A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow
Wynn, Robert F., Hart, Claire A., Corradi-Perini, Carla, O'Neill, Liam, Evans, Caroline A., Wraith, J. Ed, Fairbairn, Leslie J., Bellantuono, Ilaria
Published in Blood (01.11.2004)
Published in Blood (01.11.2004)
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Journal Article
Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
Chinnasamy, Dhanalakshmi, Milsom, Michael D, Shaffer, James, Neuenfeldt, James, Shaaban, Aimen F, Margison, Geoffrey P, Fairbairn, Leslie J, Chinnasamy, Nachimuthu
Published in Virology journal (15.03.2006)
Published in Virology journal (15.03.2006)
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Journal Article
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-α on Fanconi anemia hematopoietic stem and progenitor cells
Milsom, Michael D., Schiedlmeier, Bernhard, Bailey, Jeff, Kim, Mi-Ok, Li, Dandan, Jansen, Michael, Ali, Abdullah Mahmood, Kirby, Michelle, Baum, Christopher, Fairbairn, Leslie J., Williams, David A.
Published in Blood (21.05.2009)
Published in Blood (21.05.2009)
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Journal Article
The P140K mutant of human O(6)-methylguanine-DNA-methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator O(6)-(4-bromothenyl)guanine
Woolford, Lorna B, Southgate, Thomas D, Margison, Geoffrey P, Milsom, Michael D, Fairbairn, Leslie J
Published in The journal of gene medicine (01.01.2006)
Published in The journal of gene medicine (01.01.2006)
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Journal Article
High transduction efficiency of circulating first trimester fetal mesenchymal stem cells: potential targets for in utero ex vivo gene therapy
Campagnoli, Cesare, Bellantuono, Ilaria, Kumar, Sailesh, Fairbairn, Leslie J., Roberts, Irene, Fisk, Nicholas M.
Published in BJOG : an international journal of obstetrics and gynaecology (01.08.2002)
Published in BJOG : an international journal of obstetrics and gynaecology (01.08.2002)
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Journal Article
Radioprotective gene therapy through retroviral expression of manganese superoxide dismutase
Southgate, Thomas D., Sheard, Victoria, Milsom, Michael D., Ward, Timothy H., Mairs, Robert J., Boyd, Marie, Fairbairn, Leslie J.
Published in The journal of gene medicine (01.05.2006)
Published in The journal of gene medicine (01.05.2006)
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Journal Article
Genetic manipulation of drug sensitivity in haematopoietic cells
Southgate, Thomas, Fairbairn, Leslie J.
Published in Expert reviews in molecular medicine (06.08.2004)
Published in Expert reviews in molecular medicine (06.08.2004)
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Journal Article
Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P140K mutant of O6-methylguanine-DNA-methyl transferase
Southgate, Thomas D., Garside, Elloise, Margison, Geoffrey P., Fairbairn, Leslie J.
Published in The journal of gene medicine (01.08.2006)
Published in The journal of gene medicine (01.08.2006)
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Journal Article
Retrovirally mediated correction of bone marrow–derived mesenchymal stem cells from patients with mucopolysaccharidosis type I
Baxter, Melissa A., Wynn, Robert F., Deakin, Jonathan A., Bellantuono, Ilaria, Edington, Kirsten G., Cooper, Alan, Besley, Guy T.N., Church, Heather J., Wraith, J. Ed, Carr, Trevor F., Fairbairn, Leslie J.
Published in Blood (01.03.2002)
Published in Blood (01.03.2002)
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Journal Article
Total Deletion of in Vivo Telomere Elongation Capacity: An Ambitious but Possibly Ultimate Cure for All Age-Related Human Cancers
DE GREY, AUBREY D. N. J., CAMPBELL, F CHARLES, DOKAL, INDERJEET, FAIRBAIRN, LESLIE J., GRAHAM, GERRY J., JAHODA, COLIN A. B., PORTERG, ANDREW C. G.
Published in Annals of the New York Academy of Sciences (01.06.2004)
Published in Annals of the New York Academy of Sciences (01.06.2004)
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Journal Article
Erratum to “Enhanced in Vivo Selection of Bone Marrow Cells by Retroviral-Mediated Coexpression of Mutant O6-Methylguanine-DNA-methyltransferase and HOXB4”
Milsom, Michael D., Woolford, Lorna B., Margison, Geoffrey P., Humphries, R. Keith, Fairbairn, Leslie J.
Published in Molecular therapy (01.10.2005)
Published in Molecular therapy (01.10.2005)
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Journal Article
Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O6-methylguanine-DNA-methyltransferase and HOXB4
Milsom, Michael D, Woolford, Lorna B, Margison, Geoffrey P, Humphries, R Keith, Fairbairn, Leslie J
Published in Molecular therapy (01.11.2004)
Published in Molecular therapy (01.11.2004)
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Journal Article
The P140K mutant of human O6-methylguanine-DNA-methyltransferase (MGMT) confers resistance in vitro and in vivo to temozolomide in combination with the novel MGMT inactivator O6-(4-bromothenyl)guanine
Woolford, Lorna B., Southgate, Thomas D., Margison, Geoffrey P., Milsom, Michael D., Fairbairn, Leslie J.
Published in The journal of gene medicine (01.01.2006)
Published in The journal of gene medicine (01.01.2006)
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Journal Article
Prospects for gene therapy using haemopoietic stem cells
Fairbairn, Leslie J, Ewing, Joanne C
Published in Best practice & research. Clinical haematology (01.12.2001)
Published in Best practice & research. Clinical haematology (01.12.2001)
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Journal Article
Enhancing hemopoietic drug resistance: a rationale for reconsidering the clinical use of mitozolomide
Fairbairn, L J, Chinnasamy, N, Lashford, L S, Chinnasamy, D, Rafferty, J A
Published in Cancer gene therapy (01.02.2000)
Published in Cancer gene therapy (01.02.2000)
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Journal Article