Marine-Derived Anticancer Agents: Clinical Benefits, Innovative Mechanisms, and New Targets
Pereira, Renato B, Evdokimov, Nikolai M, Lefranc, Florence, Valentão, Patrícia, Kornienko, Alexander, Pereira, David M, Andrade, Paula B, Gomes, Nelson G M
Published in Marine drugs (02.06.2019)
Published in Marine drugs (02.06.2019)
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Journal Article
A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation
Zhang, Xiao-Nan, Cheng, Qinqin, Chen, Jingwen, Lam, Albert T., Lu, Yanran, Dai, Zhefu, Pei, Hua, Evdokimov, Nikolai M., Louie, Stan G., Zhang, Yong
Published in Nature communications (13.09.2019)
Published in Nature communications (13.09.2019)
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Journal Article
One-Pot Multicomponent Synthesis of Diversely Substituted 2-Aminopyrroles. A Short General Synthesis of Rigidins A, B, C, and D
Frolova, Liliya V, Evdokimov, Nikolai M, Hayden, Kathryn, Malik, Indranil, Rogelj, Snezna, Kornienko, Alexander, Magedov, Igor V
Published in Organic letters (04.03.2011)
Published in Organic letters (04.03.2011)
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Journal Article
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver
Clark, Peter M, Flores, Graciela, Evdokimov, Nikolai M, McCracken, Melissa N, Chai, Timothy, Nair-Gill, Evan, O'Mahony, Fiona, Beaven, Simon W, Faull, Kym F, Phelps, Michael E, Jung, Michael E, Witte, Owen N
Published in Proceedings of the National Academy of Sciences - PNAS (15.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (15.07.2014)
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Journal Article
In search of a cytostatic agent derived from the alkaloid lycorine: Synthesis and growth inhibitory properties of lycorine derivatives
Evdokimov, Nikolai M., Lamoral-Theys, Delphine, Mathieu, Véronique, Andolfi, Anna, Frolova, Liliya V., Pelly, Stephen C., van Otterlo, Willem A.L., Magedov, Igor V., Kiss, Robert, Evidente, Antonio, Kornienko, Alexander
Published in Bioorganic & medicinal chemistry (01.12.2011)
Published in Bioorganic & medicinal chemistry (01.12.2011)
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Journal Article
Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines
Magedov, Igor V., Luchetti, Giovanni, Evdokimov, Nikolai M., Manpadi, Madhuri, Steelant, Wim F.A., Van slambrouck, Severine, Tongwa, Paul, Antipin, Mikhail Yu, Kornienko, Alexander
Published in Bioorganic & medicinal chemistry (15.02.2008)
Published in Bioorganic & medicinal chemistry (15.02.2008)
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Journal Article
Antiproliferative and apoptosis inducing properties of pyrano[3,2- c]pyridones accessible by a one-step multicomponent synthesis
Magedov, Igor V., Manpadi, Madhuri, Evdokimov, Nikolai M., Elias, Eerik M., Rozhkova, Elena, Ogasawara, Marcia A., Bettale, Jennifer D., Przheval’skii, Nikolai M., Rogelj, Snezna, Kornienko, Alexander
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Journal Article
Isatin derivatives with activity against apoptosis-resistant cancer cells
Evdokimov, Nikolai M., Magedov, Igor V., McBrayer, Dominic, Kornienko, Alexander
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
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Journal Article
One-Step Synthesis of Heterocyclic Privileged Medicinal Scaffolds by a Multicomponent Reaction of Malononitrile with Aldehydes and Thiols
Evdokimov, Nikolai M, Kireev, Artem S, Yakovenko, Andrey A, Antipin, Mikhail Yu, Magedov, Igor V, Kornienko, Alexander
Published in Journal of organic chemistry (27.04.2007)
Published in Journal of organic chemistry (27.04.2007)
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Journal Article
Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolones
Magedov, Igor V, Manpadi, Madhuri, Ogasawara, Marcia A, Dhawan, Adriana S, Rogelj, Snezna, Van slambrouck, Severine, Steelant, Wim F. A, Evdokimov, Nikolai M, Uglinskii, Pavel Y, Elias, Eerik M, Knee, Erica J, Tongwa, Paul, Antipin, Mikhail Yu, Kornienko, Alexander
Published in Journal of medicinal chemistry (24.04.2008)
Published in Journal of medicinal chemistry (24.04.2008)
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Journal Article
Development of 2‑Deoxy-2‑[18F]fluororibose for Positron Emission Tomography Imaging Liver Function in Vivo
Evdokimov, Nikolai M., Clark, Peter M., Flores, Graciela, Chai, Timothy, Faull, Kym F., Phelps, Michael E., Witte, Owen N., Jung, Michael E.
