AB‐Bind: Antibody binding mutational database for computational affinity predictions
Sirin, Sarah, Apgar, James R., Bennett, Eric M., Keating, Amy E.
Published in Protein science (01.02.2016)
Published in Protein science (01.02.2016)
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Modeling and mitigation of high-concentration antibody viscosity through structure-based computer-aided protein design
Apgar, James R, Tam, Amy S P, Sorm, Rhady, Moesta, Sybille, King, Amy C, Yang, Han, Kelleher, Kerry, Murphy, Denise, D'Antona, Aaron M, Yan, Guoying, Zhong, Xiaotian, Rodriguez, Linette, Ma, Weijun, Ferguson, Darren E, Carven, Gregory J, Bennett, Eric M, Lin, Laura
Published in PloS one (07.05.2020)
Published in PloS one (07.05.2020)
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Reduction of therapeutic antibody self-association using yeast-display selections and machine learning
Makowski, Emily K, Chen, Hongwei, Lambert, Matthew, Bennett, Eric M, Eschmann, Nicole S, Zhang, Yulei, Zupancic, Jennifer M, Desai, Alec A, Smith, Matthew D, Lou, Wenjia, Fernando, Amendra, Tully, Timothy, Gallo, Christopher J, Lin, Laura, Tessier, Peter M
Published in mAbs (2022)
Published in mAbs (2022)
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Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody
Campbell, Sharon M, DeBartolo, Joseph, Apgar, James R, Mosyak, Lydia, McManus, Virginie, Beyer, Sonia, Bennett, Eric M, Lambert, Matthew, Cunningham, Orla
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Identification of pyrimidine derivatives as hSMG-1 inhibitors
Gopalsamy, Ariamala, Bennett, Eric M., Shi, Mengxiao, Zhang, Wei-Guo, Bard, Joel, Yu, Ker
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Journal Article
A Mechanism-Based Aryl Carrier Protein/Thiolation Domain Affinity Probe
Qiao, Chunhua, Wilson, Daniel J, Bennett, Eric M, Aldrich, Courtney C
Published in Journal of the American Chemical Society (23.05.2007)
Published in Journal of the American Chemical Society (23.05.2007)
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PF-06804103, A Site-specific Anti-HER2 Antibody–Drug Conjugate for the Treatment of HER2-expressing Breast, Gastric, and Lung Cancers
Graziani, Edmund I., Sung, Matthew, Ma, Dangshe, Narayanan, Bitha, Marquette, Kimberly, Puthenveetil, Sujiet, Tumey, L. Nathan, Bikker, Jack, Casavant, Jeffrey, Bennett, Eric M., Charati, Manoj B., Golas, Jonathon, Hosselet, Christine, Rohde, Cynthia M., Hu, George, Guffroy, Magali, Falahatpisheh, Hadi, Finkelstein, Martin, Clark, Tracey, Barletta, Frank, Tchistiakova, Lioudmila, Lucas, Judy, Rosfjord, Edward, Loganzo, Frank, O'Donnell, Christopher J., Gerber, Hans-Peter, Sapra, Puja
Published in Molecular cancer therapeutics (01.10.2020)
Published in Molecular cancer therapeutics (01.10.2020)
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Site Selection: a Case Study in the Identification of Optimal Cysteine Engineered Antibody Drug Conjugates
Tumey, L. Nathan, Li, Fengping, Rago, Brian, Han, Xiaogang, Loganzo, Frank, Musto, Sylvia, Graziani, Edmund I., Puthenveetil, Sujiet, Casavant, Jeffrey, Marquette, Kimberly, Clark, Tracey, Bikker, Jack, Bennett, Eric M., Barletta, Frank, Piche-Nicholas, Nicole, Tam, Amy, O’Donnell, Christopher J., Gerber, Hans Peter, Tchistiakova, Lioudmila
Published in The AAPS journal (01.07.2017)
Published in The AAPS journal (01.07.2017)
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Journal Article
Morpholine Derivatives Greatly Enhance the Selectivity of Mammalian Target of Rapamycin (mTOR) Inhibitors
Zask, Arie, Kaplan, Joshua, Verheijen, Jeroen C, Richard, David J, Curran, Kevin, Brooijmans, Natasja, Bennett, Eric M, Toral-Barza, Lourdes, Hollander, Irwin, Ayral-Kaloustian, Semiramis, Yu, Ker
Published in Journal of medicinal chemistry (24.12.2009)
Published in Journal of medicinal chemistry (24.12.2009)
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Journal Article
Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and Integrase
Wang, Zhengqiang, Bennett, Eric M, Wilson, Daniel J, Salomon, Christine, Vince, Robert
Published in Journal of medicinal chemistry (26.07.2007)
Published in Journal of medicinal chemistry (26.07.2007)
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Journal Article
Rationally Designed Nucleoside Antibiotics That Inhibit Siderophore Biosynthesis of Mycobacterium tuberculosis
SOMU, Ravindranadh V., BOSHOFF, Helena, QIAO, Chunhua, BENNETT, Eric M., BARRY, Clifton E., ALDRICH, Courtney C.
