Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods
Adriaens, Els, Barroso, João, Eskes, Chantra, Hoffmann, Sebastian, McNamee, Pauline, Alépée, Nathalie, Bessou-Touya, Sandrine, De Smedt, Ann, De Wever, Bart, Pfannenbecker, Uwe, Tailhardat, Magalie, Zuang, Valérie
Published in Archives of toxicology (01.03.2014)
Published in Archives of toxicology (01.03.2014)
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Journal Article
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom–Up and Top–Down approaches
Scott, Laurie, Eskes, Chantra, Hoffmann, Sebastian, Adriaens, Els, Alepée, Nathalie, Bufo, Monica, Clothier, Richard, Facchini, Davide, Faller, Claudine, Guest, Robert, Harbell, John, Hartung, Thomas, Kamp, Hennicke, Varlet, Béatrice Le, Meloni, Marisa, McNamee, Pauline, Osborne, Rosemarie, Pape, Wolfgang, Pfannenbecker, Uwe, Prinsen, Menk, Seaman, Christopher, Spielmann, Horst, Stokes, William, Trouba, Kevin, Berghe, Christine Van den, Goethem, Freddy Van, Vassallo, Marco, Vinardell, Pilar, Zuang, Valérie
Published in Toxicology in vitro (01.02.2010)
Published in Toxicology in vitro (01.02.2010)
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Journal Article
The HaCaT/THP-1 Cocultured Activation Test (COCAT) for skin sensitization: a study of intra-lab reproducibility and predictivity
Eskes, Chantra, Hennen, Jennifer, Schellenberger, Mario T, Hoffmann, Sebastian, Frey, Sabine, Goldinger-Oggier, Daniela, Peter, Niklas, Van Vliet, Erwin, Blömeke, Brunhilde
Published in ALTEX, alternatives to animal experimentation (2019)
Published in ALTEX, alternatives to animal experimentation (2019)
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Journal Article
Risks for animal and human health related to the presence of polychlorinated naphthalenes (PCNs) in feed and food
Schrenk, Dieter, Bignami, Margherita, Bodin, Laurent, Chipman, James Kevin, Mazo, Jesús, Grasl‐Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Leblanc, Jean‐Charles, Nebbia, Carlo Stefano, Ntzani, Evangelia, Petersen, Annette, Sand, Salomon, Schwerdtle, Tanja, Vleminckx, Christiane, Wallace, Heather, Falandysz, Jerzy, Hart, Andrew, Rose, Martin, Anastassiadou, Maria, Eskes, Chantra, Gergelova, Petra, Innocenti, Matteo, Rovesti, Elena, Whitty, Ben, Nielsen, Elsa
Published in EFSA journal (01.03.2024)
Published in EFSA journal (01.03.2024)
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Journal Article
ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test
Spielmann, Horst, Hoffmann, Sebastian, Liebsch, Manfred, Botham, Phil, Fentem, Julia H, Eskes, Chantra, Roguet, Roland, Cotovio, José, Cole, Thomas, Worth, Andrew, Heylings, Jon, Jones, Penny, Robles, Catherine, Kandárova, Helena, Gamer, Armin, Remmele, Marina
Published in Alternatives to laboratory animals (01.12.2007)
Published in Alternatives to laboratory animals (01.12.2007)
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Journal Article
Alternatives to Carbon Dioxide-Taking Responsibility for Humanely Ending the Life of Animals
Axiak Flammer, Shannon, Eskes, Chantra, Kohler, Ingrid, Pernet, Awilo Ochieng, Jakob, Peter, Marahrens, Michael, Gent, Thomas C, Golledge, Huw, Weary, Dan
Published in Animals (Basel) (24.07.2019)
Published in Animals (Basel) (24.07.2019)
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Journal Article
Validation study on the Ocular Irritection® assay for eye irritation testing
Eskes, Chantra, Hoffmann, Sebastian, Facchini, Davide, Ulmer, Rich, Wang, Amy, Flego, Manuela, Vassallo, Marco, Bufo, Monica, van Vliet, Erwin, d’Abrosca, Federica, Wilt, Nathan
Published in Toxicology in vitro (01.08.2014)
Published in Toxicology in vitro (01.08.2014)
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Journal Article
The ECVAM international validation study on in vitro tests for acute skin irritation: selection of test chemicals
