Comprehensive mutational profiling in advanced systemic mastocytosis
Schwaab, Juliana, Schnittger, Susanne, Sotlar, Karl, Walz, Christoph, Fabarius, Alice, Pfirrmann, Markus, Kohlmann, Alexander, Grossmann, Vera, Meggendorfer, Manja, Horny, Hans-Peter, Valent, Peter, Jawhar, Mohamad, Teichmann, Martina, Metzgeroth, Georgia, Erben, Philipp, Ernst, Thomas, Hochhaus, Andreas, Haferlach, Torsten, Hofmann, Wolf-Karsten, Cross, Nicholas C.P., Reiter, Andreas
Published in Blood (03.10.2013)
Published in Blood (03.10.2013)
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Deep Molecular Response Is Reached by the Majority of Patients Treated With Imatinib, Predicts Survival, and Is Achieved More Quickly by Optimized High-Dose Imatinib: Results From the Randomized CML-Study IV
HEHLMANN, Rüdiger, MÜLLER, Martin C, SCHNITTGER, Susanne, EINSELE, Hermann, DENGLER, Jolanta, FALGE, Christiane, KANZ, Lothar, NEUBAUER, Andreas, KNEBA, Michael, STEGELMANN, Frank, PFREUNDSCHUH, Michael, WALLER, Cornelius F, LAUSEKER, Michael, SPIEKERMANN, Karsten, BAERLOCHER, Gabriela M, EHNINGER, Gerhard, HEIM, Dominik, HEIMPEL, Hermann, NERL, Christoph, KRAUSE, Stefan W, HOSSFELD, Dieter K, KOLB, Hans-Jochem, HASFORD, Joerg, HANFSTEIN, Benjamin, SAUSSELE, Susanne, HOCHHAUS, Andreas, FABARIUS, Alice, SCHREIBER, Annette, PROETEL, Ulrike, PLETSCH, Nadine, PFIRRMANN, Markus, HAFERLACH, Claudia
Published in Journal of clinical oncology (10.02.2014)
Published in Journal of clinical oncology (10.02.2014)
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Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis
Lübke, Johannes, Naumann, Nicole, Kluger, Sebastian, Schwaab, Juliana, Metzgeroth, Georgia, Evans, Erica, Gardino, Alexandra K, Lengauer, Christoph, Hofmann, Wolf-Karsten, Fabarius, Alice, Cross, Nicholas C P, Reiter, Andreas, Jawhar, Mohamad
Published in Leukemia (01.05.2019)
Published in Leukemia (01.05.2019)
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First report on establishment and characterization of a carcinosarcoma tumour cell line model of the bladder
Eberhard, Johannes, Hirsch, Daniela, Schilling, Oliver, Dirks, Wilhelm G, Guo, Feng, Fabarius, Alice, Rückert, Felix, Reißfelder, Christoph, Hohenberger, Peter, Pallavi, Prama
Published in Scientific reports (16.03.2021)
Published in Scientific reports (16.03.2021)
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Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure
Mossner, Maximilian, Jann, Johann-Christoph, Wittig, Janina, Nolte, Florian, Fey, Stephanie, Nowak, Verena, Obländer, Julia, Pressler, Jovita, Palme, Iris, Xanthopoulos, Christina, Boch, Tobias, Metzgeroth, Georgia, Röhl, Henning, Witt, Stephanie H., Dukal, Helene, Klein, Corinna, Schmitt, Steffen, Gelß, Patrick, Platzbecker, Uwe, Balaian, Ekaterina, Fabarius, Alice, Blum, Helmut, Schulze, Torsten J., Meggendorfer, Manja, Haferlach, Claudia, Trumpp, Andreas, Hofmann, Wolf-Karsten, Medyouf, Hind, Nowak, Daniel
Published in Blood (01.09.2016)
Published in Blood (01.09.2016)
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The clinical and molecular diversity of mast cell leukemia with or without associated hematologic neoplasm
Jawhar, Mohamad, Schwaab, Juliana, Meggendorfer, Manja, Naumann, Nicole, Horny, Hans-Peter, Sotlar, Karl, Haferlach, Torsten, Schmitt, Karla, Fabarius, Alice, Valent, Peter, Hofmann, Wolf-Karsten, Cross, Nicholas C P, Metzgeroth, Georgia, Reiter, Andreas
Published in Haematologica (Roma) (01.06.2017)
Published in Haematologica (Roma) (01.06.2017)
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Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV
Fabarius, Alice, Leitner, Armin, Hochhaus, Andreas, Müller, Martin C., Hanfstein, Benjamin, Haferlach, Claudia, Göhring, Gudrun, Schlegelberger, Brigitte, Jotterand, Martine, Reiter, Andreas, Jung-Munkwitz, Susanne, Proetel, Ulrike, Schwaab, Juliana, Hofmann, Wolf-Karsten, Schubert, Jörg, Einsele, Hermann, Ho, Anthony D., Falge, Christiane, Kanz, Lothar, Neubauer, Andreas, Kneba, Michael, Stegelmann, Frank, Pfreundschuh, Michael, Waller, Cornelius F., Spiekermann, Karsten, Baerlocher, Gabriela M., Lauseker, Michael, Pfirrmann, Markus, Hasford, Joerg, Saussele, Susanne, Hehlmann, Rüdiger
Published in Blood (22.12.2011)
Published in Blood (22.12.2011)
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A clinical, morphological and molecular study of 70 patients with gastrointestinal involvement in systemic mastocytosis
Lübke, Johannes, Naumann, Nicole, Hoffmann, Oliver, Horny, Hans-Peter, Sotlar, Karl, Rudelius, Martina, Metzgeroth, Georgia, Fabarius, Alice, Hofmann, Wolf-Karsten, Reiter, Andreas, Schwaab, Juliana
Published in Scientific reports (06.01.2024)
Published in Scientific reports (06.01.2024)
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DNA Damage and DNA Damage Response in Chronic Myeloid Leukemia
Popp, Henning D, Kohl, Vanessa, Naumann, Nicole, Flach, Johanna, Brendel, Susanne, Kleiner, Helga, Weiss, Christel, Seifarth, Wolfgang, Saussele, Susanne, Hofmann, Wolf-Karsten, Fabarius, Alice
Published in International journal of molecular sciences (11.02.2020)
Published in International journal of molecular sciences (11.02.2020)
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Diagnostic performance of the molecular BCR-ABL1 monitoring system may impact on inclusion of CML patients in stopping trials
Spiess, Birgit, Rinaldetti, Sébastien, Naumann, Nicole, Galuschek, Norbert, Kossak-Roth, Ute, Wuchter, Patrick, Tarnopolscaia, Irina, Rose, Diana, Voskanyan, Astghik, Fabarius, Alice, Hofmann, Wolf-Karsten, Saußele, Susanne, Seifarth, Wolfgang
Published in PloS one (21.03.2019)
Published in PloS one (21.03.2019)
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An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis
Riffel, Philipp, Schwaab, Juliana, Lutz, Christopher, Naumann, Nicole, Metzgeroth, Georgia, Fabarius, Alice, Schoenberg, Stefan O., Hofmann, Wolf-Karsten, Valent, Peter, Reiter, Andreas, Jawhar, Mohamad
Published in Journal of cancer research and clinical oncology (01.04.2020)
Published in Journal of cancer research and clinical oncology (01.04.2020)
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Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies
Xu, Qingyu, Streuer, Alexander, Jann, Johann-Christoph, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Sens-Albert, Carla, Rapp, Felicitas, Wolf, Julia, Nowak, Verena, Weimer, Nadine, Obländer, Julia, Palme, Iris, Kuzina, Mariia, Jawhar, Ahmed, Darwich, Ali, Weis, Cleo-Aron, Marx, Alexander, Wuchter, Patrick, Costina, Victor, Jäger, Evelyn, Sperk, Elena, Neumaier, Michael, Fabarius, Alice, Metzgeroth, Georgia, Nolte, Florian, Steiner, Laurenz, Levkin, Pavel A, Jawhar, Mohamad, Hofmann, Wolf-Karsten, Riabov, Vladimir, Nowak, Daniel
Published in Nature communications (17.03.2023)
Published in Nature communications (17.03.2023)
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Distinct characteristics of e13a2 versus e14a2 BCR-ABL1 driven chronic myeloid leukemia under first-line therapy with imatinib
