Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model
Lood, Rolf, Winer, Benjamin Y, Pelzek, Adam J, Diez-Martinez, Roberto, Thandar, Mya, Euler, Chad W, Schuch, Raymond, Fischetti, Vincent A
Published in Antimicrobial agents and chemotherapy (01.04.2015)
Published in Antimicrobial agents and chemotherapy (01.04.2015)
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Novel Bacteriophage Lysin with Broad Lytic Activity Protects against Mixed Infection by Streptococcus pyogenes and Methicillin-Resistant Staphylococcus aureus
GILMER, Daniel B, SCHMITZ, Jonathan E, EULER, Chad W, FISCHETTI, Vincent A
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
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Journal Article
Using a Novel Lysin To Help Control Clostridium difficile Infections
Wang, Qiong, Euler, Chad W, Delaune, Aurelia, Fischetti, Vincent A
Published in Antimicrobial agents and chemotherapy (01.12.2015)
Published in Antimicrobial agents and chemotherapy (01.12.2015)
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Journal Article
PaP1, a Broad-Spectrum Lysin-Derived Cationic Peptide to Treat Polymicrobial Skin Infections
Heselpoth, Ryan D, Euler, Chad W, Fischetti, Vincent A
Published in Frontiers in microbiology (10.03.2022)
Published in Frontiers in microbiology (10.03.2022)
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Journal Article
The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa
Gilmer, Daniel B, Schmitz, Jonathan E, Thandar, Mya, Euler, Chad W, Fischetti, Vincent A
Published in PloS one (03.01.2017)
Published in PloS one (03.01.2017)
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Elimination of Chromosomal Island SpyCIM1 from Streptococcus pyogenes Strain SF370 Reverses the Mutator Phenotype and Alters Global Transcription
Hendrickson, Christina, Euler, Chad W, Nguyen, Scott V, Rahman, Maliha, McCullor, Kimberly A, King, Catherine J, Fischetti, Vincent A, McShan, W Michael
Published in PloS one (23.12.2015)
Published in PloS one (23.12.2015)
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Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials
Bikard, David, Euler, Chad W, Jiang, Wenyan, Nussenzweig, Philip M, Goldberg, Gregory W, Duportet, Xavier, Fischetti, Vincent A, Marraffini, Luciano A
Published in Nature biotechnology (01.11.2014)
Published in Nature biotechnology (01.11.2014)
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Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii
Thandar, Mya, Lood, Rolf, Winer, Benjamin Y, Deutsch, Douglas R, Euler, Chad W, Fischetti, Vincent A
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
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PlyKp104, a Novel Phage Lysin for the Treatment of Klebsiella pneumoniae, Pseudomonas aeruginosa, and Other Gram-Negative ESKAPE Pathogens
Euler, Chad W, Raz, Assaf, Hernandez, Anaise, Serrano, Anna, Xu, Siyue, Andersson, Martin, Zou, Geng, Zhang, Yue, Fischetti, Vincent A, Li, Jinquan
Published in Antimicrobial agents and chemotherapy (17.05.2023)
Published in Antimicrobial agents and chemotherapy (17.05.2023)
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A natural single-guide RNA repurposes Cas9 to autoregulate CRISPR-Cas expression
Workman, Rachael E., Pammi, Teja, Nguyen, Binh T.K., Graeff, Leonardo W., Smith, Erika, Sebald, Suzanne M., Stoltzfus, Marie J., Euler, Chad W., Modell, Joshua W.
Published in Cell (04.02.2021)
Published in Cell (04.02.2021)
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A Highly Active and Negatively Charged Streptococcus pyogenes Lysin with a Rare D-Alanyl-L-Alanine Endopeptidase Activity Protects Mice against Streptococcal Bacteremia
LOOD, Rolf, RAZ, Assaf, MOLINA, Henrik, EULER, Chad W, FISCHETTI, Vincent A
Published in Antimicrobial agents and chemotherapy (01.06.2014)
Published in Antimicrobial agents and chemotherapy (01.06.2014)
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A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae
Díez-Martínez, Roberto, De Paz, Héctor D, García-Fernández, Esther, Bustamante, Noemí, Euler, Chad W, Fischetti, Vincent A, Menendez, Margarita, García, Pedro
Published in Journal of antimicrobial chemotherapy (01.06.2015)
Published in Journal of antimicrobial chemotherapy (01.06.2015)
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