Published in Journal of medicinal chemistry (12.01.2006)
Published in Journal of medicinal chemistry (12.01.2006)
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Inhibition of Siderophore Biosynthesis in Mycobacterium tuberculosis with Nucleoside Bisubstrate Analogues: Structure−Activity Relationships of the Nucleobase Domain of 5′-O-[N-(Salicyl)sulfamoyl]adenosine
Neres, João, Labello, Nicholas P, Somu, Ravindranadh V, Boshoff, Helena I, Wilson, Daniel J, Vannada, Jagadeshwar, Chen, Liqiang, Barry, Clifton E, Bennett, Eric M, Aldrich, Courtney C
Published in Journal of medicinal chemistry (11.09.2008)
Published in Journal of medicinal chemistry (11.09.2008)
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Identification and optimization of indolo[2,3-c]quinoline inhibitors of IRAK4
Tumey, L. Nathan, Boschelli, Diane H., Bhagirath, Niala, Shim, Jaechul, Murphy, Elizabeth A., Goodwin, Deborah, Bennett, Eric M., Wang, Mengmeng, Lin, Lih-Ling, Press, Barry, Shen, Marina, Frisbie, Richard K., Morgan, Paul, Mohan, Shashi, Shin, Julia, Rao, Vikram R.
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
Published in Bioorganic & medicinal chemistry letters (01.05.2014)
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5‘-O-[(N-Acyl)sulfamoyl]adenosines as Antitubercular Agents that Inhibit MbtA: An Adenylation Enzyme Required for Siderophore Biosynthesis of the Mycobactins
Qiao, Chunhua, Gupte, Amol, Boshoff, Helena I, Wilson, Daniel J, Bennett, Eric M, Somu, Ravindranadh V, Barry, Clifton E, Aldrich, Courtney C
Published in Journal of medicinal chemistry (29.11.2007)
Published in Journal of medicinal chemistry (29.11.2007)
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Journal Article
Design, Synthesis, and Biological Evaluation of β-Ketosulfonamide Adenylation Inhibitors as Potential Antitubercular Agents
Vannada, Jagadeshwar, Bennett, Eric M, Wilson, Daniel J, Boshoff, Helena I, Barry, Clifton E, Aldrich, Courtney C
Published in Organic letters (12.10.2006)
Published in Organic letters (12.10.2006)
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Journal Article
Antitubercular Nucleosides That Inhibit Siderophore Biosynthesis: SAR of the Glycosyl Domain
Somu, Ravindranadh V, Wilson, Daniel J, Bennett, Eric M, Boshoff, Helena I, Celia, Laura, Beck, Brian J, Barry, Clifton E, Aldrich, Courtney C
Published in Journal of medicinal chemistry (28.12.2006)
Published in Journal of medicinal chemistry (28.12.2006)
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