Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus
Xu, Jiayi, Lin, Songnian, Myers, Robert W., Addona, George, Berger, Joel P., Campbell, Brian, Chen, Hsuan-shen, Chen, Zhesheng, Eiermann, George J., Elowe, Nadine H., Farrer, Brian T., Feng, Wen, Fu, Qinghong, Kats-Kagan, Roman, Kavana, Michael, Malkani, Sunita, McMasters, Daniel R., Mitra, Kaushik, Pachanski, Michele J., Tong, Xinchun, Trujillo, Maria E., Xu, Libo, Zhang, Bei, Zhang, Fengqi, Zhang, Rui, Parmee, Emma R.
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
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Journal Article
Inhaled “Muco‐Trapping” Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections
McSweeney, Morgan D., Alnajjar, Sarhad, Schaefer, Alison M., Richardson, Zach, Wolf, Whitney, Stewart, Ian, Sriboonyapirat, Pun, McCallen, Justin, Farmer, Ellen, Nzati, Bernadette, Lord, Sam, Farrer, Brian, Moench, Thomas R., Kumar, Priya A., Arora, Harendra, Pickles, Raymond J., Hickey, Anthony J., Ackermann, Mark, Lai, Samuel K.
Published in Advanced science (01.03.2024)
Published in Advanced science (01.03.2024)
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Journal Article
Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus
Xu, Jiayi, Lin, Songnian, Myers, Robert W., Trujillo, Maria E., Pachanski, Michele J., Malkani, Sunita, Chen, Hsuan-shen, Chen, Zhesheng, Campbell, Brian, Eiermann, George J., Elowe, Nadine, Farrer, Brian T., Feng, Wen, Fu, Qinghong, Kats-Kagan, Roman, Kavana, Michael, McMasters, Daniel R., Mitra, Kaushik, Tong, Xinchun, Xu, Libo, Zhang, Fengqi, Zhang, Rui, Addona, George H., Berger, Joel P., Zhang, Bei, Parmee, Emma R.
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
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Journal Article
Engineering a “muco‐trapping” ACE2‐immunoglobulin hybrid with picomolar affinity as an inhaled, pan‐variant immunotherapy for COVID‐19
Tiruthani, Karthik, Cruz‐Teran, Carlos, Chan, Jasper F. W., Ma, Alice, McSweeney, Morgan, Wolf, Whitney, Yuan, Shoufeng, Poon, Vincent K. M., Chan, Chris C. S., Botta, Lakshmi, Farrer, Brian, Stewart, Ian, Schaefer, Alison, Edelstein, Jasmine, Kumar, Priya, Arora, Harendra, Hutchins, Jeff T., Hickey, Anthony J., Yuen, Kwok‐Yung, Lai, Samuel K.
Published in Bioengineering & translational medicine (01.07.2024)
Published in Bioengineering & translational medicine (01.07.2024)
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Journal Article
Comparison of the Binding of Cadmium(II), Mercury(II), and Arsenic(III) to the de Novo Designed Peptides TRI L12C and TRI L16C
Matzapetakis, Manolis, Farrer, Brian T, Weng, Tsu-Chien, Hemmingsen, Lars, Penner-Hahn, James E, Pecoraro, Vincent L
Published in Journal of the American Chemical Society (10.07.2002)
Published in Journal of the American Chemical Society (10.07.2002)
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Journal Article
Risk Assessment and Physicochemical Characterization of a Metastable Dihydrate API Phase for Intravenous Formulation Development
Mortko, Christopher J., Sheth, Agam R., Variankaval, Narayan, Li, Li, Farrer, Brian T.
Published in Journal of pharmaceutical sciences (01.12.2010)
Published in Journal of pharmaceutical sciences (01.12.2010)
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Journal Article
Quantitation of Crystalline Material within a Liquid Vehicle using 1H/19F CP/MAS NMR
Farrer, Brian T., Peresypkin, Andrey, Wenslow, Robert M.
Published in Journal of pharmaceutical sciences (01.02.2007)
Published in Journal of pharmaceutical sciences (01.02.2007)
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Journal Article
Arsenic(III)−Cysteine Interactions Stabilize Three-Helix Bundles in Aqueous Solution
Farrer, Brian T, McClure, Craig P, Penner-Hahn, James E, Pecoraro, Vincent L
Published in Inorganic chemistry (27.11.2000)
Published in Inorganic chemistry (27.11.2000)
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Journal Article
Multimodal imaging of drug and excipients in rat lungs following an inhaled administration of controlled-release drug laden PLGA microparticles
Robinson, Eve, Giffen, Paul, Hassall, Dave, Ball, Doug, Reid, Heather, Coe, Diane, Teague, Simon, Terry, Rebecca, Earl, Meredith, Marchand, Joseph, Farrer, Brian, Havelund, Rasmus, Gilmore, Ian S, Marshall, Peter S
Published in Analyst (London) (21.05.2021)
Published in Analyst (London) (21.05.2021)
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Journal Article
리바비린의 약학적 조성물
ROBERTS CHRISTOPHER D, SAVAGE JOHN ROBERT, SPRAGUE JACOB J, DELL'ORCO PHILIP CHARLES, WANG YONGCAI, FARRER BRIAN T, HONG ZHI
Year of Publication 11.07.2018
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Year of Publication 11.07.2018
Patent
Heavy-metal complexation by de novo peptide design
Farrer, Brian T, Pecoraro, Vincent L
Published in Current opinion in drug discovery & development (01.11.2002)
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Published in Current opinion in drug discovery & development (01.11.2002)
Journal Article
Probing metallopeptide folding mechanisms using de novo design peptides
Pecoraro, Vincent L., Farrer, Brian, Matzepetakis, Manolis, Ghosh, Debdip
Published in Journal of inorganic biochemistry (15.07.2003)
Published in Journal of inorganic biochemistry (15.07.2003)
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Journal Article
Dry Powder Treprostinil for the Treatment of Pulmonary Hypertension
Maynor, Benjamin, Roscigno, Robert Frank, Farrer, Brian T, Sprague, Jacob J
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
Patent