NVP‐QBE170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia
Coote, K J, Paisley, D, Czarnecki, S, Tweed, M, Watson, H, Young, A, Sugar, R, Vyas, M, Smith, N J, Baettig, U, Groot‐Kormelink, P J, Gosling, M, Lock, R, Ethell, B, Williams, G, Schumacher, A, Harris, J, Abraham, W M, Sabater, J, Poll, C T, Faller, T, Collingwood, S P, Danahay, H
Published in British journal of pharmacology (01.06.2015)
Published in British journal of pharmacology (01.06.2015)
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Use of Cloned and Expressed Human UDP-Glucuronosyltransferases for the Assessment of Human Drug Conjugation and Identification of Potential Drug Interactions
ETHELL, Brian T, BEAUMONT, Kevin, RANGE, David J, BURCHELL, Brian
Published in Drug metabolism and disposition (01.01.2001)
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Published in Drug metabolism and disposition (01.01.2001)
Journal Article
Determination of the glucuronide metabolites of the topoisomerase I inhibitors 7-Ethyl 10-hydroxycamptothecin (SN-38) and NU/ICRF 505 by high-performance liquid chromatography
Cummings, J, Ethell, B. T, Boyd, G, Burchell, B, Smyth, J. F, Jodrell, D. I
Published in Chromatographia (2002)
Published in Chromatographia (2002)
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A Universal Radiochemical High-Performance Liquid Chromatographic Assay for the Determination of UDP-Glucuronosyltransferase Activity
Ethell, Brian T., Anderson, Gail D., Beaumont, Kevin, Rance, David J., Burchell, Brian
Published in Analytical biochemistry (01.01.1998)
Published in Analytical biochemistry (01.01.1998)
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Journal Article
Synthesis and inhibitory effect of a trisubstrate transition state analogue for UDP glucuronosyltransferases
Timmers, C.M., Dekker, M., Buijsman, R.C., van der Marel, G.A., Ethell, B., Anderson, G., Burchell, B., Mulder, G.J., van Boom, J.H.
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
Published in Bioorganic & medicinal chemistry letters (17.06.1997)
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Journal Article
NVP ‐ QBE 170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia
Coote, K J, Paisley, D, Czarnecki, S, Tweed, M, Watson, H, Young, A, Sugar, R, Vyas, M, Smith, N J, Baettig, U, Groot‐Kormelink, P J, Gosling, M, Lock, R, Ethell, B, Williams, G, Schumacher, A, Harris, J, Abraham, W M, Sabater, J, Poll, C T, Faller, T, Collingwood, S P, Danahay, H
Published in British journal of pharmacology (01.06.2015)
Published in British journal of pharmacology (01.06.2015)
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Journal Article
Drug-mediated toxicity caused by genetic deficiency of UDP-glucuronosyltransferases
Burchell, Brian, Soars, Matt, Monaghan, Gemma, Cassidy, Andy, Smith, Debbie, Ethell, Brian
Published in Toxicology letters (15.03.2000)
Published in Toxicology letters (15.03.2000)
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Journal Article
Characterization of Catechol Glucuronidation in Rat Liver
ANTONIO, Laurence, GRILLASCA, Joel-Paul, TASKINEN, Jyrki, ELOVAARA, Eivor, BURCHELL, Brian, PIET, Marie-Helene, ETHELL, Brian, OUZZINE, Mohamed, FOURNEL-GIGLEUX, Sylvie, MAGDALOU, Jacques
Published in Drug metabolism and disposition (01.02.2002)
Published in Drug metabolism and disposition (01.02.2002)
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Journal Article
Histone 2A stimulates glucose-6-phosphatase activity by permeabilization of liver microsomes
Benedetti, Angelo, Fulceri, Rosella, Allan, Bernard B, Houston, Pamela, Sukhodub, Andrey L, Marcolongo, Paola, Ethell, Brian, Burchell, Brian, Burchell, Ann
Published in Biochemical journal (15.10.2002)
Published in Biochemical journal (15.10.2002)
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Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: Reversal of resistance by food additives
CUMMINGS, Jeffrey, ETHELL, Brian T, JARDINE, Lesley, BOYD, Gary, MACPHERSON, Janet S, BURCHELL, Brian, SMYTH, John F, JODRELL, Duncan I
Published in Cancer research (Chicago, Ill.) (01.12.2003)
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Published in Cancer research (Chicago, Ill.) (01.12.2003)
Journal Article
Glucuronidation of Dihydroartemisinin in Vivo and by Human Liver Microsomes and Expressed UDP-Glucuronosyltransferases
ILETT, Kenneth F, ETHELL, Brian T, PARK, B. Kevin, EDWARDS, Geoffrey, MAGGS, James L, DAVIS, Timothy M. E, BATTY, Kevin T, BURCHELL, Brian, TRAN QUANG BINH, LE THI ANH THU, NGUYEN CANH HUNG, PIRMOHAMED, Munir
Published in Drug metabolism and disposition (01.09.2002)
Published in Drug metabolism and disposition (01.09.2002)
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Journal Article
CONJUGATION OF CATECHOLS BY RECOMBINANT HUMAN SULFOTRANSFERASES, UDP-GLUCURONOSYLTRANSFERASES, AND SOLUBLE CATECHOL O-METHYLTRANSFERASE: STRUCTURE-CONJUGATION RELATIONSHIPS AND PREDICTIVE MODELS
TASKINEN, Jyrki, ETHELL, Brian T, PIHLAVISTO, Pia, HOOD, Alan M, BURCHELL, Brian, COUGHTRIE, Michael W. H
Published in Drug metabolism and disposition (01.09.2003)
Published in Drug metabolism and disposition (01.09.2003)
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Journal Article
Determination of the glucuronide metabolites of the topoisomerase I inhibitors 7-ethyl 10-hydroxycamptothecin (SN-38) and NU/ICRF 505 by high-performance liquid chromatography
CUMMINGS, J, ETHELL, B. T, BOYD, G, BURCHELL, B, SMYTH, J. F, JODRELL, D. I
Published in Chromatographia (Wiesbaden) (2002)
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Published in Chromatographia (Wiesbaden) (2002)
Conference Proceeding
Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation
Cummings, Jeffrey, Boyd, Gary, Ethell, Brian T., Macpherson, Janet S., Burchell, Brian, Smyth, John F., Jodrell, Duncan I.
Published in Biochemical pharmacology (15.02.2002)
Published in Biochemical pharmacology (15.02.2002)
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Journal Article
Drug-mediated toxicity caused by genetic deficiency of UDP-glucuronosyltransferases
BURCHELL, B, SOARS, M, MONAGHAN, G, CASSIDY, A, SMITH, D, ETHELL, B
Published in Toxicology letters (2000)
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Published in Toxicology letters (2000)
Conference Proceeding
Glucuronidation of SN-38 and NU/ICRF 505 in Human Colon Cancer and Adjacent Normal Colon
CUMMINGS, Jeffrey, ETHELL, Brian T, JARDINE, Lesley, BURCHELL, Brian
Published in Anticancer research (01.05.2006)
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Published in Anticancer research (01.05.2006)
Journal Article
Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamily
Soars, Matthew G, Fettes, Michelle, O’Sullivan, Audrey C, Riley, Robert J, Ethell, Brian T, Burchell, Brian
Published in Biochemical pharmacology (15.04.2003)
Published in Biochemical pharmacology (15.04.2003)
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Journal Article