Spectral Accuracy of Molecular Ions in an LTQ/Orbitrap Mass Spectrometer and Implications for Elemental Composition Determination
Erve, John C.L., Gu, Ming, Wang, Yongdong, DeMaio, William, Talaat, Rasmy E.
Published in Journal of the American Society for Mass Spectrometry (01.11.2009)
Published in Journal of the American Society for Mass Spectrometry (01.11.2009)
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Journal Article
Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate
Zhang, Yong-Kang, Plattner, Jacob J, Easom, Eric E, Jacobs, Robert T, Guo, Denghui, Freund, Yvonne R, Berry, Pamela, Ciaravino, Vic, Erve, John C. L, Rosenthal, Philip J, Campo, Brice, Gamo, Francisco-Javier, Sanz, Laura M, Cao, Jianxin
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
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Journal Article
Bioactivation of Sitaxentan in Liver Microsomes, Hepatocytes, and Expressed Human P450s with Characterization of the Glutathione Conjugate by Liquid Chromatography Tandem Mass Spectrometry
Erve, John C. L, Gauby, Shawn, Maynard, John W, Svensson, Mats A, Tonn, George, Quinn, Kevin P
Published in Chemical research in toxicology (17.06.2013)
Published in Chemical research in toxicology (17.06.2013)
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Journal Article
Characterization of Glutathione Conjugates of Duloxetine by Mass Spectrometry and Evaluation of in Silico Approaches to Rationalize the Site of Conjugation for Thiophene Containing Drugs
Wu, Guosheng, Vashishtha, Sarvesh C, Erve, John C. L
Published in Chemical research in toxicology (16.08.2010)
Published in Chemical research in toxicology (16.08.2010)
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Journal Article
Metabolism of Prazosin in Rat, Dog, and Human Liver Microsomes and Cryopreserved Rat and Human Hepatocytes and Characterization of Metabolites by Liquid Chromatography/Tandem Mass Spectrometry
ERVE, John C. L, VASHISHTHA, Sarvesh C, DEMAIO, William, TALAAT, Rasmy E
Published in Drug metabolism and disposition (01.06.2007)
Published in Drug metabolism and disposition (01.06.2007)
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Journal Article
Mass Spectral Peak Distortion Due to Fourier Transform Signal Processing
Rockwood, Alan L., Erve, John C. L.
Published in Journal of the American Society for Mass Spectrometry (01.12.2014)
Published in Journal of the American Society for Mass Spectrometry (01.12.2014)
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Journal Article
Characterization of Glutathione Conjugates of the Remoxipride Hydroquinone Metabolite NCQ-344 Formed in Vitro and Detection following Oxidation by Human Neutrophils
Erve, John C. L, Svensson, Mats A, von Euler-Chelpin, Hans, Klasson-Wehler, Eva
Published in Chemical research in toxicology (01.04.2004)
Published in Chemical research in toxicology (01.04.2004)
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Journal Article
Metabolite identification in rat brain microdialysates by direct infusion nanoelectrospray ionization after desalting on a ZipTip and LTQ/Orbitrap mass spectrometry
Erve, John C. L., Beyer, Chad E., Manzino, Lawrence, Talaat, Rasmy E.
Published in Rapid communications in mass spectrometry (30.12.2009)
Published in Rapid communications in mass spectrometry (30.12.2009)
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Journal Article
Metabolism of Intravenous Methylnaltrexone in Mice, Rats, Dogs, and Humans
CHANDRASEKARAN, Appavu, TONG, Zeen, SCATINA, Joann, HONGSHAN LI, ERVE, John C. L, DEMAIO, William, GOLJER, Igor, MCCONNELL, Oliver, ROTSHTEYN, Yakov, HULTIN, Theresa, TALAAT, Rasmy
Published in Drug metabolism and disposition (01.04.2010)
Published in Drug metabolism and disposition (01.04.2010)
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Journal Article
HIGHLY SELECTIVE INHIBITION OF HUMAN CYP3A IN VITRO BY AZAMULIN AND EVIDENCE THAT INHIBITION IS IRREVERSIBLE
STRESSER, David M, BROUDY, Marc I, PATTEN, Christopher J, DEHAL, Shangara S, CRESPI, Charles L, THUY HO, CARGILL, Catherine E, BLANCHARD, Andrew P, SHARMA, Raman, DANDENEAU, Andre A, GOODWIN, Joseph J, TURNER, Stephanie D, ERVE, John C. L
Published in Drug metabolism and disposition (01.01.2004)
Published in Drug metabolism and disposition (01.01.2004)
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Journal Article
In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin
Grillo, Mark P., Erve, John C. L., Dick, Ryan, Driscoll, James P., Haste, Nicole, Markova, Svetlana, Brun, Priscilla, Carlson, Timothy J., Evanchik, Marc
Published in Xenobiotica (03.06.2019)
Published in Xenobiotica (03.06.2019)
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Journal Article
Rapid metabolite identification with sub parts-per-million mass accuracy from biological matrices by direct infusion nanoelectrospray ionization after clean-up on a ZipTip and LTQ/Orbitrap mass spectrometry
Erve, John C. L., DeMaio, William, Talaat, Rasmy E.
Published in Rapid communications in mass spectrometry (15.10.2008)
Published in Rapid communications in mass spectrometry (15.10.2008)
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Journal Article
In vitro metabolism and identification of human enzymes involved in the metabolism of methylnaltrexone
Tong, Zeen, Chandrasekaran, Appavu, Li, Hongshan, Rotshteyn, Yakov, Erve, John C L, Demaio, William, Talaat, Rasmy, Hultin, Theresa, Scatina, JoAnn
Published in Drug metabolism and disposition (01.05.2010)
Published in Drug metabolism and disposition (01.05.2010)
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Journal Article
Substrate-Dependent Modulation of CYP3A4 Catalytic Activity: Analysis of 27 Test Compounds with Four Fluorometric Substrates
STRESSER, David M, BLANCHARD, Andrew P, TURNER, Stephanie D, ERVE, John C. L, DANDENEAU, Andre A, MILLER, Vaughn P, CRESPI, Charles L
Published in Drug metabolism and disposition (01.12.2000)
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Published in Drug metabolism and disposition (01.12.2000)
Journal Article
Characterization of a Valine−Lysine Thiourea Cross-Link on Rat Globin Produced by Carbon Disulfide or N,N-Diethyldithiocarbamate in Vivo
Erve, John C. L, Amarnath, Venkataraman, Sills, Robert C, Morgan, D. L, Valentine, William M
Published in Chemical research in toxicology (01.10.1998)
Published in Chemical research in toxicology (01.10.1998)
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Journal Article