
Published in The Journal of experimental medicine (16.08.2004)
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Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation
Ostenfeld, Marie Stampe, Høyer-Hansen, Maria, Bastholm, Lone, Fehrenbacher, Nicole, Olsen, Ole Dines, Groth-Pedersen, Line, Puustinen, Pietri, Kirkegaard-Sørensen, Thomas, Nylandsted, Jesper, Farkas, Thomas, Jäättelä, Marja
Published in Autophagy (16.05.2008)
Published in Autophagy (16.05.2008)
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Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9
Gyrd-Hansen, Mads, Farkas, Thomas, Fehrenbacher, Nicole, Bastholm, Lone, Høyer-Hansen, Maria, Elling, Folmer, Wallach, David, Flavell, Richard, Kroemer, Guido, Nylandsted, Jesper, Jäättelä, Marja
Published in Molecular and Cellular Biology (01.11.2006)
Published in Molecular and Cellular Biology (01.11.2006)
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GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase
Kuchay, Shafi, Wang, Hui, Marzio, Antonio, Jain, Kunj, Homer, Harrison, Fehrenbacher, Nicole, Philips, Mark R., Zheng, Ning, Pagano, Michele
Published in Nature structural & molecular biology (01.07.2019)
Published in Nature structural & molecular biology (01.07.2019)
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Control of Macroautophagy by Calcium, Calmodulin-Dependent Kinase Kinase-β, and Bcl-2
Høyer-Hansen, Maria, Bastholm, Lone, Szyniarowski, Piotr, Campanella, Michelangelo, Szabadkai, György, Farkas, Thomas, Bianchi, Katiuscia, Fehrenbacher, Nicole, Elling, Folmer, Rizzuto, Rosario, Mathiasen, Ida Stenfeldt, Jäättelä, Marja
Published in Molecular cell (26.01.2007)
Published in Molecular cell (26.01.2007)
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Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens
Villa, Carlos H, Dao, Tao, Ahearn, Ian, Fehrenbacher, Nicole, Casey, Emily, Rey, Diego A, Korontsvit, Tatyana, Zakhaleva, Victoriya, Batt, Carl A, Philips, Mark R, Scheinberg, David A
Published in ACS nano (26.07.2011)
Published in ACS nano (26.07.2011)
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Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association
Zhou, Mo, Kuruvilla, Leena, Shi, Xiarong, Viviano, Stephen, Ahearn, Ian M., Amendola, Caroline R., Su, Wenjuan, Badri, Sana, Mahaffey, James, Fehrenbacher, Nicole, Skok, Jane, Schlessinger, Joseph, Turk, Benjamin E., Calderwood, David A., Philips, Mark R.
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2020)
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The G protein-coupled receptor GPR31 promotes membrane association of KRAS
Fehrenbacher, Nicole, Tojal da Silva, Israel, Ramirez, Craig, Zhou, Yong, Cho, Kwang-Jin, Kuchay, Shafi, Shi, Jie, Thomas, Susan, Pagano, Michele, Hancock, John F, Bar-Sagi, Dafna, Philips, Mark R
Published in The Journal of cell biology (07.08.2017)
Published in The Journal of cell biology (07.08.2017)
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Effective tumor cell death by σ-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress
OSTENFELD, Marie Stampe, FEHRENBACHER, Nicole, HØYER-HANSEN, Maria, THOMSEN, Christian, FARKAS, Thomas, JÄÄTTELÄ, Marja
Published in Cancer research (Chicago, Ill.) (01.10.2005)
Published in Cancer research (Chicago, Ill.) (01.10.2005)
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Journal Article
Correction for Gyrd-Hansen et al., "Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9"
Gyrd-Hansen, Mads, Farkas, Thomas, Fehrenbacher, Nicole, Bastholm, Lone, Høyer-Hansen, Maria, Elling, Folmer, Wallach, David, Flavell, Richard, Kroemer, Guido, Nylandsted, Jesper, Jäättelä, Marja
Published in Molecular and cellular biology (01.01.2018)
Published in Molecular and cellular biology (01.01.2018)
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Journal Article
Sensitization to the lysosomal cell death pathway upon immortalization and transformation
FEHRENBACHER, Nicole, GYRD-HANSEN, Mads, POULSEN, Birgit, FELBOR, Ute, KALLUNKI, Tuula, BOES, Marianne, WEBER, Ekkehard, LEIST, Marcel, JÄÄTTELÄ, Marja
Published in Cancer research (Chicago, Ill.) (01.08.2004)
Published in Cancer research (Chicago, Ill.) (01.08.2004)
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ErbB2 signaling pathways in the regulation of cathepsin activity
Kallunki, Tuula, Rafn, Bo, Szyniatowski, Piotr, Fehrenbacher, Nicole, Boettzauw, Trine, Nielsen, Christina, Nylandsted, Jesper, Jaeaettelae, Marja
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.05.2008)
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.05.2008)
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