Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis
Exertier, Cécile, Salerno, Alessandra, Antonelli, Lorenzo, Fiorillo, Annarita, Ocello, Riccardo, Seghetti, Francesca, Caciolla, Jessica, Uliassi, Elisa, Masetti, Matteo, Fiorentino, Eleonora, Orsini, Stefania, Di Muccio, Trentina, Ilari, Andrea, Bolognesi, Maria Laura
Published in Journal of medicinal chemistry (11.01.2024)
Published in Journal of medicinal chemistry (11.01.2024)
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Journal Article
Charge transfer driven by ultrafast spin transition in a CoFe Prussian blue analogue
Cammarata, Marco, Zerdane, Serhane, Balducci, Lodovico, Azzolina, Giovanni, Mazerat, Sandra, Exertier, Cecile, Trabuco, Matilde, Levantino, Matteo, Alonso-Mori, Roberto, Glownia, James M., Song, Sanghoon, Catala, Laure, Mallah, Talal, Matar, Samir F., Collet, Eric
Published in Nature chemistry (01.01.2021)
Published in Nature chemistry (01.01.2021)
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Journal Article
Neuroglobin, clues to function and mechanism
Exertier, Cécile, Montemiglio, Linda Celeste, Freda, Ida, Gugole, Elena, Parisi, Giacomo, Savino, Carmelinda, Vallone, Beatrice
Published in Molecular aspects of medicine (01.04.2022)
Published in Molecular aspects of medicine (01.04.2022)
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Journal Article
Detecting rotational disorder in heme proteins: A comparison between resonance Raman spectroscopy, nuclear magnetic resonance, and circular dichroism
Sebastiani, Federico, Milazzo, Lisa, Exertier, Cécile, Becucci, Maurizio, Smulevich, Giulietta
Published in Journal of Raman spectroscopy (01.12.2021)
Published in Journal of Raman spectroscopy (01.12.2021)
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Journal Article
Lack of orientation selectivity of the heme insertion in murine neuroglobin revealed by resonance Raman spectroscopy
Milazzo, Lisa, Exertier, Cécile, Becucci, Maurizio, Freda, Ida, Montemiglio, Linda Celeste, Savino, Carmelinda, Vallone, Beatrice, Smulevich, Giulietta
Published in The FEBS journal (01.09.2020)
Published in The FEBS journal (01.09.2020)
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Journal Article
Probing the Role of Murine Neuroglobin CDloop–D-Helix Unit in CO Ligand Binding and Structural Dynamics
Exertier, Cécile, Sebastiani, Federico, Freda, Ida, Gugole, Elena, Cerutti, Gabriele, Parisi, Giacomo, Montemiglio, Linda Celeste, Becucci, Maurizio, Viappiani, Cristiano, Bruno, Stefano, Savino, Carmelinda, Zamparelli, Carlotta, Anselmi, Massimiliano, Abbruzzetti, Stefania, Smulevich, Giulietta, Vallone, Beatrice
Published in ACS chemical biology (19.08.2022)
Published in ACS chemical biology (19.08.2022)
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Journal Article
Inhibition of Leishmania infantum Trypanothione Reductase by New Aminopropanone Derivatives Interacting with the NADPH Binding Site
Madia, Valentina Noemi, Ialongo, Davide, Patacchini, Elisa, Exertier, Cécile, Antonelli, Lorenzo, Colotti, Gianni, Messore, Antonella, Tudino, Valeria, Saccoliti, Francesco, Scipione, Luigi, Ilari, Andrea, Costi, Roberta, Di Santo, Roberto
Published in Molecules (Basel, Switzerland) (01.01.2023)
Published in Molecules (Basel, Switzerland) (01.01.2023)
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Journal Article
Binding of steroid substrates reveals the key to the productive transition of the cytochrome P450 OleP
Costanzo, Antonella, Fata, Francesca, Freda, Ida, De Sciscio, Maria Laura, Gugole, Elena, Bulfaro, Giovanni, Di Renzo, Matteo, Barbizzi, Luca, Exertier, Cécile, Parisi, Giacomo, D’Abramo, Marco, Vallone, Beatrice, Savino, Carmelinda, Montemiglio, Linda Celeste
Published in Structure (London) (05.09.2024)
Published in Structure (London) (05.09.2024)
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Journal Article
Effect of Salts on the Conformational Dynamics of the Cytochrome P450 OleP
De Sciscio, Maria Laura, Nardi, Alessandro Nicola, Parisi, Giacomo, Bulfaro, Giovanni, Costanzo, Antonella, Gugole, Elena, Exertier, Cécile, Freda, Ida, Savino, Carmelinda, Vallone, Beatrice, Montemiglio, Linda Celeste, D'Abramo, Marco
Published in Molecules (Basel, Switzerland) (13.01.2023)
Published in Molecules (Basel, Switzerland) (13.01.2023)
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Journal Article
Sorcin in Cancer Development and Chemotherapeutic Drug Resistance
Exertier, Cécile, Antonelli, Lorenzo, Fiorillo, Annarita, Bernardini, Roberta, Colotti, Beatrice, Ilari, Andrea, Colotti, Gianni
Published in Cancers (09.08.2024)
Published in Cancers (09.08.2024)
