Neutralization of Acidic Tumor Microenvironment (TME) with Daily Oral Dosing of Sodium Potassium Citrate (K/Na Citrate) Increases Therapeutic Effect of Anti-cancer Agent in Pancreatic Cancer Xenograft Mice Model
Ando, Hidenori, Eshima, Kiyoshi, Ishida, Tatsuhiro
Published in Biological & pharmaceutical bulletin (01.02.2021)
Published in Biological & pharmaceutical bulletin (01.02.2021)
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Increasing Tumor Extracellular pH by an Oral Alkalinizing Agent Improves Antitumor Responses of Anti-PD-1 Antibody: Implication of Relationships between Serum Bicarbonate Concentrations, Urinary pH, and Therapeutic Outcomes
Ando, Hidenori, Emam, Sherif E., Kawaguchi, Yoshino, Shimizu, Taro, Ishima, Yu, Eshima, Kiyoshi, Ishida, Tatsuhiro
Published in Biological & pharmaceutical bulletin (01.06.2021)
Published in Biological & pharmaceutical bulletin (01.06.2021)
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The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: A comparison between direct sequencing and real-time PCR
Kobunai, Takashi, Watanabe, Toshiaki, Yamamoto, Yoko, Eshima, Kiyoshi
Published in Biochemical and biophysical research communications (23.04.2010)
Published in Biochemical and biophysical research communications (23.04.2010)
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Heterogeneity of KRAS Status May Explain the Subset of Discordant KRAS Status Between Primary and Metastatic Colorectal Cancer
Watanabe, Toshiaki, Kobunai, Takashi, Yamamoto, Yoko, Matsuda, Keiji, Ishihara, Soichiro, Nozawa, Keijiro, Iinuma, Hisae, Shibuya, Hajime, Eshima, Kiyoshi
Published in Diseases of the colon & rectum (01.09.2011)
Published in Diseases of the colon & rectum (01.09.2011)
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A novel intraperitoneal therapy for gastric cancer with DFP‐10825, a unique RNAi therapeutic targeting thymidylate synthase, in a peritoneally disseminated xenograft model
Ando, Hidenori, Fukushima, Masakazu, Eshima, Kiyoshi, Hasui, Taichi, Shimizu, Taro, Ishima, Yu, Huang, Cheng‐Long, Wada, Hiromi, Ishida, Tatsuhiro
Published in Cancer medicine (Malden, MA) (01.12.2019)
Published in Cancer medicine (Malden, MA) (01.12.2019)
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Gene expression signature and response to the use of leucovorin, fluorouracil and oxaliplatin in colorectal cancer patients
Watanabe, Toshiaki, Kobunai, Takashi, Yamamoto, Yoko, Matsuda, Keiji, Ishihara, Soichiro, Nozawa, Keijiro, Iinuma, Hisae, Konishi, Tsuyoshi, Horie, Hisanaga, Ikeuchi, Hiroki, Eshima, Kiyoshi, Muto, Tetsuichiro
Published in Clinical & translational oncology (01.06.2011)
Published in Clinical & translational oncology (01.06.2011)
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Predicting Ulcerative Colitis-Associated Colorectal Cancer Using Reverse-Transcription Polymerase Chain Reaction Analysis
Watanabe, Toshiaki, Kobunai, Takashi, Yamamoto, Yoko, Ikeuchi, Hiroki, Matsuda, Keiji, Ishihara, Soichiro, Nozawa, Keijiro, Iinuma, Hisae, Kanazawa, Takamitsu, Tanaka, Toshiaki, Yokoyama, Tadashi, Konishi, Tsuyoshi, Eshima, Kiyoshi, Ajioka, Yohichi, Hibi, Toshifumi, Watanabe, Mamoru, Muto, Tetsuichiro, Nagawa, Hirokazu
Published in Clinical colorectal cancer (01.06.2011)
Published in Clinical colorectal cancer (01.06.2011)
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A polyethylene glycol-conjugate of deoxycytidine analog, DFP-14927, produces potential antitumor effects on pancreatic tumor-xenograft murine models via inducing G2/M arrest
Ando, Hidenori, Eshima, Kiyoshi, Ishida, Tatsuhiro
Published in European journal of pharmacology (05.07.2023)
Published in European journal of pharmacology (05.07.2023)
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Journal Article
Oral administration of sodium bicarbonate can enhance the therapeutic outcome of Doxil® via neutralizing the acidic tumor microenvironment
Ando, Hidenori, Ikeda, Ai, Tagami, Maho, Matsuo, Nana Cristina Amorim, Shimizu, Taro, Ishima, Yu, Eshima, Kiyoshi, Ishida, Tatsuhiro
Published in Journal of controlled release (01.10.2022)
Published in Journal of controlled release (01.10.2022)
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Journal Article
Analysis of the prolonged infusion of DFP-10917, a deoxycytidine analog, as a therapeutic strategy for the treatment of human tumor xenografts in vivo
Iizuka, Kenzo, Zhang, Chun, Eshima, Kokoro, Jin, Cheng, Eshima, Kiyoshi, Fukushima, Masakazu
Published in International journal of oncology (01.03.2018)
Published in International journal of oncology (01.03.2018)
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Abstract 5099: Development of novel antimetabolite, DFP-11207, with self-toxicity protection and its promising preclinical and clinical profiles
Fukushima, Masakazu, Iizuka, Kenzo, Eshima, Kokoro, Zhang, Chung, Jin, Cheng, Eshima, Kiyoshi, Ajani, Jaffer
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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