Published in Journal of medicinal chemistry (23.07.2015)
Published in Journal of medicinal chemistry (23.07.2015)
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Journal Article
Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 3. Fused Uracil-Containing Heterocycles as Novel Topoisomerase-Targeting Agents
Evdokimov, Nikolai M, Van slambrouck, Severine, Heffeter, Petra, Tu, Lee, Le Calvé, Benjamin, Lamoral-Theys, Delphine, Hooten, Carla J, Uglinskii, Pavel Y, Rogelj, Snezna, Kiss, Robert, Steelant, Wim F. A, Berger, Walter, Yang, Jeremy J, Bologa, Cristian G, Kornienko, Alexander, Magedov, Igor V
Published in Journal of medicinal chemistry (14.04.2011)
Published in Journal of medicinal chemistry (14.04.2011)
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Journal Article
Exploring Natural Product Chemistry and Biology with Multicomponent Reactions. 5. Discovery of a Novel Tubulin-Targeting Scaffold Derived from the Rigidin Family of Marine Alkaloids
Frolova, Liliya V, Magedov, Igor V, Romero, Anntherese E, Karki, Menuka, Otero, Isaiah, Hayden, Kathryn, Evdokimov, Nikolai M, Banuls, Laetitia Moreno Y, Rastogi, Shiva K, Smith, W. Ross, Lu, Shi-Long, Kiss, Robert, Shuster, Charles B, Hamel, Ernest, Betancourt, Tania, Rogelj, Snezna, Kornienko, Alexander
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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Journal Article
Aryliodine(III) diacetates as substrates for Pd–Ag catalyzed arylation of alkenes
Evdokimov, Nikolai M., Kornienko, Alexander, Magedov, Igor V.
Published in Tetrahedron letters (17.08.2011)
Published in Tetrahedron letters (17.08.2011)
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Journal Article
Anticancer Properties of an Important Drug Lead Podophyllotoxin Can Be Efficiently Mimicked by Diverse Heterocyclic Scaffolds Accessible via One-Step Synthesis
Magedov, Igor V, Frolova, Liliya, Manpadi, Madhuri, Bhoga, Uma devi, Tang, Hong, Evdokimov, Nikolai M, George, Olivia, Hadje Georgiou, Kathy, Renner, Steffen, Getlik, Matthäus, Kinnibrugh, Tiffany L, Fernandes, Manuel A, Van slambrouck, Severine, Steelant, Wim F. A, Shuster, Charles B, Rogelj, Snezna, van Otterlo, Willem A. L, Kornienko, Alexander
Published in Journal of medicinal chemistry (23.06.2011)
Published in Journal of medicinal chemistry (23.06.2011)
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Journal Article
Structural simplification of bioactive natural products with multicomponent synthesis. 4. 4H-Pyrano-[2,3-b]naphthoquinones with anticancer activity
Magedov, Igor V., Kireev, Artem S., Jenkins, Aaron R., Evdokimov, Nikolai M., Lima, Dustin T., Tongwa, Paul, Altig, Jeff, A. Steelant, Wim F., Van slambrouck, Severine, Antipin, Mikhail Yu, Kornienko, Alexander
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
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Journal Article
Lipophilic prodrug conjugates allow facile and rapid synthesis of high-loading capacity liposomes without the need for post-assembly purification
Mikhalin, Alexander A., Evdokimov, Nikolai M., Frolova, Liliya V., Magedov, Igor V., Kornienko, Alexander, Johnston, Robert, Rogelj, Snezna, Tartis, Michaelann S.
Published in Journal of liposome research (01.09.2015)
Published in Journal of liposome research (01.09.2015)
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Journal Article
Reengineered epipodophyllotoxin
Magedov, Igor V., Evdokimov, Nikolai M., Karki, Menuka, Peretti, Amanda S., Lima, Dustin T., Frolova, Liliya V., Reisenauer, Mary R., Romero, Anntherese E., Tongwa, Paul, Fonari, Alexandr, Altig, Jeff, Rogelj, Snezna, Antipin, Mikhail Yu, Shuster, Charles B., Kornienko, Alexander
Published in Chemical communications (Cambridge, England) (28.10.2012)
Published in Chemical communications (Cambridge, England) (28.10.2012)
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