Combination Treatment of the Oral CHK1 Inhibitor, SRA737, and Low-Dose Gemcitabine Enhances the Effect of Programmed Death Ligand 1 Blockade by Modulating the Immune Microenvironment in SCLC
Sen, Triparna, Della Corte, Carminia M., Milutinovic, Snezana, Cardnell, Robert J., Diao, Lixia, Ramkumar, Kavya, Gay, Carl M., Stewart, C. Allison, Fan, Youhong, Shen, Li, Hansen, Ryan J., Strouse, Bryan, Hedrick, Michael P., Hassig, Christian A., Heymach, John V., Wang, Jing, Byers, Lauren A.
Published in Journal of thoracic oncology (01.12.2019)
Published in Journal of thoracic oncology (01.12.2019)
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Journal Article
Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers
Nilsson, Monique B, Sun, Huiying, Diao, Lixia, Tong, Pan, Liu, Diane, Li, Lerong, Fan, Youhong, Poteete, Alissa, Lim, Seung-Oe, Howells, Kathryn, Haddad, Vincent, Gomez, Daniel, Tran, Hai, Pena, Guillermo Armaiz, Sequist, Lecia V, Yang, James C, Wang, Jing, Kim, Edward S, Herbst, Roy, Lee, J Jack, Hong, Waun Ki, Wistuba, Ignacio, Hung, Mien-Chie, Sood, Anil K, Heymach, John V
Published in Science translational medicine (08.11.2017)
Published in Science translational medicine (08.11.2017)
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The extensin protein SAE1 plays a role in leaf senescence and is targeted by the ubiquitin ligase SlSINA4 in tomato
Lu, Han, Niu, Xiangli, Fan, Youhong, Yuan, Yulin, Huang, Li, Zhao, Bingyu, Liu, Yongsheng, Xiao, Fangming
Published in Journal of experimental botany (27.06.2023)
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Published in Journal of experimental botany (27.06.2023)
Journal Article
Abstract 1960: T790M-independent EGFR TKI resistance is associated with a broad multi-drug resistant phenotype but selective vulnerabilities to spindle assembly complex (SAC) and CDK inhibitors
Nilsson, Monique B., Robichaux, Jacqueline, Sun, Huiying, Tong, Pan, Diao, Lixia, Hofstad, Mia, Fan, YouHong, Wang, Jing, Heymach, John
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado
Galan-Cobo, Ana, Stellrecht, Christine M, Yilmaz, Emrullah, Yang, Chao, Qian, Yu, Qu, Xiao, Akhter, Ishita, Ayres, Mary L, Fan, Youhong, Tong, Pan, Diao, Lixia, Ding, Jie, Giri, Uma, Gudikote, Jayanthi, Nilsson, Monique, Wierda, William G, Wang, Jing, Skoulidis, Ferdinandos, Minna, John D, Gandhi, Varsha, Heymach, John V
Published in Molecular cancer research (01.02.2022)
Published in Molecular cancer research (01.02.2022)
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Journal Article
Abstract 3870: SLFN11 is a biomarker of sensitivity to PARP inhibition and chemotherapy in small cell lung cancer (SCLC)
Stewart, C. Allison, Tong, Pan, Cardnell, Robert, Sen, Triparna, Masrorpour, Fatemah Mina, Fan, Youhong, Wang, Jing, Byers, Lauren Averett
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer
Gomez, Daniel Richard, Byers, Lauren Averett, Nilsson, Monique, Diao, Lixia, Wang, Jing, Li, Lerong, Tong, Pan, Hofstad, Mia, Saigal, Babita, Wistuba, Ignacio, Kalhor, Neda, Swisher, Stephen, Fan, Youhong, Hong, Waun Ki, Suraokar, Milind, Behrens, Carmen, Moran, Cesar, Heymach, John Victor
Published in Oncotarget (06.03.2018)
Published in Oncotarget (06.03.2018)
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Journal Article
STING pathway expression identifies non-small cell lung cancers with an immune-responsive phenotype
Corte, Carminia M. Della, Sen, Triparna, Gay, Carl M., Ramkumar, Kavya, Diao, Lixia, Cardnell, Robert J., Rodriguez, B. Leticia, Stewart, C. Allison, Papadimitrakopoulou, Vassiliki A., Gibson, Laura, Fradette, Jared J., Wang, Qi, Fan, Youhong, Peng, David H., Negrao, Marcelo V., Witsuba, Ignacio I., Fujimoto, Junya, Soto, Luisa M. Solis, Behrens, Carmen, Skoulidis, Ferdinandos, Heymach, John V., Wang, Jing, Gibbons, Don L., Byers, Lauren A.
Published in Journal of thoracic oncology (15.02.2020)
Published in Journal of thoracic oncology (15.02.2020)
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Journal Article
Abstract A108: DNA damage repair targeting upregulates PD-L1 level and potentiates the effect of PD-L1 blockade in small cell lung cancer
Sen, Triparna, Chen, Limo, Rodriguez, B. Leticia, Gay, Carl M., Li, Lerong, Li, Yanli, Fan, Youhong, Glisson, Bonnie, Wang, Jing, Piwnica-Worms, Helen, Sage, Julien, Heymach, John V., Gibbons, Don L., Byers, Lauren A.