Eskes, Chantra, Cole, Thomas, Hoffmann, Sebastian, Worth, Andrew, Cockshott, Amanda, Gerner, Ingrid, Zuang, Valérie
Published in Alternatives to laboratory animals (01.12.2007)
Published in Alternatives to laboratory animals (01.12.2007)
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Journal Article
Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems
Pamies, David, Bal-Price, Anna, Chesné, Christophe, Coecke, Sandra, Dinnyes, Andras, Eskes, Chantra, Grillari, Regina, Gstraunthaler, Gerhard, Hartung, Thomas, Jennings, Paul, Leist, Marcel, Martin, Ulrich, Passier, Robert, Schwamborn, Jens C, Stacey, Glyn N, Ellinger-Ziegelbauer, Heidrun, Daneshian, Mardas
Published in ALTEX, alternatives to animal experimentation (01.01.2018)
Published in ALTEX, alternatives to animal experimentation (01.01.2018)
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Journal Article
Good cell culture practices &in vitro toxicology
Eskes, Chantra, Boström, Ann-Charlotte, Bowe, Gerhard, Coecke, Sandra, Hartung, Thomas, Hendriks, Giel, Pamies, David, Piton, Alain, Rovida, Costanza
Published in Toxicology in vitro (01.12.2017)
Published in Toxicology in vitro (01.12.2017)
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Journal Article
The inter‐laboratory validation study of EpiSensA for predicting skin sensitization potential
Mizumachi, Hideyuki, Watanabe, Mika, Ikezumi, Mayu, Kajiwara, Michika, Yasuda, Michiyo, Mizuno, Makoto, Imai, Noriyasu, Sakuma, Megumi, Shibata, Momoko, Watanabe, Shin‐ichi, Motoyama, Junko, Basketter, David, Eskes, Chantra, Hoffmann, Sebastian, Lehmann, David M., Ashikaga, Takao, Sozu, Takashi, Takeyoshi, Masahiro, Suzuki, Sho, Miyazawa, Masaaki, Kojima, Hajime
Published in Journal of applied toxicology (01.04.2024)
Published in Journal of applied toxicology (01.04.2024)
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Journal Article
Value and limitation of in vitro bioassays to support the application of the threshold of toxicological concern to prioritise unidentified chemicals in food contact materials
Schilter, Benoit, Burnett, Karin, Eskes, Chantra, Geurts, Lucie, Jacquet, Mélanie, Kirchnawy, Christian, Oldring, Peter, Pieper, Gabriele, Pinter, Elisabeth, Tacker, Manfred, Traussnig, Heinz, Van Herwijnen, Peter, Boobis, Alan
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (02.12.2019)
Published in Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment (02.12.2019)
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Journal Article
Inter-laboratory performance of ICE histopathology scoring to identify UN GHS Category 1 surfactants and non-extreme pH detergents
Eskes, Chantra, Wijnands, Marcel V.W., Hermann, Martina, Prinsen, Menk, Bertein, Caroline, Byrne, Dominic, Kreutzer, Robert, Mowat, Vasanthi, Taylor, Ian, van Vliet, Erwin, Weber, Klaus
Published in Regulatory toxicology and pharmacology (01.11.2021)
Published in Regulatory toxicology and pharmacology (01.11.2021)
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Journal Article
Integrated Testing Strategies (ITS) for safety assessment
Rovida, Costanza, Alépée, Nathalie, Api, Anne M, Basketter, David A, Bois, Frédéric Y, Caloni, Francesca, Corsini, Emanuela, Daneshian, Mardas, Eskes, Chantra, Ezendam, Janine, Fuchs, Horst, Hayden, Patrick, Hegele-Hartung, Christa, Hoffmann, Sebastian, Hubesch, Bruno, Jacobs, Miriam N, Jaworska, Joanna, Kleensang, André, Kleinstreuer, Nicole, Lalko, Jon, Landsiedel, Robert, Lebreux, Frédéric, Luechtefeld, Thomas, Locatelli, Monica, Mehling, Annette, Natsch, Andreas, Pitchford, Jonathan W, Prater, Donald, Prieto, Pilar, Schepky, Andreas, Schüürmann, Gerrit, Smirnova, Lena, Toole, Colleen, van Vliet, Erwin, Weisensee, Dirk, Hartung, Thomas
Published in ALTEX, alternatives to animal experimentation (2015)
Published in ALTEX, alternatives to animal experimentation (2015)
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Journal Article