Hanfstein, Benjamin, Lauseker, Michael, Hehlmann, Rüdiger, Saussele, Susanne, Erben, Philipp, Dietz, Christian, Fabarius, Alice, Proetel, Ulrike, Schnittger, Susanne, Haferlach, Claudia, Krause, Stefan W, Schubert, Jörg, Einsele, Hermann, Hänel, Mathias, Dengler, Jolanta, Falge, Christiane, Kanz, Lothar, Neubauer, Andreas, Kneba, Michael, Stegelmann, Frank, Pfreundschuh, Michael, Waller, Cornelius F, Spiekermann, Karsten, Baerlocher, Gabriela M, Pfirrmann, Markus, Hasford, Joerg, Hofmann, Wolf-Karsten, Hochhaus, Andreas, Müller, Martin C
Published in Haematologica (Roma) (01.09.2014)
Published in Haematologica (Roma) (01.09.2014)
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KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis
Jawhar, Mohamad, Döhner, Konstanze, Kreil, Sebastian, Schwaab, Juliana, Shoumariyeh, Khalid, Meggendorfer, Manja, Span, Lambert L F, Fuhrmann, Stephan, Naumann, Nicole, Horny, Hans-Peter, Sotlar, Karl, Kubuschok, Boris, von Bubnoff, Nikolas, Spiekermann, Karsten, Heuser, Michael, Metzgeroth, Georgia, Fabarius, Alice, Klein, Stefan, Hofmann, Wolf-Karsten, Kluin-Nelemans, Hanneke C, Haferlach, Torsten, Döhner, Hartmut, Cross, Nicholas C P, Sperr, Wolfgang R, Valent, Peter, Reiter, Andreas
Published in Leukemia (01.05.2019)
Published in Leukemia (01.05.2019)
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Journal Article
Reverse Transcription Can Critically Impact the Diagnostic Outcome of BCR::ABL1 Quantitative Real-Time RT-PCR
Spiess, Birgit, Kleiner, Helga, Tarnopolscaia, Irina, Naumann, Nicole, Fabarius, Alice, Hofmann, Wolf-Karsten, Saussele, Susanne, Seifarth, Wolfgang
Published in Cancers (01.08.2023)
Published in Cancers (01.08.2023)
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Journal Article
Gene Expression Pattern of ESPL1 , PTTG1 and PTTG1IP Can Potentially Predict Response to TKI First-Line Treatment of Patients with Newly Diagnosed CML
Christiani, Eva, Naumann, Nicole, Weiss, Christel, Spiess, Birgit, Kleiner, Helga, Fabarius, Alice, Hofmann, Wolf-Karsten, Saussele, Susanne, Seifarth, Wolfgang
Published in Cancers (08.05.2023)
Published in Cancers (08.05.2023)
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Journal Article
Functional imaging with dual-energy computed tomography for supplementary non-invasive assessment of mast cell burden in systemic mastocytosis
Riffel, Julia, Lübke, Johannes, Naumann, Nicole, Kreil, Sebastian, Metzgeroth, Georgia, Fabarius, Alice, Sotlar, Karl, Horny, Hans-Peter, Jawhar, Mohamad, Overhoff, Daniel, Schoenberg, Stefan, Hofmann, Wolf-Karsten, Henzler, Thomas, Schwaab, Juliana, Reiter, Andreas, Riffel, Philipp
Published in Scientific reports (20.08.2022)
Published in Scientific reports (20.08.2022)
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Journal Article
Adverse Prognostic Impact of the KIT D816V Transcriptional Activity in Advanced Systemic Mastocytosis
Naumann, Nicole, Lübke, Johannes, Baumann, Sofie, Schwaab, Juliana, Hoffmann, Oliver, Kreil, Sebastian, Dangelo, Vito, Reiter, Lukas, Bugert, Peter, Kristensen, Thomas, Sotlar, Karl, Haselmann, Verena, Schneider, Sven, Metzgeroth, Georgia, Weiss, Christel, Popp, Henning D, Fabarius, Alice, Hofmann, Wolf-Karsten, Cross, Nicholas C P, Reiter, Andreas, Jawhar, Mohamad
Published in International journal of molecular sciences (04.03.2021)
Published in International journal of molecular sciences (04.03.2021)
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Journal Article
Separase activity distribution can be a marker of major molecular response and proliferation of CD34+ cells in TKI-treated chronic myeloid leukemia patients
Spiess, Birgit, Kleiner, Helga, Flach, Johanna, Fabarius, Alice, Saussele, Susanne, Hofmann, Wolf-Karsten, Seifarth, Wolfgang
Published in Annals of hematology (01.05.2020)
Published in Annals of hematology (01.05.2020)
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