Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis
McKenzie, Brienne A., Mamik, Manmeet K., Saito, Leina B., Boghozian, Roobina, Monaco, Maria Chiara, Major, Eugene O., Lu, Jian-Qiang, Branton, William G., Power, Christopher
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2018)
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Journal Article
Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain
FERENCZY, Michael W, MARSHALL, Leslie J, NELSON, Christian D. S, ATWOOD, Walter J, NATH, Avindra, KHALILI, Kamel, MAJOR, Eugene O
Published in Clinical Microbiology Reviews (01.07.2012)
Published in Clinical Microbiology Reviews (01.07.2012)
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Journal Article
Natalizumab treatment for multiple sclerosis: updated recommendations for patient selection and monitoring
Kappos, Ludwig, Prof, Bates, David, Prof, Edan, Gilles, Prof, Eraksoy, Mefkûre, MD, Garcia-Merino, Antonio, MD, Grigoriadis, Nikolaos, MD, Hartung, Hans-Peter, Prof, Havrdová, Eva, MD, Hillert, Jan, MD, Hohlfeld, Reinhard, Prof, Kremenchutzky, Marcelo, MD, Lyon-Caen, Olivier, Prof, Miller, Ariel, MD, Pozzilli, Carlo, Prof, Ravnborg, Mads, MD, Saida, Takahiko, MD, Sindic, Christian, Prof, Vass, Karl, MD, Clifford, David B, Prof, Hauser, Stephen, Prof, Major, Eugene O, PhD, O'Connor, Paul W, Prof, Weiner, Howard L, Prof, Clanet, Michel, Prof, Gold, Ralf, Prof, Hirsch, Hans H, Prof, Radü, Ernst-Wilhelm, Prof, Sørensen, Per Soelberg, Prof, King, John, MD
Published in Lancet neurology (01.08.2011)
Published in Lancet neurology (01.08.2011)
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Journal Article
Rearranged JC Virus Noncoding Control Regions Found in Progressive Multifocal Leukoencephalopathy Patient Samples Increase Virus Early Gene Expression and Replication Rate
GOSERT, Rainer, KARDAS, Piotr, MAJOR, Eugene O, HIRSCH, Hans H
Published in Journal of Virology (01.10.2010)
Published in Journal of Virology (01.10.2010)
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Journal Article
Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a Review from the Research on Adverse Drug Events and Reports (RADAR) Project
Carson, Kenneth R, MD, Focosi, Daniele, MD, Major, Eugene O, PhD, Petrini, Mario, MD, Richey, Elizabeth A, BA, West, Dennis P, PhD, Bennett, Charles L, MD
Published in The lancet oncology (01.08.2009)
Published in The lancet oncology (01.08.2009)
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Journal Article
JC virus quasispecies analysis reveals a complex viral population underlying progressive multifocal leukoencephalopathy and supports viral dissemination via the hematogenous route
Van Loy, Tom, Thys, Kim, Ryschkewitsch, Caroline, Lagatie, Ole, Monaco, Maria C, Major, Eugene O, Tritsmans, Luc, Stuyver, Lieven J
Published in Journal of virology (15.01.2015)
Published in Journal of virology (15.01.2015)
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Journal Article
Progressive Multifocal Leukoencephalopathy in Primary Immune Deficiencies: Stat1 Gain of Function and Review of the Literature
Zerbe, Christa S., Marciano, Beatriz E., Katial, Rohit K., Santos, Carah B., Adamo, Nick, Hsu, Amy P., Hanks, Mary E., Darnell, Dirk N., Quezado, Martha M., Frein, Cathleen, Barnhart, Lisa A., Anderson, Victoria L., Uzel, Gulbu, Freeman, Alexandra F., Lisco, Andrea, Nath, Avindra, Major, Eugene O., Sampaio, Elizabeth P., Holland, Steven M.
