Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α‑Synuclein Mouse Models of Parkinson’s Disease
Kilpeläinen, Tommi P., Pätsi, Henri T., Svarcbahs, Reinis, Julku, Ulrika H., Eteläinen, Tony S., Cui, Hengjing, Auno, Samuli, Sipari, Nina, Norrbacka, Susanna, Leino, Teppo O., Jäntti, Maria, Myöhänen, Timo T., Wallén, Erik A. A.
Published in Journal of medicinal chemistry (08.06.2023)
Published in Journal of medicinal chemistry (08.06.2023)
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Removal of proteinase K resistant αSyn species does not correlate with cell survival in a virus vector-based Parkinson's disease mouse model
Eteläinen, Tony S., Kilpeläinen, Tommi P., Ignatius, Adele, Auno, Samuli, De Lorenzo, Francesca, Uhari-Väänänen, Johanna K., Julku, Ulrika H., Myöhänen, Timo T.
Published in Neuropharmacology (01.11.2022)
Published in Neuropharmacology (01.11.2022)
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Repeated Ethanol Exposure Alters DNA Methylation Status and Dynorphin/Kappa-Opioid Receptor Expression in Nucleus Accumbens of Alcohol-Preferring AA Rats
Niinep, Kerly, Anier, Kaili, Eteläinen, Tony, Piepponen, Petteri, Kalda, Anti
Published in Frontiers in genetics (24.11.2021)
Published in Frontiers in genetics (24.11.2021)
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A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
Eteläinen, Tony S, Silva, M Catarina, Uhari-Väänänen, Johanna K, De Lorenzo, Francesca, Jäntti, Maria H, Cui, Hengjing, Chavero-Pieres, Marta, Kilpeläinen, Tommi, Mechtler, Christina, Svarcbahs, Reinis, Seppälä, Erin, Savinainen, Juha R, Puris, Elena, Fricker, Gert, Gynther, Mikko, Julku, Ulrika H, Huttunen, Henri J, Haggarty, Stephen J, Myöhänen, Timo T
Published in Science translational medicine (12.04.2023)
Published in Science translational medicine (12.04.2023)
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Tetrazole as a Replacement of the Electrophilic Group in Characteristic Prolyl Oligopeptidase Inhibitors
Kilpeläinen, Tommi P, Tyni, Jonna K, Lahtela-Kakkonen, Maija K, Eteläinen, Tony S, Myöhänen, Timo T, Wallén, Erik A. A
Published in ACS medicinal chemistry letters (12.12.2019)
Published in ACS medicinal chemistry letters (12.12.2019)
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The selective κ-opioid receptor antagonist JDTic attenuates the alcohol deprivation effect in rats
Uhari-Väänänen, Johanna, Eteläinen, Tony, Bäckström, Pia, Oinio, Ville, Carroll, F. Ivy, Raasmaja, Atso, Kiianmaa, Kalervo, Piepponen, Petteri
Published in European neuropsychopharmacology (01.12.2019)
Published in European neuropsychopharmacology (01.12.2019)
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Novel Small‐Molecular Ligands for Prolyl Oligopeptidase to Combat Tauopathies
Eteläinen, Tony, Pätsi, Henri, Uhari‐Väänänen, Johanna, Aikkila, Hannes, Cui, Hengjing, De Lorenzo, Francesca, Kilpeläinen, Tommi, Julku, Ulrika, Wallén, Erik A.A., Myöhänen, Timo T
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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PREP BINDING LIGANDS
LEINO, Teppo, MYÖHÄNEN, Timo, ETELÄINEN, Tony, SVARCBAHS, Reinis, WALLEN, Erik, JUMPPANEN, Mikael, KILPELÄINEN, Tommi, UHARI-VÄÄNÄNEN, Johanna, PÄTSI, Henri
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
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