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Population pharmacokinetics and exposure–response analyses of safety (ARIA‐E and isolated ARIA‐H) of lecanemab in subjects with early Alzheimer's disease
Majid, Oneeb, Cao, Youfang, Willis, Brian A., Hayato, Seiichi, Takenaka, Osamu, Lalovic, Bojan, Sreerama Reddy, Sree Harsha, Penner, Natasha, Reyderman, Larisa, Yasuda, Sanae, Hussein, Ziad
Published in CPT: pharmacometrics and systems pharmacology (01.12.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.12.2024)
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Dose Finding of Lenvatinib in Subjects With Advanced Hepatocellular Carcinoma Based on Population Pharmacokinetic and Exposure–Response Analyses
Tamai, Toshiyuki, Hayato, Seiichi, Hojo, Seiichiro, Suzuki, Takuya, Okusaka, Takuji, Ikeda, Kenji, Kumada, Hiromitsu
Published in Journal of clinical pharmacology (01.09.2017)
Published in Journal of clinical pharmacology (01.09.2017)
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Exposure‐Response Analyses for Upadacitinib Efficacy in Subjects With Atopic Dermatitis—Analyses of Phase 2b Study to Support Selection of Phase 3 Doses
Mohamed, Mohamed‐Eslam F., Gopalakrishnan, Sathej, Teixeira, Henrique D., Othman, Ahmed A.
Published in Journal of clinical pharmacology (01.05.2021)
Published in Journal of clinical pharmacology (01.05.2021)
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Model‐based population pharmacokinetic and exposure response analyses for safety and efficacy of nivolumab as adjuvant treatment in subjects with resected oesophageal or gastroesophageal junction cancer
Zhao, Yue, Tsujimoto, Akihide, Ide, Takafumi, Zhang, Jenny, Feng, Yan, Gao, Ling, Bello, Akintunde, Roy, Amit
Published in British journal of clinical pharmacology (01.11.2024)
Published in British journal of clinical pharmacology (01.11.2024)
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Pharmacodynamic modelling and exposure–response assessment of inebilizumab in subjects with neuromyelitis optica spectrum disorders
Yan, Li, Wang, Bing, She, Dewei, Mitchell, Ben, Criste, Ryan, Cimbora, Daniel, Katz, Eliezer, Rees, William A.
Published in British journal of clinical pharmacology (01.08.2022)
Published in British journal of clinical pharmacology (01.08.2022)
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Pembrolizumab Exposure–Response Assessments Challenged by Association of Cancer Cachexia and Catabolic Clearance
Turner, David C., Kondic, Anna G., Anderson, Keaven M., Robinson, Andrew G., Garon, Edward B., Riess, Jonathan Wesley, Jain, Lokesh, Mayawala, Kapil, Kang, Jiannan, Ebbinghaus, Scot W., Sinha, Vikram, de Alwis, Dinesh P., Stone, Julie A.
Published in Clinical cancer research (01.12.2018)
Published in Clinical cancer research (01.12.2018)
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Exposure‐response relationships for the efficacy and safety of filgotinib and its metabolite GS‐829845 in subjects with rheumatoid arthritis based on phase 2 and phase 3 studies
Meng, Amy, Anderson, Kacey, Nelson, Cara, Ni, Liyun, Chuang, Shu‐Min, Bellanti, Francesco, Chang, Peter, Comisar, Craig, Kearney, Brian P., Bartok, Beatrix, Mathias, Anita
Published in British journal of clinical pharmacology (01.07.2022)
Published in British journal of clinical pharmacology (01.07.2022)
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Diesel Engine Exhaust Exposure, Smoking, and Lung Cancer Subtype Risks. A Pooled Exposure–Response Analysis of 14 Case–Control Studies
Ge, Calvin, Peters, Susan, Olsson, Ann, Portengen, Lützen, Schüz, Joachim, Almansa, Josué, Ahrens, Wolfgang, Bencko, Vladimir, Benhamou, Simone, Boffetta, Paolo, Bueno-de-Mesquita, Bas, Caporaso, Neil, Consonni, Dario, Demers, Paul, Fabiánová, Eleonóra, Fernández-Tardón, Guillermo, Field, John, Forastiere, Francesco, Foretova, Lenka, Guénel, Pascal, Gustavsson, Per, Janout, Vladimir, Jöckel, Karl-Heinz, Karrasch, Stefan, Teresa Landi, Maria, Lissowska, Jolanta, Luce, Danièle, Mates, Dana, McLaughlin, John, Merletti, Franco, Mirabelli, Dario, Pándics, Tamás, Parent, Marie-Élise, Plato, Nils, Pohlabeln, Hermann, Richiardi, Lorenzo, Siemiatycki, Jack, Świątkowska, Beata, Tardón, Adonina, Wichmann, Heinz-Erich, Zaridze, David, Straif, Kurt, Kromhout, Hans, Vermeulen, Roel
