Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy
Ulbricht, Anna, Eppler, Felix J., Tapia, Victor E., van der Ven, Peter F.M., Hampe, Nico, Hersch, Nils, Vakeel, Padmanabhan, Stadel, Daniela, Haas, Albert, Saftig, Paul, Behrends, Christian, Fürst, Dieter O., Volkmer, Rudolf, Hoffmann, Bernd, Kolanus, Waldemar, Höhfeld, Jörg
Published in Current biology (04.03.2013)
Published in Current biology (04.03.2013)
Get full text
Journal Article
Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance
Arndt, Verena, Dick, Nikolaus, Tawo, Riga, Dreiseidler, Michael, Wenzel, Daniela, Hesse, Michael, Fürst, Dieter O., Saftig, Paul, Saint, Robert, Fleischmann, Bernd K., Hoch, Michael, Höhfeld, Jörg
Published in Current biology (26.01.2010)
Published in Current biology (26.01.2010)
Get full text
Journal Article
Angiotensin‐II type 1 receptor‐mediated Janus kinase 2 activation induces liver fibrosis
Granzow, Michaela, Schierwagen, Robert, Klein, Sabine, Kowallick, Benita, Huss, Sebastian, Linhart, Markus, Mazar, Irela G. Reza, Görtzen, Jan, Vogt, Annabelle, Schildberg, Frank A., Gonzalez‐Carmona, Maria A., Wojtalla, Alexandra, Krämer, Benjamin, Nattermann, Jacob, Siegmund, Sören V., Werner, Nikos, Fürst, Dieter O., Laleman, Wim, Knolle, Percy, Shah, Vijay H., Sauerbruch, Tilman, Trebicka, Jonel
Published in Hepatology (Baltimore, Md.) (01.07.2014)
Published in Hepatology (Baltimore, Md.) (01.07.2014)
Get full text
Journal Article
Force-induced dephosphorylation activates the cochaperone BAG3 to coordinate protein homeostasis and membrane traffic
Ottensmeyer, Judith, Esch, Alessandra, Baeta, Henrique, Sieger, Sandro, Gupta, Yamini, Rathmann, Maximilian F., Jeschke, Andreas, Jacko, Daniel, Schaaf, Kirill, Schiffer, Thorsten, Rahimi, Bahareh, Lövenich, Lukas, Sisto, Angela, van der Ven, Peter F.M., Fürst, Dieter O., Haas, Albert, Bloch, Wilhelm, Gehlert, Sebastian, Hoffmann, Bernd, Timmerman, Vincent, Huesgen, Pitter F., Höhfeld, Jörg
Published in Current biology (23.09.2024)
Published in Current biology (23.09.2024)
Get full text
Journal Article
246th ENMC International Workshop: Protein aggregate myopathies 24–26 May 2019, Hoofddorp, The Netherlands
Olivé, Montse, Winter, Lilli, Fürst, Dieter O., Schröder, Rolf, Behin, Anthony, Breukel, Alexandra, Brumhard, Matthias, Bryson-Richardson, Robert, Claeys, Kristl, Ferreiro, Ana, Fürst, Dieter, Goebel, Hans H., Gupta, Vandana, Kley, Rudolf, Mankodi, Ami, Noguchi, Satoru, Oldfors, Anders, Olivé, Montse, Schröder, Rolf, Selcen, Duygu, Timmerman, Vincent, Udd, Bjarne, Walter, Maggie, Weihl, Conrad, Wiche, Gerhard, Winter, Lilly
Published in Neuromuscular disorders : NMD (01.02.2021)
Published in Neuromuscular disorders : NMD (01.02.2021)
Get full text
Journal Article
Conference Proceeding
Filamin C-related myopathies: pathology and mechanisms
Fürst, Dieter O., Goldfarb, Lev G., Kley, Rudolf A., Vorgerd, Matthias, Olivé, Montse, van der Ven, Peter F. M.
Published in Acta neuropathologica (01.01.2013)
Published in Acta neuropathologica (01.01.2013)
Get full text
Journal Article
Molecular basis of F-actin regulation and sarcomere assembly via myotilin
Kostan, Julius, Pavšič, Miha, Puž, Vid, Schwarz, Thomas C, Drepper, Friedel, Molt, Sibylle, Graewert, Melissa Ann, Schreiner, Claudia, Sajko, Sara, van der Ven, Peter F M, Onipe, Adekunle, Svergun, Dmitri I, Warscheid, Bettina, Konrat, Robert, Fürst, Dieter O, Lenarčič, Brigita, Djinović-Carugo, Kristina
Published in PLoS biology (12.04.2021)
Published in PLoS biology (12.04.2021)
Get full text
Journal Article
Maintaining proteostasis under mechanical stress
Höhfeld, Jörg, Benzing, Thomas, Bloch, Wilhelm, Fürst, Dieter O, Gehlert, Sebastian, Hesse, Michael, Hoffmann, Bernd, Hoppe, Thorsten, Huesgen, Pitter F, Köhn, Maja, Kolanus, Waldemar, Merkel, Rudolf, Niessen, Carien M, Pokrzywa, Wojciech, Rinschen, Markus M, Wachten, Dagmar, Warscheid, Bettina
Published in EMBO reports (04.08.2021)
Published in EMBO reports (04.08.2021)
Get full text
Journal Article
Myofibrillar Z-discs Are a Protein Phosphorylation Hot Spot with Protein Kinase C (PKCα) Modulating Protein Dynamics
Reimann, Lena, Wiese, Heike, Leber, Yvonne, Schwäble, Anja N., Fricke, Anna L., Rohland, Anne, Knapp, Bettina, Peikert, Christian D., Drepper, Friedel, van der Ven, Peter F.M., Radziwill, Gerald, Fürst, Dieter O., Warscheid, Bettina
Published in Molecular & cellular proteomics (01.03.2017)
Published in Molecular & cellular proteomics (01.03.2017)
Get full text
Journal Article
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1
