An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development
Shankar, Sunita, Tien, Jean Ching-Yi, Siebenaler, Ronald F, Chugh, Seema, Dommeti, Vijaya L, Zelenka-Wang, Sylvia, Wang, Xiao-Ming, Apel, Ingrid J, Waninger, Jessica, Eyunni, Sanjana, Xu, Alice, Mody, Malay, Goodrum, Andrew, Zhang, Yuping, Tesmer, John J, Mannan, Rahul, Cao, Xuhong, Vats, Pankaj, Pitchiaya, Sethuramasundaram, Ellison, Stephanie J, Shi, Jiaqi, Kumar-Sinha, Chandan, Crawford, Howard C, Chinnaiyan, Arul M
Published in Nature communications (04.06.2020)
Published in Nature communications (04.06.2020)
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Journal Article
Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer
Xiao, Lanbo, Parolia, Abhijit, Qiao, Yuanyuan, Bawa, Pushpinder, Eyunni, Sanjana, Mannan, Rahul, Carson, Sandra E, Chang, Yu, Wang, Xiaoju, Zhang, Yuping, Vo, Josh N, Kregel, Steven, Simko, Stephanie A, Delekta, Andrew D, Jaber, Mustapha, Zheng, Heng, Apel, Ingrid J, McMurry, Lisa, Su, Fengyun, Wang, Rui, Zelenka-Wang, Sylvia, Sasmal, Sanjita, Khare, Leena, Mukherjee, Subhendu, Abbineni, Chandrasekhar, Aithal, Kiran, Bhakta, Mital S, Ghurye, Jay, Cao, Xuhong, Navone, Nora M, Nesvizhskii, Alexey I, Mehra, Rohit, Vaishampayan, Ulka, Blanchette, Marco, Wang, Yuzhuo, Samajdar, Susanta, Ramachandra, Murali, Chinnaiyan, Arul M
Published in Nature (London) (20.01.2022)
Published in Nature (London) (20.01.2022)
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Journal Article
Discovery of LLC0424 as a Potent and Selective in Vivo NSD2 PROTAC Degrader
Liu, Lianchao, Parolia, Abhijit, Liu, Yihan, Hou, Caiyun, He, Tongchen, Qiao, Yuanyuan, Eyunni, Sanjana, Luo, Jie, Li, Chungen, Wang, Yongxing, Zhou, Fengtao, Huang, Weixue, Ren, Xiaomei, Wang, Zhen, Chinnaiyan, Arul M., Ding, Ke
Published in Journal of medicinal chemistry (09.05.2024)
Published in Journal of medicinal chemistry (09.05.2024)
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Journal Article
Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response
Qiao, Yuanyuan, Wotring, Jesse W, Zheng, Yang, Zhang, Charles J, Zhang, Yuping, Jiang, Xia, Pretto, Carla D, Eyunni, Sanjana, Parolia, Abhijit, He, Tongchen, Cheng, Caleb, Cao, Xuhong, Wang, Rui, Su, Fengyun, Ellison, Stephanie J, Wang, Yini, Qin, Jun, Yan, Honghua, Zhou, Qianxiang, Ma, Liandong, Sexton, Jonathan Z, Chinnaiyan, Arul M
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2023)
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Journal Article
NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, Abhijit, Eyunni, Sanjana, Verma, Brijesh Kumar, Young, Eleanor, Liu, Yihan, Liu, Lianchao, George, James, Aras, Shweta, Das, Chandan Kanta, Mannan, Rahul, ur Rasool, Reyaz, Mitchell-Velasquez, Erick, Mahapatra, Somnath, Luo, Jie, Carson, Sandra E., Xiao, Lanbo, Gajjala, Prathibha R., Venkatesh, Sharan, Jaber, Mustapha, Wang, Xiaoju, He, Tongchen, Qiao, Yuanyuan, Pang, Matthew, Zhang, Yuping, Tien, Jean Ching-Yi, Louw, Micheala, Alhusayan, Mohammed, Cao, Xuhong, Su, Fengyun, Tavana, Omid, Hou, Caiyun, Wang, Zhen, Ding, Ke, Chinnaiyan, Arul M., Asangani, Irfan A.