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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Journal Article
Biomarker-Integrated Neoadjuvant Dasatinib Trial in Resectable Malignant Pleural Mesothelioma
Tsao, Anne S., Lin, Heather, Carter, Brett W., Lee, J. Jack, Rice, David, Vaporcyan, Ara, Swisher, Steven, Mehran, Reza, Heymach, John, Nilsson, Monique, Fan, Youhong, Nunez, Maria, Diao, Lixia, Wang, Jing, Fujimoto, Junya, Wistuba, Ignacio I., Hong, Waun Ki
Published in Journal of thoracic oncology (01.02.2018)
Published in Journal of thoracic oncology (01.02.2018)
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Journal Article
Abstract 567: CD38 blockade overcomes the immune resistance to anti-PD-L1 therapy by boosting CD8 T cell response
Chen, Limo, Diao, Lixia, Yang, Yongbin, Yi, Xiaohui, Rodriguez, Jaime, Fan, Youhong, Rodriguez, Leticia, Fradette, Jared, Ungewiss, Christin, Roybal, Jonothan, Zhu, Jingfen, Wang, Jing, Byers, Lauren, Ullrich, Stephen, Wistuba, Ignacio, Heymach, John, Qin, Xiao-Feng, Gibbons, Don
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib
Nilsson, Monique B, Giri, Uma, Gudikote, Jayanthi, Tang, Ximing, Lu, Wei, Tran, Hai, Fan, Youhong, Koo, Andrew, Diao, Lixia, Tong, Pan, Wang, Jing, Herbst, Roy, Johnson, Bruce E, Ryan, Andy, Webster, Alan, Rowe, Philip, Wistuba, Ignacio I, Heymach, John V
Published in Clinical cancer research (15.04.2016)
Published in Clinical cancer research (15.04.2016)
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Journal Article
Combination treatment of the oral CHK1 inhibitor, SRA737 and low dose gemcitabine, enhances the effect of PD-L1 blockade by modulating the immune microenvironment in small cell lung cancer
Sen, Triparna, Della Corte, Carminia M., Milutinovic, Snezana, Cardnell, Robert J, Diao, Lixia, Ramkumar, Kavya, Gay, Carl M., Stewart, C Allison, Fan, Youhong, Shen, Li, Hansen, Ryan J., Strouse, Bryan, Hedrick, Michael P., Hassig, Christian A., Heymach, John V., Wang, Jing, Byers, Lauren A
Published in Journal of thoracic oncology (27.08.2019)
Published in Journal of thoracic oncology (27.08.2019)
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Journal Article
Abstract 2118: Nonsense-mediated decay regulates the expression of tumor suppressor transcripts and cancer pathways in non-small cell lung cancer cell lines
Gudikote, Jayanthi P., Zhao, Hao, Wang, Jing, Fan, Youhong, Diao, Lixia, Byers, Lauren A., Giri, Uma, Nilsson, Monique, Heymach, John V.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 4662: Beta blockers abrogate EGFR TKI resistance induced by adrenergic receptor-mediated upregulation of IL-6 and modulation of the LKB1/AMPK/mTOR axis
Nilsson, Monique B., Sun, Huiying, Diao, Lixia, Tong, Pan, Fan, Youhong, Tran, Hai, Liu, Diane, Armaiz Pena, Guillermo, Wang, Jing, Rowe, Phil, Webster, Alan, Lee, Jack, Gomez, Daniel, Hong, Waun Ki, Wistuba, Ignacio, Sood, Anil, Heymach, John
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Targeting DNA damage response promotes anti-tumor immunity through STING-mediated T-cell activation in small cell lung cancer
Sen, Triparna, Rodriguez, B. Leticia, Chen, Limo, Corte, Carminia Della, Morikawa, Naoto, Fujimoto, Junya, Cristea, Sandra, Nguyen, Thuyen, Diao, Lixia, Li, Lerong, Fan, Youhong, Yang, Yongbin, Wang, Jing, Glisson, Bonnie S., Wistuba, Ignacio I., Sage, Julien, Heymach, John V., Gibbons, Don L., Byers, Lauren A.
Published in Cancer discovery (18.02.2019)
Published in Cancer discovery (18.02.2019)
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Journal Article
Ubiquitin‐conjugated degradation of golden 2‐like transcription factor is mediated by CUL 4‐ DDB 1‐based E 3 ligase complex in tomato
Tang, Xiaofeng, Miao, Min, Niu, Xiangli, Zhang, Danfeng, Cao, Xulv, Jin, Xichen, Zhu, Yunye, Fan, Youhong, Wang, Hongtao, Liu, Ying, Sui, Yuan, Wang, Wenjie, Wang, Anquan, Xiao, Fangming, Giovannoni, Jim, Liu, Yongsheng
Published in The New phytologist (01.02.2016)
Published in The New phytologist (01.02.2016)
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Journal Article
Abstract 3623: Neoadjuvant chemotherapy is associated with increased expression of DNA repair proteins and epithelial to mesenchymal transition (EMT) in patients with non-small cell lung cancer (NSCLC)
Gomez, Daniel R., Diao, Lixia, Wang, Jing, Wistuba, Ignacio I., Moran, Cesar, Kalhor, Neda, Suraokar, Milind B., Swisher, Stephen G., Behrens, Carmen, Fan, Youhong, Heymach, John V., Byers, Lauren A.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 3364: Epithelial-mesenchymal transition is associated with a profound inflammatory tumor microenvironment in lung adenocarcinoma
Lou, Yanyan, Diao, Lixia, Roger, Parra Cuentas Edwin, Denning, Warren L., Chen, Limo, Fan, Youhong, Rodriguez, Jaime, Byers, Lauren, Wang, Jing, Papadimitrakopoulou, Vassiliki, Carmen, Behrens, Wistuba, Ignacio I., Hwu, Patrick, Heymach, John V., Gibbons, Don L.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Abstract 1589: LKB1 overexpression regulates DNA repair pathway and sensitivity to radiation in LKB1 mutant non-small cell lung cancer cell lines
Yang, Chao, Giri, Uma, Cortez, Maria Angelica, Gudikote, Jayanthi, Fan, YouHong, Diao, Lixia, Byers, Lauren A., Heymach, John V.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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