Oncogenic partnerships: EWS-FLI1 protein interactions initiate key pathways of Ewing's sarcoma
Erkizan, Hayriye V, Uversky, Vladimir N, Toretsky, Jeffrey A
Published in Clinical cancer research (15.08.2010)
Published in Clinical cancer research (15.08.2010)
Get full text
Journal Article
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing
Selvanathan, Saravana P., Graham, Garrett T., Erkizan, Hayriye V., Dirksen, Uta, Natarajan, Thanemozhi G., Dakic, Aleksandra, Yu, Songtao, Liu, Xuefeng, Paulsen, Michelle T., Ljungman, Mats E., Wu, Cathy H., Lawlor, Elizabeth R., Üren, Aykut, Toretsky, Jeffrey A.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Get full text
Journal Article
Combining PARP-1 inhibition and radiation in Ewing sarcoma results in lethal DNA damage
Lee, Hae-June, Yoon, Changhwan, Schmidt, Benjamin, Park, Do Joong, Zhang, Alexia Y, Erkizan, Hayriye V, Toretsky, Jeffrey A, Kirsch, David G, Yoon, Sam S
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
Get full text
Journal Article
Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1
Barber-Rotenberg, Julie S, Selvanathan, Saravana P, Kong, Yali, Erkizan, Hayriye V, Snyder, Tara M, Hong, S Peter, Kobs, Christina L, South, Natalie L, Summer, Steven, Monroe, Philip J, Chruszcz, Maksymilian, Dobrev, Veselin, Tosso, Perrer N, Scher, Lauren J, Minor, Wladek, Brown, Milton L, Metallo, Steven J, Üren, Aykut, Toretsky, Jeffrey A
Published in Oncotarget (29.02.2012)
Published in Oncotarget (29.02.2012)
Get full text
Journal Article
Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors
Erkizan, Hayriye V., Scher, Lauren J., Gamble, S. Ellen, Barber-Rotenberg, Julie S., Sajwan, Kamal P., Üren, Aykut, Toretsky, Jeffrey A.
Published in Cell cycle (Georgetown, Tex.) (01.10.2011)
Published in Cell cycle (Georgetown, Tex.) (01.10.2011)
Get full text
Journal Article
Human β defensin-1 and -2 expression in the gingiva of patients with specific periodontal diseases
Vardar-Sengul, S., Demirci, T., Sen, B. H., Erkizan, V., Kurulgan, E., Baylas, H.
Published in Journal of periodontal research (01.10.2007)
Published in Journal of periodontal research (01.10.2007)
Get full text
Journal Article
Retraction: Combining PARP-1 Inhibition and Radiation in Ewing Sarcoma Results in Lethal DNA Damage
Lee, Hae-June, Yoon, Changhwan, Schmidt, Benjamin, Park, Do Joong, Zhang, Alexia Y., Erkizan, Hayriye V., Toretsky, Jeffrey A., Kirsch, David G., Yoon, Sam S.
Published in Molecular cancer therapeutics (04.11.2024)
Published in Molecular cancer therapeutics (04.11.2024)
Get full text
Journal Article
A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma
Toretsky, Jeffrey A, Erkizan, Hayriye V, Kong, Yali, Merchant, Melinda, Schlottmann, Silke, Barber-Rotenberg, Julie S, Yuan, Linshan, Abaan, Ogan D, Chou, Tsu-hang, Dakshanamurthy, Sivanesan, Brown, Milton L, Üren, Aykut
Published in Nature medicine (01.07.2009)
Published in Nature medicine (01.07.2009)
Get full text
Journal Article
Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in Ewing Sarcoma
Hong, Sung-Hyeok, Youbi, Sarah E, Hong, S Peter, Kallakury, Bhaskar, Monroe, Phillip, Erkizan, Hayriye V, Barber-Rotenberg, Julie S, Houghton, Peter, Üren, Aykut, Toretsky, Jeffrey A
Published in Oncotarget (30.01.2014)
Published in Oncotarget (30.01.2014)
Get full text
Journal Article
Inhibition of the oncogenic fusion protein EWS-FLI1 causes G 2 -M cell cycle arrest and enhanced vincristine sensitivity in Ewing's sarcoma
Zöllner, Stefan K, Selvanathan, Saravana P, Graham, Garrett T, Commins, Ryan M T, Hong, Sung Hyeok, Moseley, Eric, Parks, Sydney, Haladyna, Jessica N, Erkizan, Hayriye V, Dirksen, Uta, Hogarty, Michael D, Üren, Aykut, Toretsky, Jeffrey A
Published in Science signaling (03.10.2017)
Published in Science signaling (03.10.2017)
Get more information
Journal Article
RETRACTED: Combining PARP-1 Inhibition and Radiation in Ewing Sarcoma Results in Lethal DNA Damage
Lee, Hae-June, Yoon, Changhwan, Schmidt, Benjamin, Park, Do Joong, Zhang, Alexia Y., Erkizan, Hayriye V., Toretsky, Jeffrey A., Kirsch, David G., Yoon, Sam S.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
Get full text
Journal Article
Abstract 485: EWS-FLI1 targeted small molecule YK-4-279 synergizes with vinca alkaloids through double hit to mitotic machinery
Zöllner, Stefan K., Commins, Ryan, Hong, Sung H., Erkizan, Hayriye V., Toretsky, Jeffrey A.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Get full text
Journal Article
Abstract 54: Ezrin enhances signaling and nuclear translocation of the epidermal growth factor receptor in non-small cell lung cancer cells
Saygideger Kont, Yasemin, Celik, Haydar, Erkizan, Hayriye V., Minas, Tsion, Han, Jenny, Toretsky, Jeffrey, Uren, Aykut
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Get full text
Journal Article
Evidence for Borrelia burgdorferi in morphea and lichen sclerosus
Özkan, S˛ebnem, Atabey, Nes˛e, Fetil, Emel, Erkızan, Verda, Günes˛, Ali Tahsin
Published in International journal of dermatology (01.04.2000)
Published in International journal of dermatology (01.04.2000)
Get full text
Journal Article
Combining poly(ADP-ribose) polymerase 1 (PARP-1) inhibition and radiation in Ewing sarcoma results in lethal DNA damage
Lee, Hae-June, Yoon, Changhwan, Schmidt, Benjamin, Park, Do Joong, Zhang, Alexia Y., Erkizan, Hayriye V., Toretsky, Jeffrey A., Kirsch, David G., Yoon, Sam S.
Published in Molecular cancer therapeutics (21.08.2013)
Published in Molecular cancer therapeutics (21.08.2013)
Get full text
Journal Article