Published in Nature genetics (09.09.2024)
Published in Nature genetics (09.09.2024)
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Journal Article
Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
He, Tongchen, Xiao, Lanbo, Qiao, Yuanyuan, Klingbeil, Olaf, Young, Eleanor, Wu, Xiaoli S., Mannan, Rahul, Mahapatra, Somnath, Redin, Esther, Cho, Hanbyul, Bao, Yi, Kandarpa, Malathi, Ching-Yi Tien, Jean, Wang, Xiaoju, Eyunni, Sanjana, Zheng, Yang, Kim, NamHoon, Zheng, Heng, Hou, Siyu, Su, Fengyun, Miner, Stephanie J., Mehra, Rohit, Cao, Xuhong, Abbineni, Chandrasekhar, Samajdar, Susanta, Ramachandra, Murali, Dhanasekaran, Saravana M., Talpaz, Moshe, Parolia, Abhijit, Rudin, Charles M., Vakoc, Christopher R., Chinnaiyan, Arul M.
Published in Cancer cell (12.08.2024)
Published in Cancer cell (12.08.2024)
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Journal Article
Author Correction: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer
Xiao, Lanbo, Parolia, Abhijit, Qiao, Yuanyuan, Bawa, Pushpinder, Eyunni, Sanjana, Mannan, Rahul, Carson, Sandra E, Chang, Yu, Wang, Xiaoju, Zhang, Yuping, Vo, Josh N, Kregel, Steven, Simko, Stephanie A, Delekta, Andrew D, Jaber, Mustapha, Zheng, Heng, Apel, Ingrid J, McMurry, Lisa, Su, Fengyun, Wang, Rui, Zelenka-Wang, Sylvia, Sasmal, Sanjita, Khare, Leena, Mukherjee, Subhendu, Abbineni, Chandrasekhar, Aithal, Kiran, Bhakta, Mital S, Ghurye, Jay, Cao, Xuhong, Navone, Nora M, Nesvizhskii, Alexey I, Mehra, Rohit, Vaishampayan, Ulka, Blanchette, Marco, Wang, Yuzhuo, Samajdar, Susanta, Ramachandra, Murali, Chinnaiyan, Arul M
Published in Nature (London) (09.05.2024)
Published in Nature (London) (09.05.2024)
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Journal Article
Abstract 94: Role of Argonaute 2 in oncogene induced senescence in a pancreatic cancer mouse model
Chugh, Seema, Tien, Jean C., Siebenaler, Ronald F., Dommeti, Vijaya L., Wang, Sylvia Z., Eyunni, Sanjana, Juckette, Kristin M., Wang, Lisha, Shankar, Sunita, Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract A056: AR/FOXA1-mediated active gene repression as a mechanism of prostate carcinogenesis
Eyunni, Sanjana, Parolia, Abhijit, Young, Eleanor, George, James, Jaber, Mustapha, Xiao, Lanbo, Su, Fengyun, Wang, Rui, Cao, Xuhong, Chinnaiyan, Arul
Published in Cancer research (Chicago, Ill.) (02.06.2023)
Published in Cancer research (Chicago, Ill.) (02.06.2023)
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Journal Article
Abstract 2577: AGO2 interaction limits wild type RAS activation yet essential for disease progression in oncogenic KRAS driven cancers
Shankar, Sunita, Tien, Jean Ching-Yi, Siebenaler, Ronald F., Chugh, Seema, Dommeti, Vijaya L., Zelenka-Wang, Sylvia, Waninger, Jessica, Juckette, Kristin M., Wang, Xiao-Ming, Eyunni, Sanjana, Goodrum, Andrew, Zhang, Yuping, Apel, Ingrid J., Siddiqui, Javed, Cao, Xuhong, Shi, Jiaqi, Pitchiaya, Sethuramsundaram, Kumar-Sinha, Chandan, Crawford, Howard C., Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 6602: Targeting the SWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies
