Therapeutic Options for Mucopolysaccharidoses: Current and Emerging Treatments
Sawamoto, Kazuki, Stapleton, Molly, Alméciga-Díaz, Carlos J., Espejo-Mojica, Angela J., Losada, Juan Camilo, Suarez, Diego A., Tomatsu, Shunji
Published in Drugs (New York, N.Y.) (01.07.2019)
Published in Drugs (New York, N.Y.) (01.07.2019)
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Journal Article
Human recombinant lysosomal β‐Hexosaminidases produced in Pichia pastoris efficiently reduced lipid accumulation in Tay‐Sachs fibroblasts
Espejo‐Mojica, Angela J., Rodríguez‐López, Alexander, Li, Rong, Zheng, Wei, Alméciga‐Díaz, Carlos J., Dulcey‐Sepúlveda, Cindy, Combariza, Germán, Barrera, Luis A.
Published in American journal of medical genetics. Part C, Seminars in medical genetics (01.12.2020)
Published in American journal of medical genetics. Part C, Seminars in medical genetics (01.12.2020)
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Journal Article
Identification of Orthosteric and Allosteric Pharmacological Chaperones for Mucopolysaccharidosis Type IIIB
Losada, Juan Camilo, Triana, Heidy, Vanegas, Egdda, Caro, Angela, Rodríguez‐López, Alexander, Espejo‐Mojica, Angela Johana, Alméciga‐Diaz, Carlos Javier
Published in Chembiochem : a European journal of chemical biology (01.08.2024)
Published in Chembiochem : a European journal of chemical biology (01.08.2024)
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Journal Article
CRISPR/nCas9-Based Genome Editing on GM2 Gangliosidoses Fibroblasts via Non-Viral Vectors
Leal, Andrés Felipe, Cifuentes, Javier, Quezada, Valentina, Benincore-Flórez, Eliana, Cruz, Juan Carlos, Reyes, Luis Humberto, Espejo-Mojica, Angela Johana, Alméciga-Díaz, Carlos Javier
Published in International journal of molecular sciences (14.09.2022)
Published in International journal of molecular sciences (14.09.2022)
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Journal Article
Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome
Tomatsu, Shunji, Sawamoto, Kazuki, Alméciga-Díaz, Carlos J, Shimada, Tsutomu, Bober, Michael B, Chinen, Yasutsugu, Yabe, Hiromasa, Montaño, Adriana M, Giugliani, Roberto, Kubaski, Francyne, Yasuda, Eriko, Rodríguez-López, Alexander, Espejo-Mojica, Angela J, Sánchez, Oscar F, Mason, Robert W, Barrera, Luis A, Mackenzie, William G, Orii, Tadao
Published in Drug design, development and therapy (01.01.2015)
Published in Drug design, development and therapy (01.01.2015)
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Journal Article
Novel human recombinant N-acetylgalactosamine-6-sulfate sulfatase produced in a glyco-engineered Escherichia coli strain
Pimentel-Vera, Luisa N., Rodríguez-López, Alexander, Espejo-Mojica, Angela J., Ramírez, Aura María, Cardona, Carolina, Reyes, Luis H., Tomatsu, Shunji, Jaroentomeechai, Thapakorn, DeLisa, Matthew P., Sánchez, Oscar F., Alméciga-Díaz, Carlos J.
Published in Heliyon (30.06.2024)
Published in Heliyon (30.06.2024)
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Journal Article
A perspective on research, diagnosis, and management of lysosomal storage disorders in Colombia
Puentes-Tellez, María Alejandra, Lerma-Barbosa, Paula Andrea, Garzón-Jaramillo, Rafael Guillermo, Suarez, Diego A., Espejo-Mojica, Angela J., Guevara, Johana M., Echeverri, Olga Yaneth, Solano-Galarza, Daniela, Uribe-Ardila, Alfredo, Alméciga-Díaz, Carlos J.
Published in Heliyon (01.03.2020)
Published in Heliyon (01.03.2020)
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Journal Article
Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease
Vu, Mylinh, Li, Rong, Baskfield, Amanda, Lu, Billy, Farkhondeh, Atena, Gorshkov, Kirill, Motabar, Omid, Beers, Jeanette, Chen, Guokai, Zou, Jizhong, Espejo-Mojica, Angela J, Rodríguez-López, Alexander, Alméciga-Díaz, Carlos J, Barrera, Luis A, Jiang, Xuntian, Ory, Daniel S, Marugan, Juan J, Zheng, Wei
Published in Orphanet journal of rare diseases (17.09.2018)
Published in Orphanet journal of rare diseases (17.09.2018)
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Journal Article
Characterization of Human Recombinant N-Acetylgalactosamine-6-Sulfate Sulfatase Produced in Pichia pastoris as Potential Enzyme for Mucopolysaccharidosis IVA Treatment
Rodríguez-López, Alexander, Pimentel-Vera, Luisa N., Espejo-Mojica, Angela J., Van Hecke, Annelies, Tiels, Petra, Tomatsu, Shunji, Callewaert, Nico, Alméciga-Díaz, Carlos J.
