The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
Liu, Ilon, Jiang, Li, Samuelsson, Erik R., Marco Salas, Sergio, Beck, Alexander, Hack, Olivia A., Jeong, Daeun, Shaw, McKenzie L., Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa M., Madlener, Sibylle, Mayr, Lisa, Quezada, Michael A., Trissal, Maria, Panditharatna, Eshini, Ernst, Kati J., Vogelzang, Jayne, Gatesman, Taylor A., Halbert, Matthew E., Palova, Hana, Pokorna, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac J., Dun, Matthew D., Resnick, Adam, Suvà, Mario L., Jones, David T. W., Agnihotri, Sameer, Svedlund, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer A., Ligon, Keith L., Alexandrescu, Sanda, Yung, W. K. Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella G.
Published in Nature genetics (01.12.2022)
Published in Nature genetics (01.12.2022)
Get full text
Journal Article
A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
Hai, Ling, Hoffmann, Dirk C., Wagener, Robin J., Azorin, Daniel D., Hausmann, David, Xie, Ruifan, Huppertz, Magnus-Carsten, Hiblot, Julien, Sievers, Philipp, Heuer, Sophie, Ito, Jakob, Cebulla, Gina, Kourtesakis, Alexandros, Kaulen, Leon D., Ratliff, Miriam, Mandelbaum, Henriette, Jung, Erik, Jabali, Ammar, Horschitz, Sandra, Ernst, Kati J., Reibold, Denise, Warnken, Uwe, Venkataramani, Varun, Will, Rainer, Suvà, Mario L., Herold-Mende, Christel, Sahm, Felix, Winkler, Frank, Schlesner, Matthias, Wick, Wolfgang, Kessler, Tobias
Published in Nature communications (06.02.2024)
Published in Nature communications (06.02.2024)
Get full text
Journal Article
Author Correction: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Ghasemi, David R., Okonechnikov, Konstantin, Rademacher, Anne, Tirier, Stephan, Maass, Kendra K., Schumacher, Hanna, Joshi, Piyush, Gold, Maxwell P., Sundheimer, Julia, Statz, Britta, Rifaioglu, Ahmet S., Bauer, Katharina, Schumacher, Sabrina, Bortolomeazzi, Michele, Giangaspero, Felice, Ernst, Kati J., Clifford, Steven C., Saez-Rodriguez, Julio, Jones, David T. W., Kawauchi, Daisuke, Fraenkel, Ernest, Mallm, Jan-Philipp, Rippe, Karsten, Korshunov, Andrey, Pfister, Stefan M., Pajtler, Kristian W.
Published in Nature communications (04.10.2024)
Published in Nature communications (04.10.2024)
Get full text
Journal Article
Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage
Ghasemi, David R., Okonechnikov, Konstantin, Rademacher, Anne, Tirier, Stephan, Maass, Kendra K., Schumacher, Hanna, Joshi, Piyush, Gold, Maxwell P., Sundheimer, Julia, Statz, Britta, Rifaioglu, Ahmet S., Bauer, Katharina, Schumacher, Sabrina, Bortolomeazzi, Michele, Giangaspero, Felice, Ernst, Kati J., Clifford, Steven C., Saez-Rodriguez, Julio, Jones, David T. W., Kawauchi, Daisuke, Fraenkel, Ernest, Mallm, Jan-Philipp, Rippe, Karsten, Korshunov, Andrey, Pfister, Stefan M., Pajtler, Kristian W.