Xiao, Lanbo, He, Tongchen, Klingbeil, Olaf, Eleanor, Young, Wu, Xiaoli, Qiao, Yuanyuan, Parolia, Abhijit, Eyunni, Sanjana, Mannan, Rahul, Mahapatra, Somnath, Kim, NamHoon, Zheng, Heng, Su, Fengyun, Cao, Xuhong, Samajdar, Susanta, Ramachandra, Murali, Vakoc, Christopher R., Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract A20: An essential role for Argonaute 2 in mouse models of KRAS driven cancers
Shankar, Sunita, Tien, Jean Ching-Yi, Siebenaler, Ronald F., Dommeti, Vijaya L., Zelenka-Wang, Sylvia, Waninger, Jessica, Wang, Xiao-Ming, Juckette, Kristin M., Xu, Alice, Chugh, Seema, Mody, Malay, Eyunni, Sanjana, Goodrum, Andrew, Tsaloff, Grace, Zhang, Yuping, Apel, Ingrid J., Wang, Lisha, Siddiqui, Javed, Smith, Richard D., Carlson, Heather A., Tesmer, John, Cao, Xuhong, Shi, Jiaqi, Kumar-Sinha, Chandan, Chinnaiyan, Arul M.
Published in Molecular cancer research (01.05.2020)
Published in Molecular cancer research (01.05.2020)
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Journal Article
Abstract 957: An essential role for Argonaute 2 in mouse models of KRAS- driven cancers
Shankar, Sunita, Tien, Jean Ching-Yi, Siebenaler, Ronald F., Dommeti, Vijaya L., Zelenka-Wang, Sylvia, Waninger, Jessica, Juckette, Kristin M., Xu, Alice, Wang, Xiao-Ming, Chugh, Seema, Mody, Malay, Eyunni, Sanjana, Goodrum, Andrew, Tsaloff, Grace, Zhang, Yuping, Apel, Ingrid J., Siddiqui, Javed, Smith, Richard D., Carlson, Heather A., Tesmer, John, Cao, Xuhong, Shi, Jiaqi, Kumar-Sinha, Chandan, Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 1433: FOXA1 alterations distinctively drive prostate tumorigenesis or therapy resistance in mice
Eyunni, Sanjana, Parolia, Abhijit, Young, Eleanor, George, James Matthew, Mannan, Rahul, Carson, Sandra E., Zhang, Yuping, Tien, Jean, Jaber, Mustapha, Luo, Jie, Pang, Matthew, Mehra, Rohit, Cao, Xuhong, Su, Fengyun, Wang, Rui, Cieslik, Marcin, Lee, Dong Kee, Xu, Jianming, Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract A055: NSD2 is a requisite and targetable subunit of the AR/FOXA1 neo -enhanceosome complex in prostate cancer cells
Parolia, Abhijit, Verma, Brijesh K., Eyunni, Sanjana, Aras, Sweta, Carson, Sandra E., Young, Eleanor, Das, Chandan K., George, James M., Rasool, Reyaz ur, Gajjala, Prathibha, Alhusayan, Mohammed, Mitchell-Velasquez, Erick, Xiao, Lanbo, Luo, Jie, Jaber, Mustapha, Cao, Xuhong, Su, Fengyun, Wang, Rui, Liu, Lianchao, Wang, Zhen, Ding, Ke, Chinnaiyan, Arul M., Asangani, Irfan
Published in Cancer research (Chicago, Ill.) (02.06.2023)
Published in Cancer research (Chicago, Ill.) (02.06.2023)
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Journal Article
Abstract 3592: Targeting SWI/SNF ATPases in enhancer-addicted human cancers
