OMTX705, a Novel FAP-Targeting ADC Demonstrates Activity in Chemotherapy and Pembrolizumab-Resistant Solid Tumor Models
Fabre, Myriam, Ferrer, Cristina, Domínguez-Hormaetxe, Saioa, Bockorny, Bruno, Murias, Laura, Seifert, Oliver, Eisler, Stephan A, Kontermann, Roland E, Pfizenmaier, Klaus, Lee, So Young, Vivanco, María dM, López-Casas, Pedro P, Perea, Sofia, Abbas, Muhammad, Richter, Wolfgang, Simon, Laureano, Hidalgo, Manuel
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells
Martínez-Estrada, Ofelia M, Cullerés, Albert, Soriano, Francesc X, Peinado, Hector, Bolós, Victoria, Martínez, Fernando O, Reina, Manuel, Cano, Amparo, Fabre, Myriam, Vilaró, Senén
Published in Biochemical journal (01.03.2006)
Published in Biochemical journal (01.03.2006)
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Aberrant development of hippocampal circuits and altered neural activity in netrin 1-deficient mice
Barallobre, M J, Del Río, J A, Alcántara, S, Borrell, V, Aguado, F, Ruiz, M, Carmona, M A, Martín, M, Fabre, M, Yuste, R, Tessier-Lavigne, M, Soriano, E
Published in Development (Cambridge) (15.11.2000)
Published in Development (Cambridge) (15.11.2000)
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The 18q21 region in colorectal and pancreatic cancer: independent loss of DCC and DPC4 expression
Barberá, Victor M, Martı́n, Mercè, Mariñoso, Luisa, Munné, Assumpta, Carrato, Alfredo, Real, Francisco X, Fabre, Myriam
Published in Biochimica et biophysica acta (18.10.2000)
Published in Biochimica et biophysica acta (18.10.2000)
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Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma
Puerto-Camacho, Pilar, Amaral, Ana Teresa, Lamhamedi-Cherradi, Salah-Eddine, Menegaz, Brian A, Castillo-Ecija, Helena, Ordóñez, José Luis, Domínguez, Saioa, Jordan-Perez, Carmen, Diaz-Martin, Juan, Romero-Pérez, Laura, Lopez-Alvarez, Maria, Civantos-Jubera, Gema, Robles-Frías, María José, Biscuola, Michele, Ferrer, Cristina, Mora, Jaume, Cuglievan, Branko, Schadler, Keri, Seifert, Oliver, Kontermann, Roland, Pfizenmaier, Klaus, Simón, Laureano, Fabre, Myriam, Carcaboso, Ángel M, Ludwig, Joseph A, de Álava, Enrique
Published in Clinical cancer research (01.04.2019)
Published in Clinical cancer research (01.04.2019)
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Targeting carcinoma‐associated mesothelial cells with antibody–drug conjugates in ovarian carcinomatosis
Pascual‐Antón, Lucía, Sandoval, Pilar, González‐Mateo, Guadalupe T, Kopytina, Valeria, Tomero‐Sanz, Henar, Arriero‐País, Eva María, Jiménez‐Heffernan, José Antonio, Fabre, Myriam, Egaña, Isabel, Ferrer, Cristina, Simón, Laureano, González‐Cortijo, Lucía, Sainz de la Cuesta, Ricardo, López‐Cabrera, Manuel
Published in The Journal of pathology (01.10.2023)
Published in The Journal of pathology (01.10.2023)
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Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia
Villanueva, Lorea, Perez-Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, Sebastian, Eider San, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, María, Setien, Fernando, Moutinho, Catia, Villanueva, Alberto, González-Barca, Eva, Muncunill, Josep, Navarro, José Tomás, Piris, Miguel Ángel, Cossio, Fernando, Esteller, Manel
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia
Perez-Salvia, Montserrat, Eneko, Aldaba, Yosu, Vara, Myriam, Fabre, Cristina, Ferrer, Carme, Masdeu, Aizpea, Zubia, Eider, San Sebastian, Dorleta, Otaegui, Pere, Llinàs-Arias, Margalida, Rosselló-Tortella, Maria, Berdasco, Fernando, Setien, Catia, Moutinho, Alberto, Villanueva, González-Barca, Eva, Muncunill, Josep, Navarro, Jose Tomas, Piris, Miguel Angel, Fernando, Cossio, Esteller, Manel
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma
Pérez Salvia, Montserrat, Aldaba, Eneko, Vara, Yosu, Fabre, Myriam, Ferrer, Cristina, Masdeu, Carme, Zubia, Aizpea, San Sebastian, Eider, Otaegui, Dorleta, Llinàs-Arias, Pere, Rosselló-Tortella, Margalida, Berdasco, María, Moutinho, Cátia, Setién, Fernando, Villanueva Garatachea, Alberto, González Barca, Eva, Muncunill, Josep, Navarro, José-Tomás, Piris, Miguel A, Cossio, Fernando P, Esteller, Manel
