Extracellular histones are major mediators of death in sepsis
Esmon, Charles T, Xu, Jun, Zhang, Xiaomei, Pelayo, Rosana, Monestier, Marc, Ammollo, Concetta T, Semeraro, Fabrizio, Taylor, Fletcher B, Esmon, Naomi L, Lupu, Florea
Published in Nature medicine (01.11.2009)
Published in Nature medicine (01.11.2009)
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Journal Article
Extracellular histones are mediators of death through TLR2 and TLR4 in mouse fatal liver injury
Xu, Jun, Zhang, Xiaomei, Monestier, Marc, Esmon, Naomi L, Esmon, Charles T
Published in The Journal of immunology (1950) (01.09.2011)
Published in The Journal of immunology (1950) (01.09.2011)
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Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4
Semeraro, Fabrizio, Ammollo, Concetta T., Morrissey, James H., Dale, George L., Friese, Paul, Esmon, Naomi L., Esmon, Charles T.
Published in Blood (18.08.2011)
Published in Blood (18.08.2011)
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Journal Article
Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome
Delvaeye, Mieke, Noris, Marina, De Vriese, Astrid, Esmon, Charles T, Esmon, Naomi L, Ferrell, Gary, Del-Favero, Jurgen, Plaisance, Stephane, Claes, Bart, Lambrechts, Diether, Zoja, Carla, Remuzzi, Giuseppe, Conway, Edward M
Published in The New England journal of medicine (23.07.2009)
Published in The New England journal of medicine (23.07.2009)
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Safety and efficacy of an anti–human APC antibody for prophylaxis of congenital factor deficiencies in preclinical models
Jiang, Miao, Yang, Fei, Jiang, Yizhi, Cheng, Lu, Han, Jingjing, Yi, Jiawei, Zuo, Bin, Huang, Lulu, Ma, Zhenni, Li, Tianyi, Cao, Lijuan J., Xia, Zhisong, Bai, Xia, Jia, Chenjun, Yang, Teddy Tat Chi, Esmon, Naomi L., Ruan, Changgeng, Xia, Lijun, Esmon, Charles T., Han, Yue, Wu, Depei, Xu, Jun
Published in Blood (21.09.2023)
Published in Blood (21.09.2023)
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Inhibition of endogenous activated protein C attenuates experimental autoimmune encephalomyelitis by inducing myeloid-derived suppressor cells
Alabanza, Leah M, Esmon, Naomi L, Esmon, Charles T, Bynoe, Margaret S
Published in The Journal of immunology (1950) (01.10.2013)
Published in The Journal of immunology (1950) (01.10.2013)
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Journal Article
Comparison of Methods to Determine Rivaroxaban anti-factor Xa activity
Rathbun, Suman, Tafur, Alfonso, Grant, Russell, Esmon, Naomi, Mauer, Karin, Marlar, Richard A
Published in Thrombosis research (01.02.2015)
Published in Thrombosis research (01.02.2015)
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The Endothelial Protein C Receptor Supports Tissue Factor Ternary Coagulation Initiation Complex Signaling through Protease-activated Receptors
Disse, Jennifer, Petersen, Helle Heibroch, Larsen, Katrine S., Persson, Egon, Esmon, Naomi, Esmon, Charles T., Teyton, Luc, Petersen, Lars C., Ruf, Wolfram
Published in The Journal of biological chemistry (18.02.2011)
Published in The Journal of biological chemistry (18.02.2011)
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Blocking human protein C anticoagulant activity improves clotting defects of hemophilia mice expressing human protein C
Jiang, Miao, Yang, Fei, Jiang, Yizhi, Cheng, Lu, Han, Jingjing, Yi, Jiawei, Zhang, Guige, Ma, Zhenni, Cao, Lijuan, Zuo, Bin, Zhou, Lixia, Huang, Lulu, Niu, Siying, Xia, Zhisong, Zhou, Xuefeng, Bai, Xia, Esmon, Naomi L., Ruan, Changgeng, Xia, Lijun, Han, Yue, Esmon, Charles T., Wu, Depei, Xu, Jun
Published in Blood advances (14.06.2022)
Published in Blood advances (14.06.2022)
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Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice
Shaw, Maureen A., Kombrinck, Keith W., McElhinney, Kathryn E., Sweet, David R., Flick, Matthew J., Palumbo, Joseph S., Cheng, Mei, Esmon, Naomi L., Esmon, Charles T., Brill, Alexander, Wagner, Denisa D., Degen, Jay L., Mullins, Eric S.
Published in Blood (04.08.2016)
Published in Blood (04.08.2016)
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The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A
Flick, Matthew J., Chauhan, Anil K., Frederick, Malinda, Talmage, Kathryn E., Kombrinck, Keith W., Miller, Whitney, Mullins, Eric S., Palumbo, Joseph S., Zheng, Xunzhen, Esmon, Naomi L., Esmon, Charles T., Thornton, Sherry, Becker, Ann, Pelc, Leslie A., Di Cera, Enrico, Wagner, Denisa D., Degen, Jay L.
Published in Blood (09.06.2011)
Published in Blood (09.06.2011)
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Extraembryonic expression of EPCR is essential for embryonic viability
Li, Weihong, Zheng, Xunzhen, Gu, Jian-Ming, Ferrell, Gary L., Brady, Mingming, Esmon, Naomi L., Esmon, Charles T.
Published in Blood (15.10.2005)
Published in Blood (15.10.2005)
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Disruption of the Endothelial Cell Protein C Receptor Gene in Mice Causes Placental Thrombosis and Early Embryonic Lethality
Gu, Jian-Ming, Crawley, James T B, Ferrell, Gary, Zhang, Fangjiu, Li, Weihong, Esmon, Naomi L, Esmon, Charles T
Published in The Journal of biological chemistry (08.11.2002)
Published in The Journal of biological chemistry (08.11.2002)
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Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice
Zheng, Xunzhen, Li, Weihong, Gu, Jian-Ming, Qu, Dongfeng, Ferrell, Gary L., Esmon, Naomi L., Esmon, Charles T.
Published in Blood (01.02.2007)
Published in Blood (01.02.2007)
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Journal Article
Endothelial protein C receptor
Esmon, C T, Xu, J, Gu, J M, Qu, D, Laszik, Z, Ferrell, G, Stearns-Kurosawa, D J, Kurosawa, S, Taylor, Jr, F B, Esmon, N L
Published in Thrombosis and haemostasis (01.08.1999)
Published in Thrombosis and haemostasis (01.08.1999)
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Journal Article
Metalloproteolytic Release of Endothelial Cell Protein C Receptor
Xu, Jun, Qu, Dongfeng, Esmon, Naomi L., Esmon, Charles T.
Published in The Journal of biological chemistry (25.02.2000)
Published in The Journal of biological chemistry (25.02.2000)
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