Published in Nature communications (08.01.2024)
Published in Nature communications (08.01.2024)
Get full text
Journal Article
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy
Zuckermann, Marc, He, Chen, Andrews, Jared, Bagchi, Aditi, Sloan-Henry, Roketa, Bianski, Brandon, Xie, Jia, Wang, Yingzhe, Twarog, Nathaniel, Onar-Thomas, Arzu, Ernst, Kati J, Yang, Lei, Li, Yong, Zhu, Xiaoyan, Ocasio, Jennifer K, Budd, Kaitlin M, Dalton, James, Li, Xiaoyu, Chepyala, Divyabharathi, Zhang, Junyuan, Xu, Ke, Hover, Laura, Roach, Jordan T, Chan, Kenneth Chun-Ho, Hofmann, Nina, McKinnon, Peter J, Pfister, Stefan M, Shelat, Anang A, Rankovic, Zoran, Freeman, 3rd, Burgess B, Chiang, Jason, Jones, David T W, Tinkle, Christopher L, Baker, Suzanne J
Published in Molecular cancer (07.06.2024)
Published in Molecular cancer (07.06.2024)
Get full text
Journal Article
BIOL-07. DISTINCTIVE FEATURES OF HIGH-GRADE GLIOMA MOUSE MODELS REVEALED BY SINGLE-NUCLEUS RNA-SEQUENCING GUIDE PRE-CLINICAL MODEL SELECTION
Ernst, Kati, Okonechnikov, Konstantin, von Soosten, Laura, Hofmann, Nina, Mack, Norman, Schwalm, Benjamin, Wechsler-Reya, Robert J, Pfister, Stefan M, Thongjuea, Supat, Jones, David T W, Zuckermann, Marc
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Get full text
Journal Article
MEDB-60. Medulloblastoma with extensive nodularity mimics cerebellar development and differentiates along the granular precursor lineage
Ghasemi, David R, Okonechnikov, Konstantin, Tirier, Stephan, Rademacher, Anne, Mallm, Jan-Philipp, Ernst, Kati, Rippe, Karsten, Korshunov, Andrey, Pfister, Stefan M, Pajtler, Kristian W
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Get full text
Journal Article
ATRT-28. SINGLE NUCLEI SEQUENCING REVEALS THE DIFFERENT PHENOTYPIC COMPOSITION OF THE ATRT SUBGROUPS
Johann, Pascal, Büllesbach, Annette, Ernst, Kati, Okonechnikov, Konstantin, Jones, David T W, Pfister, Stefan M, Hasselblatt, Martin, Kool, Marcel
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Get full text
Journal Article
CNSC-09. CHI3L1 IS A MOLECULAR MARKER FOR GLIOBLASTOMA NETWORK CONNECTIVITY AND FUNCTIONALLY ORCHESTRATES TUMOR MICROTUBE FORMATION
Hoffmann, Dirk, Hai, Ling, Wagener, Robin, Hausmann, David, Azorín, Daniel Domínguez, Xie, Ruifan, Huppertz, Magnus-Carsten, Hiblot, Julien, Sievers, Philipp, Ito, Jakob, Weil, Sophie, Cebulla, Gina, Mandelbaum, Henriette, Jung, Erik, Kourtesakis, Alexandros, Ernst, Kati, Reibold, Denise, Warnken, Uwe, Venkataramani, Varun, Will, Rainer, Suva, Mario, Herold-Mende, Christel, Sahm, Felix, Winkler, Frank, Schlesner, Matthias, Wick, Wolfgang, Kessler, Tobias
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Get full text
Journal Article
MBRS-03. SINGLE NUCLEUS TRANSCRIPTOME PROFILES FROM HUMAN DEVELOPING CEREBELLUM REVEAL POTENTIAL CELLULAR ORIGINS OF MEDULLOBLASTOMA BRAIN TUMORS
Okonechnikov, Konstantin, Sepp, Mari, Leiss, Kevin, Kutscher, Lena, Ernst, Kati, Jones, David, Jäger, Natalie, Pajtler, Kristian W, Kaessmann, Henrik, Pfister, Stefan M
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Published in Neuro-oncology (Charlottesville, Va.) (04.12.2020)
Get full text
Journal Article
METB-03. SOLID PEDIATRIC TUMORS IN MICE REVEAL MODEL-SPECIFIC GLOBAL DNA METHYLATION AND CNV PROFILES CORRESPONDING TO HUMAN COUNTERPARTS
Schoof, Melanie, Zheng, Tuyu, Sill, Martin, Imle, Roland, Hofmann, Nina, Ernst, Kati, Vonficht, Dominik, Chan, Chun Ho, Cais, Alessia, Holland-Letz, Tim, Postlmayr, Andreas, Shiraishi, Ryo, Wang, Wanchen, Morcavallo, Alaide, Spohn, Michael, Göbel, Carolin, Niesen, Judith, Peter, Levke-Sophie, Eckhardt, Alicia, Bourdeaut, Franck, Han, Zhi-Yan, Pei, Yanxin, Murad, Najiba, Swartling, Fredrik J, Taylor, Jessica, Gilbertson, Richard J, Dottermusch, Matthias, Kerl, Kornelius, Glass, Rainer, Cheng, Jiying, Horstmann, Martin A, Nollau, Peter, Wolters-Eisfeld, Gerrit, Zhao, Haotian, Sturm, Dominik, Chesler, Louis, Haas, Simon, Weiss, William A, Northcott, Paul A, Kutscher, Lena M, Stücklin, Ana Guerreiro, Ayrault, Olivier, Neumann, Julia E, Kawauchi, Daisuke, Jones, David, Pfister, Stefan M, Pajtler, Kristian, Banito, Ana, Schüller, Ulrich, Zuckermann, Marc