Kathage, Barbara, Gehlert, Sebastian, Ulbricht, Anna, Lüdecke, Laura, Tapia, Victor E, Orfanos, Zacharias, Wenzel, Daniela, Bloch, Wilhelm, Volkmer, Rudolf, Fleischmann, Bernd K, Fürst, Dieter O, Höhfeld, Jörg
Published in Biochimica et biophysica acta. Molecular cell research (01.01.2017)
Published in Biochimica et biophysica acta. Molecular cell research (01.01.2017)
Get full text
Journal Article
Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage
Leber, Yvonne, Ruparelia, Avnika A, Kirfel, Gregor, van der Ven, Peter F M, Hoffmann, Bernd, Merkel, Rudolf, Bryson-Richardson, Robert J, Fürst, Dieter O
Published in Human molecular genetics (01.07.2016)
Published in Human molecular genetics (01.07.2016)
Get full text
Journal Article
Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats
Klein, Sabine, Frohn, Franziska, Magdaleno, Fernando, Reker-Smit, Catharina, Schierwagen, Robert, Schierwagen, Irela, Uschner, Frank Erhard, van Dijk, Fransien, Fürst, Dieter O., Djudjaj, Sonja, Boor, Peter, Poelstra, Klaas, Beljaars, Leonie, Trebicka, Jonel
Published in Scientific reports (19.02.2019)
Published in Scientific reports (19.02.2019)
Get full text
Journal Article
Proteomic and morphological insights and clinical presentation of two young patients with novel mutations of BVES (POPDC1)
Gangfuß, Andrea, Hentschel, Andreas, Heil, Lorena, Gonzalez, Maria, Schönecker, Anne, Depienne, Christel, Nishimura, Anna, Zengeler, Diana, Kohlschmidt, Nicolai, Sickmann, Albert, Schara-Schmidt, Ulrike, Fürst, Dieter O., van der Ven, Peter F.M., Hahn, Andreas, Roos, Andreas, Schänzer, Anne
Published in Molecular genetics and metabolism (01.07.2022)
Published in Molecular genetics and metabolism (01.07.2022)
Get full text
Journal Article
Filamin-A-interacting protein 1 (FILIP1) is a dual compartment protein linking myofibrils and microtubules during myogenic differentiation and upon mechanical stress
Grande, Valentina, Schuld, Julia, van der Ven, Peter F. M., Gruss, Oliver J., Fürst, Dieter O.
Published in Cell and tissue research (01.07.2023)
Published in Cell and tissue research (01.07.2023)
Get full text
Journal Article
Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function
Unger, Andreas, Beckendorf, Lisa, Böhme, Pierre, Kley, Rudolf, von Frieling-Salewsky, Marion, Lochmüller, Hanns, Schröder, Rolf, Fürst, Dieter O, Vorgerd, Matthias, Linke, Wolfgang A
Published in Acta neuropathologica communications (15.09.2017)
Published in Acta neuropathologica communications (15.09.2017)
Get full text
Journal Article
Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats
Klein, Sabine, Klösel, Jeremias, Schierwagen, Robert, Körner, Christian, Granzow, Michaela, Huss, Sebastian, Mazar, Irela Gretchen Reza, Weber, Susanne, van den Ven, Peter F M, Pieper-Fürst, Ursula, Fürst, Dieter O, Nattermann, Jacob, Lammert, Frank, Sauerbruch, Tilman, Trebicka, Jonel
Published in Laboratory investigation (01.10.2012)
Published in Laboratory investigation (01.10.2012)
Get full text
Journal Article
Isoform-specific functions of synaptopodin-2 variants in cytoskeleton stabilization and autophagy regulation in muscle under mechanical stress
Lohanadan, Keerthika, Molt, Sibylle, Dierck, Franziska, van der Ven, Peter F.M., Frey, Norbert, Höhfeld, Jörg, Fürst, Dieter O.
Published in Experimental cell research (15.11.2021)
Published in Experimental cell research (15.11.2021)
Get full text
Journal Article
Breaking sarcomeres by in vitro exercise
Orfanos, Zacharias, Gödderz, Markus P. O., Soroka, Ekaterina, Gödderz, Tobias, Rumyantseva, Anastasia, van der Ven, Peter F. M., Hawke, Thomas J., Fürst, Dieter O.
Published in Scientific reports (25.01.2016)
Published in Scientific reports (25.01.2016)
Get full text
Journal Article
First clinical and myopathological description of a myofibrillar myopathy with congenital onset and homozygous mutation in FLNC
Kölbel, Heike, Roos, Andreas, Ven, Peter F. M., Evangelista, Teresinha, Nolte, Kay, Johnson, Katherine, Töpf, Ana, Wilson, Michael, Kress, Wolfram, Sickmann, Albert, Straub, Volker, Kollipara, Laxmikanth, Weis, Joachim, Fürst, Dieter O., Schara, Ulrike
Published in Human mutation (01.09.2020)
Published in Human mutation (01.09.2020)
Get full text
Journal Article
Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance
Molt, Sibylle, Bührdel, John B, Yakovlev, Sergiy, Schein, Peter, Orfanos, Zacharias, Kirfel, Gregor, Winter, Lilli, Wiche, Gerhard, van der Ven, Peter F M, Rottbauer, Wolfgang, Just, Steffen, Belkin, Alexey M, Fürst, Dieter O
Published in Journal of cell science (15.08.2014)
Published in Journal of cell science (15.08.2014)
Get full text
Journal Article