Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions
Chandrasekaran, Sandhya, Espeso-Gil, Sergio, Loh, Yong-Hwee Eddie, Javidfar, Behnam, Kassim, Bibi, Zhu, Yueyan, Zhang, Yuan, Dong, Yuhao, Bicks, Lucy K., Li, Haixin, Rajarajan, Prashanth, Peter, Cyril J., Sun, Daijing, Agullo-Pascual, Esperanza, Iskhakova, Marina, Estill, Molly, Lesch, Bluma J., Shen, Li, Jiang, Yan, Akbarian, Schahram
Published in Nature communications (13.12.2021)
Published in Nature communications (13.12.2021)
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Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk
Rajarajan, Prashanth, Borrman, Tyler, Liao, Will, Schrode, Nadine, Flaherty, Erin, Casiño, Charlize, Powell, Samuel, Yashaswini, Chittampalli, LaMarca, Elizabeth A, Kassim, Bibi, Javidfar, Behnam, Espeso-Gil, Sergio, Li, Aiqun, Won, Hyejung, Geschwind, Daniel H, Ho, Seok-Man, MacDonald, Matthew, Hoffman, Gabriel E, Roussos, Panos, Zhang, Bin, Hahn, Chang-Gyu, Weng, Zhiping, Brennand, Kristen J, Akbarian, Schahram
Published in Science (American Association for the Advancement of Science) (14.12.2018)
Published in Science (American Association for the Advancement of Science) (14.12.2018)
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Spatial genome exploration in the context of cognitive and neurological disease
Rajarajan, Prashanth, Borrman, Tyler, Liao, Will, Espeso-Gil, Sergio, Chandrasekaran, Sandhya, Jiang, Yan, Weng, Zhiping, Brennand, Kristen J, Akbarian, Schahram
Published in Current opinion in neurobiology (01.12.2019)
Published in Current opinion in neurobiology (01.12.2019)
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Tangentially Migrating Neurons Assemble a Primary Cilium that Promotes Their Reorientation to the Cortical Plate
Baudoin, Jean-Pierre, Viou, Lucie, Launay, Pierre-Serge, Luccardini, Camilla, Espeso Gil, Sergio, Kiyasova, Vera, Irinopoulou, Théano, Alvarez, Chantal, Rio, Jean-Paul, Boudier, Thomas, Lechaire, Jean-Pierre, Kessaris, Nicoletta, Spassky, Nathalie, Métin, Christine
Published in Neuron (Cambridge, Mass.) (20.12.2012)
Published in Neuron (Cambridge, Mass.) (20.12.2012)
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In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene
Peter, Cyril J., Saito, Atsushi, Hasegawa, Yuto, Tanaka, Yuya, Nagpal, Mohika, Perez, Gabriel, Alway, Emily, Espeso-Gil, Sergio, Fayyad, Tariq, Ratner, Chana, Dincer, Aslihan, Gupta, Achla, Devi, Lakshmi, Pappas, John G., Lalonde, François M., Butman, John A., Han, Joan C., Akbarian, Schahram, Kamiya, Atsushi
Published in Nature communications (11.09.2019)
Published in Nature communications (11.09.2019)
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Functional annotation of rare structural variation in the human brain
Han, Lide, Zhao, Xuefang, Benton, Mary Lauren, Perumal, Thaneer, Collins, Ryan L., Hoffman, Gabriel E., Johnson, Jessica S., Sloofman, Laura, Wang, Harold Z., Stone, Matthew R., Brennand, Kristen J., Brand, Harrison, Sieberts, Solveig K., Marenco, Stefano, Peters, Mette A., Lipska, Barbara K., Roussos, Panos, Capra, John A., Talkowski, Michael, Ruderfer, Douglas M.
Published in Nature communications (12.06.2020)
Published in Nature communications (12.06.2020)
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Machine learning combining multi-omics data and network algorithms identifies adrenocortical carcinoma prognostic biomarkers
Martin-Hernandez, Roberto, Espeso-Gil, Sergio, Domingo, Clara, Latorre, Pablo, Hervas, Sergi, Hernandez Mora, Jose Ramon, Kotelnikova, Ekaterina
Published in Frontiers in molecular biosciences (06.11.2023)
Published in Frontiers in molecular biosciences (06.11.2023)
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Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition
Espeso-Gil, Sergio, Holik, Aliaksei Z, Bonnin, Sarah, Jhanwar, Shalu, Chandrasekaran, Sandhya, Pique-Regi, Roger, Albaigès-Ràfols, Júlia, Maher, Michael, Permanyer, Jon, Irimia, Manuel, Friedländer, Marc R, Pons-Espinal, Meritxell, Akbarian, Schahram, Dierssen, Mara, Maass, Philipp G, Hor, Charlotte N, Ossowski, Stephan
Published in Frontiers in molecular neuroscience (05.05.2021)
Published in Frontiers in molecular neuroscience (05.05.2021)
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A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons
Espeso-Gil, Sergio, Halene, Tobias, Bendl, Jaroslav, Kassim, Bibi, Ben Hutta, Gabriella, Iskhakova, Marina, Shokrian, Neda, Auluck, Pavan, Javidfar, Behnam, Rajarajan, Prashanth, Chandrasekaran, Sandhya, Peter, Cyril J, Cote, Alanna, Birnbaum, Rebecca, Liao, Will, Borrman, Tyler, Wiseman, Jennifer, Bell, Aaron, Bannon, Michael J, Roussos, Panagiotis, Crary, John F, Weng, Zhiping, Marenco, Stefano, Lipska, Barbara, Tsankova, Nadejda M, Huckins, Laura, Jiang, Yan, Akbarian, Schahram