Published in Haematologica (Roma) (01.11.2018)
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Published in Haematologica (Roma) (01.11.2018)
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Erythropoietin protects the in vitro blood-brain barrier against VEGF-induced permeability
Martínez-Estrada, Ofelia María, Rodríguez-Millán, Elisabeth, González-de Vicente, Esther, Reina, Manuel, Vilaró, Senén, Fabre, Myriam
Published in The European journal of neuroscience (01.11.2003)
Published in The European journal of neuroscience (01.11.2003)
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ANTIBODY-DRUG CONJUGATES AND IMMUNOTOXINS
KONTERMANN ROLAND, FERRER CRISTINA, PFIZENMAIER KLAUS, FABRE MYRIAM, SIMON LAUREANO
Year of Publication 30.09.2016
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Year of Publication 30.09.2016
Patent
ANTIBODY-DRUG CONJUGATES AND IMMUNOTOXINS
KONTERMANN ROLAND, FERRER CRISTINA, PFIZENMAIER KLAUS, FABRE MYRIAM, SIMON LAUREANO
Year of Publication 30.09.2016
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Year of Publication 30.09.2016
Patent
An in vitro tool to assess cytochrome P450 drug biotransformation-dependent cytotoxicity in engineered HepG2 cells generated by using adenoviral vectors
Lahoz, Agustín, Vilà, Maya R., Fabre, Myriam, Miquel, Josep M., Rivas, Manuel, Maines, Jessica, Castell, José V., Gómez-Lechón, M. José
Published in Toxicology in vitro (01.06.2013)
Published in Toxicology in vitro (01.06.2013)
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DCC regulates cell adhesion in human colon cancer derived HT-29 cells and associates with ezrin
Martín, Mercè, Simon-Assmann, Patricia, Kedinger, Michèle, Martin, Marianne, Mangeat, Paul, Real, Francisco X., Fabre, Myriam
Published in European journal of cell biology (01.08.2006)
Published in European journal of cell biology (01.08.2006)
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Database of IC50 Values and Principal Component Analysis of Results from Six Basal Cytotoxicity Assays, for Use in the Modelling of the In Vivo and In Vitro Data of the EU ACuteTox Project
Clothier, Richard, Dierickx, Paul, Lakhanisky, Thaly, Fabre, Myriam, Betanzos, Monica, Curren, Rodger, Sjöström, Michael, Raabe, Hans, Bourne, Nicola, Hernandez, Vanessa, Mainez, Jessica, Owen, Monika, Watts, Sarah, Anthonissen, Roel
Published in Alternatives to laboratory animals (01.11.2008)
Published in Alternatives to laboratory animals (01.11.2008)
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ANTIBODY-DRUG CONJUGATES AND IMMUNOTOXINS
PFIZENMAIER, KLAUS, KONTERMANN, ROLAND, FERRER, CRISTINA, SIMON, LAUREANO, FABRE, MYRIAM
Year of Publication 03.01.2023
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Year of Publication 03.01.2023
Patent
The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells1
Martínez-Estrada, Ofelia M., Cullerés, Albert, Soriano, Francesc X., Peinado, Hector, Bolós, Victoria, Martínez, Fernando O., Reina, Manuel, Cano, Amparo, Fabre, Myriam, Vilaró, Senén
Published in Biochemical journal (10.02.2006)
Published in Biochemical journal (10.02.2006)
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Journal Article
ANTIBODY-DRUG CONJUGATES AND IMMUNOTOXINS
PFIZENMAIER, KLAUS, KONTERMANN, ROLAND, FERRER, CRISTINA, SIMON, LAUREANO, FABRE, MYRIAM
Year of Publication 13.09.2022
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Year of Publication 13.09.2022
Patent
Polypodium leucotomos extract: Antioxidant activity and disposition
Gombau, L., García, F., Lahoz, A., Fabre, Myriam, Roda-Navarro, P., Majano, P., Alonso-Lebrero, J.L., Pivel, J.P., Castell, J.V., Gómez-Lechon, M.J., González, S.
Published in Toxicology in vitro (01.06.2006)
Published in Toxicology in vitro (01.06.2006)
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FAP-TARGETED ANTIBODY-DRUG CONJUGATES
FERRER, Cristina, MORENO, Ruiz Pablo, SIMON, Laureano, GARCIA, Ribas Ignacio, FABRE, Myriam
Year of Publication 01.02.2024
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Year of Publication 01.02.2024
Patent