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Journal Article
Substrate-induced conformational change in cytochrome P450 OleP
Parisi, Giacomo, Montemiglio, Linda Celeste, Giuffrè, Alessandro, Macone, Alberto, Scaglione, Antonella, Cerutti, Gabriele, Exertier, Cécile, Savino, Carmelinda, Vallone, Beatrice
Published in The FASEB journal (01.02.2019)
Published in The FASEB journal (01.02.2019)
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Journal Article
Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR
Freda, Ida, Exertier, Cécile, Barile, Anna, Chaves-Sanjuan, Antonio, Vega, Mirella Vivoli, Isupov, Michail N, Harmer, Nicholas J, Gugole, Elena, Swuec, Paolo, Bolognesi, Martino, Scipioni, Anita, Savino, Carmelinda, Di Salvo, Martino Luigi, Contestabile, Roberto, Vallone, Beatrice, Tramonti, Angela, Montemiglio, Linda Celeste
Published in Nucleic acids research (25.08.2023)
Published in Nucleic acids research (25.08.2023)
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Journal Article
The Nuts and Bolts of SARS-CoV-2 Spike Receptor-Binding Domain Heterologous Expression
Maffei, Mariano, Montemiglio, Linda Celeste, Vitagliano, Grazia, Fedele, Luigi, Sellathurai, Shaila, Bucci, Federica, Compagnone, Mirco, Chiarini, Valerio, Exertier, Cécile, Muzi, Alessia, Roscilli, Giuseppe, Vallone, Beatrice, Marra, Emanuele
Published in Biomolecules (Basel, Switzerland) (02.12.2021)
Published in Biomolecules (Basel, Switzerland) (02.12.2021)
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Journal Article
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach
Battista, Theo, Federico, Stefano, Brogi, Simone, Pozzetti, Luca, Khan, Tuhina, Butini, Stefania, Ramunno, Anna, Fiorentino, Eleonora, Orsini, Stefania, Di Muccio, Trentina, Fiorillo, Annarita, Exertier, Cécile, Di Risola, Daniel, Colotti, Gianni, Gemma, Sandra, Ilari, Andrea, Campiani, Giuseppe
Published in ACS infectious diseases (12.08.2022)
Published in ACS infectious diseases (12.08.2022)
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Journal Article
Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating
Exertier, Cécile, Milazzo, Lisa, Freda, Ida, Montemiglio, Linda Celeste, Scaglione, Antonella, Cerutti, Gabriele, Parisi, Giacomo, Anselmi, Massimiliano, Smulevich, Giulietta, Savino, Carmelinda, Vallone, Beatrice
Published in Scientific reports (29.03.2019)
Published in Scientific reports (29.03.2019)
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Journal Article
ALS2-Related Motor Neuron Diseases: From Symptoms to Molecules
Miceli, Marcello, Exertier, Cécile, Cavaglià, Marco, Gugole, Elena, Boccardo, Marta, Casaluci, Rossana Rita, Ceccarelli, Noemi, De Maio, Alessandra, Vallone, Beatrice, Deriu, Marco A
Published in Biology (Basel, Switzerland) (05.01.2022)
Published in Biology (Basel, Switzerland) (05.01.2022)
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Journal Article
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design
Fiorillo, Annarita, Colotti, Gianni, Exertier, Cécile, Liuzzi, Anastasia, Seghetti, Francesca, Salerno, Alessandra, Caciolla, Jessica, Ilari, Andrea
Published in Frontiers in molecular biosciences (04.07.2022)
Published in Frontiers in molecular biosciences (04.07.2022)
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Journal Article
Point Mutations at a Key Site Alter the Cytochrome P450 OleP Structural Dynamics
Montemiglio, Linda Celeste, Gugole, Elena, Freda, Ida, Exertier, Cécile, D'Auria, Lucia, Chen, Cheng Giuseppe, Nardi, Alessandro Nicola, Cerutti, Gabriele, Parisi, Giacomo, D'Abramo, Marco, Savino, Carmelinda, Vallone, Beatrice
Published in Biomolecules (Basel, Switzerland) (31.12.2021)
Published in Biomolecules (Basel, Switzerland) (31.12.2021)
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Journal Article
ESI MS Studies Of T. brucei Trypanothione Reductase And Its Reactions With Selected Metal Compounds
Zineddu, Stefano, Geri, Andrea, Ilari, Andrea, Colotti, Gianni, Exertier, Cécile, Fiorillo, Annarita, Antonelli, Lorenzo, Messori, Luigi
Published in European journal of inorganic chemistry (14.10.2024)
Published in European journal of inorganic chemistry (14.10.2024)
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Journal Article
Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate
Parisi, Giacomo, Freda, Ida, Exertier, Cécile, Cecchetti, Cristina, Gugole, Elena, Cerutti, Gabriele, D'Auria, Lucia, Macone, Alberto, Vallone, Beatrice, Savino, Carmelinda, Montemiglio, Linda Celeste
Published in Biomolecules (Basel, Switzerland) (06.10.2020)
Published in Biomolecules (Basel, Switzerland) (06.10.2020)
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