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Peptidomimetic Inhibitors of the Human Cytomegalovirus Protease
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Published in Journal of medicinal chemistry (13.09.2012)
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Multi-parameter optimization of aza-follow-ups to BI 207524, a thumb pocket 1 HCV NS5B polymerase inhibitor. Part 2: Impact of lipophilicity on promiscuity and in vivo toxicity
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Published in Bioorganic & medicinal chemistry letters (01.03.2015)
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Discovery of BI 207524, an Indole Diamide NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection
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Published in Journal of medicinal chemistry (11.12.2014)
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Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay
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Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype
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Published in Bioorganic & medicinal chemistry letters (15.07.2013)
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
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Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.05.2013)
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Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus
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Published in Bioorganic & medicinal chemistry letters (01.07.2013)
Published in Bioorganic & medicinal chemistry letters (01.07.2013)
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Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV)
Beaulieu, Pierre L, Bös, Michael, Cordingley, Michael G, Chabot, Catherine, Fazal, Gulrez, Garneau, Michel, Gillard, James R, Jolicoeur, Eric, LaPlante, Steven, McKercher, Ginette, Poirier, Martin, Poupart, Marc-André, Tsantrizos, Youla S, Duan, Jianmin, Kukolj, George
Published in Journal of medicinal chemistry (28.08.2014)
Published in Journal of medicinal chemistry (28.08.2014)
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Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives
Beaulieu, Pierre L, Bös, Michael, Bousquet, Yves, Fazal, Gulrez, Gauthier, Jean, Gillard, James, Goulet, Sylvie, LaPlante, Steven, Poupart, Marc-André, Lefebvre, Sylvain, McKercher, Ginette, Pellerin, Charles, Austel, Volkhard, Kukolj, George
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency
BEAULIEU, Pierre L, BÖS, Michael, VALOIS, Serge, KUKOLJ, George, BOUSQUET, Yves, DEROY, Patrick, FAZAL, Gulrez, GAUTHIER, Jean, GILLARD, James, GOULET, Sylvie, MCKERCHER, Ginette, POUPART, Marc-André
Published in Bioorganic & medicinal chemistry letters (23.02.2004)
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Peptide-based inhibitors of the hepatitis C virus serine protease
Llinàs-Brunet, Montse, Bailey, Murray, Fazal, Gulrez, Goulet, Sylvie, Halmos, Ted, Laplante, Steven, Maurice, Roger, Poirier, Martin, Poupart, Marc-André, Thibeault, Diane, Wernic, Dominik, Lamarre, Daniel
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
Published in Bioorganic & medicinal chemistry letters (07.07.1998)
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Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors
Llinàs-Brunet, Montse, Bailey, Murray, Fazal, Gulrez, Ghiro, Elise, Gorys, Vida, Goulet, Sylvie, Halmos, Ted, Maurice, Roger, Poirier, Martin, Poupart, Marc-André, Rancourt, Jean, Thibeault, Diane, Wernic, Dominik, Lamarre, Daniel
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
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Solid-Phase Synthesis of Peptidyl Trifluoromethyl Ketones
Poupart, Marc-André, Fazal, Gulrez, Goulet, Sylvie, Mar, Ly Thy
Published in Journal of organic chemistry (19.02.1999)
Published in Journal of organic chemistry (19.02.1999)
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Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease
Llinàs-Brunet, Montse, Bailey, Murray, Déziel, Robert, Fazal, Gulrez, Gorys, Vida, Goulet, Sylvie, Halmos, Ted, Maurice, Roger, Poirier, Martin, Poupart, Marc-André, Rancourt, Jean, Thibeault, Diane, Wernic, Dominik, Lamarre, Daniel
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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Discovery of non-peptidic P2-P3 butanediamide renin inhibitors with high oral efficacy
Simoneau, B, Lavallée, P, Anderson, P C, Bailey, M, Bantle, G, Berthiaume, S, Chabot, C, Fazal, G, Halmos, T, Ogilvie, W W, Poupart, M A, Thavonekham, B, Xin, Z, Thibeault, D, Bolger, G, Panzenbeck, M, Winquist, R, Jung, G L
Published in Bioorganic & medicinal chemistry (01.03.1999)
Published in Bioorganic & medicinal chemistry (01.03.1999)
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Discovery of non-peptidic P 2 –P 3 butanediamide renin inhibitors with high oral efficacy
Simoneau, Bruno, Lavallée, Pierre, Anderson, Paul C., Bailey, Murray, Bantle, Gary, Berthiaume, Sylvie, Chabot, Catherine, Fazal, Gulrez, Halmos, Ted, Ogilvie, William W., Poupart, Marc-André, Thavonekham, Bounkham, Xin, Zhili, Thibeault, Diane, Bolger, Gordon, Panzenbeck, Maret, Winquist, Raymond, Jung, Grace L.
Published in Bioorganic & medicinal chemistry (01.03.1999)
Published in Bioorganic & medicinal chemistry (01.03.1999)
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VIRAL POLYMERASE INHIBITORS
COULOMBE, RENE, FAZAL, GULREZ, STAMMERS, TIMOTHY, RANCOURT, JEAN, THAVONEKHAM, BOUNKHAM
Year of Publication 22.02.2012
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Year of Publication 22.02.2012
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