Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis
Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den Toom, Myrthe, Slütter, Bram, Kuiper, Johan, Duchene, Johan, Aslani, Maria, Megens, Remco T.A., van ‘t Veer, Cornelis, Kooij, Gijs, Schrijver, Roy, Hoeksema, Marten A., Boon, Louis, Fay, Francois, Tang, Jun, Baxter, Samantha, Jongejan, Aldo, Moerland, Perry D., Vriend, Gert, Bleijlevens, Boris, Fisher, Edward A., Duivenvoorden, Raphael, Gerdes, Norbert, de Winther, Menno P.J., Nicolaes, Gerry A., Mulder, Willem J.M., Weber, Christian, Lutgens, Esther
Published in Journal of the American College of Cardiology (06.02.2018)
Published in Journal of the American College of Cardiology (06.02.2018)
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Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology
Ridger, Victoria C, Boulanger, Chantal M, Angelillo-Scherrer, Anne, Badimon, Lina, Blanc-Brude, Olivier, Bochaton-Piallat, Marie-Luce, Boilard, Eric, Buzas, Edit I, Caporali, Andreas, Dignat-George, Françoise, Evans, Paul C, Lacroix, Romaric, Lutgens, Esther, Ketelhuth, Daniel F J, Nieuwland, Rienk, Toti, Florence, Tunon, Jose, Weber, Christian, Hoefer, Imo E
Published in Thrombosis and haemostasis (2017)
Published in Thrombosis and haemostasis (2017)
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Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy
Beldman, Thijs J, Malinova, Tsveta S, Desclos, Emilie, Grootemaat, Anita E, Misiak, Aresh L. S, van der Velden, Saskia, van Roomen, Cindy P. A. A, Beckers, Linda, van Veen, Henk A, Krawczyk, Przemyslaw M, Hoebe, Ron A, Sluimer, Judith C, Neele, Annette E, de Winther, Menno P. J, van der Wel, Nicole N, Lutgens, Esther, Mulder, Willem J. M, Huveneers, Stephan, Kluza, Ewelina
Published in ACS nano (24.12.2019)
Published in ACS nano (24.12.2019)
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Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society
Roeters van Lennep, Jeanine E, Tokgözoğlu, Lale S, Badimon, Lina, Dumanski, Sandra M, Gulati, Martha, Hess, Connie N, Holven, Kirsten B, Kavousi, Maryam, Kayıkçıoğlu, Meral, Lutgens, Esther, Michos, Erin D, Prescott, Eva, Stock, Jane K, Tybjaerg-Hansen, Anne, Wermer, Marieke J H, Benn, Marianne
Published in European heart journal (14.10.2023)
Published in European heart journal (14.10.2023)
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Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure
Bosch, Lena, de Haan, Judith, Seijkens, Tom, van Tiel, Claudia, Brans, Maike, Pasterkamp, Gerard, Lutgens, Esther, de Jager, Saskia
Published in International journal of cardiology (15.03.2019)
Published in International journal of cardiology (15.03.2019)
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Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis
Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Wang, Zheng, Dahlman, James E, Malagon-Lopez, Jose, Gujja, Sharvari, Cilfone, Nicholas A, Kauffman, Kevin J, Sun, Lele, Sun, Hongye, Zhang, Xinbo, Aryal, Binod, Canfran-Duque, Alberto, Liu, Rebecca, Kusters, Pascal, Sehgal, Alfica, Jiao, Yang, Anderson, Daniel G, Gulcher, Jeffrey, Fernandez-Hernando, Carlos, Lutgens, Esther, Schwartz, Martin A, Pober, Jordan S, Chittenden, Thomas W, Tellides, George, Simons, Michael
Published in Nature metabolism (01.09.2019)
Published in Nature metabolism (01.09.2019)
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The role of inflammatory signaling pathways involving the CD40L-CD40-TRAF cascade in animal models of diabetes and hypertension as well as coronary artery disease patients
Strohm, Lea, Daub, Steffen, Oelze, Matthias, Kuntic, Marin, Ubbens, Henning, Klein, Veronique, Hoefer, Imo E., von Kriegsheim, Alex, Kleinert, Hartmut, Weber, Christian, Atzler, Dorothee, Wild, Philipp, Münzel, Thomas, Knosalla, Christoph, Lutgens, Esther, Daiber, Andreas
Published in Free radical biology & medicine (20.05.2023)
Published in Free radical biology & medicine (20.05.2023)
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Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes
Gerdes, Norbert, Seijkens, Tom, Lievens, Dirk, Kuijpers, Marijke J.E, Winkels, Holger, Projahn, Delia, Hartwig, Helene, Beckers, Linda, Megens, Remco T.A, Boon, Louis, Noelle, Randolph J, Soehnlein, Oliver, Heemskerk, Johan W.M, Weber, Christian, Lutgens, Esther
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2016)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2016)
