Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts
Hansen, Brian J, Zhao, Jichao, Csepe, Thomas A, Moore, Brandon T, Li, Ning, Jayne, Laura A, Kalyanasundaram, Anuradha, Lim, Praise, Bratasz, Anna, Powell, Kimerly A, Simonetti, Orlando P, Higgins, Robert S D, Kilic, Ahmet, Mohler, Peter J, Janssen, Paul M L, Weiss, Raul, Hummel, John D, Fedorov, Vadim V
Published in European heart journal (14.09.2015)
Published in European heart journal (14.09.2015)
Get full text
Journal Article
Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacemaker compartments heterogeneity: A computer model analysis
Zhao, Jichao, Sharma, Roshan, Kalyanasundaram, Anuradha, Kennelly, James, Bai, Jieyun, Li, Ning, Panfilov, Alexander, Fedorov, Vadim V
Published in PLoS computational biology (18.12.2023)
Published in PLoS computational biology (18.12.2023)
Get full text
Journal Article
Fibrosis: a structural modulator of sinoatrial node physiology and dysfunction
Csepe, Thomas A, Kalyanasundaram, Anuradha, Hansen, Brian J, Zhao, Jichao, Fedorov, Vadim V
Published in Frontiers in physiology (12.02.2015)
Published in Frontiers in physiology (12.02.2015)
Get full text
Journal Article
Conduction Remodeling in Human End-Stage Nonischemic Left Ventricular Cardiomyopathy
GLUKHOV, Alexey V, FEDOROV, Vadim V, KALISH, Paul W, RAVIKUMAR, Vinod K, QING LOU, JANKS, Deborah, SCHUESSLER, Richard B, MOAZAMI, Nader, EFIMOV, Igor R
Published in Circulation (New York, N.Y.) (17.04.2012)
Published in Circulation (New York, N.Y.) (17.04.2012)
Get full text
Journal Article
Three‐dimensional Integrated Functional, Structural, and Computational Mapping to Define the Structural “Fingerprints” of Heart‐Specific Atrial Fibrillation Drivers in Human Heart Ex Vivo
Zhao, Jichao, Hansen, Brian J., Wang, Yufeng, Csepe, Thomas A., Sul, Lidiya V., Tang, Alan, Yuan, Yiming, Li, Ning, Bratasz, Anna, Powell, Kimerly A., Kilic, Ahmet, Mohler, Peter J., Janssen, Paul M. L., Weiss, Raul, Simonetti, Orlando P., Hummel, John D., Fedorov, Vadim V.
Published in Journal of the American Heart Association (01.08.2017)
Published in Journal of the American Heart Association (01.08.2017)
Get full text
Journal Article
In silico investigation of the mechanisms underlying atrial fibrillation due to impaired Pitx2
Bai, Jieyun, Lo, Andy, Gladding, Patrick A, Stiles, Martin K, Fedorov, Vadim V, Zhao, Jichao
Published in PLoS computational biology (25.02.2020)
Published in PLoS computational biology (25.02.2020)
Get full text
Journal Article
Redundant and diverse intranodal pacemakers and conduction pathways protect the human sinoatrial node from failure
Li, Ning, Hansen, Brian J, Csepe, Thomas A, Zhao, Jichao, Ignozzi, Anthony J, Sul, Lidiya V, Zakharkin, Stanislav O, Kalyanasundaram, Anuradha, Davis, Jonathan P, Biesiadecki, Brandon J, Kilic, Ahmet, Janssen, Paul M L, Mohler, Peter J, Weiss, Raul, Hummel, John D, Fedorov, Vadim V
Published in Science translational medicine (26.07.2017)
Published in Science translational medicine (26.07.2017)
Get more information
Journal Article
Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node
Li, Ning, Kalyanasundaram, Anuradha, Hansen, Brian J, Artiga, Esthela J, Sharma, Roshan, Abudulwahed, Suhaib H, Helfrich, Katelynn M, Rozenberg, Galina, Wu, Pei-Jung, Zakharkin, Stanislav, Gyorke, Sandor, Janssen, Paul Ml, Whitson, Bryan A, Mokadam, Nahush A, Biesiadecki, Brandon J, Accornero, Federica, Hummel, John D, Mohler, Peter J, Dobrzynski, Halina, Zhao, Jichao, Fedorov, Vadim V
Published in Nature communications (24.01.2020)
Published in Nature communications (24.01.2020)