Published in Genome medicine (19.02.2020)
Published in Genome medicine (19.02.2020)
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FGF signaling enhances a sonic hedgehog negative feedback loop at the initiation of spinal cord ventral patterning
Morales, Aixa V., Espeso‐Gil, Sergio, Ocaña, Inmaculada, Nieto‐Lopez, Francisco, Calleja, Elena, Bovolenta, Paola, Lewandoski, Mark, Diez del Corral, Ruth
Published in Developmental neurobiology (Hoboken, N.J.) (01.09.2016)
Published in Developmental neurobiology (Hoboken, N.J.) (01.09.2016)
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Spatial genome organization and cognition
Rajarajan, Prashanth, Gil, Sergio Espeso, Brennand, Kristen J., Akbarian, Schahram
Published in Nature reviews. Neuroscience (01.11.2016)
Published in Nature reviews. Neuroscience (01.11.2016)
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SATB2 organizes the 3D genome architecture of cognition in cortical neurons
Wahl, Nico, Espeso-Gil, Sergio, Chietera, Paola, Nagel, Amelie, Laighneach, Aodán, Morris, Derek W., Rajarajan, Prashanth, Akbarian, Schahram, Dechant, Georg, Apostolova, Galina
Published in Molecular cell (15.02.2024)
Published in Molecular cell (15.02.2024)
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Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia
Breen, Michael S., Dobbyn, Amanda, Li, Qin, Roussos, Panos, Hoffman, Gabriel E., Stahl, Eli, Chess, Andrew, Sklar, Pamela, Li, Jin Billy, Devlin, Bernie, Buxbaum, Joseph D.
Published in Nature neuroscience (01.09.2019)
Published in Nature neuroscience (01.09.2019)
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Neuronal Nsun2 Deficiency is Associated With Codon-Specific Epitranscriptomic Dysregulation of Gly-Trnas and Corresponding Proteomic Shift Impacting Synaptic Signaling and Behavior
Blaze, Jennifer, Phillips, Hannah, Heissel, Soeren, Navickas, Albertas, Plaza-Jennings, Amara, Foo, Marcus, Katanski, Christopher, Watkins, Christopher, Pennington, Zachary, Javidfar, Behnam, Espeso-Gil, Sergio, Molina, Henrik, Cai, Denise, Pan, Tao, Yao, Wei-Dong, Goodarzi, Hani, Haghighi, Fatemeh, Akbarian, Schahram
Published in Biological psychiatry (1969) (01.05.2021)
Published in Biological psychiatry (1969) (01.05.2021)
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Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
Sieberts, Solveig K., Perumal, Thanneer M., Carrasquillo, Minerva M., Allen, Mariet, Reddy, Joseph S., Hoffman, Gabriel E., Dang, Kristen K., Calley, John, Ebert, Philip J., Eddy, James, Wang, Xue, Greenwood, Anna K., Mostafavi, Sara, Omberg, Larsson, Peters, Mette A., Logsdon, Benjamin A., De Jager, Philip L., Ertekin-Taner, Nilüfer, Mangravite, Lara M.
Published in Scientific data (12.10.2020)
Published in Scientific data (12.10.2020)
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R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription
LaMarca, Elizabeth A, Saito, Atsushi, Plaza-Jennings, Amara, Espeso-Gil, Sergio, Hellmich, Allyse, Fernando, Michael B, Javidfar, Behnam, Liao, Will, Estill, Molly, Townsley, Kayla, Florio, Anna, Ethridge, James E, Do, Catherine, Tycko, Benjamin, Shen, Li, Kamiya, Atsushi, Tsankova, Nadejda M, Brennand, Kristen J, Akbarian, Schahram
Published in bioRxiv (18.07.2023)
Published in bioRxiv (18.07.2023)
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Journal Article
NEURON-SPECIFIC CHROMOSOMAL MEGADOMAIN ORGANIZATION IS ADAPTIVE TO RECENT RETROTRANSPOSON EXPANSIONS
Chandrasekaran, Sandhya, Espeso-Gil, Sergio, Yong-Hwee, Eddie Loh, Javidfar, Behnam, Kassim, Bibi, Dong, Yuhao, Zhu, Yueyan, Bicks, Lucy K, Rajarajan, Prashanth, Peter, Cyril J, Agullo-Pascual, Esperanza, Iskhakova, Marina, Estill, Molly, Shen, Li, Jiang, Yan, Akbarian, Schahram
Published in bioRxiv (01.09.2021)
Published in bioRxiv (01.09.2021)
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Paper
Environmental enrichment induces epigenomic and genome organization changes relevant for cognitive function
Espeso-Gil, Sergio, Holik, Aliaksei, Bonnin, Sarah, Jhanwar, Shalu, Chandrasekaran, Sandhya, Pique-Regi, Roger, Albaigès-Ràfols, Júlia, Maher, Michael, Permanyer, Jon, Irimia, Manuel, Friedländer, Marc R, Pons-Espinal, Meritxel, Akbarian, Schahram, Dierssen, Mara, Maass, Philipp G, Hor, Charlotte N, Ossowski, Stephan
Published in bioRxiv (02.02.2021)
Published in bioRxiv (02.02.2021)
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