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Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies
Döring, Yvonne, Noels, Heidi, van der Vorst, Emiel P.C, Neideck, Carlos, Egea, Virginia, Drechsler, Maik, Mandl, Manuela, Pawig, Lukas, Jansen, Yvonne, Schröder, Katrin, Bidzhekov, Kiril, Megens, Remco T.A, Theelen, Wendy, Klinkhammer, Barbara M, Boor, Peter, Schurgers, Leon, van Gorp, Rick, Ries, Christian, Kusters, Pascal J.H, van der Wal, Allard, Hackeng, Tilman M, Gäbel, Gabor, Brandes, Ralf P, Soehnlein, Oliver, Lutgens, Esther, Vestweber, Dietmar, Teupser, Daniel, Holdt, Lesca M, Rader, Daniel J, Saleheen, Danish, Weber, Christian
Published in Circulation (New York, N.Y.) (25.07.2017)
Published in Circulation (New York, N.Y.) (25.07.2017)
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Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases
Hoogeveen, Renate M, Nahrendorf, Matthias, Riksen, Niels P, Netea, Mihai G, de Winther, Menno P J, Lutgens, Esther, Nordestgaard, Børge G, Neidhart, Michel, Stroes, Erik S G, Catapano, Alberico L, Bekkering, Siroon
Published in European heart journal (07.10.2018)
Published in European heart journal (07.10.2018)
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Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis
Beldman, Thijs J, Senders, Max L, Alaarg, Amr, Pérez-Medina, Carlos, Tang, Jun, Zhao, Yiming, Fay, Francois, Deichmöller, Jacqueline, Born, Benjamin, Desclos, Emilie, van der Wel, Nicole N, Hoebe, Ron A, Kohen, Fortune, Kartvelishvily, Elena, Neeman, Michal, Reiner, Thomas, Calcagno, Claudia, Fayad, Zahi A, de Winther, Menno P. J, Lutgens, Esther, Mulder, Willem J. M, Kluza, Ewelina
Published in ACS nano (27.06.2017)
Published in ACS nano (27.06.2017)
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Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages’ transition into a pro-inflammatory state
Bosmans, Laura A, van Tiel, Claudia M, Aarts, Suzanne A B M, Willemsen, Lisa, Baardman, Jeroen, van Os, Bram W, Toom, Myrthe den, Beckers, Linda, Ahern, David J, Levels, Johannes H M, Jongejan, Aldo, Moerland, Perry D, Verberk, Sanne G S, den Bossche, Jan van, de Winther, Menno M P J, Weber, Christian, Atzler, Dorothee, Monaco, Claudia, Gerdes, Norbert, Shami, Annelie, Lutgens, Esther
Published in Cardiovascular research (22.05.2023)
Published in Cardiovascular research (22.05.2023)
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Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC Working Group on Myocardial Function and the ESC Working Group on Cellular Biology of the Heart
van der Velden, Jolanda, Asselbergs, Folkert W, Bakkers, Jeroen, Batkai, Sandor, Bertrand, Luc, Bezzina, Connie R, Bot, Ilze, Brundel, Bianca J J M, Carrier, Lucie, Chamuleau, Steven, Ciccarelli, Michele, Dawson, Dana, Davidson, Sean M, Dendorfer, Andreas, Duncker, Dirk J, Eschenhagen, Thomas, Fabritz, Larissa, Falcão-Pires, Ines, Ferdinandy, Péter, Giacca, Mauro, Girao, Henrique, Gollmann-Tepeköylü, Can, Gyongyosi, Mariann, Guzik, Tomasz J, Hamdani, Nazha, Heymans, Stephane, Hilfiker, Andres, Hilfiker-Kleiner, Denise, Hoekstra, Alfons G, Hulot, Jean-Sébastien, Kuster, Diederik W D, van Laake, Linda W, Lecour, Sandrine, Leiner, Tim, Linke, Wolfgang A, Lumens, Joost, Lutgens, Esther, Madonna, Rosalinda, Maegdefessel, Lars, Mayr, Manuel, van der Meer, Peter, Passier, Robert, Perbellini, Filippo, Perrino, Cinzia, Pesce, Maurizio, Priori, Silvia, Remme, Carol Ann, Rosenhahn, Bodo, Schotten, Ulrich, Schulz, Rainer, Sipido, Karin R, Sluijter, Joost P G, van Steenbeek, Frank, Steffens, Sabine, Terracciano, Cesare M, Tocchetti, Carlo Gabriele, Vlasman, Patricia, Yeung, Kak Khee, Zacchigna, Serena, Zwaagman, Dayenne, Thum, Thomas
Published in Cardiovascular research (09.12.2022)
Published in Cardiovascular research (09.12.2022)
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Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice
Gissler, Mark Colin, Scherrer, Philipp, Anto-Michel, Nathaly, Pennig, Jan, Hoppe, Natalie, Füner, Lisa, Härdtner, Carmen, Stachon, Peter, Li, Xiaowei, Mitre, Lucia Sol, Marchini, Timoteo, Madl, Josef, Wadle, Carolin, Hilgendorf, Ingo, von Zur Mühlen, Constantin, Bode, Christoph, Weber, Christian, Lutgens, Esther, Wolf, Dennis, Gerdes, Norbert, Zirlik, Andreas, Willecke, Florian
Published in Thrombosis and haemostasis (01.11.2021)
Published in Thrombosis and haemostasis (01.11.2021)
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