Parolia, Abhijit, Xiao, Lanbo, Qiao, Yuanyuan, Bawa, Pushpinder, Eyunni, Sanjana, Young, Eleanor, Mannan, Rahul, Carson, Sandra E., Chang, Yu, Zhang, Yuping, George, James, Jaber, Mustapha, Su, Fengyun, Wang, Rui, Sasmal, Sanjita, Khare, Leena, Mukerjee, Subhendu, AbbinenI, Chandrasekhar, Aithal, Kiran, Cao, Xuhong, Wang, Yuzhuo, Samajdar, Susanta, Ramachandra, Murali, Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract 5469: Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer
Xiao, Lanbo, Parolia, Abhijit, Qiao, Yuanyuan, Pushpinder, Pushpinder Bawa, Eyunni, Sanjana, Mannan, Rahul, Carson, Sandra E., Chang, Yu, Wang, Xiaoju, Zhang, Yuping, Vo, Josh, Kregel, Steven, Simko, Stephanie A., Delekta, Andrew D., Jaber, Mustapha, Zheng, Heng, Apel, Ingrid, McMurry, Lisa, Su, Fengyun, Wang, Rui, Wang, Sylvia, Sasmal, Sanjita, Satyam, Leena K., Mukherjee, Subhendu, AbbinenI, Chandrasekhar, Aithal, Kiran, Bhakta, Mital S., Ghurye, Jay, Cao, Xuhong, Navone, Nora M., Nesvizhskii, Alexey, Mehra, Rohit, Vaishampayan, Ulka, Blanchette, Marco, Wang, Yuzhuo, Samajdar, Susanta, Ramachandra, Murali, Chinnaiyan, Arul M.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer
Luo, Jie, Chen, Zhixiang, Qiao, Yuanyuan, Tien, Jean Ching-Yi, Young, Eleanor, Mannan, Rahul, Mahapatra, Somnath, He, Tongchen, Eyunni, Sanjana, Zhang, Yuping, Zheng, Yang, Su, Fengyun, Cao, Xuhong, Wang, Rui, Cheng, Yunhui, Seri, Rithvik, George, James, Shahine, Miriam, Miner, Stephanie J, Vaishampayan, Ulka, Wang, Mi, Wang, Shaomeng, Parolia, Abhijit, Chinnaiyan, Arul M
Published in bioRxiv : the preprint server for biology (23.05.2024)
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Published in bioRxiv : the preprint server for biology (23.05.2024)
Journal Article
Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies
He, Tongchen, Xiao, Lanbo, Qiao, Yuanyuan, Klingbeil, Olaf, Young, Eleanor, Wu, Xiaoli S, Mannan, Rahul, Mahapatra, Somnath, Eyunni, Sanjana, Tien, Jean Ching-Yi, Wang, Xiaoju, Zheng, Yang, Kim, NamHoon, Zheng, Heng, Hou, Siyu, Su, Fengyun, Miner, Stephanie J, Mehra, Rohit, Cao, Xuhong, Abbineni, Chandrasekhar, Samajdar, Susanta, Ramachandra, Murali, Parolia, Abhijit, Vakoc, Christopher R, Chinnaiyan, Arul M
Published in bioRxiv (24.05.2024)
Published in bioRxiv (24.05.2024)
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Journal Article
NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis
Parolia, Abhijit, Eyunni, Sanjana, Verma, Brijesh Kumar, Young, Eleanor, Liu, Lianchao, George, James, Aras, Shweta, Das, Chandan Kanta, Mannan, Rahul, Rasool, Reyaz Ur, Luo, Jie, Carson, Sandra E, Mitchell-Velasquez, Erick, Liu, Yihan, Xiao, Lanbo, Gajjala, Prathibha R, Jaber, Mustapha, Wang, Xiaoju, He, Tongchen, Qiao, Yuanyuan, Pang, Matthew, Zhang, Yuping, Alhusayan, Mohammed, Cao, Xuhong, Tavana, Omid, Hou, Caiyun, Wang, Zhen, Ding, Ke, Chinnaiyan, Arul M, Asangani, Irfan A
Published in bioRxiv (29.03.2024)
Published in bioRxiv (29.03.2024)
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