Modulators of the human CCR5 receptor. Part 3: SAR of substituted 1-[3-(4-methanesulfonylphenyl)-3-phenylpropyl]-piperidinyl phenylacetamides
Cumming, John G., Brown, Simon J., Cooper, Anne E., Faull, Alan W., Flynn, Anthony P., Grime, Ken, Oldfield, John, Shaw, John S., Shepherd, Emma, Tucker, Howard, Whittaker, David
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
Published in Bioorganic & medicinal chemistry letters (01.07.2006)
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Balancing hERG affinity and absorption in the discovery of AZD5672, an orally active CCR5 antagonist for the treatment of rheumatoid arthritis
Cumming, John G., Tucker, Howard, Oldfield, John, Fielding, Colin, Highton, Adrian, Faull, Alan, Wild, Martin, Brown, Dearg, Wells, Stuart, Shaw, John
Published in Bioorganic & medicinal chemistry letters (15.02.2012)
Published in Bioorganic & medicinal chemistry letters (15.02.2012)
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Dual-Acting Thromboxane Receptor Antagonist/Synthase Inhibitors: Synthesis and Biological Properties of [2-Substituted-4-(3-pyridyl)-1,3-dioxan-5-yl]alkenoic Acids
Faull, Alan W, Brewster, Andrew G, Brown, George R, Smithers, Michael J, Jackson, Ruth
Published in Journal of medicinal chemistry (01.02.1995)
Published in Journal of medicinal chemistry (01.02.1995)
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The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity
Cumming, John G., Bower, Justin F., Waterson, David, Faull, Alan, Poyser, Philip J., Turner, Paul, McDermott, Benjamin, Campbell, Andrew D., Hudson, Julian, James, Michael, Winter, Jon, Wood, Christine
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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Journal Article
PYRIDINE DERIVATIVES
BROWN, GEORGE ROBERT, BREWSTER, ANDREW GEORGE, JESSUP, REGINALD, SMITHERS, MRCHAEL JAMES, FAULL, ALAN WELLINGTON
Year of Publication 17.08.1998
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Year of Publication 17.08.1998
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