Published in American journal of respiratory and critical care medicine (01.08.2020)
Published in American journal of respiratory and critical care medicine (01.08.2020)
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Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder
Lalovic, Bojan, Majid, Oneeb, Aluri, Jagadeesh, Landry, Ishani, Moline, Margaret, Hussein, Ziad
Published in Journal of clinical pharmacology (01.12.2020)
Published in Journal of clinical pharmacology (01.12.2020)
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A Time-to-Event Exposure-Response Model for Amyloid-Related Imaging Abnormalities Following Administration of Aducanumab to Subjects With Early Alzheimer Disease
Muralidharan, Kumar Kandadi, Karumanchi, Sravan, Kowalski, Kenneth G, Burkett, Patrick, Chapel, Sunny, Rajagovindan, Raj, Nestorov, Ivan
Published in Journal of clinical pharmacology (01.08.2022)
Published in Journal of clinical pharmacology (01.08.2022)
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Model‐Informed Dosing of Venetoclax in Healthy Subjects: An Exposure−Response Analysis
Dave, Nimita, Gopalakrishnan, Sathej, Mensing, Sven, Salem, Ahmed Hamed
Published in Clinical and translational science (01.11.2019)
Published in Clinical and translational science (01.11.2019)
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Safety, pharmacokinetics and exploratory exposure-response analysis of CX3002, a novel inhibitor of Xa, in Chinese healthy subjects
Chen, Wenjun, Ruan, Zourong, Lou, Honggang, Wang, Lu, Shao, Rong, Li, Fenghua, Jiang, Bo
Published in European journal of pharmaceutical sciences (01.06.2023)
Published in European journal of pharmaceutical sciences (01.06.2023)
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Ustekinumab Pharmacokinetics and Exposure Response in a Phase 3 Randomized Trial of Patients With Ulcerative Colitis
Adedokun, Omoniyi J., Xu, Zhenhua, Marano, Colleen, O’Brien, Chris, Szapary, Philippe, Zhang, Hongyan, Johanns, Jewel, Leong, Rupert W., Hisamatsu, Tadakazu, Van Assche, Gert, Danese, Silvio, Abreu, Maria T., Sands, Bruce E., Sandborn, William J.
Published in Clinical gastroenterology and hepatology (01.09.2020)
Published in Clinical gastroenterology and hepatology (01.09.2020)
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Population Pharmacokinetics, Efficacy Exposure-response Analysis, and Model-based Meta-analysis of Fenebrutinib in Subjects with Rheumatoid Arthritis
Chan, Phyllis, Yu, Jiajie, Chinn, Leslie, Prohn, Marita, Huisman, Jan, Matzuka, Brett, Hanley, William, Tuckwell, Katie, Quartino, Angelica
Published in Pharmaceutical research (01.02.2020)
Published in Pharmaceutical research (01.02.2020)
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Population pharmacokinetic and exposure–response analysis of apremilast in Japanese subjects with moderate to severe psoriasis
Okubo, Yukari, Ohtsuki, Mamitaro, Komine, Mayumi, Imafuku, Shinichi, Kassir, Nastya, Petric, Rosemary, Nemoto, Osamu
Published in Journal of dermatology (01.11.2021)
Published in Journal of dermatology (01.11.2021)
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Population Pharmacokinetic Modeling and Exposure‐Response Analysis for Aripiprazole Once Monthly in Subjects With Schizophrenia
Wang, Xiaofeng, Raoufinia, Arash, Bihorel, Sébastien, Passarell, Julie, Mallikaarjun, Suresh, Phillips, Luann
Published in Clinical pharmacology in drug development (01.02.2022)
Published in Clinical pharmacology in drug development (01.02.2022)
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