Get full text
Journal Article
Exercise training-induced bradycardia: evidence for enhanced parasympathetic regulation without changes in intrinsic sinoatrial node function
Billman, George E, Cagnoli, Kristen L, Csepe, Thomas, Li, Ning, Wright, Patrick, Mohler, Peter J, Fedorov, Vadim V
Published in Journal of applied physiology (1985) (01.06.2015)
Published in Journal of applied physiology (1985) (01.06.2015)
Get full text
Journal Article
Application of blebbistatin as an excitation-contraction uncoupler for electrophysiologic study of rat and rabbit hearts
Fedorov, Vadim V, Lozinsky, Ilya T, Sosunov, Eugene A, Anyukhovsky, Evgeniy P, Rosen, Michael R, Balke, C William, Efimov, Igor R
Published in Heart rhythm (01.05.2007)
Published in Heart rhythm (01.05.2007)
Get more information
Journal Article
Altered microRNA and mRNA profiles during heart failure in the human sinoatrial node
Li, Ning, Artiga, Esthela, Kalyanasundaram, Anuradha, Hansen, Brian J, Webb, Amy, Pietrzak, Maciej, Biesiadecki, Brandon, Whitson, Bryan, Mokadam, Nahush A, Janssen, Paul M L, Hummel, John D, Mohler, Peter J, Dobrzynski, Halina, Fedorov, Vadim V
Published in Scientific reports (29.09.2021)
Published in Scientific reports (29.09.2021)
Get full text
Journal Article
Calcium-activated potassium current modulates ventricular repolarization in chronic heart failure
Bonilla, Ingrid M, Long, 3rd, Victor P, Vargas-Pinto, Pedro, Wright, Patrick, Belevych, Andriy, Lou, Qing, Mowrey, Kent, Yoo, Jae, Binkley, Philip F, Fedorov, Vadim V, Györke, Sandor, Janssen, Paulus M L, Kilic, Ahmet, Mohler, Peter J, Carnes, Cynthia A
Published in PloS one (01.10.2014)
Published in PloS one (01.10.2014)
Get full text
Journal Article
Atrial fibrillation driver mechanisms: Insight from the isolated human heart
Csepe, Thomas A., BSc, Hansen, Brian J., BSc, Fedorov, Vadim V., PhD
Published in Trends in cardiovascular medicine (01.01.2017)
Published in Trends in cardiovascular medicine (01.01.2017)
Get full text
Journal Article
Silencing miR-370-3p rescues funny current and sinus node function in heart failure
Yanni, Joseph, D'Souza, Alicia, Wang, Yanwen, Li, Ning, Hansen, Brian J, Zakharkin, Stanislav O, Smith, Matthew, Hayward, Christina, Whitson, Bryan A, Mohler, Peter J, Janssen, Paul M L, Zeef, Leo, Choudhury, Moinuddin, Zi, Min, Cai, Xue, Logantha, Sunil Jit R J, Nakao, Shu, Atkinson, Andrew, Petkova, Maria, Doris, Ursula, Ariyaratnam, Jonathan, Cartwright, Elizabeth J, Griffiths-Jones, Sam, Hart, George, Fedorov, Vadim V, Oceandy, Delvac, Dobrzynski, Halina, Boyett, Mark R
Published in Scientific reports (09.07.2020)
Published in Scientific reports (09.07.2020)
Get full text
Journal Article
Optical Mapping of the Isolated Coronary-Perfused Human Sinus Node
Fedorov, Vadim V., PhD, Glukhov, Alexey V., PhD, Chang, Roger, BSc, Kostecki, Geran, BSc, Aferol, Hyuliya, BSc, Hucker, William J., MD, PhD, Wuskell, Joseph P., PhD, Loew, Leslie M., PhD, Schuessler, Richard B., PhD, Moazami, Nader, MD, Efimov, Igor R., PhD
Published in Journal of the American College of Cardiology (19.10.2010)
Published in Journal of the American College of Cardiology (19.10.2010)
Get full text
Journal Article
Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart
Li, Ning, Csepe, Thomas A, Hansen, Brian J, Dobrzynski, Halina, Higgins, Robert S D, Kilic, Ahmet, Mohler, Peter J, Janssen, Paul M L, Rosen, Michael R, Biesiadecki, Brandon J, Fedorov, Vadim V
Published in Circulation. Arrhythmia and electrophysiology (01.10.2015)
Published in Circulation. Arrhythmia and electrophysiology (01.10.2015)
Get full text
Journal Article