Published in Journal of pharmaceutical sciences (01.08.2019)
Published in Journal of pharmaceutical sciences (01.08.2019)
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Journal Article
GM2 Gangliosidoses: Clinical Features, Pathophysiological Aspects, and Current Therapies
Leal, Andrés Felipe, Benincore-Flórez, Eliana, Solano-Galarza, Daniela, Garzón Jaramillo, Rafael Guillermo, Echeverri-Peña, Olga Yaneth, Suarez, Diego A, Alméciga-Díaz, Carlos Javier, Espejo-Mojica, Angela Johana
Published in International journal of molecular sciences (27.08.2020)
Published in International journal of molecular sciences (27.08.2020)
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Journal Article
Effect of two preservation methods on the viability and enzyme production of a recombinant Komagataella phaffii (Pichia pastoris) strain
Alvarado-Fernández, Angela María, Rodríguez-López, Edwin Alexander, Espejo-Mojica, Angela Johana, Mosquera-Arévalo, Angela Rocío, Alméciga-Díaz, Carlos Javier, Trespalacios-Rangel, Alba Alicia
Published in Cryobiology (01.04.2022)
Published in Cryobiology (01.04.2022)
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Journal Article
Research, diagnosis and education in inborn errors of metabolism in Colombia: 20 years' experience from a reference center
Echeverri, Olga Y, Guevara, Johana M, Espejo-Mojica, Ángela J, Ardila, Andrea, Pulido, Ninna, Reyes, Magda, Rodriguez-Lopez, Alexander, Alméciga-Díaz, Carlos J, Barrera, Luis A
Published in Orphanet journal of rare diseases (16.08.2018)
Published in Orphanet journal of rare diseases (16.08.2018)
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Journal Article
Characterization of recombinant human lysosomal beta-hexosaminidases produced in the methylotrophic yeast Pichia pastoris
Espejo Mojica, Angela Johana, Mosquera, Angela Rocío, Rodríguez-López, Edwin Alexander, Díaz, Dennis Johana, Betrán, Laura Milena, Hernández, Francy Liliana, Alméciga Díaz, Carlos Javier, Barrera, Luis Alejandro
Published in Universitas scientiarum (2016)
Published in Universitas scientiarum (2016)
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Journal Article
Recombinant human N-acetylgalactosamine-6-sulfate sulfatase (GALNS) produced in the methylotrophic yeast Pichia pastoris
Rodríguez-López, Alexander, Alméciga-Díaz, Carlos J, Sánchez, Jhonnathan, Moreno, Jefferson, Beltran, Laura, Díaz, Dennis, Pardo, Andrea, Ramírez, Aura María, Espejo-Mojica, Angela J, Pimentel, Luisa, Barrera, Luis A
Published in Scientific reports (05.07.2016)
Published in Scientific reports (05.07.2016)
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Journal Article
Anaerobic sulfatase maturase AslB from Escherichia coli activates human recombinant iduronate-2-sulfate sulfatase (IDS) and N-acetylgalactosamine-6-sulfate sulfatase (GALNS)
Alméciga-Díaz, Carlos Javier, Tolosa-Díaz, Andrés Dario, Pimentel, Luisa Natalia, Bonilla, Yahir Andres, Rodríguez-López, Alexander, Espejo-Mojica, Angela J., Patiño, Juan D., Sánchez, Oscar F., Gonzalez-Santos, Janneth
Published in Gene (15.11.2017)
Published in Gene (15.11.2017)
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Journal Article
Production and characterization of a human lysosomal recombinant iduronate-2-sulfatase produced in Pichia pastoris
Pimentel, Natalia, Rodríguez-Lopez, Alexander, Díaz, Sergio, Losada, Juan C, Díaz-Rincón, Dennis J, Cardona, Carolina, Espejo-Mojica, Ángela J, Ramírez, Aura M, Ruiz, Fredy, Landázuri, Patricia, Poutou-Piñales, Raúl A, Cordoba-Ruiz, Henry A, Alméciga-D Íaz, Carlos J, Barrera-Avellaneda, Luis A
Published in Biotechnology and applied biochemistry (01.09.2018)
Published in Biotechnology and applied biochemistry (01.09.2018)
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Delivery and assessment of a CRISPR/nCas9-based genome editing system on in vitro models of mucopolysaccharidoses IVA assisted by magnetite-based nanoparticles
Leal, Andrés Felipe, Cifuentes, Javier, Torres, Carlos Emilio, Suárez, Diego, Quezada, Valentina, Gómez, Saúl Camilo, Cruz, Juan C, Reyes, Luis H, Espejo-Mojica, Angela Johana, Alméciga-Díaz, Carlos Javier
Published in Scientific reports (03.09.2022)
Published in Scientific reports (03.09.2022)
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Journal Article
Human recombinant lysosomal enzymes produced in microorganisms
Espejo-Mojica, Ángela J., Alméciga-Díaz, Carlos J., Rodríguez, Alexander, Mosquera, Ángela, Díaz, Dennis, Beltrán, Laura, Díaz, Sergio, Pimentel, Natalia, Moreno, Jefferson, Sánchez, Jhonnathan, Sánchez, Oscar F., Córdoba, Henry, Poutou-Piñales, Raúl A., Barrera, Luis A.
Published in Molecular genetics and metabolism (01.09.2015)
Published in Molecular genetics and metabolism (01.09.2015)
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Journal Article
Characterization and expression of domains of Alphaherpesvirus bovine 1/5 envelope glycoproteins B in Komagataella phaffi
Quintero Barbosa, Juan Sebastián, Rojas, Heidy Yohana Triana, Gonzalez, Janneth, Espejo-Mojica, Angela Johana, Díaz, Carlos Javier Alméciga, Gutierrez, María Fernanda
Published in BMC veterinary research (31.01.2023)
Published in BMC veterinary research (31.01.2023)
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Journal Article
Production of Recombinant Trichoderma reesei Cellobiohydrolase II in a New Expression System Based on Wickerhamomyces anomalus
Díaz-Rincón, Dennis J, Duque, Ivonne, Osorio, Erika, Rodríguez-López, Alexander, Espejo-Mojica, Angela, Parra-Giraldo, Claudia M, Poutou-Piñales, Raúl A, Alméciga-Díaz, Carlos J, Quevedo-Hidalgo, Balkys
Published in Enzyme Research (2017)
Published in Enzyme Research (2017)
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