Published in Clinical infectious diseases (15.04.2016)
Published in Clinical infectious diseases (15.04.2016)
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Journal Article
Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring
Kappos, Ludwig, Prof, Bates, David, MD, Hartung, Hans-Peter, MD, Havrdova, Eva, MD, Miller, David, MD, Polman, Chris H, MD, Ravnborg, Mads, MD, Hauser, Stephen L, MD, Rudick, Richard A, MD, Weiner, Howard L, MD, O'Connor, Paul W, MD, King, John, MD, Radue, Ernst Wilhelm, MD, Yousry, Tarek, MD, Major, Eugene O, PhD, Clifford, David B, MD
Published in Lancet neurology (01.05.2007)
Published in Lancet neurology (01.05.2007)
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Journal Article
Identification of circulating CD31 + CD45 + cell populations with the potential to differentiate into erythroid cells
Monaco, Maria Chiara G, Maric, Dragan, Salvucci, Ombretta, Passeri, Cristina Antonetti Lamorgese, Accorsi, Patrizia, Major, Eugene O, Berardi, Anna Concetta
Published in Stem cell research & therapy (13.04.2021)
Published in Stem cell research & therapy (13.04.2021)
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Journal Article
CMX001 (1-O-Hexadecyloxypropyl-Cidofovir) Inhibits Polyomavirus JC Replication in Human Brain Progenitor-Derived Astrocytes
GOSERT, Rainer, HANSSEN RINALDO, Christine, WERNLI, Marion, MAJOR, Eugene O, HIRSCH, Hans H
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
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Journal Article
Donor Origin of BK Virus in Renal Transplantation and Role of HLA C7 in Susceptibility to Sustained BK Viremia
Bohl, Daniel L., Storch, Gregory A., Ryschkewitsch, Caroline, Gaudreault‐Keener, Monique, Schnitzler, Mark A., Major, Eugene O., Brennan, Daniel C.
Published in American journal of transplantation (01.09.2005)
Published in American journal of transplantation (01.09.2005)
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Journal Article
Traffic of JC Virus from Sites of Initial Infection to the Brain: The Path to Progressive Multifocal Leukoencephalopathy
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Journal Article
Conference Proceeding
Long-term outcome of progressive multifocal leukoencephalopathy with recombinant interleukin-2 treatment and an associated increase in the number of HPyV-2-specific T-cells: a case report
Hoff, Fieke W., Rolwes, John, Hardeman, Paula A., Perkins, Molly, Major, Eugene O., Douek, Daniel, Collins, Robert H., Greenberg, Benjamin M.
Published in Therapeutic advances in hematology (01.01.2023)
Published in Therapeutic advances in hematology (01.01.2023)
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Journal Article
Germline Genetic Risk Variants for Progressive Multifocal Leukoencephalopathy
Eis, Peggy S, Bruno, Christopher D, Richmond, Todd A, Koralnik, Igor J, Hanson, Barbara A, Major, Eugene O, Chow, Christina R, Hendel-Chavez, Houria, Stankoff, Bruno, Gasnault, Jacques, Taoufik, Yassine, Hatchwell, Eli
Published in Frontiers in neurology (17.03.2020)
Published in Frontiers in neurology (17.03.2020)
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Journal Article
Changes in JC virus-specific T cell responses during natalizumab treatment and in natalizumab-associated progressive multifocal leukoencephalopathy
Perkins, Molly R, Ryschkewitsch, Caroline, Liebner, Julia C, Monaco, Maria Chiara G, Himelfarb, Danielle, Ireland, Sara, Roque, Annelys, Edward, Heather L, Jensen, Peter N, Remington, Gina, Abraham, Thomas, Abraham, Jaspreet, Greenberg, Benjamin, Kaufman, Charles, LaGanke, Chris, Monson, Nancy L, Xu, Xiaoning, Frohman, Elliot, Major, Eugene O, Douek, Daniel C
Published in PLoS pathogens (01.11.2012)
Published in PLoS pathogens (01.11.2012)
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