Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors
Eshleman, Amy J., Nagarajan, Shanthi, Wolfrum, Katherine M., Reed, John F., Nilsen, Aaron, Torralva, Randy, Janowsky, Aaron
Published in Biochemical pharmacology (01.12.2020)
Published in Biochemical pharmacology (01.12.2020)
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Journal Article
Substituted methcathinones differ in transporter and receptor interactions
Eshleman, Amy J., Wolfrum, Katherine M., Hatfield, Meagan G., Johnson, Robert A., Murphy, Kevin V., Janowsky, Aaron
Published in Biochemical pharmacology (15.06.2013)
Published in Biochemical pharmacology (15.06.2013)
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Journal Article
Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release
Eshleman, Amy J, Wolfrum, Katherine M, Reed, John F, Kim, Sunyoung O, Swanson, Tracy, Johnson, Robert A, Janowsky, Aaron
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2017)
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Journal Article
Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function
Shi, Xiao, Walter, Nicole A R, Harkness, John H, Neve, Kim A, Williams, Robert W, Lu, Lu, Belknap, John K, Eshleman, Amy J, Phillips, Tamara J, Janowsky, Aaron
Published in PloS one (31.03.2016)
Published in PloS one (31.03.2016)
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Journal Article
Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters
Eshleman, Amy J., Nagarajan, Shanthi, Wolfrum, Katherine M., Reed, John F., Swanson, Tracy L., Nilsen, Aaron, Janowsky, Aaron
Published in Psychopharmacology (01.03.2019)
Published in Psychopharmacology (01.03.2019)
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Journal Article
Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors
Eshleman, Amy J., Wolfrum, Katherine M., Reed, John F., Kim, Sunyoung O., Johnson, Robert A., Janowsky, Aaron
Published in Biochemical pharmacology (01.12.2018)
Published in Biochemical pharmacology (01.12.2018)
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Journal Article
Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters
Torralva, Randy, Eshleman, Amy J., Swanson, Tracy L., Schmachtenberg, Jennifer L., Schutzer, William E., Bloom, Shelley H., Wolfrum, Katherine M., Reed, John F., Janowsky, Aaron
Published in The Journal of pharmacology and experimental therapeutics (01.09.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2020)
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Journal Article
Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT)2A Receptor (5-HT2AR), 5-HT2CR, 5-HT1AR, and Serotonin Transporter
Kozell, Laura B, Eshleman, Amy J, Swanson, Tracy L, Bloom, Shelley H, Wolfrum, Katherine M, Schmachtenberg, Jennifer L, Olson, Randall J, Janowsky, Aaron, Abbas, Atheir I
Published in The Journal of pharmacology and experimental therapeutics (01.04.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2023)
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Journal Article
Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D2-Like Receptor Signaling in Dysglycemia
Bonifazi, Alessandro, Ellenberger, Michael, Farino, Zachary J, Aslanoglou, Despoina, Rais, Rana, Pereira, Sandra, Mantilla-Rivas, José O, Boateng, Comfort A, Eshleman, Amy J, Janowsky, Aaron, Hahn, Margaret K, Schwartz, Gary J, Slusher, Barbara S, Newman, Amy Hauck, Freyberg, Zachary
Published in Diabetes (New York, N.Y.) (01.09.2024)
Published in Diabetes (New York, N.Y.) (01.09.2024)
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Journal Article
Pharmacologic Characterization of Substituted Nitazenes at μ , κ , and Δ Opioid Receptors Suggests High Potential for Toxicity
Kozell, Laura B, Eshleman, Amy J, Wolfrum, Katherine M, Swanson, Tracy L, Bloom, Shelley H, Benware, Sheila, Schmachtenberg, Jennifer L, Schutzer, Kamryn A, Schutzer, William E, Janowsky, Aaron, Abbas, Atheir I
Published in The Journal of pharmacology and experimental therapeutics (01.05.2024)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2024)
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Journal Article
A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder
Galaj, Ewa, Bi, Guo-Hua, Klein, Benjamin, Hempel, Briana, Shaik, Anver Basha, Gogarnoiu, Emma S., Friedman, Jacob, Lam, Jenny, Rais, Rana, Reed, John F., Bloom, Shelley H., Swanson, Tracy L., Schmachtenberg, Jennifer L., Eshleman, Amy J., Janowsky, Aaron, Xi, Zheng-Xiong, Newman, Amy Hauck
Published in Neuropsychopharmacology (New York, N.Y.) (01.12.2022)
Published in Neuropsychopharmacology (New York, N.Y.) (01.12.2022)
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Journal Article
Pharmacologic Activity of Substituted Tryptamines at 5-Hydroxytryptamine (5-HT) 2A Receptor (5-HT 2A R), 5-HT 2C R, 5-HT 1A R, and Serotonin Transporter
Kozell, Laura B, Eshleman, Amy J, Swanson, Tracy L, Bloom, Shelley H, Wolfrum, Katherine M, Schmachtenberg, Jennifer L, Olson, Randall J, Janowsky, Aaron, Abbas, Atheir I
Published in The Journal of pharmacology and experimental therapeutics (01.04.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2023)
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Journal Article
Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function
Eshleman, Amy J., Forster, Michael J., Wolfrum, Katherine M., Johnson, Robert A., Janowsky, Aaron, Gatch, Michael B.
Published in Psychopharmacology (01.03.2014)
Published in Psychopharmacology (01.03.2014)
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Journal Article
New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263
Ofori, Edward, Onyameh, Edem K., Gonela, Uma M., Voshavar, Chandrashekhar, Bricker, Barbara, Swanson, Tracy L., Eshleman, Amy J., Schmachtenberg, Jennifer L., Bloom, Shelley H., Janowsky, Aaron J., Ablordeppey, Seth Y.
Published in European journal of medicinal chemistry (15.03.2021)
Published in European journal of medicinal chemistry (15.03.2021)
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Journal Article
Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation
Antonio, Tamara, Childers, Steven R, Rothman, Richard B, Dersch, Christina M, King, Christine, Kuehne, Martin, Bornmann, William G, Eshleman, Amy J, Janowsky, Aaron, Simon, Eric R, Reith, Maarten E A, Alper, Kenneth
Published in PloS one (16.10.2013)
Published in PloS one (16.10.2013)
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Journal Article
Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters
Tosh, Dilip K, Janowsky, Aaron, Eshleman, Amy J, Warnick, Eugene, Gao, Zhan-Guo, Chen, Zhoumou, Gizewski, Elizabeth, Auchampach, John A, Salvemini, Daniela, Jacobson, Kenneth A
Published in Journal of medicinal chemistry (13.04.2017)
Published in Journal of medicinal chemistry (13.04.2017)
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Journal Article
Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter
Provencher, Brian A, Eshleman, Amy J, Johnson, Robert A, Shi, Xiao, Kryatova, Olga, Nelson, Jared, Tian, Jianhua, Gonzalez, Mario, Meltzer, Peter C, Janowsky, Aaron
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Journal Article
Verification of a genetic locus for methamphetamine intake and the impact of morphine
Eastwood, Emily C., Eshleman, Amy J., Janowsky, Aaron, Phillips, Tamara J.
Published in Mammalian genome (01.04.2018)
Published in Mammalian genome (01.04.2018)
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Journal Article