Current Approaches for Absorption, Distribution, Metabolism, and Excretion Characterization of Antibody-Drug Conjugates: An Industry White Paper
Kraynov, Eugenia, Kamath, Amrita V, Walles, Markus, Tarcsa, Edit, Deslandes, Antoine, Iyer, Ramaswamy A, Datta-Mannan, Amita, Sriraman, Priya, Bairlein, Michaela, Yang, Johnny J, Barfield, Matthew, Xiao, Guangqing, Escandon, Enrique, Wang, Weirong, Rock, Dan A, Chemuturi, Nagendra V, Moore, David J
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Published in Drug metabolism and disposition (01.05.2016)
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Published in The Journal of neuroscience (01.03.1994)
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Limitations of employing antibody drug conjugates (ADCs) for targeting HIV infected cells as a strategy for hiv cure
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Regulation of neurotrophin receptor expression during embryonic and postnatal development
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Published in The Journal of neuroscience (01.04.1994)
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Neurotrophin gene expression by cell lines derived from human gliomas
Hamel, W, Westphal, M, Szönyi, E, Escandón, E, Nikolics, K
Published in Journal of neuroscience research (01.02.1993)
Published in Journal of neuroscience research (01.02.1993)
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Tissue Disposition and Pharmacokinetics of Recombinant Human Nerve Growth Factor after Acute and Chronic Subcutaneous Administration in Monkeys
Nguyen, C B, Harris, L, Szönyi, E, Baughman, S A, Hale, V G, Dybdal, N O, Sadick, M D, Escandón, E
Published in Drug metabolism and disposition (01.05.2000)
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Published in Drug metabolism and disposition (01.05.2000)
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Stability and Interactions of Recombinant Human Nerve Growth Factor in Different Biological Matrices: In Vitro and In Vivo Studies
Cindy B. Nguyen, Ãva Szönyi, Michael D. Sadick, Timothy E. Hotaling, Jose-Luis Mendoza-Ramirez, Enrique Escandón
Published in Drug metabolism and disposition (01.05.2000)
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Published in Drug metabolism and disposition (01.05.2000)
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The Role of Anti-Drug Antibodies in the Pharmacokinetics, Disposition, Target Engagement, and Efficacy of a GITR Agonist Monoclonal Antibody in Mice
Brunn, Nicholas D, Mauze, Smita, Gu, Danling, Wiswell, Derek, Ueda, Roanna, Hodges, Douglas, Beebe, Amy M, Zhang, Shuli, Escandón, Enrique
Published in The Journal of pharmacology and experimental therapeutics (01.03.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2016)
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Preclinical Pharmacokinetics, Interspecies Scaling, and Tissue Distribution of a Humanized Monoclonal Antibody against Vascular Endothelial Growth Factor
Lin, Y S, Nguyen, C, Mendoza, J L, Escandon, E, Fei, D, Meng, Y G, Modi, N B
Published in The Journal of pharmacology and experimental therapeutics (01.01.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1999)
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Xiang, Hong, Nguyen, Cindy B, Kelley, Sean K, Dybdal, Noel, Escandón, Enrique
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Published in Drug metabolism and disposition (01.11.2004)
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PP 9.1 - Limitations of employing antibody drug conjugates (ADCs) for targeting HIV infected cells as a strategy for hiv cure
Strizki, J., Graham, D., Lu, M., Wu, G., Breslin, M., Davis, N., Escandon, E., Fayadat-Dilman, L., Zheng, Y., Barnard, R., Garbaccio, R., Manibusan, A., Bhowmik, S., Gately, D., Sun, Y., Gorman, D.
Published in Journal of Virus Eradication (01.12.2015)
Published in Journal of Virus Eradication (01.12.2015)
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Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection
Beaumont, Maribel, Tomazela, Daniela, Hodges, Douglas, Ermakov, Grigori, Hsieh, Edward, Figueroa, Isabel, So, On-Yee, Song, Yaoli, Ma, Huiping, Antonenko, Svetlana, Mengesha, Wondwessen, Zhang, Yi Wei, Zhang, Shuli, Hseih, SuChun, Ayanoglu, Gulesi, Du, Xiaoyan, Rimmer, Eric, Judo, Michael, Vives, Franklin, Yearley, Jennifer H., Moon, Christina, Manibusan, Anthony, Knudsen, Nick, Beck, Andy, Bresson, Damien, Gately, Dennis, Neupane, Divas, Escandón, Enrique
Published in AAPS open (08.08.2018)
Published in AAPS open (08.08.2018)
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Characterization of a CC49-Based Single-Chain Fragment−β-Lactamase Fusion Protein for Antibody-Directed Enzyme Prodrug Therapy (ADEPT)
Alderson, Ralph F, Toki, Brian E, Roberge, Martin, Geng, Wei, Basler, Joshua, Chin, Regina, Liu, Amy, Ueda, Roanna, Hodges, Douglas, Escandon, Enrique, Chen, Tianling, Kanavarioti, Tessi, Babé, Lilia, Senter, Peter D, Fox, Judith A, Schellenberger, Volker
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Published in Bioconjugate chemistry (01.03.2006)
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HONG XIANG, FOX, Judith A, TOTPAL, Klara, AIKAWA, Mina, DUPREE, Kelly, SINICROPI, Dominick, LOWE, John, ESCANDON, Enrique
Published in Oncogene (16.05.2002)
Published in Oncogene (16.05.2002)
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Characterization of neurotrophin receptors by affinity crosslinking
Escandón, E, Burton, L E, Szönyi, E, Nikolics, K
Published in Journal of neuroscience research (15.04.1993)
Published in Journal of neuroscience research (15.04.1993)
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The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells
Tsoulfas, Pantelis, Soppet, Dan, Escandon, Enrique, Tessarollo, Lino, Mendoza-Ramirez, José-Luis, Rosenthal, Arnon, Nikolics, Karoly, Parada, Luis F.
Published in Neuron (Cambridge, Mass.) (01.05.1993)
Published in Neuron (Cambridge, Mass.) (01.05.1993)
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The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor
Soppet, Dan, Escandon, Enrique, Maragos, Johnne, Middlemas, David S., Raid, Susan W., Blair, Janet, Burton, Louis E., Stanton, Brian R., Kaplan, David R., Hunter, Tony, Nikolics, Karoly, Parade, Luis F.
Published in Cell (31.05.1991)
Published in Cell (31.05.1991)
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