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Get full text
Journal Article
MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma
Zuckermann, Marc, He, Chen, Andrews, Jared, Sloan-Henry, Roketa, Bianski, Brandon, Xie, Jia, Wang, Yingzhe, Twarog, Nathaniel, Onar-Thomas, Arzu, Ernst, Kati, Yang, Lei, Li, Yong, Dalton, James, Li, Xiaoyu, Chepyala, Divyabharathi, Zhu, Xiaoyan, Zhang, Junyuan, Xu, Ke, Hover, Laura, McKinnon, Peter J, Pfister, Stefan M, Rankovic, Zoran, Freeman, Burgess B, Shelat, Anang A, Chiang, Jason, Jones, David T W, Tinkle, Christopher L, Baker, Suzanne J
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Published in Neuro-oncology (Charlottesville, Va.) (03.06.2022)
Get full text
Journal Article
DIPG-08. THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION
Liu, Ilon, Jiang, Li, Samuelsson, Erik, Salas, Sergio Marco, Beck, Alexander, Hack, Olivia, Jeong, Daeun, Shaw, McKenzie, Englinger, Bernhard, LaBelle, Jenna, Mire, Hafsa, Madlener, Sibylle, Mayr, Lisa, Quezada, Michael, Trissal, Maria, Panditharatna, Eshini, Ernst, Kati, Vogelzang, Jayne, Gatesman, Taylor, Halbert, Matthew, Palova, Hana, Vesela, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Findlay, Izac, Dun, Matt, Resnick, Adam, Suva, Mario, Jones, David, Agnihotri, Sameer, Ostlin, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer, Ligon, Keith, Alexandrescu, Sanda, Yung, W K Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Get full text
Journal Article
EPCO-06. AGE- AND REGION-SPECIFIC MULTI-OMIC CHARACTERIZATION OF H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA
Liu, Ilon, Li, Jiang, Jeong, Daeun, Hack, Olivia A, Shaw, McKenzie, Englinger, Bernhard, Avihai, Byron, Ernst, Kati, Resnick, Adam, Diaz, Aaron, Jones, David, Koschmann, Carl, Kleinman, Claudia, Jabado, Nada, Cotter, Jennifer, Ligon, Keith, Alexandrescu, Sanda, Yung, W K Alfred, Czech, Thomas, Arrillaga-Romany, Isabel, Gojo, Johannes, Slavc, Irene, Monje, Michelle, Filbin, Mariella G
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.11.2021)
Get full text
Journal Article
EPCO-21. THE SPATIAL ORGANIZATION OF H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA
Liu, Ilon, Li, Jiang, Samuelsson, Erik, Salas, Sergio Marco, Beck, Alexander, Hack, Olivia, Jeong, Daeun, Shaw, McKenzie, Englinger, Bernhard, Labelle, Jenna, Mire, Hafsa, Madlener, Sibylle, Mayr, Lisa, Quezada, Michael, Trissal, Maria, Panditharatna, Eshini, Ernst, Kati, Gatesman, Taylor, Halbert, Matthew, Palova, Hana, Pokorna, Petra, Sterba, Jaroslav, Slaby, Ondrej, Geyeregger, Rene, Diaz, Aaron, Resnick, Adam C, Suva, Mario, Jones, David, Agnihotri, Sameer, Ostlin, Jessica, Koschmann, Carl, Haberler, Christine, Czech, Thomas, Slavc, Irene, Cotter, Jennifer, Ligon, Keith, Alexandrescu, Sanda, Yung, W K Alfred, Arrillaga-Romany, Isabel, Gojo, Johannes, Monje, Michelle, Nilsson, Mats, Filbin, Mariella
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Get full text
Journal Article
Establishment of a simplified preparation method for single-nucleus RNA-sequencing and its application to long-term frozen tumor tissues
Ernst, Kati J, Okonechnikov, Konstantin, Bageritz, Josephine, Jan-Philipp Mallm, Wittmann, Andrea, Maaß, Kendra K, Leible, Svenja, Boutros, Michael, Pfister, Stefan M, Zuckermann, Marc, Jones, David Tw
Published in bioRxiv (23.10.2020)
Published in bioRxiv (23.10.2020)
Get full text
Paper
DEVICE FOR TESTING MEMBRANES
Neumann, Nico, Kappel, Stefan, Bombien, Günter, Ernst, Kati, Schäfer, Martin, Epple, Sebastian
Year of Publication 06.11.2019
Get full text
Year of Publication 06.11.2019
Patent
DEVICE FOR TESTING MEMBRANES
Neumann, Nico, Kappel, Stefan, Bombien, Günter, Ernst, Kati, Schäfer, Martin, Epple, Sebastian
Year of Publication 15.05.2019
Get full text
Year of Publication 15.05.2019
Patent