Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model
Kelner, Michael J., McMorris, Trevor C., Rojas, Rafael J., Estes, Leita A., Suthipinijtham, Pharnuk
Published in Cancer chemotherapy and pharmacology (01.12.2008)
Published in Cancer chemotherapy and pharmacology (01.12.2008)
Get full text
Journal Article
Synergy of Irofulven in combination with various anti-metabolites, enzyme inhibitors, and miscellaneous agents in MV522 lung carcinoma cells: marked interaction with gemcitabine and 5-fluorouracil
Kelner, Michael J., McMorris, Trevor C., Rojas, Rafael J., Estes, Leita A., Suthipinijtham, Pharnuk
Published in Investigational new drugs (01.10.2008)
Published in Investigational new drugs (01.10.2008)
Get full text
Journal Article
Structure−Activity Studies of Antitumor Agent Irofulven (Hydroxymethylacylfulvene) and Analogues
McMorris, Trevor C, Yu, Jian, Lira, Ricardo, Dawe, Robin, MacDonald, John R, Waters, Stephen J, Estes, Leita A, Kelner, Michael J
Published in Journal of organic chemistry (07.09.2001)
Published in Journal of organic chemistry (07.09.2001)
Get full text
Journal Article
Structure-activity relationships of illudins: analogs with improved therapeutic index
McMorris, Trevor C, Kelner, Michael J, Wang, Wen, Estes, Leita A, Montoya, Mark A, Taetle, Raymond
Published in Journal of organic chemistry (01.12.1992)
Published in Journal of organic chemistry (01.12.1992)
Get full text
Journal Article
Efficacy of MGI 114 (HMAF) against the MRP+ metastatic MV522 lung carcinoma xenograft
Kelner, M J, McMorris, T C, Estes, L A, Oval, M Y, Rojas, R J, Lynn, J R, Lanham, K A, Samson, K M
Published in Anti-cancer drugs (01.03.2000)
Published in Anti-cancer drugs (01.03.2000)
Get more information
Journal Article
Design and Synthesis of Antitumor Acylfulvenes
McMorris, Trevor C, Yu, Jian, Hu, Yi, Estes, Leita A, Kelner, Michael J
Published in Journal of organic chemistry (02.05.1997)
Published in Journal of organic chemistry (02.05.1997)
Get full text
Journal Article
An acetal derivative of illudin S with improved antitumor activity
McMorris, Trevor C, Yu, Jian, Gantzel, Peter K, Estes, Leita A, Kelner, Michael J
Published in Tetrahedron letters (10.03.1997)
Published in Tetrahedron letters (10.03.1997)
Get full text
Journal Article
Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress
Kelner, M J, Bagnell, R D, Montoya, M A, Estes, L A, Forsberg, L, Morgenstern, R
Published in The Journal of biological chemistry (28.04.2000)
Published in The Journal of biological chemistry (28.04.2000)
Get full text
Journal Article
Structural Organization of the Microsomal Glutathione S-Transferase Gene (MGST1) on Chromosome 12p13.1–13.2
Kelner, Michael J., Bagnell, Richard D., Montoya, Mark A., Estes, Leita A., Forsberg, Lena, Morgenstern, Ralf
Published in The Journal of biological chemistry (28.04.2000)
Published in The Journal of biological chemistry (28.04.2000)
Get full text
Journal Article
Reaction of antitumor hydroxymethylacylfulvene (HMAF) with thiols
McMorris, Trevor C., Yu, Jian, Estes, Leita A., Kelner, Michael J.
Published in Tetrahedron (27.10.1997)
Published in Tetrahedron (27.10.1997)
Get full text
Journal Article
Efficacy of Acylfulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells
Kelner, M J, McMorris, T C, Estes, L, Starr, R J, Rutherford, M, Montoya, M, Samson, K M, Taetle, R
Published in Cancer research (Chicago, Ill.) (01.11.1995)
Get full text
Published in Cancer research (Chicago, Ill.) (01.11.1995)
Journal Article
Transfection with human copper-zinc superoxide dismutase induces bidirectional alterations in other antioxidant enzymes, proteins, growth factor response, and paraquat resistance
Kelner, Michael J., Bagnell, Richard, Montoya, Mark, Estes, Leita, Uglik, Slavomir F., Cerutti, Peter
Published in Free radical biology & medicine (01.03.1995)
Published in Free radical biology & medicine (01.03.1995)
Get full text
Journal Article
Characterization of illudin S sensitivity in DNA repair-deficient chinese hamster cells: Unusually high sensitivity of ercc2 and ercc3 DNA helicase-deficient mutants in comparison to other chemotherapeutic agents
Kelner, Michael J., McMorris, Trevor C., Estes, Leita, Rutherford, Mary, Montoya, Mark, Goldstein, Jill, Samson, Kyra, Starr, Robin, Taetle, Raymond
Published in Biochemical pharmacology (19.07.1994)
Published in Biochemical pharmacology (19.07.1994)
Get full text
Journal Article